WO2000009181A9 - Pistolet applicateur de fluide polyvalent et utilisation en chirurgie - Google Patents

Pistolet applicateur de fluide polyvalent et utilisation en chirurgie

Info

Publication number
WO2000009181A9
WO2000009181A9 PCT/US1999/018319 US9918319W WO0009181A9 WO 2000009181 A9 WO2000009181 A9 WO 2000009181A9 US 9918319 W US9918319 W US 9918319W WO 0009181 A9 WO0009181 A9 WO 0009181A9
Authority
WO
WIPO (PCT)
Prior art keywords
applicator
irrigation
pathway
cannula
gas
Prior art date
Application number
PCT/US1999/018319
Other languages
English (en)
Other versions
WO2000009181A2 (fr
WO2000009181B1 (fr
WO2000009181A3 (fr
Inventor
Gordon Howard Epstein
Original Assignee
Biosurgical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biosurgical Corp filed Critical Biosurgical Corp
Priority to EP99949538A priority Critical patent/EP1124596A4/fr
Priority to AU62387/99A priority patent/AU6238799A/en
Publication of WO2000009181A2 publication Critical patent/WO2000009181A2/fr
Publication of WO2000009181A9 publication Critical patent/WO2000009181A9/fr
Publication of WO2000009181A3 publication Critical patent/WO2000009181A3/fr
Publication of WO2000009181B1 publication Critical patent/WO2000009181B1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/00491—Surgical glue applicators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71—Suction drainage systems
    • A61M1/77—Suction-irrigation systems
    • A61M1/774—Handpieces specially adapted for providing suction as well as irrigation, either simultaneously or independently
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
    • A61B90/40—Apparatus fixed or close to patients specially adapted for providing an aseptic surgical environment
    • A61B2090/401—Apparatus fixed or close to patients specially adapted for providing an aseptic surgical environment using air flow
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/71—Suction drainage systems
    • A61M1/77—Suction-irrigation systems
    • A61M1/772—Suction-irrigation systems operating alternately

