WO2000044422A1

WO2000044422A1 - Injection tablet item package box and injection tablet stored in item package box

Info

Publication number: WO2000044422A1
Application number: PCT/JP1999/006679
Authority: WO
Inventors: Takuji Morita
Original assignee: Eli Lilly Japan K.K.
Priority date: 1999-01-27
Filing date: 1999-11-30
Publication date: 2000-08-03
Also published as: JP2000217910A; AU1412700A; JP2989188B1

Abstract

An injection tablet item package box and an injection tablet stored in the item package box, which can arouse user's attention to the injection tablet by a simple method without using any special member. The item package box (10) for injection tablet has a cutting line (22c) formed in the connecting portion of an inner lid piece (22) on the unsealing port side to make it possible to tear off the inner lid piece (22). The inner lid piece (22) has instructions (22b) indicated thereon concerning the injection tablet and is formed with an insertion hole (22a) so that it can be attached to the injection needle cover (52) of a syringe (50).

Description

Description Individual packaging box for injections and injections stored in individual packagings

The present invention relates to an individual box for injection and an injection stored in the individual box. Background art

Conventionally, various measures have been taken to prevent accidental injection of drugs.

The first method is to display precautionary statements on drug bottles and individual packaging boxes. For example, for a hemostatic agent that may cause a blood clot when injected intravenously, a red, prominent red cautionary note, such as `` No Injection '' or `` No Injection, '' is displayed on the top lid or label of the medicine bottle. Have been. According to this method, the user is warned until the drug is placed in the syringe, but once the drug is placed in the syringe, no warning is given. Therefore, for example, when a nurse station puts a drug into a syringe and transports it to a patient in a separate room, it is insufficient as a countermeasure.

Second, after placing the drug in the syringe, a precautionary note is written directly on the syringe. This method takes time and effort to write the precautionary statement, and may cause erroneous or forgotten writing.

Third, a bag and a sticker with a precautionary note are enclosed in a box, the medicine is put in a syringe, the syringe is put in the bag, and a sticker is attached. This method is implemented in the United States and can be used to display a precautionary notice on a syringe containing a drug without much trouble.

However, special members such as bags, seals, and the like are required, and it is time-consuming to put them in individual packaging boxes at the time of manufacturing, and the individual packaging boxes also need to be large enough to contain them, and therefore, costs are high. In addition, bags and seals are discarded as garbage after use, which wastes resources. Disclosure of the invention Therefore, the technical problem to be solved by the present invention is to provide an individual packaging box for an injection that can be used to alert the user of the injection in a simple manner without using any special member, and to be accommodated in the individual packaging box. To provide an injection.

The present invention, in order to solve the above technical problem, provides an individual box for injection solution having the following configuration.

In the individual packaging box for injections, a display piece that can be attached to the syringe is integrally formed so as to be separable, and a notice is displayed on the display piece. Here, the “syringe” includes a syringe, a syringe needle, a syringe needle cover, a piston rod, etc., regardless of which display piece is attached.

In the above configuration, a vial, ampoule, cartridge or the like containing an injection is usually stored in the packaging box one by one. When preparing an injection, open the packaging box and take out the vial, etc., for example, dissolve the lyophilized agent in the vial and put it in a syringe, or load the cartridge into a syringe equipped with a metering device. A ready-to-use syringe can be fitted with a display strip separated from the packaging so that a precautionary statement is displayed with the syringe attached.

In the precautionary statement, precautionary notes on injections are displayed as appropriate. For example, “Prohibition XXX” and prohibition of specific acts (uses (XXX)), for example, “Prohibition” and use of specific uses (〇〇〇), injection site, injection speed, dosage, etc. Is displayed. The display piece can be formed by using a part of a packaging box that is normally discarded, and the packaging box can store the injection in the same process as in a normal case. . Therefore, it is possible to call attention to injections by a simple method without using special members.

Preferably, a through hole is formed in the display piece so as to pass through a syringe needle cover of the syringe.

According to the configuration described above, a cautionary note can be easily attached to the syringe and displayed by a simple operation of merely inserting the injection needle cover or the like of the syringe into the through hole of the display piece. Further, it is possible to lift and support the needle side of the syringe, for example, by using the display piece, so that the syringe can be stably placed so as not to be rolled. One of the preferred shapes of the through holes is circular. If it is circular, it can be easily inserted into the through hole.

