WO2000049971A1 - Prothese endovasculaire a flexibilite sur mesure - Google Patents

Prothese endovasculaire a flexibilite sur mesure Download PDF

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Publication number
WO2000049971A1
WO2000049971A1 PCT/US2000/004323 US0004323W WO0049971A1 WO 2000049971 A1 WO2000049971 A1 WO 2000049971A1 US 0004323 W US0004323 W US 0004323W WO 0049971 A1 WO0049971 A1 WO 0049971A1
Authority
WO
WIPO (PCT)
Prior art keywords
stent
cylindrical elements
interconnecting members
portions
interconnecting
Prior art date
Application number
PCT/US2000/004323
Other languages
English (en)
Inventor
Daniel L. Cox
Original Assignee
Advanced Cardiovascular Systems, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Advanced Cardiovascular Systems, Inc. filed Critical Advanced Cardiovascular Systems, Inc.
Priority to JP2000600585A priority Critical patent/JP2002537064A/ja
Priority to EP00911881A priority patent/EP1154735A1/fr
Priority to AU33704/00A priority patent/AU3370400A/en
Publication of WO2000049971A1 publication Critical patent/WO2000049971A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/9522—Means for mounting a stent or stent-graft onto or into a placement instrument
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
    • A61F2/958—Inflatable balloons for placing stents or stent-grafts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91508—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other the meander having a difference in amplitude along the band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91516—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other the meander having a change in frequency along the band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91575—Adjacent bands being connected to each other connected peak to trough
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0002—Two-dimensional shapes, e.g. cross-sections
    • A61F2230/0004—Rounded shapes, e.g. with rounded corners
    • A61F2230/0013—Horseshoe-shaped, e.g. crescent-shaped, C-shaped, U-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0029—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in bending or flexure capacity