Definitions

  • the present invention is directed to an apparatus and process in which the following physical treatments can be applied to tissue or other work surfaces in conjunction with a clinical procedure: suction and blowing; suction, irrigation and blowing: agent application and blowing; suction, agent application and blowing; suction, sealant agent application, blowing and irrigation, to effect hemostasis, close wounds or achieve other therapeutic results.
  • tissue sealants and other biological materials are an important emerging surgical technique, well adapted for the operating room or field environments such as the doctor's office or mobile medical units.
  • application of such sealants while performing or as necessary to perform minimimally evasive surgery reduces or eliminated the traditional problems associated with more evasive types of procedures.
  • Preferred sealants include fibrin sealants which are formed from blood plasma components and comprise, on the one hand, a first component containing fibrinogen and Factor XIII and on the other hand a second component which usually includes thrombin, and calcium ions.
  • the fibrinogen is capable of a polymerizing and being cross-linked to form a solid fibrin clot when the components are mixed.
  • the necessary additional factors to simulate relevant portions of the natural blood coagulation cascade are suitably distributed between the fibrinogen and thrombin components.
  • sealants are highly effective, are biologically degraded without residue and may promote wound healing. Depending upon the potency of the particular formulations employed, coagulation of the sealant may take place very rapidly, yielding a gel within perhaps 10 or 20 seconds after mixing of the two components.
  • Antanavich et al. United States Patent number 5,585,007 whose disclosure and references are hereby incorporated herein by reference thereto, provides an extensive discussion of the literature relating to fibrinogen sealant preparation (column 1, line 20 to column 4, line 62) and applicators column 4 line 62 to column 5, line 14), as well as a bibliography, (columns 6-10) and is a helpful guide to the teachings of prior workers in the field.
  • Tofflemire U.S. patent number 2,812,765 discloses a handheld applicator for selectively dispensing irrigation fluid, air, or other fluids, or suction.
  • Tofflemire provides a frusto-conical valve B rotatable by a knob 1 1 to selectively connect sources of irrigation fluid I, air A or suction S with a tubular tip D.
  • Tofflemire lacks point-of-use flow controls for any of the dispensed fluids and cannot be used for sealant dispensing, as sealant would jam valve B.
  • tip D is excessively elongated, being longer than the body comprised by transverse bar 38 and sheath 43. Such elongation is unwieldy and unsuitable for dispensing a mixed sealant which might set up in the dispensing cannula, tip D.
  • Epstein U.S. patent number 5,266,877 whose disclosure is also incorporated herein by reference, teaches one form of combination hand-held applicator which can dispense a mixed, two-component tissue sealant, discharged from on-board reservoirs, to close wounds and effect hemostasis and which is also furnished with suction means for applying suction from a cannula alongside a sealant dispensing cannula, to treat a work surface.
  • the suction means is connectable with an external vacuum source, such as is commonly available in operating rooms.
  • the parent applications disclose further embodiments of multi-component, mixed sealant applicators provided with a suction-dispensing cannula, which applicators also employ dual acting suction control valves for enhanced suction control and which are able to employ suction for retrograde clearing of sealant clots from the mixed sealant pathway.
  • a blown air or gas stream also has utility in the surgical arena and suitable sources of pressurized gas are commonly available, flow control difficulties, the risk of air embolisms and the specialized utility of an air stream as a treatment fluid at a surgical site, raise considerable difficulties in providing applicators and methods for dispensing an air or gas stream which can safely be used in delicate surgical procedures.
  • the invention provides a controlled blower and blowing method suitable for applying a gas stream to a surgical site which comprises: a blower body connectable with a pressurized gas source; a gas output cannula for directing a dimensionally controlled flow of a suitable treatment gas, for example sterilized air, to a user-selected area of the surgical site; and a user-operable control valve operable to provide a surgically desirable gas flow from the cannula.
  • a blower body connectable with a pressurized gas source
  • a gas output cannula for directing a dimensionally controlled flow of a suitable treatment gas, for example sterilized air, to a user-selected area of the surgical site
  • a user-operable control valve operable to provide a surgically desirable gas flow from the cannula.
  • control valve is a dual-acting control valve which can simultaneously enlarge a gas supply throat from the source and diminish a venting throat to provide a desired output gas flow control, particularly at low pressures and flow rates.
  • the blower is a lightweight, hand-held easily manipulated device which is equipped to provide an additional or alternative fluid or fluids at the work site, for example suction, irrigation or a tissue sealant fluid.
  • additional or alternative fluid or fluids at the work site for example suction, irrigation or a tissue sealant fluid.
  • multiple fluid flows can be selectively dispensed by operation of a simple, manually actuated selector, switch or valve on the blower.
  • both suction and gas flow are available simultaneously, being dispensed from separate cannulas, with the gas dispensing cannula preferably having a dispensing tip retracted distally behind that of the suction cannula, whereby gas can be circulated from the gas- dispensing cannula, to the work surface and withdrawn from same b ⁇ the suction cannula.
  • suction, and gas flow are selected to be dispersed from the same cannula through a manually actuated selection valve while an irrigation fluid is available simultaneously from the other cannula.
  • Other embodiments are directed to: gas flow and tissue sealant being dispersed simultaneously or separately from separate cannulas; suction, tissue sealant and gas flow being dispersed simultaneously or separately from separate or several cannulas; and suction, tissue sealant, gas flow and irrigation fluids being dispersed simultaneously or separately from several cannulas.
  • the sealant is a biological sealant, for example a tissue adhesive, and the area of application is a biological tissue subject to surgery.
  • the sealant components can comprise a first, structural component capable of gelling, and preferably of solidification and a second, activation component which activates such gelling and, optionally, solidification. More preferably, the sealant is a tissue sealant and the first component comprises fibrinogen and the second component comprises, or can generate a fibrinogen activator, especially thrombin or an equivalent thereof.
  • the invention also includes an applicator and method that provides the user with convenient and ergonomic access to an efficient means for providing suction, blowing and or irrigation in addition to or without simultaneously being able to apply mixed sealant components in accordance with the prior applications provides an novel and unique way of advancing this emerging field while also addressing traditional problems encountered in this and related fields.
  • the invention includes, but is not limited to, a novel surgical method of applying sealant to unexposed or internal biological surfaces, e.g. human or animal anatomical surfaces, that are accessible to a remote applicators, such as the ones disclosed in aforementioned patent applications.
  • a remote mixing chamber which receives a flow of multiple sealant components and mixes the sealant components at the distal end of the applicator, allows the distal end of the applicator to apply a mixed sealant a work site.
