WO2000021602A1 - Enceinte d'humidification pour assistance respiratoire - Google Patents

Enceinte d'humidification pour assistance respiratoire Download PDF

Info

Publication number
WO2000021602A1
WO2000021602A1 PCT/NZ1999/000172 NZ9900172W WO0021602A1 WO 2000021602 A1 WO2000021602 A1 WO 2000021602A1 NZ 9900172 W NZ9900172 W NZ 9900172W WO 0021602 A1 WO0021602 A1 WO 0021602A1
Authority
WO
WIPO (PCT)
Prior art keywords
humidification chamber
ultra
adhesive means
chamber
violet light
Prior art date
Application number
PCT/NZ1999/000172
Other languages
English (en)
Inventor
Neil Donald Prime
Original Assignee
Fisher & Paykel Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisher & Paykel Limited filed Critical Fisher & Paykel Limited
Priority to AU10840/00A priority Critical patent/AU1084000A/en
Publication of WO2000021602A1 publication Critical patent/WO2000021602A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/16Devices to humidify the respiration air
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M16/00Devices for influencing the respiratory system of patients by gas treatment, e.g. mouth-to-mouth respiration; Tracheal tubes
    • A61M16/10Preparation of respiratory gases or vapours
    • A61M16/14Preparation of respiratory gases or vapours by mixing different fluids, one of them being in a liquid phase
    • A61M16/16Devices to humidify the respiration air
    • A61M16/162Water-reservoir filling system, e.g. automatic
    • A61M16/164Water-reservoir filling system, e.g. automatic including a liquid inlet valve system
    • A61M16/165Water-reservoir filling system, e.g. automatic including a liquid inlet valve system with a float actuator
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2207/00Methods of manufacture, assembly or production

