WO2000044415A1 - Regulateur de pression permettant d'effectuer un drainage assiste par depression - Google Patents

Regulateur de pression permettant d'effectuer un drainage assiste par depression Download PDF

Info

Publication number
WO2000044415A1
WO2000044415A1 PCT/DK2000/000034 DK0000034W WO0044415A1 WO 2000044415 A1 WO2000044415 A1 WO 2000044415A1 DK 0000034 W DK0000034 W DK 0000034W WO 0044415 A1 WO0044415 A1 WO 0044415A1
Authority
WO
WIPO (PCT)
Prior art keywords
vacuum
pressure regulator
pressure
reservoir
valve
Prior art date
Application number
PCT/DK2000/000034
Other languages
English (en)
Inventor
Jens Mikkelsen
Original Assignee
Polystan Holding A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Polystan Holding A/S filed Critical Polystan Holding A/S
Priority to AU22784/00A priority Critical patent/AU2278400A/en
Publication of WO2000044415A1 publication Critical patent/WO2000044415A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3623—Means for actively controlling temperature of blood
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3666—Cardiac or cardiopulmonary bypass, e.g. heart-lung machines
    • A61M1/3667—Cardiac or cardiopulmonary bypass, e.g. heart-lung machines with assisted venous return
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71—Suction drainage systems
    • A61M1/74—Suction control
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71—Suction drainage systems
    • A61M1/74—Suction control
    • A61M1/743—Suction control by changing the cross-section of the line, e.g. flow regulating valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1698—Blood oxygenators with or without heat-exchangers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
    • A61M1/3621—Extra-corporeal blood circuits
    • A61M1/3627—Degassing devices; Buffer reservoirs; Drip chambers; Blood filters