  • the present invention is also directed to an apparatus an method which includes manipulation of a single device to provide one or more of the following; suction, blowing and/or irrigation, in addition to. or without, simultaneously being able to apply mixed sealant components.
  • Figure 1 is a side perspective view illustrating the first embodiment of the multi-purpose applicator according to the present invention
  • Figure 2 is a longitudinal cross sectional view of the forward nose portion of the Figure 1 embodiment
  • Figure 3 is a longitudinal cross sectional view of the forward nose portion of the Figure 1 embodiment
  • Figure 4 is a side perspective view of an alternative to the Figure 1 embodiment:
  • Figure 5 is a side perspective view illustrating the second embodiment of the multi-purpose applicator according to the present invention
  • Figure 6 is a side perspective view illustrating the third embodiment of the multi-purpose applicator according to the present invention
  • Figure 7 is a side perspective view illustrating the third embodiment of the multi-purpose applicator according to the present invention
  • Figure 8 is a side perspective view illustrating the fourth embodiment of the multi-purpose applicator according to the present invention
  • Figure 9 is a side perspective view illustrating the fifth embodiment of the multi-purpose applicator according to the present invention.
  • Figure 10 is a side perspective view illustrating the fifth embodiment of the multi-purpose applicator according to the present invention.
  • Figure 1 1 is a cross sectional view along lines 1 1-1 1 of Figure 10;
  • Figure 12 is a cross sectional view along lines 12-12 of Figure 10;
  • Figure 13 is a cross sectional view of an alternative embodiment of the present;
  • Figure 14 is a side perspective view illustrating an alternative to Figure 9 embodiment.
  • the present invention is directed to an applicator having among other elements, an applicator assembly which includes a combination of multiple features.
  • One beneficial feature of the current invention is the provision of a sealant application assembly which works in cooperation with an applicator that can conveniently and selectively provide suction or one or more additional fluid outputs, for example, blowing and irrigation.
  • Applicator 10 has a nose portion 12 which communicates with a main body portion 14.
  • Main body portion 14 supplies pressurized air and suction to nose portion 12 for use during a surgical procedure.
  • Suction and air are supplied to an area of application through a pair of cannulas 16 and 18, respectively.
  • Cannulas 16 and 18 extend outwardly from nose portion 12.
  • a pair of supply lines 20 and 22 supply suction and compressed air to cannulas 16 and 18 through a pair of internal conduits 24 and 26.
  • cannula 18 is positioned to be further away from nose portion 12.
  • cannulas 16 and 18 can be the same length.
  • Either cannula 16 and 18 can supply suction or blowing simply by connecting the appropriate supply line.
  • Cannulas 16 and 18 communicate with main body portion 14, and apply suction, and compressed air to the surgical area.
  • a user manipulated control valve 28 allows the user to control the suction or blowing being applied by applicator 10.
  • the gas flow being blown on the work area is useful in many ways. Blowing of the area removes liquids and debris from the area being worked. In addition, blowing may also be used to control or vary the temperature of tissue around the work area.
  • Control valve 28 has a plurality of valve openings 30.
  • a selection valve 32 having an opening 34 is slidably positioned within body portion 14 to provide communication of either supply line 20 or 22 to control valve 28.
  • Selection valve 32 is conveniently located so that it may be manipulated by the thumb of a user as he or she is gripping the device.
  • selection valve 32 is such that the user's thumb can easily manipulate selection valve 32 without the user having to reposition his or her hand on applicator 10.
  • Such ergonomic placement of selection valve 32 is particularly advantageous when applicator 10 is used in surgical applications and the surgeon or operator is relieved of having to continually attend to the instrument being used.
  • selection valve 32 is positioned to allow for communication of supply line 20 with cannula 18.
  • Figure 3 illustrates communication of supply line 22 with cannula 16.
  • Control valve 28 is similar in design to the suction control valve described in the parent patent applications except a dividing wall 36 is positioned to limit the communication of cannulas 16 and 18 with supply lines 20 and 22. (As illustrated in Figures 2 and 3).
  • control valve 28 As the user depresses control valve 28 to the position illustrated in Figure 2 suction through cannula 18 is possible.
  • the suction force can be varied by the user manipulating the position of control valve 28.
  • selection valve 32 is moved to seal supply line 20 and provide access to supply line 22. As control valve 28 is depressed further the suction flow through cannula 18 is cut off and pressurized air is now flowing through cannula 16.
  • Shuttle valve 40 is also similar to the valve disclosed and described in the prior applications.
  • control valve 28 has an opening 38 and, in addition to the repositioning of control valve 28, air flow, either suction or blowing, is further manipulated by the placement of the user's thumb over opening 38.
  • applicator 10 is equipped with a single cannula 16 and a single supply line 20 which can supply suction and/or blowing to cannula 16. As required the user simply removes line 20 and replaces it with a second line that is either supplying compressed air or suction to applicator 10.
  • Line 20 is secured to applicator 10 with a quick release mechanism or the equivalent, such as a spring loaded casing that slides back and forth on the exterior of line 20. This allows line 20 to be quickly removed and replaced.
  • cannula 16 of Figure 4 has an outside diameter of 0.13 inches and an inside diameter of 0.08 inches.
  • applicator 10 is equipped to allow a user to apply suction, irrigation and blowing to an area.
  • line 20 is dedicated to supplying an irrigation fluid directly to cannula 16 while line 22 supplies suction and compressed air to cannula 18.
  • Irrigation fluid is a sterile saline solution, or the equivalent, for use as a means for clearing the area after suction and prior to blowing. It is also anticipated that the order of suction, blowing and irrigation may be varied as conditions so require.
  • line 22 may have two internal lines 22a and 22b, one supplying suction and the other compressed air.
  • a second selection valve 33 is positioned to effect communication of lines 22a and 22b to cannula 18.
  • line 20 can also supply pressurized air to cannula 16.
  • cannula 16 applies a sealant 42 while cannula 18 is connected to supply line which supplies compressed air in the direction of arrows 44.
  • sealant 42 application its mixing, supply, audible indications of sealant component supply and retrograde clearing of coagulated sealant and the component parts therefor are similar to those disclosed in the parent applications. Accordingly, the detailed description of the same is incorporated herein by reference thereto.
  • Compressed air is blown over the area in need of surgical repair, prior to the application of sealant 42, while cannulas 16 and 18 move in the direction of arrow 46.
  • compressed air is blown over the wound area after application of sealant 42.
  • applicator 10 applies a steady stream of compressed air in the direction of arrows 44. As illustrated, compressed air is being applied to recently applied sealant 42. Several passes can be made over the area until sealant 42 is cured.
  • a controlled air stream may also be used to manipulate the temperature of the surrounding tissue. For instance, the pressurized gas being applied may be cooled or heated to provide a corresponding affect to the surrounding tissue.
