WO2000016729A1 - Container for intravenous administration - Google Patents
Container for intravenous administration Download PDFInfo
- Publication number
- WO2000016729A1 WO2000016729A1 PCT/EP1999/006976 EP9906976W WO0016729A1 WO 2000016729 A1 WO2000016729 A1 WO 2000016729A1 EP 9906976 W EP9906976 W EP 9906976W WO 0016729 A1 WO0016729 A1 WO 0016729A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- insert
- container
- cannula
- injection means
- fluid
- Prior art date
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
- B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
- B65D47/00—Closures with filling and discharging, or with discharging, devices
- B65D47/04—Closures with discharging devices other than pumps
- B65D47/20—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge
- B65D47/24—Closures with discharging devices other than pumps comprising hand-operated members for controlling discharge with poppet valves or lift valves, i.e. valves opening or closing a passageway by a relative motion substantially perpendicular to the plane of the seat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1412—Containers with closing means, e.g. caps
- A61J1/1425—Snap-fit type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
- A61J1/1481—Inlet or outlet ports with connection retaining means, e.g. thread or snap-fit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/18—Arrangements for indicating condition of container contents, e.g. sterile condition
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1468—Containers characterised by specific material properties
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/1475—Inlet or outlet ports
- A61J1/1487—Inlet or outlet ports with friction fit, e.g. connecting tubes directly to a protruding port
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S604/00—Surgery
- Y10S604/905—Aseptic connectors or couplings, e.g. frangible, piercable
Definitions
- the present invention relates to a device for storing and administering a medical fluid, comprising a sealed flexible generally bottle formed container provided with an insert in its opening to which an injection means can be attached.
- This bottled formed container is suitable for repeated collection of fluid with a syringe needle piercing its elastomer containing resilient sealing insert.
- This type of containers has many advantages from their cheap and efficient production method and they will successfully replace glass bottles or ampoules in numerous applications.
- a drawback with these containers is that it requires a certain skill and accuracy to correctly pierce the insert to establish fluid communication between the bottle and syringe so as to collect a desired amount of stored fluid for adminstration to a patient or for transfer to another container.
- EP 0 088 056 and EP 0 326 391 disclose plastic bottle formed ampoules having twist off heads and neck parts formed as a female luer so as to fit with the male luer heads of a connected syringe when transferring fluids from the bottle to the syringe.
- the transferring step using an attachable syringe results in an extra routine and thereby a risk for contamination and faulty handling.
- FR 27 18 017 discloses a bottle for liquid pharmaceuticals made of a polymeric material which is sealed with a detachable cap.
- the bottle has top part formed as a male luer like connection to a cannula (or a similar device) with corresponding form.
- a lock ring 1 1 is engaged over the flange 10 bottle opening.
- the lock ring will serve as safe and tight connecting piece between the bottle opening and the cannula.
- the European patent application 0 788 804 describes a flexible bottle of a polymeric material.
- the bottle may contain a rinse fluid (sodium chloride solution) which for example can be used for flushing a catheter connected to a vein of a patient, just before the infusion of a drug or a parenteral nutrient.
- a rinse fluid sodium chloride solution
- It generally comprises a bottle with a cap which the user removes to free its opening .
- a separate connecting piece with attachment means for a cannula is inserted into the opening.
- the assembled device is thereby ready to be used for administering the contents of the bottle to a patient, or for transferring of the fluid into another container.
- the device of EP 0 788 804 suffers from a number of obvious drawbacks.
- the inserting procedure of the connector is inconvenient and results in additional handling for the hospital personal and will always include a risk for inadvertent contamination of the fluid.
- the device if used for vein flushing, may deliver air bubbles with the fluid when the fluid is administered by squeezing the flexible bottle. The introduction of air bubbles into the blood system can not be tolerated due to the risk of embolism
- US 5,538,306 reveals a construction of such a bottle formed squeezable containers attachable to a cannula which aims to overcome the problems, but is complicated in construction and requires a prescribed handling including several steps.
- the present invention relates to a device for storing and administering a medical fluid, comprising a sealed flexible container which is generally bottle formed or of a similar shape.