Definitions

  • Stents generally are cylindrically-shaped devices which function to hold open and sometimes to expand a segment of a blood vessel or other lumen, such as a coronary artery. Stents are particularly suitable for use to support the lumen or to hold back a dissected arterial lining which can occlude the fluid passageway therethrough.
  • a variety of devices are known in the art for use as stents and have included balloon expandable stents; coiled wires in a variety of patterns that are expanded after being placed intraluminally on a balloon catheter; helically- wound coiled springs manufactured from an expandable, heat sensitive metal; and self-expanding stents inserted in a compressed state and shaped in a zigzag pattern.
  • One of the difficulties encountered using prior art stents involved maintaining the radial rigidity needed to hold open a body lumen while at the same time maintaining the longitudinal flexibility of the stent to facilitate its delivery and to accommodate the often tortuous path of the body lumen.
  • Another problem area has been the limited range of expandability.
  • One problem with the prior art stents has been contraction of the stent along its longitudinal axis upon radial expansion of the stent. This can cause placement problems within the artery during expansion.
  • Various means have been described to deliver and implant stents.
  • One method frequently described for delivering a stent to a desired intraluminal location includes mounting the expandable stent on an expandable member, such as a balloon, provided on the distal end of an intra vascular catheter, advancing the catheter to the desired location within the patient's body lumen, inflating the balloon on the catheter to expand the stent into a permanent expanded condition, and then deflating the balloon and removing the catheter.
  • the present invention is directed to stents of enhanced longitudinal flexibility and configuration which permit the stents to expand radially to accommodate a greater number of different diameter vessels, both large and small, than heretofore was possible.
  • the stents also have greater flexibility along the longitudinal axis to facilitate delivery through tortuous body lumens, but remain highly stable when expanded radially, to maintain the patency of a body lumen such as an artery or other vessel when implanted therein.
  • the unique patterns of the stents of the instant invention permit both greater longitudinal flexibility and enhanced radial expandability and stability compared to prior art stents.
  • Each of the stents of the present invention can be readily delivered to the desired lumenal location by mounting onto an expandable member, such as a balloon, of a delivery catheter and passing the catheter-stent assembly through the body lumen to the implantation site.
  • an expandable member such as a balloon
  • a variety of means for securing the stents to the expandable member of the catheter for delivery to the desired location are available. It presently is preferred to compress or crimp the stent onto the unexpanded balloon.
  • Other means to secure the stent to the balloon include providing ridges or collars on the inflatable member to restrain lateral movement, using bioabsorbable temporary adhesives, or adding a retractable sheath to cover the stent during delivery through a body lumen.
  • the stiffest portion could be located over the heaviest plaque mass. This region would have minimal separation or splay between the cylindrical elements and would therefore minimize tissue prolapse.
  • the flexible ends of the stent would conform to the vessel and minimize the length of artery which is forced to be more straight by an otherwise rigid stent. The more flexible end sections also would be positioned closer to the normal portion of the artery where splay would be a less important factor. This assumes the stent has a length that is sufficient to cover the lesion and extends from a normal portion of the vessel to another normal portion of the vessel.
  • FIG. 3 is a side elevational view, partially in section, showing the expanded stent within the vessel after withdrawal of the delivery catheter.
  • FIG. 4 is a plan view of a flattened section of one embodiment of the present invention stent which illustrates the serpentine pattern and the varying number of interconnecting members of the stent so that one end is more flexible than the other.
  • FIG. 6 is a perspective view of the stent of FIG. 4 in the expanded configuration.
  • FIG. 8 is a plan view of a flattened section of another embodiment of the present invention stent wherein the number of interconnecting members is varied to obtain flexible end sections.
  • the stent of the present invention optionally adds at least one more repeating pattern of U-, Y-, and W-shaped members to each cylindrical ring. Further, two connecting members, spaced 180 degrees apart between adjacent cylindrical rings, provide for increased flexibility over the prior art stents, which is essential for delivering the present invention stent through tortuous anatomy and implanting it in a curved section of vessel.
  • FIG. 1 illustrates a first embodiment of a stent 10 incorporating features of the present invention which is mounted onto a delivery catheter 11.
  • the stent generally comprises a plurality of radially expandable cylindrical elements 12 disposed generally coaxially and interconnected by interconnecting members 13 disposed between adjacent cylindrical elements 12.
  • the delivery catheter 11 has an expandable portion or balloon 14 for expanding the stent 10 within an artery 15 or other vessel.
  • the artery 15, as shown in FIG. 1, has a dissected or detached lining 16 which has occluded a portion of the arterial passageway.
  • a retractable protective delivery sleeve 20 may be provided to ensure that the stent 10 stays in place on the balloon 14 of the delivery catheter 11 and to prevent abrasion of the body lumen from the open surface of the stent 10 during delivery to the desired arterial location.
  • Other means for securing the stent 10 onto the balloon 14 also may be used, such as providing collars or ridges on the ends of the working portion, j ⁇ e., the cylindrical portion, of the balloon 14.
  • Each radially expandable cylindrical element 12 of the stent 10 may be independently expanded. Therefore, the balloon 14 may be provided with an inflated shape other than cylindrical, e ⁇ , tapered, to facilitate implantation of the stent 10 in a variety of body lumen shapes.
  • the undulating component of the cylindrical elements of the stent 10 is relatively flat in a transverse cross-section so that when the stent 10 is expanded, the cylindrical elements 12 are pressed into the wall of the artery 1 and, as a result, do not interfere with the blood flow through the artery 15.
  • the cylindrical elements 12 of the stent 10 that are pressed into the wall of the artery 15 eventually will be covered with endothelial cell growth which growth further minimizes blood flow turbulence.
  • the serpentine pattern of the cylindrical sections 12 provide good tacking characteristics to prevent stent movement within the artery.
  • FIG. 7 illustrates an alternative embodiment of a stent according to the present invention.
  • FIG. 7 illustrates an alternative embodiment of a stent according to the present invention.
  • FIG. 7 illustrates an alternative embodiment of a stent according to the present invention.
  • the stents of the present invention each have an overall expansion ratio of about 1.0 up to about 4.0 times the original diameter, or more, using certain compositions of stainless steel.
  • a 316L stainless steel stent of the invention can be radially expanded from a diameter of 1.0 unit up to a diameter of about 4.0 units, which expansion deforms the structural members beyond the elastic limit. The stents still retain structural integrity in the expanded state and will serve to hold open the vessel in which the stents are implanted. Materials other than stainless steel (316L) may afford higher or lower expansion ratios without sacrificing structural integrity.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Optics & Photonics (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)