Another preferred shape of the insertion hole is a polygon. If it is a polygon, it is difficult for the display piece to rotate around the injection needle cover etc. inserted into the insertion hole, and it is possible to prevent the cautionary notes from being shifted.

Another preferred shape of the insertion hole is a star. In the case of a star, as in the case of a polygon, it is difficult for the display piece to rotate, and it is possible to prevent the cautionary notes from slipping.However, the injection needle cover etc. is pushed in, and the notch is cut into the notch protruding inside the through hole. With this arrangement, the display piece is more difficult to rotate and the display piece is harder to come off. Preferably, the display piece is formed on a middle lid piece on the opening side of the packaging box. A cut line is formed in the connecting portion of the display piece.

According to the above configuration, the display piece is arranged on the opening side of the packaging box and is always visible when the packaging box is opened, so that the display piece can be kept from being separated. The display piece can be easily torn off and separated by the cut line at the connecting portion of the display piece. In the above configuration, the display piece may consist of only the middle cover piece, may further include a portion continuous with the middle cover piece, or may include only a part of the middle cover piece. Therefore, the cut line of the connecting part of the display piece is formed along the bending line that is the boundary between the inner lid piece and the adjacent part, but is formed at the part that is continuous with the inner lid piece. Alternatively, it may be formed in the middle position of the inner lid piece.

More preferably, the display piece is formed on one of a pair of inner lid pieces on the opening side of the packaging box, and the other is provided with a pictorial display illustrating how to attach the display piece to a syringe. According to the above configuration, when the packaging box is opened, the mounting method of the display piece is illustrated by the pictorial display of the inner lid piece, so that it is easy to understand the mounting method of the display piece. Also, it is possible to make sure that the display piece is attached.

Furthermore, the present invention provides an injection stored in the individual packaging box for injection having the above constitution.

Preferably, a cautionary note indicating prohibition of intrathecal injection is displayed on the display piece of the injection box.

According to the above configuration, accidentally, for example, an anticancer drug used only for intravenous injection, It is particularly suitable for injections that need to be strictly prevented from being administered intrathecally. BRIEF DESCRIPTION OF THE FIGURES

FIG. 1 is a development view of an individual packaging box for an injection according to one embodiment of the present invention.

FIG. 2A, FIG. 2B, and FIG. 2C are explanatory diagrams of how to use the box of FIG.

FIG. 3 is an exploded view of an individual packaging box for injection according to a first modification.

FIG. 4 is a development view of an individual packaging box for injection according to a second modification.

FIG. 5 is an exploded view of an injection box according to a third modification.

FIG. 6 is an exploded view of an injection box according to a fourth modification.

FIG. 7 is an explanatory diagram of how to use the individual box for injections of FIG. BEST MODE FOR CARRYING OUT THE INVENTION

Hereinafter, the individual packaging box for injection solution 10 according to one embodiment of the present invention will be described with reference to the drawings.

As shown in the developed view of FIG. 1, the individual packaging box for injection solution 10 is configured substantially in the same manner as a conventional individual packaging box. In the figure, the fold lines 30 to 40 are indicated by chain lines.

The adhesive strip 11 and the first to fourth strips 12 to 15 are arranged horizontally continuously, and the adhesive strip 11 is bonded to the fourth strip 15 and the first to fourth strips 1 2 15 form the upper, lower, left and right surfaces of the individual box 10. A cut line 1 2b is formed in the upper portion 1 2a of the first standing piece 1 2 and breaks along the cut line 1 2b when the packaging box 10 is opened. It is designed to be separated from the pieces 1 and 2.

Above and below the third standing piece 14, an upper lid piece 21 and a bottom lid piece 17 serving as the top and bottom surfaces of the individual packaging box are connected. The upper lid piece 21 and the bottom lid piece 17 have an upper tongue piece 23 and a lower tongue piece 19 connected to the third standing piece 14 on the opposite side. On the upper and lower sides of the second piece 13 and the fourth piece 15, a middle piece 20, 22 and a lower piece 16, 18 are respectively connected, and an upper piece 21 and a bottom piece 17 are respectively connected. It can be bent more inward. A cut line 22c is formed substantially along the boundary between the fourth standing piece 15 and the inner lid piece 22 so that the inner lid piece 22 can be broken and easily separated.