- the container In its front end, the container is provided with an opening part, in which an insert is sealingly positioned.
- the container is formed during its manufacturing so it directly extends into sealing cap over said insert.
- the cap is removable by being provided with weak line or a similarly rupturable zone so the user by a simple twisting motion may remove the entire cap or a substantial part thereof to expose the insert when the fluid in the container shall be used and fluid communication shall be established between the container and an attachable injection means, preferably with a conventionally shaped cannula comprising a front needle part connected to generally conical hollow rear part. This is accomplished by that the rear part of the cannula is attached to a generally tubular part of the insert with a generally conical shape in cross-section fitting with the hollow part of the cannula.
- the tubular part of the insert and the hollow part of the cannula are cooperating luer fittings, so said tubular part corresponds to male luer fitting and said hollow part corresponds to a female luer fitting.
- the insert is provided with a engagement means which comprises a radially extended annular recess in the insert which extends axially into the insert a sufficient distance to secure the attachment of a conventional cannula having a rear end shaped as a female luer fitting.
- the outer periphery of the annular recess preferably is provided with screw threaded grooves, so as to form a luer lock attachment between the cannula and the insert of the device.
- the insert is provided with means so that it only admits fluid communication in one direction. Furthermore, the insert is capable of be sealed if fluid passes from the injection device through the insert into the container. This is preferably accomplished by that inserted is provided with a membrane in its fluid channel which is displaceable between a first sealing position to a second open position if a pressure is exerted on the flexible container. Preferably the membrane is axially displaceable between two predetermined positions in order to act as a check valve mechanism.
- Suitable opening pressures for valves in the present invention are less than about 2.5 mm H 2 O and preferably less than about 1 mm H 2 O.
- the membrane is displaced to a sealing position by the blood pressure of the patient, so that blood not inadvertently will be sucked out into the device. It is suitable that the opening pressure of the valve mechanism must be larger than the blood pressure of the patient.
- the bottle formed container of the device can be bellows formed to facilitate the squeezing motion required during the adminstration of its contents.
- the bottle formed container can also be provided with means indicating the levels of fluid and the size of required doses to be administered.
- the inventive device can be manufactured with a conventional blow-fill-seal method as is more closely in the aforementioned patent specifications EP 0 670 709 and US 4,342,184.
- Such method includes blow molding of a polymeric material into bottle formed shape which is filled with medical fluid, whereupon the insert is placed in the opening of the container which is finally sealed by forming a removable cap over the insert from the polymeric material.
- the finally assembled device can be subjected to a sterilization step by high pressure steam (autoclavation) or by means of irradiation before leaving the manufacturing plant.
- the inventive device will find use in a large number of applications besides flushing of infusion means with sodium chloride solution. For example, it will be useful for supplementation of a complementary fluid to an infusion bag by piercing one of its ports, just prior to adminstration of the contents of the bag. It will also be conceivable to use the device as a single or plural dose syringe for direct adminstration to a patient by injection of for example antithrombotic agents such as heparin or low-molecular weight heparins like Fragmin®.
- Fig. 1 shows a schematic view of the container with an axial split view of the insert.
- the device comprises a generally bottle formed container body 10 with opening part 12 in its front end where an insert 20 is positioned.
- the container extends directly into a sealing cap 14 which is made easily removable by a twisting motion of the user. For this reason the cap is provided with a preformed break line 15 which is easily rupturable.
- the insert has a generally tubular part 22 which can be in fluid connection with the container body. The front end of the tubular part is sealed with a plug 21 which is intended to be removed at the same time the cap is ruptured.
- the tubular part has a generally conical shape in cross-section so as to fit a correspondingly shaped rear hollow part of a cannula.
- the cannula can thereby be attached to the tubular part with a luer fitting.
- the insert is provided with an annular recess 24 which extends a suitable axial distance in the insert.
- the recess can be provided with screw-threaded grooves 25 to improve on the engagement with the cannula.
- the dimension of these parts are selected so that they comply with the ISO/DIN standards for male and female luer fittings.