Definitions

  • This invention relates to seals and more particularly though not solely to humidification apparatus in which a water tight seal between a plastics chamber and a metallic base is provided.
  • Humidification systems suitable for use in providing a humidified supply of gases to a patient in a medical environment usually include a humidification chamber which contains a volume of water with a gases space above the surface of the water through which a gases flow is passed.
  • the humidification chamber is positioned atop a heat source so that water vapour is formed in the gases space and combined with the gases flow to the patient.
  • An example of the aforementioned medical humidification system incorporating a humidification chamber may be seen in our United States patent numbers 4,913,140 and 5,445,143.
  • the base of the chamber is formed from a highly heat conductive material such as Aluminium.
  • the humidification chamber however is designed to retain heat and also to allow a user to easily be able to view the level of water within the chamber so that it may be refilled when necessary. Accordingly, the humidification chamber has been formed from plastics material.
  • the base which is usually circular
  • the base which is usually circular
  • the base with special flanges and to then crimp the edge of the base over the flange of the chamber with a rubber gasket there between. It has been found that seals formed by the above existing process may eventually fail either due to the warm and moist environment and the long durations of on/off cycling which they are subjected to or because the crimp applied to the base is not sufficiently tight.
  • the invention may broadly be said to consist in a humidification chamber adapted to hold a volume of water and to be used in a respiratory humidification system, said humidification chamber comprising: housing means, formed from a substantially plastics material adapted to hold substantially said volume of water, and having a peripheral edge surrounding an open side, a base, formed from a substantially metallic material and adapted for connection to said housing means thereby sealing off said open side, and adhesive means bonding said base and said housing means together around said peripheral edge thereby forming a watertight seal.
  • the invention may broadly be said to consist in a method of sealing a metallic base to a plastics chamber, said method comprising the steps of: a) forming flanged surfaces on said base and said chamber, b) applying ultra-violet activated adhesive means to at least one of said flanged surfaces, c) joining said flanged surfaces together thereby forming a joint, d) applying external pressure on at least one of said flanged surfaces thereby compressing said joint, and e) activating said adhesive means by subj ecting said j oint to an ultra-violet light source.
  • the invention consists in the foregoing and also envisages constructions of which the following gives examples.
  • Figure 1 is a plan view of a humidification chamber according to the preferred embodiment of the present invention.
  • Figure 2 is an exploded cross-sectional front elevation of the humidification chamber of Figure 1 ,
  • FIG. 3 is a block diagram showing the apparatus used to manufacture the present invention
  • Figure 4 is a flowchart showing the process of manufacture
  • Figure 5 is a schematic drawing of a respiratory humidification system incorporating the humidification chamber of Figure 1.
  • a respiratory humidification chamber 1 is shown in accordance with the preferred form of the present invention.
  • the respiratory humidification chamber 1 substantially comprises two parts, a chamber means or dome 2 and a base means or base 3.
  • Dome 2 is preferably formed from a plastics material which is transparent or at least semi-transparent to allow the contents to be visible externally. It can be seen that dome 2 has a substantially inverted cup like shape (as shown in Figure 2) having a circular flange 8 protruding substantially perpendicularly to side wall 9.
  • Dome 2 is preferably provided with a gases inlet 4 and a gases outlet 5, both of which protrude from the upper surface 6 thereof. Dome 2 is also provided with a water inlet 7 which may further be provided with a valve mechanism to regulate the flow of water into the respiratory humidification chamber 1.
  • a suitable plastics material from which the dome may be formed is a combination of general purpose styrene and K-resin in about equal amounts.