A circular insertion hole 22a is formed in the center of the inner lid piece 22. 2 2 b is printed. In Fig. 1, Fig. 2A, Fig. 2B and Fig. 2, the precautionary statement 2 2b is shown in a simplified form. It prints with, and draws attention. Any other characters, symbols, figures, etc. may be used in combination as appropriate for the precautionary statement 22b. For example, it displays the name and identification of the injection.

The precautionary statement 22b can draw attention in various ways without being limited to this. For example, the color of the precautionary statement 22 b may be a color other than red, or may be a fluorescent color or an iridescent color that varies depending on the viewing direction. Also, the combination of the ground color and the color of the precautionary statement 2 2 b may make the notice 2 2 b stand out. For example, a purple notice 22b on a yellow background and a gold notice 22b on a black background may be displayed. The ground color may be formed by the name of the manufacturer or injection, the ground pattern of symbols, figures, etc. Furthermore, the periphery of the inner cover piece 22 on which the precautionary statement 22b is printed may be bordered with red or fluorescent color so that the perimeter of the precautionary statement 22b is conspicuous. Alternatively, the portion other than the precautionary statement 2 2b may be a prominent pattern such as black and yellow stripes.

On the other inner cover piece 20, a pictorial indication 20 a of a method of using the separated inner cover piece 22 with the precautionary note 22 b printed thereon is printed. This pictorial display 20a may be omitted.

Illustration of other printing is omitted.

In the same manner as in the conventional case, the individual packaging box 10 has the bonding piece 11 and the fourth piece 15 bonded together, and is bent along the fold lines 3.0 to 40 to form a rectangular parallelepiped shape. For example, a vial is stored. In the individual packaging box 10, the bottom lid piece 17 and the lower lid pieces 16 and 18 are adhered to each other, and the upper tongue piece 23 and the upper part 12a of the first standing piece 12 are connected. They are glued together and sealed.

The packaging box 10 is opened as shown in FIGS. 2A, 2B and 2C, and the inner lid piece is opened.

2 Separate 2 and use for caution.

That is, as shown in Fig. 2A, the upper part 12a of the first standing piece 12 of the packaging box 10 is torn down with a finger and the upper lid piece 21 is opened, and the inner lid piece 2 is opened from the opening. 0 pictogram 2 0 a force S visible. Next, as shown in FIG. 2B, when the middle cover piece 20 is opened, the other middle cover piece 22 is moved. appear. Open this inner lid piece 22 and tear it by hand along the cut line 2 2c and tear it off. Then, the vial is taken out of the packaging box 10 to prepare an injection solution in the syringe 50. When the injection solution is prepared, attach the injection needle cover 52 to the syringe 50, and insert the injection needle cover 52 into the through hole 22a of the middle lid piece 22 as shown in Fig. 2C. Put in. As a result, the precautionary statement 2 2b of the detached inner lid piece 22 is displayed on the syringe 50.

However, as shown in the development views of the individual packaging boxes 10x, 10y, 10z, and 10k of the modified examples of Figs. 3 m is formed, and the part 13 t of the piece 13 3 s is connected to the piece 20 3 s of the inner lid 20 s. As shown in Fig. 7, the torn inner lid piece 20 s and a part of the standing piece 13 s 13 t may be bent and used as shown in Fig. 7. Yeah. In this case, a notice 13 x can be displayed in a large size on a part 13 t of a large piece 13 s of the piece 13 s, which can call attention more effectively. In the example of FIG. 7, a part 13 t of the standing piece 13 s is bent sideways, but may be bent in another manner.For example, a part 13 t of the standing piece 13 s is placed upward. It may be.

In the above modified example, the other part 13 t is torn off along with the entire inner lid piece 20 s, but a cut line is formed at an intermediate position of the inner lid piece 20 s, and the inner lid piece 20 s is cut off. You may leave the part, for example, to tear off only the tip side.