Abstract

L'invention concerne une prothèse endovasculaire extensible destinée à être implantée dans une lumière d'un corps, telle qu'une artère. La prothèse endovasculaire comporte plusieurs éléments cylindriques à extension radiale, alignés en général sur un axe longitudinal commun de la prothèse et interconnectés par un ou plusieurs éléments d'interconnexion placés de telle sorte que la prothèse soit flexible dans le sens de la longueur. Au moins une des extrémités opposées de la prothèse comporte moins d'éléments d'interconnexion qu'une section centrale de la prothèse, ce qui donne une flexibilité localisée à une région sélectionnée de la prothèse endovasculaire.
PCT/US2000/004323 1999-02-26 2000-02-18 Prothese endovasculaire a flexibilite sur mesure WO2000049971A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
JP2000600585A JP2002537064A (ja) 1999-02-26 2000-02-18 カスタマイズされた柔軟性を有するステント
EP00911881A EP1154735A1 (fr) 1999-02-26 2000-02-18 Prothese endovasculaire a flexibilite sur mesure
AU33704/00A AU3370400A (en) 1999-02-26 2000-02-18 Stent with customized flexibility

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25823299A 1999-02-26 1999-02-26
US09/258,232 1999-02-26

Publications (1)

Publication Number Publication Date
WO2000049971A1 true WO2000049971A1 (fr) 2000-08-31

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ID=22979661

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/004323 WO2000049971A1 (fr) 1999-02-26 2000-02-18 Prothese endovasculaire a flexibilite sur mesure

Country Status (4)

Country Link
EP (1) EP1154735A1 (fr)
JP (1) JP2002537064A (fr)
AU (1) AU3370400A (fr)
WO (1) WO2000049971A1 (fr)

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10253633A1 (de) * 2002-11-13 2004-05-27 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Tragstruktur
EP1304091A3 (fr) * 2001-05-25 2005-03-02 Medinol Ltd. Stent flexible longitudinalement
US7141062B1 (en) 2000-03-01 2006-11-28 Medinol, Ltd. Longitudinally flexible stent
WO2007024484A1 (fr) * 2005-08-26 2007-03-01 Medlogics Device Corporation Endoprotheses a lumieres multiples et procedes permettant de realiser des endoprotheses a lumieres multiples presentant plusieurs configurations ouvertes/fermees
WO2007131798A1 (fr) * 2006-05-17 2007-11-22 Angiomed Gmbh & Co. Medizintechnik Kg prothÈse tubulaire capable de se recourber
WO2011129917A1 (fr) * 2010-04-12 2011-10-20 Abbott Cardiovascular Systems Inc. Rapport de forme pour la conception d'entretoises d'endoprothèse
WO2011149598A1 (fr) * 2010-05-28 2011-12-01 Abbott Cardiovascular Systems Inc. Endoprothèse à rapport d'expansion optimisé
US8152842B2 (en) 2006-08-21 2012-04-10 C. R. Bard, Inc. Self-expanding stent
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US8475520B2 (en) 2006-12-06 2013-07-02 C. R. Bard, Inc. Stenting ring with marker
US8500793B2 (en) 2006-09-07 2013-08-06 C. R. Bard, Inc. Helical implant having different ends
USRE44463E1 (en) 2000-08-18 2013-08-27 Angiomed Gmbh & Co. Medizintechnik Kg Implant with attached element and method of making such an implant
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US9039755B2 (en) 2003-06-27 2015-05-26 Medinol Ltd. Helical hybrid stent
US9155639B2 (en) 2009-04-22 2015-10-13 Medinol Ltd. Helical hybrid stent
US9161849B1 (en) 2000-03-01 2015-10-20 Medinol Ltd. Longitudinally flexible stent
US9254207B2 (en) 2006-08-29 2016-02-09 C.R. Bard, Inc. Annular mesh
US9456910B2 (en) 2003-06-27 2016-10-04 Medinol Ltd. Helical hybrid stent
US9622888B2 (en) 2006-11-16 2017-04-18 W. L. Gore & Associates, Inc. Stent having flexibly connected adjacent stent elements
US10299948B2 (en) 2014-11-26 2019-05-28 W. L. Gore & Associates, Inc. Balloon expandable endoprosthesis
US10568752B2 (en) 2016-05-25 2020-02-25 W. L. Gore & Associates, Inc. Controlled endoprosthesis balloon expansion
US10842657B2 (en) 2017-08-21 2020-11-24 Cook Medical Technologies Llc Braided stent crown geometry and flare