  • the base 3 is substantially flat and "disk” shaped having a main supporting section 11 surrounded by a "raised” circular flange 10 protruding from the edge thereof substantially parallel to the main supporting section. A layer of adhesive means or glue 12 are applied between the flanges 8 and 10. As will be described below, it is necessary for base 3 to possess good thermal conductivity properties and we have found that a good material from which base 3 may be formed is anodised aluminium.
  • the adhesive means 12 are, for example, an ultra-violet light cured acrylic adhesive certified for use in medical applications. While a number of adhesives are recognised in the art as being suitable for use with rigid/flexible PVC and polycarbonate, they are not known for use with general purpose styrene.
  • the adhesive used according to the preferred embodiment of the present invention typically contains the following ingredients (percentages are by weight):
  • Samples of the bonded joint were tensile and fatigue tested to establish if the failure pressure limit for the chamber glued joint between the aluminium base and plastic chamber dome is greater than expected loads during use.
  • the approximate pressure on the joint with a chamber pressure of 100 cm H 2 0 is 0.043 N/mm 2 .
  • a chamber pressure of 100cm H 2 0 is considered to be extreme for humidification chambers.
  • Various types of joints were tested to simulate the complex stresses that would be exerted on the humidification chamber. Lap joints simulate any hoop or radial stress, butt/peel joints simulate the peeling action exerted by the chamber pressure acting the top of the plastic dome, and the fatigue test simulates the high fluctuating pressures seen in certain modes of ventilation.
  • the peel joint Assuming an internal chamber pressure of 100cm H 2 0 (lOkPa), the peel joint has a factor of safety (F.O.S) of 35.
  • the lap joint's F.O.S is 110.
  • the fatigue test sample lasted at least 7 days (maximum duration on patient) when oscillated between pressures of 0 to 120 cmH 2 0 @ 5 Hz , while under water at 66 degrees Celsius . Under these conditions the j oint was uncompromised at the end of the seven days. Since under normal conditions the maximum chamber pressure used in high frequency ventilation would be 40 cm H 2 0, the F.O.S is 3. Assembled chambers were also life tested under severe operating conditions as a supplementary test. The chambers were tested for 30 days without any compromise of the glued joint. The joints were tested using the humidifier chamber test procedure specified in IS08185:1998 clause 11.6.1 and 11.6.2. This involves application of 8 kPa static pressure, before and after the test. To pass the test the leak rate must not exceed 10 ml/min.
  • a respiratory humidification system which incorporates the preferred form of respiratory humidification chamber 1 according to the present invention.
  • the respiratory humidification chamber 1 having been sealed as described above, is mounted upon the heater plate 13 of a respiratory humidifier 14.
  • Humidification chamber 1 is provided with a volume of water 15, preferably supplied through water inlet 7 from an external source.
  • Humidification chamber 1 may be provided with a float valve system such as that described in our United States patent number 5,445, 143 so that the water level within the chamber may be maintained at a desirable level.
  • a gases supply or ventilator 18 provides a flow of gases (for example, oxygen or anaesthetic gases) to the gases inlet 4 of the humidification chamber 1. As the water within the chamber is heated it will release water vapour to the gases flow producing humidified gases at the gases outlet 5 which are carried to a patient 19 by an inspiratory conduit 21.
  • gases for example, oxygen or anaesthetic gases
  • Respiratory humidifier 14 also includes control means (not shown) which are programmed to carry out a series of instructions which may include receiving input from a user as to a desirable heater plate 13 or water 15 temperature. Accordingly, temperature sensors may be provided to sense the temperature of the heater plate and temperature and/or flow sensors 16 and 17 may be positioned in the flow of gases exiting the humidification chamber to provide feedback to the controller.
  • a heater wire 20 may be provided within inspiratory conduit 21 to eliminate or reduce the occurrence of condensation or "rain out" within the conduit.
  • the present invention provides a reliable, water tight seal between a general purpose styrene dome and an aluminium base using a UV cured acrylic medically certified adhesive.
  • a seal thus produced is suitable for use in the environment of a humidification chamber which is cyclically warm and substantially constantly wet. This provides a much improved method of sealing a humidification chamber than was known previously.