- To accomplish fluid communication only in one direction through the insert is provided with a valve mechanism.
- the insert comprises two parts, a front part 20A with the aforementioned tubular part and the annular recess capable establishing a luer lock connection to a cannula and rear part 20B.
- the parts of the insert are preferably both made of the same compatible polymer material and tightly welded together with conventional means.
- the rear part of the insert is provided with a sealing membrane 26 accommodated in a housing 27 which is in fluid connection with the channel 23 going through the tubular part 22 and the channel 28.
- the membrane is an elastic sealing silicon membrane attached in its housing 27, wherein it is axially displaceable between an open position and a sealed position.
- the membrane and the housing is dimensioned so that it admits fluid communication with the channel 23 when a predetermined positive pressure is exerted on the container 10, for example by squeezing it, otherwise the mechanism remains in its sealing position.
- the rear part of the insert will thereby act as a check valve and is capable to close and seal the device if the attached cannula is in intravenous contact with a patient and the blood pressure is exerted on the valve mechanism until a pressure exceeding the blood pressure is exerted on the container when administering medical fluid to the patient.
- the accordingly designed insert will provide a device which is useful both as a flushing and rinsing means for intravenous administration provisionally connected to vein of a patient and for conventional adminstration by injection of dose of a medical fluid without risking to accidentally administer air into patient that, for example, may sucked into the device by inadvertent handling.
- the handling of the container will be extremely simple and reliable and is initially restricted to the measures of removing the cap along the preformed break line and attaching the cannula to the insert.
- the container can then, if necessary, subjected to a de-aeration step by gently squeezing it in an upright position until fluid expels from the needle and/or no visible signs of air bubbles remain.
- the administration can thereafter be performed by simply squeezing the container in a prescribed manner.
- the device is preferably made substantially from polymer materials which is possible to recycle together without unnecessary labor to dismantle it and separately collect its parts.
- a preferred material for the container is polyolefins, especially polypropylenes and copolymers thereof.
- the insert can be made of polypropylenes or polycarbonates. The minor contribution of the latex membrane from the valve will not interfere with normal recycling applications, since its weight represents less than 1 % of the entire container.
Abstract
Description
Claims
Priority Applications (15)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE69904350T DE69904350T2 (en) | 1998-09-22 | 1999-09-21 | CONTAINER FOR INTRAVENOUS APPLICATION |
PL346837A PL190818B1 (en) | 1998-09-22 | 1999-09-21 | Container for intravenous administration |
SI9930065T SI1115362T1 (en) | 1998-09-22 | 1999-09-21 | Container for intravenous administration |
EP99948808A EP1115362B1 (en) | 1998-09-22 | 1999-09-21 | Container for intravenous administration |
AT99948808T ATE228813T1 (en) | 1998-09-22 | 1999-09-21 | CONTAINER FOR INTRAVENOUS APPLICATION |
DK99948808T DK1115362T3 (en) | 1998-09-22 | 1999-09-21 | Container for intravenous administration |
BR9914045-4A BR9914045A (en) | 1998-09-22 | 1999-09-21 | Container for intravenous administration |