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US7141062B1 (en) 2000-03-01 2006-11-28 Medinol, Ltd. Longitudinally flexible stent
US9161849B1 (en) 2000-03-01 2015-10-20 Medinol Ltd. Longitudinally flexible stent
US9968471B1 (en) 2000-03-01 2018-05-15 Medinol Ltd. Longitudinally flexible stent
US8900290B2 (en) 2000-08-17 2014-12-02 Angiomed Gmbh & Co. Medizintechnik Kg Implant with attached element and method of making such an implant
US10213327B2 (en) 2000-08-17 2019-02-26 Angiomed Gmbh & Co. Medizintechnik Kg Implant with attached element and method of making such an implant
US9480587B2 (en) 2000-08-17 2016-11-01 Angiomed Gmbh & Co. Medizintechnik Kg Implant with attached element and method of making such an implant
USRE44463E1 (en) 2000-08-18 2013-08-27 Angiomed Gmbh & Co. Medizintechnik Kg Implant with attached element and method of making such an implant
EP1304091A3 (fr) * 2001-05-25 2005-03-02 Medinol Ltd. Stent flexible longitudinalement
AU2002304381B2 (en) * 2001-05-25 2006-08-24 Medinol, Ltd. Longitudinally flexible stent
US7727272B2 (en) 2002-11-13 2010-06-01 Biotronik Gmbh & Co. Kg Bearing structure
DE10253633B4 (de) * 2002-11-13 2011-08-11 BIOTRONIK GmbH & Co. KG, 12359 Tragstruktur
DE10253633A1 (de) * 2002-11-13 2004-05-27 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Tragstruktur
US9039755B2 (en) 2003-06-27 2015-05-26 Medinol Ltd. Helical hybrid stent
US9456910B2 (en) 2003-06-27 2016-10-04 Medinol Ltd. Helical hybrid stent
US10363152B2 (en) 2003-06-27 2019-07-30 Medinol Ltd. Helical hybrid stent
WO2007024484A1 (fr) * 2005-08-26 2007-03-01 Medlogics Device Corporation Endoprotheses a lumieres multiples et procedes permettant de realiser des endoprotheses a lumieres multiples presentant plusieurs configurations ouvertes/fermees
US8403978B2 (en) 2006-05-17 2013-03-26 C. R. Bard, Inc. Bend-capable tubular prosthesis
US9155642B2 (en) 2006-05-17 2015-10-13 C.R. Bard, Inc. Bend-capable tubular prosthesis
US10849770B2 (en) 2006-05-17 2020-12-01 C. R. Bard, Inc. Bend-capable tubular prosthesis
WO2007131798A1 (fr) * 2006-05-17 2007-11-22 Angiomed Gmbh & Co. Medizintechnik Kg prothÈse tubulaire capable de se recourber
US8574286B2 (en) 2006-05-18 2013-11-05 C. R. Bard, Inc. Bend-capable stent prosthesis
US10231854B2 (en) 2006-05-18 2019-03-19 C. R. Bard, Inc. Bend-capable stent prosthesis
US9364353B2 (en) 2006-05-18 2016-06-14 C.R. Bard, Inc. Bend-capable stent prosthesis
US8152842B2 (en) 2006-08-21 2012-04-10 C. R. Bard, Inc. Self-expanding stent
US9254207B2 (en) 2006-08-29 2016-02-09 C.R. Bard, Inc. Annular mesh
US8500793B2 (en) 2006-09-07 2013-08-06 C. R. Bard, Inc. Helical implant having different ends