Definitions

  • the present invention relates to a pressure regulator for vacuum assisted drainage of blood from a patient during a surgical operation, during which the blood drained is transferred to a reservoir in which a vacuum is produced by means of the pressure regulator, the pressure regulator being adapted to reduce a vacuum from a vacuum source to an underpressure with an adjustable set value in the range from 0-300 mm Hg, preferably from 0-100 mm Hg.
  • This type of drainage is typically intended for venous drainage, but may also be used for drainage from the operation field or other vessels.
  • the patient's blood is drained from Vena Cava Superior (VS) , Vena Cava Inferior (VCI) or the atrium by means of one or more venous catheters to a reservoir/filter system suitable therefor, before the blood is taken back to the patient's own arteries by means of a peristaltic pump via an oxygenator.
  • the driving force in the drainage derives partly from the gravitation of the liquid column connecting the patient with the reservoir, partly the possible overpressure in the vessels. It has therefore been common practice to place the reservoir in a low position and to use tubes of a fairly big cross section to obtain a satisfactory drainage.
  • Regulators are known for producing a vacuum in a reservoir of the type used in heart surgical treatment. This regulator produces a vacuum corresponding to a predetermined set value, which under normal circumstances will increase the drainage .
  • the regulator does not, however, provide an optimal safety against complications under special conditions which may occur during an operation.
  • the object of the invention is to establish a pressure regulator which is easier to control during an operation and which thus increases the safety of the patient, in particular in case of complicated operations. This object is met by the pressure regulator according to the invention, which pressure regulator is characterized by the subject matter of the characterizing clause of claim 1.
  • the blood level in the reservoir will raise and fall as a consequence of varying arterial blood flow and varying return flow.
  • the reservoir with vacuum assisted drainage is completely closed towards the ambient air.
  • the pressure regulator is able to reduce an underpressure which exceeds the predetermined value.
  • the pressure regulator according to the invention is a separate unit which by means of a tube or in another manner is connected with the reservoir and which comprises a component group consisting of a pressure registering means positioned in the connection to the reservoir and valve means positioned in the connection to the vacuum source and valve means in connection with the ambient air.
  • the pressure regulator as an independent, complete unit, which by means of a single tube is connected with the reservoir, the arrangement procedure prior to the operation is simplified, and the control thereof is simplified in relation to the control of frequently used operation equipment which comprises tubes for the individual functions and which are occluded by means of forceps or the like.
  • the pressure regulator may be designed as an electronic regulator as stated in claim 3.
  • the preferred embodiment is, however, mechanical and comprises the measures stated in claim 4.
  • the use of a balanced slide valve of the type which is commonly used in hydraulic installations ensures a wide regulation range and a high sensitivity on account of the outbalanced pressure forces in the varying pressure levels.
  • the design moreover contributes to making the regulation insensitive to fluctuations in the pressure of the vacuum source .
  • the regulation of the set value takes place as stated in claim 5 by means of a control handle which is adapted to displace the counter-stop of a spring outbalancing the pressure difference on the two sides of the membrane.
  • the regulation may in practice take place by means of a thread such that the control handle may be turned several revolutions between the two distal positions.
  • the slide valve is a cylindrical slide valve.
  • the pressure regulator further comprises safety valves as stated in claim 7.
  • These safety valves are preset on values which would otherwise represent a life-threatening condition for the patient, should they be transgressed. These valves will in most cases represent a supplement to other possibilities which surgeons establish or will not bar themselves from using, but contribute, by their presence, to simplifying the setup of the equipment prior to a surgical operation.
  • FIG. 1 shows a strongly schematic arrangement for a heart surgical operation and with a diagram of the pressure regulator according to the invention inserted in chart form
  • Fig. 2 is a sectional view through an embodiment of the pressure regulator according to the invention.
  • Fig. 3 is a diagrammatical view of an electronic embodiment of a pressure regulator according to the invention.
  • a patient is indicated by 1, said patient undergoing a heart operation, in which the heart function is taken over via a circuit outside the patient.
  • the blood is drained to a reservoir 2 by means of a tube connection 3.
  • the blood is filtered by means of a tube connection 3.
  • the blood is normally filtered in an exterior filter 4.
  • a blood level 5 adjusts, and from the reservoir blood is via a pump 6 introduced through an oxygenator 7 provided with means for controlling the temperature of the blood back to the arterial circuit of the patient through a tube 8.
  • a driving force in the drainage of blood through the tube 3 derives from a height difference h between the patient 1 and the reservoir 2.
  • this height difference is, however, not suffi- cient for ensuring a stable and sufficient blood flow. It is therefore common practice by means of a vacuum in the reservoir 2 to establish a supplement to the effect of the height difference. In such a vacuum unassisted drainage, care is taken that the reservoir is closely sealed in respect of the surroundings, i.e. the connections to the surroundings are kept capped.
  • the vacuum used in such operations is normally kept at a level of 0-100 mm Hg to avoid damage to the blood cells, release of dissolved gases forming micro bubbles, which are most damaging to the patient, and to avoid a collapse of the vein in the area in which the tube is inserted.
  • the vacuum is established on basis of the installation which is normally available in operation rooms, i.e. by means of a controllable pressure reducing valve. For reduction of the pressure in the general installation, accurately functioning pressure reducing valves are available. These valves do not, however, eliminate the risk that the vacuum, on account of falling blood level in the reservoir 2, may be increased beyond the level preset.
  • the invention provides a pressure regulator which eliminates this risk, the regulator establishing a 2 -way regulation maintaining the predetermined vacuum irrespective of fluctuations in the liquid level.
  • This function is in practice an essential help for the operator which is to maintain the external and internal blood circuit of the patient stable during a surgical operation.
  • Fig. 1 shows a diagram of a pressure regulator according to the invention.
  • the pressure regulator is built into a housing 9 and comprises a connection branch 10 in connection with the reservoir 2.
  • the connection branch 10 is connected with a vacuum switch- off setting the regulator in function. From the switch- off 11 a main duct 12 leads to the various components of the regulator.
  • a branching leads to a manometer displaying the preset vacuum.
  • a second branch leads to safety valves 14 and 15 adapted to ensure that the vacuum does not transgress a predetermined limit value and that a superpressure does not occur in the reser- voir 2.
  • the function of the reduction valve is performed by a slide valve 16 controlled by a membrane 17 which on one hand is influenced by the preset vacuum via the tube and on the other hand by the ambient pressure.
  • Fig. 2 is a sectional view of a practical embodiment of the pressure regulator according to the invention.
  • references identical with those in Fig. 1 have been used as far as possible.
  • the necessary connection ducts are substantially bored or milled in two plane component blocks 24 and 25, between which a membrane serving as a packing has been clamped.
  • the design makes it simple to make a periodical check of the functions of the regulator and to exchange the mem- brane, which at the same time serves as a sealing in the safety valves 14, 15 and between the component blocks .
  • the diagram according to Fig. 3 is a schematic veiw of the regulator according to the invention.
  • the connection 28 to the reservoir 2 is provided with a branching for a pressure transducer 29 emitting a signal to a signal regulator 30 via an amplifier 30.
  • the signal regulator emits a control current to two magnet valves 32 and 33 which are connected with the ambient air and a vacuum source, respectively.
  • the electronic design depends on a current supply, but is basically equivalent to the design according to Figs 1 and 2.
  • the pressure regulation may according to Fig. 3 be further developed with electronic monitoring or be adapted to receive additional control signals from external control systems which may for example be a part of the monitoring of the patient's condition.

