WO2000007648A1 - Prefilled syringe with means for preventing plunger removal - Google Patents

Prefilled syringe with means for preventing plunger removal Download PDF

Info

Publication number
WO2000007648A1
WO2000007648A1 PCT/US1999/017773 US9917773W WO0007648A1 WO 2000007648 A1 WO2000007648 A1 WO 2000007648A1 US 9917773 W US9917773 W US 9917773W WO 0007648 A1 WO0007648 A1 WO 0007648A1
Authority
WO
WIPO (PCT)
Prior art keywords
plunger
finger grip
aperture
vial
rod
Prior art date
Application number
PCT/US1999/017773
Other languages
French (fr)
Other versions
WO2000007648A9 (en
WO2000007648B1 (en
Inventor
John W. Pellow
Original Assignee
Schott Pharmaceutical Packaging, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schott Pharmaceutical Packaging, Inc. filed Critical Schott Pharmaceutical Packaging, Inc.
Priority to AU54669/99A priority Critical patent/AU5466999A/en
Priority to EP99940909A priority patent/EP1042022A1/en
Publication of WO2000007648A1 publication Critical patent/WO2000007648A1/en
Publication of WO2000007648B1 publication Critical patent/WO2000007648B1/en
Publication of WO2000007648A9 publication Critical patent/WO2000007648A9/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A61M2005/3139—Finger grips not integrally formed with the syringe barrel, e.g. using adapter with finger grips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31501—Means for blocking or restricting the movement of the rod or piston
    • A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit

Definitions

  • the present invention generally relates to syringes of a type having one end of a vial closed by a plunger.
  • the present invention relates more specifically to prefilled syringes of a type that combines the syringe vial or body, that is closed at one end by a membrane and closed at the other end by a plunger, with a cannula hub or a finger grip at a respective end thereof.
  • Syringes which would benefit from the present invention are known in the prior art as exemplified by U.S. Patent 5,067,947, which is incorporated herein as if fully set forth.
  • the present invention provides a finger grip that prevents unintended removal of the plunger from a syringe vial upon retraction of the plunger rod.
  • the present invention also provides a finger grip that is less likely to be dislodged from the vial.
  • Figure 1 illustrates the structural components of a prior art syringe that benefits from the present invention.
  • Figure 2 shows a syringe of the type shown in Figure 1 that incorporates the present invention.
  • Figure 3 shows the syringe of Figure 2 with the plunger in the fully withdrawn position.
  • Figure 4 is an exploded view of the encircled area of
  • the syringe 10 includes a glass vial or cartridge body 11 which has a finger grip 13 mounted on one end and a hub 15 for mounting a needle 17 on the other end.
  • the needle 17 will have a needle shield 19.
  • the hub 15 might include a uer cap and Luer lock connection.
  • the end of the vial 11 having the hub 15 is sealed prior to use.
  • the contents 25 are retained in the vial 11 by a plunger 27 which effectively seals that end of the vial 11.
  • the plunger 27 has female threads 29 for engagement with the male threads 23 of the plunger rod 21.
  • the finger grip 13 is slidably mounted onto the vial 11 by a base 31 which terminates in a ring 32 that limits movement of the finger grip 13 along the vial 11.
  • the needle hub means 15, which mounts the needle 17 has a larger skirt 33 which surrounds the vial 11.
  • the vial engaging portion 35 of hub 15 is sized to engage the metal cap 37 which secures the end seal to the vial 11. Syringes of this type are available from Schott Pharmaceutical Packaging, Inc., of Cleona, PA 17042.
  • Figure 4 is a greatly enlarged sectional view of the encircled area of Figure 3.
  • the ring 40 of finger grip 13 defines an aperture 42 that is approximately equal to the exterior dimension of the plunger rod 21 and less than the interior diameter of the vial 11.
  • the aperture 42 need only be of diameter to permit the plunger rod 21 to be assembled to the plunger.
  • the aperture must be such that the threaded portion 23 of the plunger rod 21 will pass through the aperture 42 and the rod 21 can be rotated to fasten the threads 23 and 29.
  • Such an aperture 42 will be sufficiently large to permit insertion of the plunger 21 into the vial 11 during movement of the plunger 27.
  • aperture 42 is dimensioned to clearly extend beyond the interior of vial 11 so as to create the barrier 44 which blocks egress of the plunger 27.
  • ring 40 is not in direct contact with the plunger rod 21.
  • barrier 44 will always extend beyond the interior of vial 11.
  • the portion of ring 40 that defines the aperture include an inwardly tapered edge 48 that results in a slightly reduced ring dimension adjacent to the plunger 27. This permits the upper edge of the tapered threaded cylinder to flex outwardly and release the threads 23 of rod 21 from their mate with the threads 29. As a result, withdrawal of the plunger rod 21 to its rear most position will encourage outward deflection that will release the plunger rod 21 from the plunger 27 and allow rod 21 to be withdrawn while maintaining the plunger 27 in the vial 11.
  • the threaded portions 23 and 29 have complementary tapers of about five degrees (5°).
  • the plunger rod 21 is mated to the plunger 27 with only sufficient interconnection security for exerting the force required to retract the plunger 27 through vial 11. This force is well below that which required to dislodge the finger grip 13 from the vial 11.
  • the combination of outward deflection and thread tapers allows dislodgment of the plunger rod 21 from plunger 27 but avoiding damage to the overall syringe resulting from plunger extraction or damage to the finger grip-vial interface as a result of excess mating force.
  • a plunger 27 fabricated from a material having a Shore A durometer of 50 has been found to be satisfactory to meet these conditions .
  • an additional feature of the present invention is the provision of an extended or extra long plunger rod 21.
  • the present invention facilitates better user finger location and increases the user's control over the plunger rod 21 during retraction of the plunger 27.