Abstract

La présente invention concerne un procédé permettant de coller un dôme en plastique sur une base métallique en utilisant une colle acrylique activée par ultraviolets. Le dôme et la base forment ensemble une enceinte d'humidification qui contient un corps rempli d'eau chauffée par la base métallique de façon à humidifier les gaz traversant le sommet du dôme. L'enceinte d'humidification est conçue pour être utilisée dans un appareil d'assistance respiratoire et fournir à son utilisateur des gaz humidifiés sous pression.
PCT/NZ1999/000172 1998-10-13 1999-10-13 Enceinte d'humidification pour assistance respiratoire WO2000021602A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU10840/00A AU1084000A (en) 1998-10-13 1999-10-15 Respiratory humidification chamber

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NZ33228798 1998-10-13
NZ332287 1998-10-13

Publications (1)

Publication Number Publication Date
WO2000021602A1 true WO2000021602A1 (fr) 2000-04-20

Family

ID=19926967

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NZ1999/000172 WO2000021602A1 (fr) 1998-10-13 1999-10-13 Enceinte d'humidification pour assistance respiratoire

Country Status (2)

Country Link
AU (1) AU1084000A (fr)
WO (1) WO2000021602A1 (fr)

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004112873A1 (fr) * 2003-06-20 2004-12-29 Resmed Limited Appareil respiratoire pour inhalation de gaz, muni d'un humidificateur
US7997270B2 (en) 2001-08-20 2011-08-16 Map Medizin-Technologie Gmbh Apparatus for supplying respiratory gas and a method for controlling the apparatus
US8181938B2 (en) 2006-08-10 2012-05-22 Intersurgical Ag Humidification chambers
US8210177B2 (en) 2006-08-10 2012-07-03 Intersurgical Ag Humidification chambers
US8733349B2 (en) 2009-07-31 2014-05-27 Resmed Limited Wire heated tube with temperature control system, tube type detection, and active over temperature protection for humidifier for respiratory apparatus
US8789525B2 (en) 2007-06-07 2014-07-29 Resmed Limited Tub for humidifier
US9038631B2 (en) 2003-06-20 2015-05-26 Resmed Limited Breathable gas apparatus with humidifier
US9272116B2 (en) 1999-08-05 2016-03-01 Resmed R&D Germany Gmbh Apparatus for humidifying a respiratory gas
USRE46079E1 (en) 2001-02-16 2016-07-26 Resmed Limited Humidifier with structure to prevent backflow of liquid through the humidifier inlet
US9572949B2 (en) 2013-02-01 2017-02-21 Resmed Limited Wire heated tube with temperature control system for humidifier for respiratory apparatus
US9610416B2 (en) 2009-06-04 2017-04-04 Resmed Limited Flow generator chassis assembly with suspension seal
US9802022B2 (en) 2008-03-06 2017-10-31 Resmed Limited Humidification of respiratory gases
US9855398B2 (en) 2006-11-08 2018-01-02 Resmed Limited Humidifier for respiratory apparatus
EP3441103A1 (fr) * 2017-08-08 2019-02-13 Air Liquide Medical Systems Réservoir à eau pour humidificateur de gaz à plaque chauffante collée
EP3560539A1 (fr) * 2018-04-24 2019-10-30 ResMed R&D Germany GmbH Tube à utiliser dans un humidificateur
US10806889B2 (en) 2008-06-05 2020-10-20 ResMed Pty Ltd Treatment of respiratory conditions
USD899598S1 (en) 2018-09-04 2020-10-20 3B Medical, Inc. CPAP device
US11013875B2 (en) 2005-08-15 2021-05-25 ResMed Pty Ltd Low cost CPAP flow generator and humidifier assembly

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284878A (en) * 1979-08-20 1981-08-18 Bourns Medical Systems, Inc. Fluid level detector
JPS59226013A (ja) * 1983-06-07 1984-12-19 Yokohama Rubber Co Ltd:The 紫外線硬化型樹脂組成物
JPH0364389A (ja) * 1989-08-03 1991-03-19 Toshiba Silicone Co Ltd 紫外線硬化型シリコーン接着剤組成物
JPH04268315A (ja) * 1991-02-22 1992-09-24 Toshiba Silicone Co Ltd 嫌気及び紫外線硬化性ポリオルガノシロキサン組成物

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4284878A (en) * 1979-08-20 1981-08-18 Bourns Medical Systems, Inc. Fluid level detector
JPS59226013A (ja) * 1983-06-07 1984-12-19 Yokohama Rubber Co Ltd:The 紫外線硬化型樹脂組成物
JPH0364389A (ja) * 1989-08-03 1991-03-19 Toshiba Silicone Co Ltd 紫外線硬化型シリコーン接着剤組成物
JPH04268315A (ja) * 1991-02-22 1992-09-24 Toshiba Silicone Co Ltd 嫌気及び紫外線硬化性ポリオルガノシロキサン組成物

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DATABASE WPI Derwent World Patents Index; Class A21, AN 1985-033502/06 *
DATABASE WPI Derwent World Patents Index; Class A26, AN 1992-368577/45 *
DATABASE WPI Derwent World Patents Index; Class A81, AN 1991-123038/17 *

Cited By (63)