Landscapes

  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • External Artificial Organs (AREA)

Abstract

L'invention concerne un régulateur de pression permettant d'effectuer sur un sujet (1) un drainage sanguin assisté par dépression pendant une opération chirurgicale, pendant laquelle le sang drainé est transféré dans un réservoir (2) dans lequel on crée un vide à l'aide du régulateur de pression. Ce dernier est conçu pour amener un vide provenant d'une source de vide à une pression réduite à l'aide d'une valeur fixée réglable comprise entre 0 et 300 mm Hg, de préférence entre 0 et 100 mm Hg. Afin d'éliminer le risque qu'un abaissement du niveau de liquide dans le réservoir provoque une augmentation indésirable du vide et afin de faire fonctionner le régulateur de pression comme une unité, ce qui simplifie les préparatifs en vue d'une intervention chirurgicale, le régulateur de pression est conçu pour augmenter le vide si celui-ci se trouve en-dessous de la valeur fixée et pour réduire le vide, lorsque la valeur fixée est dépassée.
PCT/DK2000/000034 1999-01-29 2000-01-27 Regulateur de pression permettant d'effectuer un drainage assiste par depression WO2000044415A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU22784/00A AU2278400A (en) 1999-01-29 2000-01-27 A pressure regulator for vacuum assisted drainage

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199900119 1999-01-29
DK199900119A DK199900119A (da) 1999-01-29 1999-01-29 Trykregulator til vakuumassisteret drænage

Publications (1)

Publication Number Publication Date
WO2000044415A1 true WO2000044415A1 (fr) 2000-08-03

Family

ID=8089962

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DK2000/000034 WO2000044415A1 (fr) 1999-01-29 2000-01-27 Regulateur de pression permettant d'effectuer un drainage assiste par depression

Country Status (3)

Country Link
AU (1) AU2278400A (fr)
DK (1) DK199900119A (fr)
WO (1) WO2000044415A1 (fr)

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004035111A3 (fr) * 2002-10-16 2004-06-24 Alcon Inc Essai de capteur de pression dans une cassette chirurgicale
WO2004035112A3 (fr) * 2002-10-16 2004-07-01 Alcon Inc Detection de pression amelioree dans une console chirurgicale
DE102009026592A1 (de) 2009-05-29 2010-12-02 Sorin Group Deutschland Gmbh Vorrichtung zur Festlegung des venösen Zuflusses zu einem Blutreservoir eines extrakorporalen Blutkreislaufs
US8500673B2 (en) 2010-04-20 2013-08-06 Sorin Group Italia S.R.L. Blood reservoir with level sensor
US8506513B2 (en) 2010-04-20 2013-08-13 Sorin Group Italia S.R.L. Blood reservoir with ultrasonic volume sensor
US9011769B2 (en) 2011-07-12 2015-04-21 Sorin Group Italia S.R.L. Dual chamber blood reservoir
US9452250B2 (en) 2009-06-25 2016-09-27 Sorin Group Deutschland Gmbh Device for pumping blood in an extracorporeal circuit
WO2019068338A1 (fr) * 2017-10-06 2019-04-11 Livanova Deutschland Gmbh Contrôle de la contamination et de la condensation d'un régulateur vavd
US10458833B2 (en) 2014-05-16 2019-10-29 Sorin Group Italia S.R.L. Blood reservoir with fluid volume measurement based on pressure sensor
WO2020259837A1 (fr) 2019-06-27 2020-12-30 Livanova Deutschland Gmbh Dispositif pour établir automatiquement un afflux veineux vers un réservoir de sang d'un système de circulation de sang extracorporel

