WO2000024869A3 - Methodes de modulation de fusion cellulaire - Google Patents
Methodes de modulation de fusion cellulaire Download PDFInfo
- Publication number
- WO2000024869A3 WO2000024869A3 PCT/US1999/024838 US9924838W WO0024869A3 WO 2000024869 A3 WO2000024869 A3 WO 2000024869A3 US 9924838 W US9924838 W US 9924838W WO 0024869 A3 WO0024869 A3 WO 0024869A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cell fusion
- methods
- fusion
- mfr
- modulation
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/728—Hyaluronic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/737—Sulfated polysaccharides, e.g. chondroitin sulfate, dermatan sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/177—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/465—Hydrolases (3) acting on ester bonds (3.1), e.g. lipases, ribonucleases
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5023—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
- G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
- G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
- G01N33/5047—Cells of the immune system
- G01N33/5055—Cells of the immune system involving macrophages
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56966—Animal cells
- G01N33/56972—White blood cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
- G01N2333/70585—CD44
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biomedical Technology (AREA)
- Cell Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Analytical Chemistry (AREA)
- Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Zoology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU12242/00A AU1224200A (en) | 1998-10-23 | 1999-10-22 | Methods for modulating cell fusion |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15738798P | 1998-10-23 | 1998-10-23 | |
US60/157,387 | 1998-10-23 |
Publications (3)
Publication Number | Publication Date |
---|---|
WO2000024869A2 WO2000024869A2 (fr) | 2000-05-04 |
WO2000024869A9 WO2000024869A9 (fr) | 2005-02-10 |
WO2000024869A3 true WO2000024869A3 (fr) | 2007-08-23 |
Family
ID=22563509
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/024838 WO2000024869A2 (fr) | 1998-10-23 | 1999-10-22 | Methodes de modulation de fusion cellulaire |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU1224200A (fr) |
WO (1) | WO2000024869A2 (fr) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9930706D0 (en) * | 1999-12-24 | 2000-02-16 | Medical Res Council | Composition for inhibiting macrophage activity |
PL3307065T3 (pl) * | 2015-06-11 | 2024-02-19 | The Board Of Trustees Of The University Of Illinois | Komórki chimeryczne związane z dystrofią mięśniową i sposób leczenia dystrofii mięśniowych |
JP7461741B2 (ja) | 2016-06-20 | 2024-04-04 | カイマブ・リミテッド | 抗pd-l1およびil-2サイトカイン |
SG11202000658PA (en) | 2017-07-26 | 2020-02-27 | Forty Seven Inc | Anti-sirp-alpha antibodies and related methods |
CN108567973B (zh) * | 2017-10-17 | 2021-03-19 | 中国科学院深圳先进技术研究院 | 一种胎盘样硫酸软骨素a免疫组合物及应用 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5804594A (en) * | 1997-01-22 | 1998-09-08 | Murad; Howard | Pharmaceutical compositions and methods for improving wrinkles and other skin conditions |
-
1999
- 1999-10-22 AU AU12242/00A patent/AU1224200A/en not_active Abandoned
- 1999-10-22 WO PCT/US1999/024838 patent/WO2000024869A2/fr active Application Filing
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5804594A (en) * | 1997-01-22 | 1998-09-08 | Murad; Howard | Pharmaceutical compositions and methods for improving wrinkles and other skin conditions |
Non-Patent Citations (5)
Title |
---|
KLUEG K M, PARODY T R, MUSKAVITCH M A T, AMERICAN SOCIETY FOR CELL BIOLOGY ANNUAL MEETING., XX, XX, 1 December 1997 (1997-12-01), XX, pages 413 + 01, XP002926946 * |
SAGINARIO ET AL.: "Identification of an Inducible Surface Molecule Specific to Fusing Macrophages", PROC. NATL. ACAD. SCI. USA,, vol. 92, December 1995 (1995-12-01), pages 12210 - 12214, XP002926947 * |
