WO2000018796A3 - Secretory protein- zsig48 - Google Patents

Secretory protein- zsig48 Download PDF

Info

Publication number
WO2000018796A3
WO2000018796A3 PCT/US1999/022970 US9922970W WO0018796A3 WO 2000018796 A3 WO2000018796 A3 WO 2000018796A3 US 9922970 W US9922970 W US 9922970W WO 0018796 A3 WO0018796 A3 WO 0018796A3
Authority
WO
WIPO (PCT)
Prior art keywords
zsig48
secretory protein
polypeptides
leukocytes
antibodies
Prior art date
Application number
PCT/US1999/022970
Other languages
French (fr)
Other versions
WO2000018796A2 (en
Inventor
Si Lok
Paul O Sheppard
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to CA002344712A priority Critical patent/CA2344712A1/en
Priority to IL14219399A priority patent/IL142193A0/en
Priority to AU65069/99A priority patent/AU6506999A/en
Priority to JP2000572254A priority patent/JP2002525100A/en
Priority to EP99953037A priority patent/EP1117793A2/en
Publication of WO2000018796A2 publication Critical patent/WO2000018796A2/en
Publication of WO2000018796A3 publication Critical patent/WO2000018796A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Secretory Protein - 48 (Zsig48), polypeptides, polynucleotides encoding said polypeptides, antibodies which specifically bind to Zsig48 and anti-idiotypic antibodies. Zsig48 polypeptides cause leukocytes to proliferate and thus can be used to elevate leukocytes in cancer treatments and in immunosuppressed patients.
PCT/US1999/022970 1998-10-01 1999-10-01 Secretory protein- zsig48 WO2000018796A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
CA002344712A CA2344712A1 (en) 1998-10-01 1999-10-01 Secretory protein- zsig48
IL14219399A IL142193A0 (en) 1998-10-01 1999-10-01 Secretory protein -48
AU65069/99A AU6506999A (en) 1998-10-01 1999-10-01 Secretory protein - 48
JP2000572254A JP2002525100A (en) 1998-10-01 1999-10-01 Secreted protein 48
EP99953037A EP1117793A2 (en) 1998-10-01 1999-10-01 Secretory protein - zsig48

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16474098A 1998-10-01 1998-10-01
US09/164,740 1998-10-01

Publications (2)

Publication Number Publication Date
WO2000018796A2 WO2000018796A2 (en) 2000-04-06
WO2000018796A3 true WO2000018796A3 (en) 2000-09-28

Family

ID=22595886

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/022970 WO2000018796A2 (en) 1998-10-01 1999-10-01 Secretory protein- zsig48

Country Status (7)

Country Link
EP (1) EP1117793A2 (en)
JP (1) JP2002525100A (en)
AU (1) AU6506999A (en)
CA (1) CA2344712A1 (en)
IL (1) IL142193A0 (en)
WO (1) WO2000018796A2 (en)
ZA (1) ZA200102310B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP5097412B2 (en) * 2006-10-13 2012-12-12 株式会社日本触媒 Protein intracellular introduction agent

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998036067A2 (en) * 1997-02-14 1998-08-20 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998036067A2 (en) * 1997-02-14 1998-08-20 Genetics Institute, Inc. Secreted proteins and polynucleotides encoding them

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
EMBL DATABASE EMHUM1:AC005534; ACCESSION-NO.: AC005534, 27 August 1998 (1998-08-27), XP002142669 *
SULSTON, J.E. AND WATERSTON, R.: "Toward a complete human genome sequence", GENOME RESEARCH, vol. 8, no. 11, - 1998, pages 1097 - 1108, XP000910017 *
YAMAGOE, S. ET AL.: "Molecular cloning, structural characterization, and chromosomal mapping of the human LECT2 gene", GENOMICS, vol. 48, no. 3, 15 March 1998 (1998-03-15), pages 324 - 329, XP000915545 *

Also Published As

Publication number Publication date
WO2000018796A2 (en) 2000-04-06
ZA200102310B (en) 2001-10-26
IL142193A0 (en) 2002-03-10
AU6506999A (en) 2000-04-17
JP2002525100A (en) 2002-08-13
EP1117793A2 (en) 2001-07-25
CA2344712A1 (en) 2000-04-06

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