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2777337A (en) * 1952-08-15 1957-01-15 Clifford T Hultin Power transmission

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4372336A (en) * 1980-06-17 1983-02-08 Sherwood Medical Industries, Inc. Chest drainage unit
US4487334A (en) * 1980-08-06 1984-12-11 Werding Winfried J Thrust control means mountable in a pressurized container
US5261897A (en) * 1990-12-04 1993-11-16 Bioresearch, Inc. Portable suction system
US5520652A (en) * 1992-11-04 1996-05-28 Medical Instrument Development Laboratories, Inc. Methods and apparatus for control of vacuum and pressure for surgical procedures
US6017493A (en) * 1997-09-26 2000-01-25 Baxter International Inc. Vacuum-assisted venous drainage reservoir for CPB systems

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4372336A (en) * 1980-06-17 1983-02-08 Sherwood Medical Industries, Inc. Chest drainage unit
US4487334A (en) * 1980-08-06 1984-12-11 Werding Winfried J Thrust control means mountable in a pressurized container
US5261897A (en) * 1990-12-04 1993-11-16 Bioresearch, Inc. Portable suction system
US5520652A (en) * 1992-11-04 1996-05-28 Medical Instrument Development Laboratories, Inc. Methods and apparatus for control of vacuum and pressure for surgical procedures
US6017493A (en) * 1997-09-26 2000-01-25 Baxter International Inc. Vacuum-assisted venous drainage reservoir for CPB systems

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004035112A3 (fr) * 2002-10-16 2004-07-01 Alcon Inc Detection de pression amelioree dans une console chirurgicale
US6868720B2 (en) 2002-10-16 2005-03-22 Alcon, Inc. Testing of pressure sensor in surgical cassette
US6955073B2 (en) 2002-10-16 2005-10-18 Alcon, Inc. Pressure sensing in surgical console
WO2004035111A3 (fr) * 2002-10-16 2004-06-24 Alcon Inc Essai de capteur de pression dans une cassette chirurgicale
DE102009026592A1 (de) 2009-05-29 2010-12-02 Sorin Group Deutschland Gmbh Vorrichtung zur Festlegung des venösen Zuflusses zu einem Blutreservoir eines extrakorporalen Blutkreislaufs
US11844892B2 (en) 2009-05-29 2023-12-19 Livanova Deutschland Gmbh Device for establishing the venous inflow to a blood reservoir of an extracorporeal blood circulation system
EP2842584A1 (fr) 2009-05-29 2015-03-04 Sorin Group Deutschland GmbH Dispositif de détermination de l'afflux sanguin dans un réservoir de sang d'un circuit sanguin extra corporel
US11229729B2 (en) 2009-05-29 2022-01-25 Livanova Deutschland Gmbh Device for establishing the venous inflow to a blood reservoir of an extracorporeal blood circulation system
CN105169508A (zh) * 2009-05-29 2015-12-23 索林集团德国有限责任公司 用于确定至体外血液循环的血液贮存器的静脉入流的装置
US9452250B2 (en) 2009-06-25 2016-09-27 Sorin Group Deutschland Gmbh Device for pumping blood in an extracorporeal circuit
US8500673B2 (en) 2010-04-20 2013-08-06 Sorin Group Italia S.R.L. Blood reservoir with level sensor
US8506513B2 (en) 2010-04-20 2013-08-13 Sorin Group Italia S.R.L. Blood reservoir with ultrasonic volume sensor
US10213541B2 (en) 2011-07-12 2019-02-26 Sorin Group Italia S.R.L. Dual chamber blood reservoir
US9011769B2 (en) 2011-07-12 2015-04-21 Sorin Group Italia S.R.L. Dual chamber blood reservoir
US11389580B2 (en) 2011-07-12 2022-07-19 Sorin Group Italia S.R.L. Dual chamber blood reservoir
US10458833B2 (en) 2014-05-16 2019-10-29 Sorin Group Italia S.R.L. Blood reservoir with fluid volume measurement based on pressure sensor
WO2019068338A1 (fr) * 2017-10-06 2019-04-11 Livanova Deutschland Gmbh Contrôle de la contamination et de la condensation d'un régulateur vavd
JP2020535943A (ja) * 2017-10-06 2020-12-10 リヴァノヴァ・ドイチュラント・ゲーエムベーハー Ｖａｖｄ調圧器の汚染及び結露の制御
US11590274B2 (en) 2017-10-06 2023-02-28 Livanova Deutschland Gmbh VAVD regulator contamination and condensation control
US11819603B2 (en) 2017-10-06 2023-11-21 Livanova Deutschland Gmbh VAVD regulator contamination and condensation control
US12109351B2 (en) 2017-10-06 2024-10-08 Livanova Deutschland Gmbh VAVD regulator contamination and condensation control
WO2020259837A1 (fr) 2019-06-27 2020-12-30 Livanova Deutschland Gmbh Dispositif pour établir automatiquement un afflux veineux vers un réservoir de sang d'un système de circulation de sang extracorporel