SK238-2001A SK285419B6 (en) | 1998-09-22 | 1999-09-21 | Arrangement for storing and administering a medical fluid |
HU0103852A HU229203B1 (en) | 1998-09-22 | 1999-09-21 | Container for intravenous administration |
CA002345005A CA2345005C (en) | 1998-09-22 | 1999-09-21 | Container for intravenous administration |
NZ510060A NZ510060A (en) | 1998-09-22 | 1999-09-21 | Container for intravenous administration with container extending into insert having non-return valve, for insertion of cannula |
JP2000573690A JP2002526201A (en) | 1998-09-22 | 1999-09-21 | Intravenous container |
US09/812,866 US6796971B2 (en) | 1998-09-22 | 2001-03-21 | Container for intravenous administration |
NO20011438A NO322207B1 (en) | 1998-09-22 | 2001-03-21 | Container for intravenous administration |
HK02100323.6A HK1039049B (en) | 1998-09-22 | 2002-01-16 | Container for intravenous administration |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9803209-7 | 1998-09-22 | ||
SE9803209A SE9803209L (en) | 1998-09-22 | 1998-09-22 | Container for intravenous administration |
US10160498P | 1998-09-24 | 1998-09-24 | |
US60/101,604 | 1998-09-24 |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/812,866 Continuation US6796971B2 (en) | 1998-09-22 | 2001-03-21 | Container for intravenous administration |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2000016729A1 true WO2000016729A1 (en) | 2000-03-30 |
Family
ID=26663402
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1999/006976 WO2000016729A1 (en) | 1998-09-22 | 1999-09-21 | Container for intravenous administration |
Country Status (19)
Country | Link |
---|---|
US (1) | US6796971B2 (en) |
EP (1) | EP1115362B1 (en) |
JP (1) | JP2002526201A (en) |
CN (1) | CN1184948C (en) |
AT (1) | ATE228813T1 (en) |
BR (1) | BR9914045A (en) |
CA (1) | CA2345005C (en) |
CZ (1) | CZ300605B6 (en) |
DE (1) | DE69904350T2 (en) |
DK (1) | DK1115362T3 (en) |
ES (1) | ES2188249T3 (en) |
HK (1) | HK1039049B (en) |
HU (1) | HU229203B1 (en) |
NO (1) | NO322207B1 (en) |
NZ (1) | NZ510060A (en) |
PT (1) | PT1115362E (en) |
SK (1) | SK285419B6 (en) |
TR (1) | TR200100808T2 (en) |
WO (1) | WO2000016729A1 (en) |
Families Citing this family (20)
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US6485460B2 (en) * | 2001-01-12 | 2002-11-26 | Bracco Diagnostics, Inc. | Tamper evident syringe barrel |
GB0201677D0 (en) * | 2002-01-25 | 2002-03-13 | Glaxo Group Ltd | Medicament dispenser |
DE20215807U1 (en) * | 2002-10-15 | 2003-01-02 | Transcoject Gmbh | syringe barrel |
US7188750B2 (en) * | 2003-09-05 | 2007-03-13 | Hospira, Inc. | Blow fill sealed container with twist off top operated by overcap and method of forming the same |
US8137329B2 (en) | 2004-03-25 | 2012-03-20 | Medindica-Pak, Inc. | Method and apparatus for transforming a delivery container into a waste disposal system |
US8118795B2 (en) | 2005-03-22 | 2012-02-21 | Medindica-Pak, Inc | Disposal chain supply systems method and apparatus |
US7993304B2 (en) * | 2006-03-15 | 2011-08-09 | Bioquiddity, Inc. | Fluid dispensing apparatus |
DE102007024539A1 (en) | 2007-05-24 | 2008-11-27 | Fresenius Kabi Deutschland Gmbh | Cap for a container for holding liquids, in particular an enteral nutrient solution and container with such a cap |
US7736328B2 (en) | 2007-07-05 | 2010-06-15 | Baxter International Inc. | Dialysis system having supply container autoconnection |
CN101721309A (en) * | 2008-11-03 | 2010-06-09 | 马伟博 | Infusion bag and infusion apparatus matched with same |
CN101856306B (en) * | 2009-04-13 | 2013-02-27 | 马伟博 | Bottle cap of glass medicine bottle |