  • a preferred compressed gas supplied to cannula 18 is a sterile carbon dioxide which because of its high diffusion coefficient dissolves rapidly and may avoid gas embolism which could occur with other gases. Also carbon dioxide is relatively inert chemically. Other sterile gases which may be used include nitrogen, air, enriched air and oxygen. Compressed gas may partially contain, gaseous or liquid medications to control infection or provide other desired therapeutic or conditioning effect. Liquids, or even finely dispersed powders, can, if desired be entrained in the gas as a suspension, for which purpose the liquids should be atomized or sprayed or otherwise distributed in space.
  • cannula 18 is connected to supply lines 20 and 22 each of which supplies either suction or compressed gas. Communication of cannula 18 to supply lines 20 and 22 is effectuated through selection valve 32.
  • the user can first apply suction to the wound area, apply agent 42, manipulated selection valve 32 and then apply compressed air to the applied agent.
  • the user may first apply compressed air, then apply sealant 42 and then apply suction.
  • a third cannula 19 is positioned on nose potion 12.
  • cannulas 18 and 19 communicate directly with supply lines 20 and 22 while cannula 16 is used for dispersment of sealant 42.
  • Valve 32 allows the user to select either suction or blowing of compressed air.
  • dividing wall 36 and openings 30 are appropriately positioned to facilitate such communication.
  • cannula 16 applies agent 42
  • cannula 18 is connected to supply lines 20 and 22, each of which supplies either suction or compressed gas
  • a cannula 19 is directly connected to a third supply line 21 which provides irrigation to cannula 19. Communication of cannulas 18 and 19 to supply lines 20-22 is effectuated through selection valve 32.
  • supply lines 20, 21 and 22 are internally contained within main supply line 48. Each internal supply line is devoted to supplying either suction, compressed air or irrigation fluids to applicator 10. Cannula 18 provides either suction or blowing while cannula 19 is dedicated to supplying irrigation fluids directly supplied to cannula 19.
  • a user can first operate applicator 10 to apply suction to a wound area for removal of unwanted liquids and debris. Suction may also be used to gently grab a piece of tissue and move it to a desired location, such as in a wound closure procedure. Then sealant 42 is applied from applicator 10 to the desired location. Once sealant 42 is applied over the wound, the application device is now configured to applied compressed air over the area of application for drying and liquid and debris removal. As a final step irrigation fluid is now run through area of application.
  • the present invention allows a user to perform this sequence of steps without having to use multiple instruments. Additionally, the applicator 10 is constructed in accordance with the present invention to allow for such manipulation without having the user to reposition their hand.
  • Selection valve 32 is positioned within body portion 14 and controls the switching of supply lines 20, 21 and 22 to the appropriate cannulas.
  • Selection valve 32 has a movable valve member in the form of a disk 50 that is manipulated by the user to select compressed air, suction or irrigation to be supplied to cannulas 18 and 19.
  • Disk 50 is accessible through an opening 52 in body portion 14. Opening 52 is positioned to be easily accessed by the thumb of the user as he or she is gripping the device. Disk 50 is manipulated by rotating it in the directions of arrow 54.
  • Disk 50 has an opening 58. Opening 58 is positioned to selectively provide access to one of internal supply lines 20, 21 and 22. Disk 50 has a plurality of detents 60 along the periphery 56 of disk 50 which, in cooperation with a spring 62, lock disk 50 in positions which align opening 58 with one of supply lines 20, 21 and 22.
  • an improved gripping surface 64 is incorporated into outer periphery 56 of disk 50. (see the dashed lines in Figure 1 1 ).
  • periphery 56 is marked with indicia to indicate which supply line is being accessed. For instance, terms such "AIR”, “SUCTION” and “IRRIGATION” may be printed along periphery 56 of disk 50 and will be visible through opening 52 to indicate the positioning of opening 58. Alternatively, or additionally, periphery 56 of disk 50 may be color coded, or it may be textured or shaped to provide a tactile indication to the user of the selected function.
  • detents 60 are positioned to provide locking positions in which opening 58 only partially aligns with one of the internal supply lines ( Figure 13). Such a configuration allows the user to partially access one of the internal supply lines thereby providing a reduced air or fluid flow while also manipulating the same with control valve 28.
  • line 48 may have more or less than three internal supply lines. Such configurations and variations may be dictated by the intended usage of applicator 10. For instance, an applicator intended primarily for suction and blowing may only require a two line configuration.
  • a single supply line 48 may be equipped with a quick release mechanism, such as spring actuated casing, or the equivalent, typically used in air supply lines. With this configuration the user simply changes the supply line as required.
  • FIG. 14 an alternative embodiment of the present invention is illustrated.
  • component parts performing similar or analogous functions are numbered in multiples of 100.
  • three needle valves 150 are positioned on the exterior of line 148. Valves 150 regulate the air flow and/or irrigation fluid flow of internal supply lines 120, 121 and 122 (not shown).
  • valve 150 may be provided by: a clamp or roller which pinches a flexible tube; needle valves; stop-cock valves; trumpet valves; gate valves; pressure regulators; and other various flow restricting devices.
  • the present invention provides a particularly advantageous method of preparing the area for sealant application.
  • one embodiment that is particularly well suited for use by a surgeon which is comfortable, lightweight and precisely manipulable, has an applicator body length (with tip removed) of about 15 cm (about 6 inches) and a length of reservoir within each syringe of about 5.5 cm (about 2V ⁇ inches).
  • an applicator body length with tip removed
  • a length of reservoir within each syringe of about 5.5 cm (about 2V ⁇ inches).
  • an applicator body length with tip removed
  • a length of reservoir within each syringe of about 5.5 cm (about 2V ⁇ inches).
  • a reservoir capacity of about 3 cc With circular cylindrical reservoirs, in syringes 12, of approximately 0.9 cm ( 3 /a inch) diameter a reservoir capacity of about 3 cc, each, total 6 cc with two reservoirs, is provided.
  • a preferred length for cannulas 16, 18 and 1 18 when embodied in an applicator of such proportions is less than about 5 cm.
  • cannulas 16, 18 and 1 18 are preferably much shorter than the body of the applicator, and the distance any mixed sealant travels (if such is employed) from the point of mixing is relatively short, preferably not more than about 5 cm or more preferably no more than about 3 cm.
  • Such dimensions as these provide an applicator which is comfortable and ergonomic for most surgeons to use with precision.
  • Preferred constructions may vary these dimensions by up to about 10, or less preferably 20 percent. Less demanding applications may vary the given or corresponding dimensions by up to about 50 percent while still providing an applicator that can be supported and comfortably manipulated in one hand.
  • blowing of a sterile and preferably inert gas can be used for clearing away of fluids such as blood during surgery to enhance visibility and access to the surgical site.
  • surgical agents such as fibrin sealant
  • Blowing of a sterile gas can be used for this purpose, either with constant or variably controlled fiow. Drying of a surface is also important to promote adhesion or hemostasis prior to application of a sealant. Drying can be attained using blowing. Delivery of gaseous surgical agents or liquid agents which can be suspended in a gas can be facilitated by a blowing device.