US8211163B2 (en) 2006-09-13 2012-07-03 Boston Scientific Scimed, Inc. Hybrid symmetrical stent designs
US9084691B2 (en) 2006-11-10 2015-07-21 C. R. Bard, Inc. Stent
US10500075B2 (en) 2006-11-10 2019-12-10 C. R. Bard, Inc. Stent
US8551156B2 (en) 2006-11-10 2013-10-08 C. R. Bard, Inc. Stent
US9622888B2 (en) 2006-11-16 2017-04-18 W. L. Gore & Associates, Inc. Stent having flexibly connected adjacent stent elements
US10456281B2 (en) 2006-11-16 2019-10-29 W.L. Gore & Associates, Inc. Stent having flexibly connected adjacent stent elements
US8475520B2 (en) 2006-12-06 2013-07-02 C. R. Bard, Inc. Stenting ring with marker
US9050203B2 (en) 2007-04-03 2015-06-09 C. R. Bard, Inc. Bendable stent
US8518101B2 (en) 2007-04-03 2013-08-27 C. R. Bard, Inc. Bendable stent
US8721709B2 (en) 2007-09-07 2014-05-13 C. R. Bard, Inc. Self-expansible stent with radiopaque markers and method of making such a stent
US10016291B2 (en) 2007-09-07 2018-07-10 C. R. Bard, Inc. Self-expansible stent with radiopaque markers and method of making such a stent
US8926688B2 (en) 2008-01-11 2015-01-06 W. L. Gore & Assoc. Inc. Stent having adjacent elements connected by flexible webs
US11865020B2 (en) 2008-01-11 2024-01-09 W. L. Gore & Associates, Inc. Stent having adjacent elements connected by flexible webs
US11103372B2 (en) 2008-01-11 2021-08-31 W. L. Gore & Associates, Inc. Stent having adjacent elements connected by flexible webs
US9943428B2 (en) 2008-01-11 2018-04-17 W. L. Gore & Associates, Inc. Stent having adjacent elements connected by flexible webs
US9155639B2 (en) 2009-04-22 2015-10-13 Medinol Ltd. Helical hybrid stent
WO2011129917A1 (fr) * 2010-04-12 2011-10-20 Abbott Cardiovascular Systems Inc. Rapport de forme pour la conception d'entretoises d'endoprothèse
WO2011149598A1 (fr) * 2010-05-28 2011-12-01 Abbott Cardiovascular Systems Inc. Endoprothèse à rapport d'expansion optimisé
US10543116B2 (en) 2014-11-26 2020-01-28 W. L. Gore & Associates, Inc. Balloon expandable endoprosthesis
US11285029B2 (en) 2014-11-26 2022-03-29 W. L. Gore & Associates, Inc. Balloon expandable endoprosthesis
US11857444B2 (en) 2014-11-26 2024-01-02 W. L. Gore & Associates, Inc. Balloon expandable endoprosthesis
US10299948B2 (en) 2014-11-26 2019-05-28 W. L. Gore & Associates, Inc. Balloon expandable endoprosthesis
US10568752B2 (en) 2016-05-25 2020-02-25 W. L. Gore & Associates, Inc. Controlled endoprosthesis balloon expansion
US11779481B2 (en) 2016-05-25 2023-10-10 W. L. Gore & Associates, Inc. Controlled endoprosthesis balloon expansion
US10842657B2 (en) 2017-08-21 2020-11-24 Cook Medical Technologies Llc Braided stent crown geometry and flare

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