WO2000026350A3 - Coenzyme a-utilizing enzymes - Google Patents

Coenzyme a-utilizing enzymes Download PDF

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Publication number
WO2000026350A3
WO2000026350A3 PCT/US1999/025820 US9925820W WO0026350A3 WO 2000026350 A3 WO2000026350 A3 WO 2000026350A3 US 9925820 W US9925820 W US 9925820W WO 0026350 A3 WO0026350 A3 WO 0026350A3
Authority
WO
WIPO (PCT)
Prior art keywords
coenzyme
coaen
utilizing enzymes
provides
expression
Prior art date
Application number
PCT/US1999/025820
Other languages
French (fr)
Other versions
WO2000026350A2 (en
Inventor
Y Tom Tang
Neil C Corley
Karl J Guegler
Gina A Gorgone
Yalda Azimzai
Matthew R Kaser
Henry Yue
Original Assignee
Incyte Pharma Inc
Y Tom Tang
Neil C Corley
Karl J Guegler
Gina A Gorgone
Yalda Azimzai
Matthew R Kaser
Henry Yue
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Incyte Pharma Inc, Y Tom Tang, Neil C Corley, Karl J Guegler, Gina A Gorgone, Yalda Azimzai, Matthew R Kaser, Henry Yue filed Critical Incyte Pharma Inc
Priority to JP2000579722A priority Critical patent/JP2004510401A/en
Priority to AU12424/00A priority patent/AU1242400A/en
Priority to EP99971449A priority patent/EP1127111A2/en
Priority to CA002349586A priority patent/CA2349586A1/en
Publication of WO2000026350A2 publication Critical patent/WO2000026350A2/en
Publication of WO2000026350A3 publication Critical patent/WO2000026350A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

The invention provides human coenzyme A-utilizing enzymes (CoAEN) and polynucleotides which identify and encode CoAEN. The invention also provides expression vectors, host cells, antibodies, agonists and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with expression of CoAEN.
PCT/US1999/025820 1998-11-03 1999-11-03 Coenzyme a-utilizing enzymes WO2000026350A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000579722A JP2004510401A (en) 1998-11-03 1999-11-03 Enzyme utilizing coenzyme A
AU12424/00A AU1242400A (en) 1998-11-03 1999-11-03 Coenzyme a-utilizing enzymes
EP99971449A EP1127111A2 (en) 1998-11-03 1999-11-03 Coenzyme a-utilizing enzymes
CA002349586A CA2349586A1 (en) 1998-11-03 1999-11-03 Coenzyme a-utilizing enzymes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18521798A 1998-11-03 1998-11-03
US09/185,217 1998-11-03

Publications (2)

Publication Number Publication Date
WO2000026350A2 WO2000026350A2 (en) 2000-05-11
WO2000026350A3 true WO2000026350A3 (en) 2000-12-07

Family

ID=22680088

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/025820 WO2000026350A2 (en) 1998-11-03 1999-11-03 Coenzyme a-utilizing enzymes

Country Status (4)

Country Link
EP (1) EP1127111A2 (en)
AU (1) AU1242400A (en)
CA (1) CA2349586A1 (en)
WO (1) WO2000026350A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001066759A2 (en) * 2000-03-07 2001-09-13 Millennium Pharmaceuticals, Inc. 26886, a novel carnitine acyltransferase family member and uses therefor
WO2003076565A2 (en) * 2001-09-17 2003-09-18 Millennium Pharmaceuticals, Inc. Methods of using 46828, a human acyl-coa synthetase

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994009126A2 (en) * 1992-10-14 1994-04-28 Trustees Of Dartmouth College Acyl coenzyme a: cholesterol acyltransferase (acat)
US5635616A (en) * 1995-06-02 1997-06-03 Human Genome Sciences, Inc. Human oxalyl-CoA decarboxylase

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994009126A2 (en) * 1992-10-14 1994-04-28 Trustees Of Dartmouth College Acyl coenzyme a: cholesterol acyltransferase (acat)
US5635616A (en) * 1995-06-02 1997-06-03 Human Genome Sciences, Inc. Human oxalyl-CoA decarboxylase

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
J WEST ET AL: "Cloning and expression of two human lysophosphatidic acid acyltransferase cDNAs that enhance cytokine induced signaling responses in cells", DNA AND CELL BIOLOGY,US,NEW YORK, NY, vol. 16, no. 6, 1 June 1997 (1997-06-01), pages 691 - 701, XP002082603, ISSN: 1044-5498 *
STAMPS, A. ET AL.: "A human cDNA sequence with homology to non-mammalian lysophosphatidic acid acyltransferases", BIOCHEMICAL JOURNAL, vol. 326, 1 September 1997 (1997-09-01), pages 455 - 461, XP000916280 *

Also Published As

Publication number Publication date
AU1242400A (en) 2000-05-22
WO2000026350A2 (en) 2000-05-11
CA2349586A1 (en) 2000-05-11
EP1127111A2 (en) 2001-08-29

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