WO2000033789A3 - Inhalation powders - Google Patents

Inhalation powders Download PDF

Info

Publication number
WO2000033789A3
WO2000033789A3 PCT/US1999/028608 US9928608W WO0033789A3 WO 2000033789 A3 WO2000033789 A3 WO 2000033789A3 US 9928608 W US9928608 W US 9928608W WO 0033789 A3 WO0033789 A3 WO 0033789A3
Authority
WO
WIPO (PCT)
Prior art keywords
fraction
particle size
inhalation powders
present
excipient powder
Prior art date
Application number
PCT/US1999/028608
Other languages
French (fr)
Other versions
WO2000033789A2 (en
Inventor
Jonathan Kenneth Embleton
Original Assignee
R P Scherer Inc
Jonathan Kenneth Embleton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by R P Scherer Inc, Jonathan Kenneth Embleton filed Critical R P Scherer Inc
Priority to AU20383/00A priority Critical patent/AU2038300A/en
Publication of WO2000033789A2 publication Critical patent/WO2000033789A2/en
Publication of WO2000033789A3 publication Critical patent/WO2000033789A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pulmonology (AREA)
  • Chemical & Material Sciences (AREA)
  • Otolaryngology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

The present invention relates to inhalable drugs in particulate form. More specifically, the present invention is directed to an excipient powder that comprises a coarse first fraction having a particle size of 10νm, a fine second fraction having a particle size of no more than 10νm and a third fraction consisting of ternary agents. The excipient powder has been found to be beneficial in the administration of phamarceuticals to the pulmonary system.
PCT/US1999/028608 1998-12-04 1999-12-03 Inhalation powders WO2000033789A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU20383/00A AU2038300A (en) 1998-12-04 1999-12-03 Inhalation powders

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9826783.4 1998-12-04
GBGB9826783.4A GB9826783D0 (en) 1998-12-04 1998-12-04 Inhalation powders

Publications (2)

Publication Number Publication Date
WO2000033789A2 WO2000033789A2 (en) 2000-06-15
WO2000033789A3 true WO2000033789A3 (en) 2000-09-14

Family

ID=10843720

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/028608 WO2000033789A2 (en) 1998-12-04 1999-12-03 Inhalation powders

Country Status (3)

Country Link
AU (1) AU2038300A (en)
GB (1) GB9826783D0 (en)
WO (1) WO2000033789A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9511467B2 (en) 2013-06-10 2016-12-06 Ford Global Technologies, Llc Cylindrical surface profile cutting tool and process

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITMI991582A1 (en) 1999-07-16 2001-01-16 Chiesi Farma Spa DUST CONSTITUTED FROM PARTICLES HAVING THE PERFECTLY SMOOTH SURFACE FOR USE AS VEHICLES FOR THE PREPARATION OF INALA MIXTURES
GB0009469D0 (en) 2000-04-17 2000-06-07 Vectura Ltd Improvements in or relating to formalities for use in inhaler devices
PE20011227A1 (en) 2000-04-17 2002-01-07 Chiesi Farma Spa PHARMACEUTICAL FORMULATIONS FOR DRY POWDER INHALERS IN THE FORM OF HARD AGGLOMERATES
GB0014851D0 (en) * 2000-06-16 2000-08-09 Glaxo Group Ltd Novel pharmaceutical formulation
JP5698423B2 (en) * 2000-06-27 2015-04-08 ベクトゥラ・リミテッド Process for the production of particles for use in pharmaceutical compositions
IL153705A0 (en) 2000-06-27 2003-07-06 Vectura Ltd Method of making particles for use in a pharmaceutical composition
DE60140268D1 (en) 2000-11-30 2009-12-03 Vectura Ltd PARTICLES FOR USE IN A PHARMACEUTICAL COMPOSITION
ES2708961T3 (en) 2000-11-30 2019-04-12 Vectura Ltd Pharmaceutical compositions for inhalation
KR20070119631A (en) 2005-02-10 2007-12-20 글락소 그룹 리미티드 Processes for making lactose utilizing pre-classification techniques and pharmaceutical formulations formed therefrom
GB0613161D0 (en) 2006-06-30 2006-08-09 Novartis Ag Organic Compounds
US8726874B2 (en) 2012-05-01 2014-05-20 Ford Global Technologies, Llc Cylinder bore with selective surface treatment and method of making the same
WO2014007766A1 (en) * 2012-07-05 2014-01-09 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Dry powder inhalers comprising a carrier other than lactose
US10105316B2 (en) 2012-07-05 2018-10-23 Arven llac Sanayi Ve Ticaret A.S. Inhalation compositions comprising muscarinic receptor antagonist
GB201305825D0 (en) 2013-03-28 2013-05-15 Vectura Ltd New use
CN104274427A (en) * 2013-07-03 2015-01-14 陆克塞纳医药公司 Novel aerosol formulations of granisetron and uses thereof
CN104274426A (en) * 2013-07-03 2015-01-14 陆克塞纳医药公司 Novel aerosol formulations of ondansetron and uses thereof
WO2016005434A1 (en) * 2014-07-09 2016-01-14 Arven Ilac Sanayi Ve Ticaret A.S. Novel process for the preparation of dry powder formulations
KR102462058B1 (en) * 2014-10-08 2022-11-01 잠본쏘시에떼퍼아찌오니 Composition comprising at least one dry powder obtained by spray drying to increase the stability of the formulation
MY191295A (en) * 2014-10-08 2022-06-14 Zambon Spa Pharmaceutical composition containing budesonide and formoterol
CN106692116A (en) * 2015-11-15 2017-05-24 复旦大学 Capsule-type inhalation aerosol powder containing isoforskolin
JP2022549445A (en) 2019-09-24 2022-11-25 キエシ・フアルマチエウテイチ・ソチエタ・ペル・アチオニ Novel carrier particles for dry powder formulations for inhalation
KR102488719B1 (en) * 2020-12-03 2023-01-13 충북대학교 산학협력단 Dry powder inhalation formulation containing selexipag and manufacturing method thereof

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5747445A (en) * 1993-06-24 1998-05-05 Astra Aktiebolag Therapeutic preparation for inhalation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9511467B2 (en) 2013-06-10 2016-12-06 Ford Global Technologies, Llc Cylindrical surface profile cutting tool and process

Also Published As

Publication number Publication date
AU2038300A (en) 2000-06-26
GB9826783D0 (en) 1999-01-27
WO2000033789A2 (en) 2000-06-15

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