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Surgical Instruments (AREA)
  • Application Of Or Painting With Fluid Materials (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Nozzles (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

La présente invention concerne des pistolets applicateurs polyvalents de fluides, en pensant plus particulièrement aux utilisations chirurgicales. Ces pistolets sont conçus spécifiquement pour effectuer la distribution de diverses combinaisons de gaz pressurisés stériles, mais aussi pour réaliser des aspirations, des irrigations et des occlusions. Ces pistolets sont même capables de distribuer un mélange liquide occlusif. Les réalisations préférées comportent une valve à double effet qui permet de commander sélectivement une arrivée de gaz ou une aspiration. Cette valve permet de commander un débit alimenté depuis une source, et ce, tout en réalisant une reprise de mise à l'atmosphère de ce débit.
PCT/US1999/018319 1998-08-13 1999-08-12 Pistolet applicateur de fluide polyvalent et utilisation en chirurgie WO2000009181A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP99949538A EP1124596A4 (fr) 1998-08-13 1999-08-12 Pistolet applicateur de fluide polyvalent et utilisation en chirurgie
AU62387/99A AU6238799A (en) 1998-08-13 1999-08-12 Multipurpose fluid applicator and method, with surgical uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9639498P 1998-08-13 1998-08-13
US60/096,394 1998-08-13

