WO2000023477A3 - Immunoglobulin variants - Google Patents

Immunoglobulin variants Download PDF

Info

Publication number
WO2000023477A3
WO2000023477A3 PCT/GB1999/003386 GB9903386W WO0023477A3 WO 2000023477 A3 WO2000023477 A3 WO 2000023477A3 GB 9903386 W GB9903386 W GB 9903386W WO 0023477 A3 WO0023477 A3 WO 0023477A3
Authority
WO
WIPO (PCT)
Prior art keywords
immunoglobulin variants
cell
polypeptide
immuno
bind
Prior art date
Application number
PCT/GB1999/003386
Other languages
French (fr)
Other versions
WO2000023477A9 (en
WO2000023477A2 (en
Inventor
Birgit Anna Helm
Original Assignee
Univ Sheffield
Birgit Anna Helm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Sheffield, Birgit Anna Helm filed Critical Univ Sheffield
Priority to AU62189/99A priority Critical patent/AU6218999A/en
Priority to EP99949212A priority patent/EP1123317A1/en
Publication of WO2000023477A2 publication Critical patent/WO2000023477A2/en
Publication of WO2000023477A9 publication Critical patent/WO2000023477A9/en
Publication of WO2000023477A3 publication Critical patent/WO2000023477A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

An IgE polypeptide, or effective fragment thereof, wherein said polypeptide contains a modification such that it is able to bind to its receptor at the cell surface of an immune cell but unable to bring about the release of immuno-active agents from said cell populations.
PCT/GB1999/003386 1998-10-20 1999-10-12 Immunoglobulin variants WO2000023477A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU62189/99A AU6218999A (en) 1998-10-20 1999-10-12 Immunoglobulin variants
EP99949212A EP1123317A1 (en) 1998-10-20 1999-10-12 Immunoglobulin variants

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9822763.0 1998-10-20
GBGB9822763.0A GB9822763D0 (en) 1998-10-20 1998-10-20 Immunoglobin variant

Publications (3)

Publication Number Publication Date
WO2000023477A2 WO2000023477A2 (en) 2000-04-27
WO2000023477A9 WO2000023477A9 (en) 2000-09-21
WO2000023477A3 true WO2000023477A3 (en) 2001-04-12

Family

ID=10840812

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1999/003386 WO2000023477A2 (en) 1998-10-20 1999-10-12 Immunoglobulin variants

Country Status (4)

Country Link
EP (1) EP1123317A1 (en)
AU (1) AU6218999A (en)
GB (1) GB9822763D0 (en)
WO (1) WO2000023477A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1967206B1 (en) 2000-08-30 2012-10-10 Pfizer Products Inc. Anti-IgE vaccines
KR101581659B1 (en) * 2004-02-02 2015-12-31 타녹스 인코퍼레이티드 IDENTIFICATION OF NOVEL IgE EPITOPES
IL257628B2 (en) 2015-09-28 2023-04-01 Univ North Carolina Chapel Hill Methods and compositions for antibody-evading virus vectors
AU2019247746B2 (en) 2018-04-03 2024-08-15 Ginkgo Bioworks, Inc. Antibody-evading virus vectors
JP7406677B2 (en) 2018-04-03 2023-12-28 ギンコ バイオワークス インコーポレイテッド Viral vectors that evade antibodies
CA3133453A1 (en) 2019-03-21 2020-09-24 Daniel Mccoy Recombinant adeno-associated virus vectors
TW202128736A (en) 2019-10-17 2021-08-01 美商史崔德生物公司 Adeno-associated viral vectors for treatment of niemann-pick disease type c

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987002671A1 (en) * 1985-11-01 1987-05-07 International Genetic Engineering, Inc. Modular assembly of antibody genes, antibodies prepared thereby and use
WO1991014438A1 (en) * 1990-03-20 1991-10-03 The Trustees Of Columbia University In The City Of New York Chimeric antibodies with receptor binding ligands in place of their constant region
WO1996014333A1 (en) * 1994-11-04 1996-05-17 Peptide Therapeutics Limited Peptides for anti-allergy treatment
WO1996040199A1 (en) * 1995-06-07 1996-12-19 University Of Pennsylvania Methods of inhibiting phagocytosis

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987002671A1 (en) * 1985-11-01 1987-05-07 International Genetic Engineering, Inc. Modular assembly of antibody genes, antibodies prepared thereby and use
WO1991014438A1 (en) * 1990-03-20 1991-10-03 The Trustees Of Columbia University In The City Of New York Chimeric antibodies with receptor binding ligands in place of their constant region
WO1996014333A1 (en) * 1994-11-04 1996-05-17 Peptide Therapeutics Limited Peptides for anti-allergy treatment
WO1996040199A1 (en) * 1995-06-07 1996-12-19 University Of Pennsylvania Methods of inhibiting phagocytosis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NIO NORIKI ET AL: "Inhibition of passive sensitization of human peripheral basophils by synthetic human immunoglobulin E peptide fragments.", FEBS (FEDERATION OF EUROPEAN BIOCHEMICAL SOCIETIES) LETTERS, vol. 319, no. 3, 1993, pages 225 - 228, XP000925116, ISSN: 0014-5793 *

Also Published As

Publication number Publication date
GB9822763D0 (en) 1998-12-16
WO2000023477A9 (en) 2000-09-21
EP1123317A1 (en) 2001-08-16
WO2000023477A2 (en) 2000-04-27
AU6218999A (en) 2000-05-08

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