* Cited by examiner, † Cited by third party
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US10052450B2 (en) 1999-08-05 2018-08-21 Resmed R&D Germany Gmbh Apparatus for humidifying a respiratory gas
US9545493B2 (en) 1999-08-05 2017-01-17 Resmed R&D Germany Gmbh Apparatus for humidifying a respiratory gas
US9302067B2 (en) 1999-08-05 2016-04-05 Resmed R&D Germany Gmbh Apparatus for humidifying a respiratory gas
US9272116B2 (en) 1999-08-05 2016-03-01 Resmed R&D Germany Gmbh Apparatus for humidifying a respiratory gas
US9545494B2 (en) 1999-08-05 2017-01-17 Resmed R&D Germany Gmbh Apparatus for humidifying a respiratory gas
US9555211B2 (en) 1999-08-05 2017-01-31 Resmed R&D Germany Gmbh Apparatus for humidifying a respiratory gas
US9884163B2 (en) 1999-08-05 2018-02-06 RedMed R&D Germany GmbH Apparatus for humidifying a respiratory gas
USRE46571E1 (en) 2001-02-16 2017-10-17 Resmed Limited Humidifier with structure to prevent backflow of liquid through the humidifier inlet
USRE46079E1 (en) 2001-02-16 2016-07-26 Resmed Limited Humidifier with structure to prevent backflow of liquid through the humidifier inlet
USRE48095E1 (en) 2001-02-16 2020-07-14 ResMed Pty Ltd Humidifier with structure to prevent backflow of liquid through the humidifier inlet
USRE48118E1 (en) 2001-02-16 2020-07-28 ResMed Pty Ltd Humidifier with structure to prevent backflow of liquid through the humidifier inlet
USRE48149E1 (en) 2001-02-16 2020-08-11 ResMed Pty Ltd Humidifier with structure to prevent backflow of liquid through the humidifier inlet
US10112027B2 (en) 2001-08-20 2018-10-30 Resmed R&D Germany Gmbh Apparatus for supplying respiratory gas and a method for controlling the apparatus
US8671936B2 (en) 2001-08-20 2014-03-18 Resmed R&D Germany Gmbh Apparatus for supplying respiratory gas and a method for controlling the apparatus
US7997270B2 (en) 2001-08-20 2011-08-16 Map Medizin-Technologie Gmbh Apparatus for supplying respiratory gas and a method for controlling the apparatus
US10201676B2 (en) 2003-06-20 2019-02-12 Resmed Limited Breathable gas supply apparatus
US11235115B2 (en) 2003-06-20 2022-02-01 ResMed Pty Ltd Breathable gas apparatus with humidifier
US9358359B2 (en) 2003-06-20 2016-06-07 Resmed Limited Breathable gas apparatus with humidifier
US9227035B2 (en) 2003-06-20 2016-01-05 Resmed Limited Breathable gas apparatus with humidifier
US9072860B2 (en) 2003-06-20 2015-07-07 Resmed Limited Breathable gas apparatus with humidifier
US11413412B2 (en) 2003-06-20 2022-08-16 ResMed Pty Ltd Breathable gas supply apparatus
US9610420B2 (en) 2003-06-20 2017-04-04 Resmed Limited Breathable gas apparatus with humidifier
US11260187B2 (en) 2003-06-20 2022-03-01 ResMed Pty Ltd Breathable gas supply apparatus
USRE46543E1 (en) 2003-06-20 2017-09-12 Resmed Limited Breathable gas apparatus with humidifier
US9038632B2 (en) 2003-06-20 2015-05-26 Resmed Limited Breathable gas apparatus with humidifier
US9539409B2 (en) 2003-06-20 2017-01-10 Resmed Limited Breathable gas apparatus with humidifier
US10881820B2 (en) 2003-06-20 2021-01-05 ResMed Pty Ltd Breathable gas apparatus with humidifier
US9038631B2 (en) 2003-06-20 2015-05-26 Resmed Limited Breathable gas apparatus with humidifier
US10850053B2 (en) 2003-06-20 2020-12-01 ResMed Pty Ltd Breathable gas supply apparatus
US10293125B2 (en) 2003-06-20 2019-05-21 Resmed Limited Flow generator with patient reminder
WO2004112873A1 (fr) * 2003-06-20 2004-12-29 Resmed Limited Appareil respiratoire pour inhalation de gaz, muni d'un humidificateur
US11298482B2 (en) 2005-08-15 2022-04-12 ResMed Pty Ltd Low cost CPAP flow generator and humidifier assembly