Publications (4)

Publication Number Publication Date
WO2000009181A2 WO2000009181A2 (fr) 2000-02-24
WO2000009181A9 true WO2000009181A9 (fr) 2000-05-18
WO2000009181A3 WO2000009181A3 (fr) 2000-07-06
WO2000009181B1 WO2000009181B1 (fr) 2000-09-08

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/018319 WO2000009181A2 (fr) 1998-08-13 1999-08-12 Pistolet applicateur de fluide polyvalent et utilisation en chirurgie

Country Status (3)

Country Link
EP (1) EP1124596A4 (fr)
AU (1) AU6238799A (fr)
WO (1) WO2000009181A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010070387A1 (fr) * 2008-12-19 2010-06-24 Michela Facco Dispositif chirurgical pour nettoyage de plaies et de sites chirurgicaux
WO2011113978A2 (fr) * 2010-03-18 2011-09-22 Marquez Canada Juan Système de thérapie de vide utilisé pour traiter des lésions complexes

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1987907A (en) * 1929-11-22 1935-01-15 Joseph B Jenkins Combination surgical air-blast and suction tip
US2812765A (en) 1955-12-19 1957-11-12 Benjamin F Tofflemire Combination aspirator and fluiddelivering surgical instrument
US5226877A (en) * 1989-06-23 1993-07-13 Epstein Gordon H Method and apparatus for preparing fibrinogen adhesive from whole blood
JPH03100807A (ja) 1989-09-14 1991-04-25 Hitachi Ltd 対話型実装機ｎｃデータ作成装置
US5585007A (en) 1994-12-07 1996-12-17 Plasmaseal Corporation Plasma concentrate and tissue sealant methods and apparatuses for making concentrated plasma and/or tissue sealant
US5902264A (en) * 1996-04-26 1999-05-11 United States Surgical Corporation Endoscopic surgical instrument for aspiration and irrigation

Also Published As

Publication number Publication date
EP1124596A4 (fr) 2005-05-04
WO2000009181A2 (fr) 2000-02-24
AU6238799A (en) 2000-03-06
WO2000009181B1 (fr) 2000-09-08
WO2000009181A3 (fr) 2000-07-06
EP1124596A2 (fr) 2001-08-22

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