Also Published As

Publication number Publication date
DK199900119A (da) 2000-09-04
AU2278400A (en) 2000-08-18

Similar Documents

Publication Publication Date Title
US4610656A (en) Fully portable semi-automatic mechanical heart-lung substitution system and method
US8992408B2 (en) Percutaneous right ventricular assist apparatus and method
US5158529A (en) Pumping device for operating an intra-aortic balloon
US4604089A (en) Pressure regulated irrigation system for arthroscopy
US6315751B1 (en) Cardiopulmonary bypass system using vacuum assisted venous drainage
US6537495B1 (en) Vacuum-assisted venous drainage system with rigid housing and flexible reservoir
US4650462A (en) Irrigation system
WO2000044415A1 (fr) Regulateur de pression permettant d'effectuer un drainage assiste par depression
JP4051812B2 (ja) 制御機能を備えた体外循環装置
AU5583098A (en) Device and method for preparation of substitution solution
WO2005084304A2 (fr) Tube de drainage de blessure chirurgicale equipe de protections de controle de flux
EP0185658B1 (fr) Systeme de curage pour la capsule de l'articulation du genou
CH699261B1 (de) Extrakorporales Zirkulationssystem, insbesondere für einen multifunktionalen Herz-Lungen-Bypass und zur Minimierung von Luftembolien.
WO2021005133A3 (fr) Commande pour pompes à sang non occlusives
US5192265A (en) Adjustable-resistance anti-siphon device
EP1003575A1 (fr) Systeme et procede d'operation la moins effractive possible a drainage veineux a depression
US20080009679A1 (en) System, method and apparatus for regulating vacuum supplied to surgical tools
Davila et al. Venoarterial air embolus: a complication of vacuum-assisted venous drainage
WO2005009289A3 (fr) Appareil et procedes pour commander d'administration de liquides intraveineux
US8900177B2 (en) Self adjusting venous equalizing graft
US4196729A (en) Device for perfusing a heart with blood supplied at constant pressure
JP4052333B2 (ja) 制御機能を備えた体外循環装置
CN213312288U (zh) 一种多用途小型化微创体外循环管路
CN107469162B (zh) 一种高精度静脉引流装置
US8070668B2 (en) Controlled inflation of a pneumatic L-VAD

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AE AL AM AT AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ CZ DE DE DK DK DM EE EE ES FI FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase