WO2000008145A3 - Nouveaux genes de regulation de l'hematopoiese - Google Patents

Nouveaux genes de regulation de l'hematopoiese Download PDF

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Publication number
WO2000008145A3
WO2000008145A3 PCT/EP1999/005566 EP9905566W WO0008145A3 WO 2000008145 A3 WO2000008145 A3 WO 2000008145A3 EP 9905566 W EP9905566 W EP 9905566W WO 0008145 A3 WO0008145 A3 WO 0008145A3
Authority
WO
WIPO (PCT)
Prior art keywords
scm
hematopoiesis
control
novel genes
genes
Prior art date
Application number
PCT/EP1999/005566
Other languages
English (en)
Other versions
WO2000008145A2 (fr
Inventor
Michael Paul Cooke
Claire Louise Holness
Oksana Ivanivna Sirenko
Original Assignee
Novartis Ag
Novartis Erfind Verwalt Gmbh
Michael Paul Cooke
Claire Louise Holness
Oksana Ivanivna Sirenko
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novartis Ag, Novartis Erfind Verwalt Gmbh, Michael Paul Cooke, Claire Louise Holness, Oksana Ivanivna Sirenko filed Critical Novartis Ag
Priority to JP2000563772A priority Critical patent/JP2002524040A/ja
Priority to CA002337904A priority patent/CA2337904A1/fr
Priority to EP99944319A priority patent/EP1100914A2/fr
Priority to AU57300/99A priority patent/AU5730099A/en
Publication of WO2000008145A2 publication Critical patent/WO2000008145A2/fr
Publication of WO2000008145A3 publication Critical patent/WO2000008145A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

La présente invention concerne trois nouveaux gènes HSC appelés SCM 3, SCM 26 et SCM 113, leurs zones de codage, les produits géniques, des applications des ces gènes, des produits de synthèse d'ADN, des vecteurs et des cellules modifiées comprenant chacune le gène en question ou un fragment de celui-ci. Par ailleurs, cette invention concerne des procédés d'utilisation des séquences polynucléotidiques et polypeptidiques des SCM 3, SCM 26, et SCM 113.
PCT/EP1999/005566 1998-08-03 1999-08-02 Nouveaux genes de regulation de l'hematopoiese WO2000008145A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2000563772A JP2002524040A (ja) 1998-08-03 1999-08-02 造血の制御における新規遺伝子
CA002337904A CA2337904A1 (fr) 1998-08-03 1999-08-02 Nouveaux genes de regulation de l'hematopoiese
EP99944319A EP1100914A2 (fr) 1998-08-03 1999-08-02 Nouveaux genes de regulation de l'hematopoiese
AU57300/99A AU5730099A (en) 1998-08-03 1999-08-02 Novel genes in control of hematopoiesis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12831098A 1998-08-03 1998-08-03
US09/128,310 1998-08-03

Publications (2)

Publication Number Publication Date
WO2000008145A2 WO2000008145A2 (fr) 2000-02-17
WO2000008145A3 true WO2000008145A3 (fr) 2000-06-29

Family

ID=22434708

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/005566 WO2000008145A2 (fr) 1998-08-03 1999-08-02 Nouveaux genes de regulation de l'hematopoiese

Country Status (5)

Country Link
EP (1) EP1100914A2 (fr)
JP (1) JP2002524040A (fr)
AU (1) AU5730099A (fr)
CA (1) CA2337904A1 (fr)
WO (1) WO2000008145A2 (fr)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000073454A1 (fr) * 1999-06-02 2000-12-07 Genentech, Inc. Polypeptides transmembranaires secretes et acides nucleiques codants pour ceux-ci
US20020132253A1 (en) 1997-06-16 2002-09-19 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20020172678A1 (en) 2000-06-23 2002-11-21 Napoleone Ferrara EG-VEGF nucleic acids and polypeptides and methods of use
US7264801B2 (en) 1998-08-11 2007-09-04 Genentech, Inc. EG-VEGF nucleic acids and polypeptides and method of use
US20030003507A1 (en) 1999-06-02 2003-01-02 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998012306A1 (fr) * 1996-09-23 1998-03-26 Ontogeny, Inc. Cellules souches hematopoietiques et procedes relatifs a leur production
WO1998039448A2 (fr) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 186 nouvelles proteines secretees
WO1998042741A2 (fr) * 1997-03-25 1998-10-01 Genetics Institute, Inc. Proteines secretees et polynucleotides les codant
WO1998045436A2 (fr) * 1997-04-10 1998-10-15 Genetics Institute, Inc. Marqueurs secretes de sequence exprimee (sest)

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998012306A1 (fr) * 1996-09-23 1998-03-26 Ontogeny, Inc. Cellules souches hematopoietiques et procedes relatifs a leur production
WO1998039448A2 (fr) * 1997-03-07 1998-09-11 Human Genome Sciences, Inc. 186 nouvelles proteines secretees
WO1998042741A2 (fr) * 1997-03-25 1998-10-01 Genetics Institute, Inc. Proteines secretees et polynucleotides les codant
WO1998045436A2 (fr) * 1997-04-10 1998-10-15 Genetics Institute, Inc. Marqueurs secretes de sequence exprimee (sest)

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE EMEST29 E.M.B.L. Databases; 15 December 1996 (1996-12-15), HILLIER L ET AL: "Homo sapiens cDNA clone 491654 5'", XP002130036 *

Also Published As

Publication number Publication date
WO2000008145A2 (fr) 2000-02-17
CA2337904A1 (fr) 2000-02-17
JP2002524040A (ja) 2002-08-06
AU5730099A (en) 2000-02-28
EP1100914A2 (fr) 2001-05-23

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