WO2000032209A3 - Submucosa modulation of mammalian immune response - Google Patents

Submucosa modulation of mammalian immune response Download PDF

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Publication number
WO2000032209A3
WO2000032209A3 PCT/US1999/028302 US9928302W WO0032209A3 WO 2000032209 A3 WO2000032209 A3 WO 2000032209A3 US 9928302 W US9928302 W US 9928302W WO 0032209 A3 WO0032209 A3 WO 0032209A3
Authority
WO
WIPO (PCT)
Prior art keywords
submucosa
immune response
modulation
mammalian immune
composition
Prior art date
Application number
PCT/US1999/028302
Other languages
French (fr)
Other versions
WO2000032209A2 (en
Inventor
Stephen F Badylak
Timothy B Mcpherson
Dennis Metzger
Original Assignee
Purdue Research Foundation
Medical College Of Ohio At Tol
Stephen F Badylak
Timothy B Mcpherson
Dennis Metzger
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation, Medical College Of Ohio At Tol, Stephen F Badylak, Timothy B Mcpherson, Dennis Metzger filed Critical Purdue Research Foundation
Priority to GB0114323A priority Critical patent/GB2361187A/en
Priority to AU24748/00A priority patent/AU759272B2/en
Priority to CA002352785A priority patent/CA2352785A1/en
Publication of WO2000032209A2 publication Critical patent/WO2000032209A2/en
Publication of WO2000032209A3 publication Critical patent/WO2000032209A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/37—Digestive system
    • A61K35/38—Stomach; Intestine; Goblet cells; Oral mucosa; Saliva
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Nutrition Science (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Biomedical Technology (AREA)
  • Physiology (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A composition and method for locally suppressing the cell mediated immune response of a vertebrate species is described. The method comprises contacting the site in need of immune suppression with a composition comprising vertebrate submucosa.
PCT/US1999/028302 1998-12-01 1999-12-01 Submucosa modulation of mammalian immune response WO2000032209A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
GB0114323A GB2361187A (en) 1998-12-01 1999-12-01 Submucosa modulation of mammalian immune response
AU24748/00A AU759272B2 (en) 1998-12-01 1999-12-01 Submucosa modulation of mammalian immune response
CA002352785A CA2352785A1 (en) 1998-12-01 1999-12-01 Submucosa modulation of mammalian immune response

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11040298P 1998-12-01 1998-12-01
US60/110,402 1998-12-01

Publications (2)

Publication Number Publication Date
WO2000032209A2 WO2000032209A2 (en) 2000-06-08
WO2000032209A3 true WO2000032209A3 (en) 2000-12-28

Family

ID=22332820

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/028302 WO2000032209A2 (en) 1998-12-01 1999-12-01 Submucosa modulation of mammalian immune response

Country Status (4)

Country Link
AU (1) AU759272B2 (en)
CA (1) CA2352785A1 (en)
GB (1) GB2361187A (en)
WO (1) WO2000032209A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10213526B2 (en) 2014-03-21 2019-02-26 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Methods for preparation of a terminally sterilized hydrogel derived from extracellular matrix
WO2018161028A1 (en) 2017-03-02 2018-09-07 University Of Pittsburgh - Of The Commonwealth System Of Higher Education Ecm hydrogel for treating esophageal inflammation
ES2945740T3 (en) 2017-05-05 2023-07-06 Univ Pittsburgh Commonwealth Sys Higher Education Matrix-Bound Vesicles (MBV) Ocular Applications

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990000395A1 (en) * 1988-07-11 1990-01-25 Purdue Research Foundation Tissue graft composition and method
WO1994011008A1 (en) * 1992-11-13 1994-05-26 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft
WO1999012555A1 (en) * 1997-09-11 1999-03-18 Purdue Research Foundation Galactosidase modified submucosal tissue

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1990000395A1 (en) * 1988-07-11 1990-01-25 Purdue Research Foundation Tissue graft composition and method
WO1994011008A1 (en) * 1992-11-13 1994-05-26 Purdue Research Foundation Fluidized intestinal submucosa and its use as an injectable tissue graft
WO1999012555A1 (en) * 1997-09-11 1999-03-18 Purdue Research Foundation Galactosidase modified submucosal tissue

Also Published As

Publication number Publication date
AU759272B2 (en) 2003-04-10
CA2352785A1 (en) 2000-06-08
GB2361187A (en) 2001-10-17
AU2474800A (en) 2000-06-19
GB0114323D0 (en) 2001-08-01
WO2000032209A2 (en) 2000-06-08

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