SAGINARIO ET AL.: "MFR, a Putative Receptor Mediating the Fusion of Macrophages", MOLECULAR AND CELLULAR BIOLOGY,, vol. 18, no. 11, November 1998 (1998-11-01), pages 6213 - 6223, XP002926948 * |
STERLING ET AL.: "CD44 Occupancy Prevents Macrophage Multinucleation", THE JOURNAL OF CELL BIOLOGY,, vol. 143, no. 3, November 1998 (1998-11-01), pages 837 - 847, XP002926949 * |
STERLING H, SAGINARIO C, VIGNERY A: "CD44 OCCUPANCY PREVENTS THE FUSION OF MACROPHAGES", AMERICAN SOCIETY FOR CELL BIOLOGY ANNUAL MEETING., XX, XX, vol. 08, 1 December 1997 (1997-12-01), XX, pages 413 + 01, XP002926945 * |
Also Published As
Publication number | Publication date |
---|---|
WO2000024869A2 (fr) | 2000-05-04 |
WO2000024869A9 (fr) | 2005-02-10 |
AU1224200A (en) | 2000-05-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU2002366641A1 (en) | Methods for inhibiting ocular processes | |
EP1507005A3 (fr) | Modulation antisens de l'expression du gène BCL-X | |
EE04221B1 (et) | Östrogeeni kasutamine ravimi valmistamiseks füüsiliste seisundite raviks menopausijärgsetel isikutel | |
WO2002099075A3 (fr) | Prmt comme modificateurs de la voie p53 et methodes d'utilisation | |
BR9911396A (pt) | Estabilização de enzima por meio de tensoativos catiÈnicos | |
ZA993364B (en) | Novel 4-phenylpiperidines for the treatment of pruritic dermatoses. | |
DE1082412T1 (de) | Transfizierte zellen und methoden zur behandlung von diabetes | |
MX2009006685A (es) | Antagonistas del dr6 y usos de los mismos en el tratamiento de trastornos neurologicos. | |
DK1123414T3 (da) | Antisense-modulering af integrin alpha 4.ekspression | |
WO2000024869A3 (fr) | Methodes de modulation de fusion cellulaire | |
DE69924738D1 (de) | Modulierung von mlk- (multiple lineage kinase) proteinen | |
EP1131107A4 (fr) | Modulation antisens de l'expression de kappa b kinase alpha inhibitrice | |
EP1131332A4 (fr) | Modulation antisens de l'expression de la kappa b kinase beta inhibitrice | |
WO1999049038A3 (fr) | Proteines de fixation du calcium humaines | |
WO2003066821A3 (fr) | Molecules interagissant avec des polynucleotides et polypeptides casl (mical), et procedes d'utilisation associes | |
ATE288498T1 (de) | Methoden zur inhibierung von helicobacter pylori | |
EP1582224A4 (fr) | Procede de traitement de tissu biologique par irradiation par hyperfrequences | |
BR9811643A (pt) | Suplementação quìmica de osso | |
EP1255110A3 (fr) | Méthodes et produits pour l'identification de modulateurs de l'activité des récepteurs P2X7, et leur utilisation pour le traitement des affections squelettiques | |
EP1363528A4 (fr) | Methodes de diagnostic et de traitement des cardiopathies | |
DE19983519T1 (de) | Vorrichtung zur Wärmebehandlung von Körpergewebe | |
WO2004082610A3 (fr) | Modulation d'une interaction de hyaluronane et de cd44, et leurs utilisations dans le traitement de troubles | |
WO2003028536A3 (fr) | Methodes permettant de diagnostiquer et de traiter les maladies cardiaques | |
NZ514691A (en) | Method to type prion proteins | |
BR9915317A (pt) | Método de tratar trombocitopenia induzida por heparina |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
ENP | Entry into the national phase |
Ref country code: AU Ref document number: 2000 12242 Kind code of ref document: A Format of ref document f/p: F |
|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CR CU CZ DE DK DM EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): GH GM KE LS MW SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG |
|
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
WWE | Wipo information: entry into national phase |
Ref document number: 09830169 Country of ref document: US |
|
REG | Reference to national code |
Ref country code: DE Ref legal event code: 8642 |
|
122 | Ep: pct application non-entry in european phase | ||
COP | Corrected version of pamphlet |
Free format text: PAGES 1-13, SEQUENCE LISTING, ADDED |