WO2000011142A3 - Methyltransferases, nucleic acid molecules encoding methyltransferases, their recombinant expression and uses thereof - Google Patents

Methyltransferases, nucleic acid molecules encoding methyltransferases, their recombinant expression and uses thereof Download PDF

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Publication number
WO2000011142A3
WO2000011142A3 PCT/EP1999/006037 EP9906037W WO0011142A3 WO 2000011142 A3 WO2000011142 A3 WO 2000011142A3 EP 9906037 W EP9906037 W EP 9906037W WO 0011142 A3 WO0011142 A3 WO 0011142A3
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WO
WIPO (PCT)
Prior art keywords
methyltransferases
nucleic acid
acid molecules
molecules encoding
recombinant expression
Prior art date
Application number
PCT/EP1999/006037
Other languages
French (fr)
Other versions
WO2000011142A2 (en
WO2000011142A9 (en
Inventor
Tapani Reinikainen
Antti Nyyssoelae
Janne Kerovuo
Original Assignee
Danisco Finland Oy
Tapani Reinikainen
Antti Nyyssoelae
Janne Kerovuo
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Danisco Finland Oy, Tapani Reinikainen, Antti Nyyssoelae, Janne Kerovuo filed Critical Danisco Finland Oy
Priority to AU57364/99A priority Critical patent/AU5736499A/en
Priority to EP99944425A priority patent/EP1112352A2/en
Publication of WO2000011142A2 publication Critical patent/WO2000011142A2/en
Publication of WO2000011142A3 publication Critical patent/WO2000011142A3/en
Publication of WO2000011142A9 publication Critical patent/WO2000011142A9/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1003—Transferases (2.) transferring one-carbon groups (2.1)
    • C12N9/1007—Methyltransferases (general) (2.1.1.)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

The present invention relates to proteins which are capable of functioning as methyltransferases. More, specifically, the present invention relates to methyltransferases which are capable of carrying out at least one of the following reactions: the conversion of glycine to sarcosine, sarcosine to dimethyl glycine and dimethyl glycine to betaine in the presence of a methyl group donor. Furthermore, the present invention relates to nucleic acid molecules encoding such methyltransferase proteins, recombinant organisms which are capable of expressing said nucleic acids as well as the use of said recombinant organisms.
PCT/EP1999/006037 1998-08-20 1999-08-18 Methyltransferases, nucleic acid molecules encoding methyltransferases, their recombinant expression and uses thereof WO2000011142A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU57364/99A AU5736499A (en) 1998-08-20 1999-08-18 Methyltransferases, nucleic acid molecules encoding methyltransferases, their recombinant expression and uses thereof
EP99944425A EP1112352A2 (en) 1998-08-20 1999-08-18 Methyltransferases, nucleic acid molecules encoding methyltransferases, their recombinant expression and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13743498A 1998-08-20 1998-08-20
US09/137,434 1998-08-20

Publications (3)

Publication Number Publication Date
WO2000011142A2 WO2000011142A2 (en) 2000-03-02
WO2000011142A3 true WO2000011142A3 (en) 2000-06-22
WO2000011142A9 WO2000011142A9 (en) 2000-08-17

Family

ID=22477419

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/006037 WO2000011142A2 (en) 1998-08-20 1999-08-18 Methyltransferases, nucleic acid molecules encoding methyltransferases, their recombinant expression and uses thereof

Country Status (3)

Country Link
EP (1) EP1112352A2 (en)
AU (1) AU5736499A (en)
WO (1) WO2000011142A2 (en)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994013813A1 (en) * 1992-12-09 1994-06-23 Rhone-Poulenc Biochimie Cells with altered betaine catabolism, their preparation and their use, in particular for producing metabolites or enzymes
EP0697462A2 (en) * 1994-07-22 1996-02-21 Oriental Yeast Co., Ltd. Process for producing Glycine-N-Methyl Transferase using recombinant DNA
WO1998026081A1 (en) * 1996-12-09 1998-06-18 Buelow Leif Transgenic plants having increased freezing and choline tolerance

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994013813A1 (en) * 1992-12-09 1994-06-23 Rhone-Poulenc Biochimie Cells with altered betaine catabolism, their preparation and their use, in particular for producing metabolites or enzymes
EP0697462A2 (en) * 1994-07-22 1996-02-21 Oriental Yeast Co., Ltd. Process for producing Glycine-N-Methyl Transferase using recombinant DNA
WO1998026081A1 (en) * 1996-12-09 1998-06-18 Buelow Leif Transgenic plants having increased freezing and choline tolerance

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Derwent World Patents Index; XP002900865 *

Also Published As

Publication number Publication date
EP1112352A2 (en) 2001-07-04
WO2000011142A2 (en) 2000-03-02
AU5736499A (en) 2000-03-14
WO2000011142A9 (en) 2000-08-17

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