The through holes 20x, 20y, and 20z formed in the inner cover piece 20s that are torn off are not limited to circular shapes, but are triangular insertion holes 20x as shown in FIG. It may be a polygon such as a rectangular through hole 20y as shown in FIG. 4, or a star shaped through hole 20z as shown in FIG. If it is polygonal or star-shaped, the needle cover 52 that penetrates the inner lid piece 20 s not only has a corner in the cross section, but also the inner lid piece 2 even if the cross section is circular. 0 s is difficult to rotate with respect to the injection needle cover 52. In the case of a star shape, by inserting the inserted injection ^ "cover 52 etc. into the jagged part of the star shape, the inner lid piece 20 s becomes harder to rotate around the lower layer and further hardly comes off. As shown in Fig. 6, even if a large number of cut lines 20m are formed around the through hole 20k to make the injection needle cover 52, etc., bite, the inner lid piece 20s becomes difficult to rotate. , And hard to pull out. Also, instead of letting the injection needle cover 52 or the like penetrate the inner lid 20 s having the through holes 20 x, 20 y, 20 ζ, and 20 k from a right angle, the inner lid 20 The injection needle cover 52 may be fitted from the side of s. In this case, instead of the through holes 20x, 20y, 20z, and 2Ok whose surroundings are enclosed, insertion holes continuous from the outside of the inner lid piece 20s, for example, The lid piece 20 s is formed in a groove shape cut out from the outside. When injecting into a patient, it is necessary to remove the injection needle cover 5 2, but until then, the precautionary statement 2 2 b of the inner lid piece 2 2 or the precautionary note 1 3 t of part of the standing piece 13 s 1 3 x force S is noticeable, so it is possible to call attention to the injection in the syringe 50 until immediately before the injection. For example, even if the preparation is adjusted and the injection is transferred to the syringe 50, the precautionary statement “Prohibition and intrathecal injection” must be given just before administration to the patient in the hospital room (just before removing the injection needle cover 52). Comes with 2 b, 1 3 x.

A part of the individual packaging box 10 that would otherwise be discarded can be used to alert the injection in the syringe 50 by using a part 22 of 20; 20 s, 13 t, which requires special components. No resources can be used effectively. In addition, it is only necessary to devise the design of the individual packaging box 10, and the injections can be individually packaged in the same process as the conventional one using the conventional grass-making equipment, resulting in a change in the production line and an increase in cost. Absent.

Note that the present invention is not limited to the above embodiment, and can be implemented in various other modes.

For example, cut off the inner lid piece 2 2; 20 s to the needle mounting part 50 a of the syringe 50, the outer cylinder part 50 b, the collar part 50 c, a certain piston rod 50 d, etc. You can also attach it to In addition, the upper and lower parts of the inner lid pieces 20 and 22; 20 s and 22 s are reversed so that the inner lid piece 2 2 and 20 s which is torn off can be seen first when opened. Les ,. Further, either of the pair of inner lid pieces 20 and 22; 20 s and 22 s may be torn off, and both inner lid pieces 20 and 22; 20 s and 22 s You may be able to remove it.

Claims

The scope of the claims

1. An indicator piece (22; 20 s, 13 t) that can be attached to the syringe is formed integrally in a separable manner. b; 13 x) is displayed, an individual packaging box for injection.

2. Insertion holes (22a; 20k, 20x, 20y, 20z) through which the needle cover (52) of the syringe is inserted are formed in the display pieces (22; 20s, 13t). The individual injection box according to claim 1, characterized in that:

3. The individual injection box according to claim 2, wherein the insertion hole (22a; 20k) is circular.

4. The individual injection box according to claim 2, wherein the through holes (20x, 20y) are polygonal.

5. The individual injection box according to claim 2, wherein the insertion hole (20z) has a star shape.

6. The display piece (22) is formed on the inner lid piece (22) on the opening side of the individual packaging box (10), and the connecting portion of the display piece (22) has a score line (22c). The individual injection box according to claim 1, wherein the injection box is formed.

7. Form the display piece (22) on one (22) of the pair of inner lid pieces (20, 22) on the opening side of the packaging box (10), and place the display piece (22) on the other (20). 7. The individual injection box according to claim 6, further comprising a pictorial indication (20a) illustrating a method of attaching the) to the syringe.

8. An injection stored in the individual injection box (10; 10k, 10x, 10y, 10z) according to claims 1 to 7.

9. Intrathecal injection is prohibited on the above display piece (22; 20 s, 13 t) of the above injection box (10; 10 k, 10 X, 10 y, 10 z) Precautionary Statement (22b; 1)

9. The injection for intravenous injection according to claim 8, wherein 3x) is displayed.