US8955557B2 (en) | 2010-05-12 | 2015-02-17 | Medindica-Pak, Inc. | Environmental NuChain enterprise resource planning method and apparatus |
US8540689B2 (en) | 2010-05-14 | 2013-09-24 | Medindica-Pak, Inc | NuChain NuPurposing container conditioning method and apparatus |
USD655017S1 (en) | 2010-06-17 | 2012-02-28 | Yukon Medical, Llc | Shroud |
USD681230S1 (en) | 2011-09-08 | 2013-04-30 | Yukon Medical, Llc | Shroud |
EP3342392B1 (en) * | 2012-02-02 | 2019-06-26 | Becton Dickinson Holdings Pte. Ltd. | Adaptor for coupling with a medical container |
US9132238B2 (en) * | 2012-06-26 | 2015-09-15 | Becton, Dickinson And Company | Blow fill seal luer syringe |
DE102014008611A1 (en) * | 2014-06-06 | 2015-12-17 | Kocher-Plastik Maschinenbau Gmbh | container |
TWI582608B (en) | 2016-04-06 | 2017-05-11 | 廣達電腦股份有限公司 | Cloud video system |
AU2017261342A1 (en) | 2016-05-06 | 2018-12-13 | Gambro Lundia Ab | Systems and methods for peritoneal dialysis having point of use dialysis fluid preparation using water accumulator and disposable set |
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- 1999-09-21 HU HU0103852A patent/HU229203B1/en unknown
- 1999-09-21 CA CA002345005A patent/CA2345005C/en not_active Expired - Lifetime
- 1999-09-21 DE DE69904350T patent/DE69904350T2/en not_active Expired - Lifetime
- 1999-09-21 AT AT99948808T patent/ATE228813T1/en not_active IP Right Cessation
- 1999-09-21 CZ CZ20011036A patent/CZ300605B6/en not_active IP Right Cessation
- 1999-09-21 SK SK238-2001A patent/SK285419B6/en not_active IP Right Cessation
- 1999-09-21 TR TR200100808T patent/TR200100808T2/en unknown
- 1999-09-21 NZ NZ510060A patent/NZ510060A/en unknown
- 1999-09-21 EP EP99948808A patent/EP1115362B1/en not_active Expired - Lifetime
- 1999-09-21 DK DK99948808T patent/DK1115362T3/en active
- 1999-09-21 JP JP2000573690A patent/JP2002526201A/en active Pending
- 1999-09-21 ES ES99948808T patent/ES2188249T3/en not_active Expired - Lifetime
- 1999-09-21 WO PCT/EP1999/006976 patent/WO2000016729A1/en active IP Right Grant
- 1999-09-21 PT PT99948808T patent/PT1115362E/en unknown
- 1999-09-21 BR BR9914045-4A patent/BR9914045A/en not_active IP Right Cessation
- 1999-09-21 CN CNB998112046A patent/CN1184948C/en not_active Expired - Lifetime
-
2001
- 2001-03-21 US US09/812,866 patent/US6796971B2/en not_active Expired - Lifetime
- 2001-03-21 NO NO20011438A patent/NO322207B1/en not_active IP Right Cessation
-
2002
- 2002-01-16 HK HK02100323.6A patent/HK1039049B/en not_active IP Right Cessation
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Also Published As
Publication number | Publication date |
---|---|
JP2002526201A (en) | 2002-08-20 |
HK1039049A1 (en) | 2002-04-12 |
HUP0103852A2 (en) | 2002-02-28 |
NO20011438D0 (en) | 2001-03-21 |
HUP0103852A3 (en) | 2002-04-29 |
HU229203B1 (en) | 2013-09-30 |
DE69904350D1 (en) | 2003-01-16 |
DK1115362T3 (en) | 2003-03-24 |
NO322207B1 (en) | 2006-08-28 |
US6796971B2 (en) | 2004-09-28 |
CN1184948C (en) | 2005-01-19 |
SK2382001A3 (en) | 2001-10-08 |
ATE228813T1 (en) | 2002-12-15 |
TR200100808T2 (en) | 2001-07-23 |
CA2345005A1 (en) | 2000-03-30 |
SK285419B6 (en) | 2007-01-04 |
CZ20011036A3 (en) | 2001-09-12 |
NZ510060A (en) | 2002-10-25 |
ES2188249T3 (en) | 2003-06-16 |
CZ300605B6 (en) | 2009-06-24 |
PT1115362E (en) | 2003-04-30 |
NO20011438L (en) | 2001-03-21 |
DE69904350T2 (en) | 2003-10-09 |
EP1115362B1 (en) | 2002-12-04 |
CN1318999A (en) | 2001-10-24 |
US20020128612A1 (en) | 2002-09-12 |
BR9914045A (en) | 2001-06-12 |
CA2345005C (en) | 2008-02-12 |
HK1039049B (en) | 2003-03-14 |
EP1115362A1 (en) | 2001-07-18 |
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