US11013875B2 (en) 2005-08-15 2021-05-25 ResMed Pty Ltd Low cost CPAP flow generator and humidifier assembly
US8181938B2 (en) 2006-08-10 2012-05-22 Intersurgical Ag Humidification chambers
US8181940B2 (en) 2006-08-10 2012-05-22 Intersurgical Ag Humidification chambers
US8210177B2 (en) 2006-08-10 2012-07-03 Intersurgical Ag Humidification chambers
US11338104B2 (en) 2006-11-08 2022-05-24 ResMed Pty Ltd Humidifier for respiratory apparatus
US11712535B2 (en) 2006-11-08 2023-08-01 ResMed Pty Ltd Humidifier for respiratory apparatus
US9855398B2 (en) 2006-11-08 2018-01-02 Resmed Limited Humidifier for respiratory apparatus
US10478585B2 (en) 2007-06-07 2019-11-19 ResMed Pty Ltd Tub for humidifier
US8789525B2 (en) 2007-06-07 2014-07-29 Resmed Limited Tub for humidifier
US9802022B2 (en) 2008-03-06 2017-10-31 Resmed Limited Humidification of respiratory gases
US11229766B2 (en) 2008-06-05 2022-01-25 ResMed Pty Ltd Treatment of respiratory conditions
US11433213B2 (en) 2008-06-05 2022-09-06 ResMed Pty Ltd Treatment of respiratory conditions
US10806889B2 (en) 2008-06-05 2020-10-20 ResMed Pty Ltd Treatment of respiratory conditions
US11247019B2 (en) 2008-06-05 2022-02-15 ResMed Pty Ltd Treatment of respiratory conditions
US11878123B2 (en) 2008-06-05 2024-01-23 ResMed Pty Ltd Treatment of respiratory conditions
US11129948B2 (en) 2009-06-04 2021-09-28 ResMed Pty Ltd Flow generator chassis assembly with suspension seal
US9610416B2 (en) 2009-06-04 2017-04-04 Resmed Limited Flow generator chassis assembly with suspension seal
US10086158B2 (en) 2009-07-31 2018-10-02 Resmed Limited Wire heated tube with temperature control system, tube type detection, and active over temperature protection for humidifier for respiratory apparatus
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US11707587B2 (en) 2009-07-31 2023-07-25 ResMed Pty Ltd Wire heated tube with temperature control system, tube type detection, and active over temperature protection for humidifier for respiratory apparatus
US8733349B2 (en) 2009-07-31 2014-05-27 Resmed Limited Wire heated tube with temperature control system, tube type detection, and active over temperature protection for humidifier for respiratory apparatus
US11607512B2 (en) 2009-07-31 2023-03-21 ResMed Pty Ltd Wire heated tube with temperature control system, tube type detection, and active over temperature protection for humidifier for respiratory apparatus
US11260186B2 (en) 2013-02-01 2022-03-01 ResMed Pty Ltd Wire heated tube with temperature control system for humidifier for respiratory apparatus
US9572949B2 (en) 2013-02-01 2017-02-21 Resmed Limited Wire heated tube with temperature control system for humidifier for respiratory apparatus
US10363382B2 (en) 2013-02-01 2019-07-30 ResMed Pty Ltd Wire heated tube with temperature control system for humidifier for respiratory apparatus
US11779719B2 (en) 2013-02-01 2023-10-10 ResMed Pty Ltd Wire heated tube with temperature control system for humidifier for respiratory apparatus
FR3070012A1 (fr) * 2017-08-08 2019-02-15 Air Liquide Medical Systems Reservoir a eau pour humidificateur de gaz a plaque chauffante collee
EP3441103A1 (fr) * 2017-08-08 2019-02-13 Air Liquide Medical Systems Réservoir à eau pour humidificateur de gaz à plaque chauffante collée
US11376392B2 (en) 2018-04-24 2022-07-05 ResMed Pty Ltd Tub for use in a humidifier
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USD899598S1 (en) 2018-09-04 2020-10-20 3B Medical, Inc. CPAP device

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