WO2000023463A3 - Fluorescent dye binding peptides - Google Patents

Fluorescent dye binding peptides Download PDF

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Publication number
WO2000023463A3
WO2000023463A3 PCT/US1999/024266 US9924266W WO0023463A3 WO 2000023463 A3 WO2000023463 A3 WO 2000023463A3 US 9924266 W US9924266 W US 9924266W WO 0023463 A3 WO0023463 A3 WO 0023463A3
Authority
WO
WIPO (PCT)
Prior art keywords
fluorescent dye
binding peptides
dye binding
fluorophore dyes
fluorettes
Prior art date
Application number
PCT/US1999/024266
Other languages
French (fr)
Other versions
WO2000023463A2 (en
WO2000023463A9 (en
Inventor
Garry P Nolan
Michael N Rozinov
Original Assignee
Univ Leland Stanford Junior
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Leland Stanford Junior filed Critical Univ Leland Stanford Junior
Priority to AU11202/00A priority Critical patent/AU1120200A/en
Publication of WO2000023463A2 publication Critical patent/WO2000023463A2/en
Publication of WO2000023463A3 publication Critical patent/WO2000023463A3/en
Publication of WO2000023463A9 publication Critical patent/WO2000023463A9/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
    • G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6827—Total protein determination, e.g. albumin in urine
    • G01N33/6839—Total protein determination, e.g. albumin in urine involving dyes, e.g. Coomassie blue, bromcresol green

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention is directed to novel polypeptides, termed fluorettes, that bind with high avidity to fluorophore dyes. The peptides find use in a variety of methods and approaches involving fluorophore dyes.
PCT/US1999/024266 1998-10-16 1999-10-15 Fluorescent dye binding peptides WO2000023463A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU11202/00A AU1120200A (en) 1998-10-16 1999-10-15 Fluorescent dye binding peptides

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US10446598P 1998-10-16 1998-10-16
US60/104,465 1998-10-16

Publications (3)

Publication Number Publication Date
WO2000023463A2 WO2000023463A2 (en) 2000-04-27
WO2000023463A3 true WO2000023463A3 (en) 2000-08-17
WO2000023463A9 WO2000023463A9 (en) 2001-07-05

Family

ID=22300633

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/024266 WO2000023463A2 (en) 1998-10-16 1999-10-15 Fluorescent dye binding peptides

Country Status (2)

Country Link
AU (1) AU1120200A (en)
WO (1) WO2000023463A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2871464B1 (en) * 2004-06-15 2006-09-08 Centre Nat Rech Scient Cnrse COLLECTIONS OF TRACEABLE COMPOUNDS AND USES THEREOF
US7538187B2 (en) * 2005-08-01 2009-05-26 E. I. Du Pont De Nemours And Company Coloring compositions with peptide-based dispersants and binders
WO2009005579A1 (en) * 2007-06-14 2009-01-08 The General Hospital Corporation High affinity fluorochrome binding peptides
CA2699612C (en) * 2007-09-14 2013-01-08 Biosentinel, Llc Resonance energy transfer assay with cleavage sequence and spacer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LEFEVRE C ET AL: "TEXAS RED-X AND RHODAMINE RED-X, NEW DERIVATIVES OF SULFORHODAMINE 101 AND LISSAMINE RHODAMINE B WITH IMPROVED LABELING AND FLUORESCENCE PROPERTIES", BIOCONJUGATE CHEMISTRY,US,AMERICAN CHEMICAL SOCIETY, WASHINGTON, vol. 7, no. 4, 1996, pages 482 - 489, XP000882552, ISSN: 1043-1802 *

Also Published As

Publication number Publication date
WO2000023463A2 (en) 2000-04-27
WO2000023463A9 (en) 2001-07-05
AU1120200A (en) 2000-05-08

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