Landscapes

  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

A finger grip (13) that prevents unintended removal of the plunger (27) from a syringe vial (11) upon retraction of the plunger rod (21).

Description

PREFILLED SYRINGE WITH MEANS FOR PREVENTING PLUNGER REMOVAL
BACKGROUND OF THE INVENTION
The present invention generally relates to syringes of a type having one end of a vial closed by a plunger. The present invention relates more specifically to prefilled syringes of a type that combines the syringe vial or body, that is closed at one end by a membrane and closed at the other end by a plunger, with a cannula hub or a finger grip at a respective end thereof. Syringes which would benefit from the present invention are known in the prior art as exemplified by U.S. Patent 5,067,947, which is incorporated herein as if fully set forth.
SUMMARY OF THE INVENTION The present invention provides a finger grip that prevents unintended removal of the plunger from a syringe vial upon retraction of the plunger rod. The present invention also provides a finger grip that is less likely to be dislodged from the vial.
BRIEF DESCRIPTION OF THE DRAWINGS
Figure 1 illustrates the structural components of a prior art syringe that benefits from the present invention.
Figure 2 shows a syringe of the type shown in Figure 1 that incorporates the present invention. Figure 3 shows the syringe of Figure 2 with the plunger in the fully withdrawn position. Figure 4 is an exploded view of the encircled area of
Figure 3.
DESCRIPTION OF THE PREFERRED EMBODIMENT
The preferred embodiment of the invention will be described with reference to the drawing figures wherein like numerals identify like elements.
A syringe combination which will benefit from the present invention is shown, in section, in Figure 1. The syringe 10 includes a glass vial or cartridge body 11 which has a finger grip 13 mounted on one end and a hub 15 for mounting a needle 17 on the other end. Typically, the needle 17 will have a needle shield 19. Alternatively, the hub 15 might include a uer cap and Luer lock connection. The end of the vial 11 having the hub 15 is sealed prior to use. The contents 25 are retained in the vial 11 by a plunger 27 which effectively seals that end of the vial 11. The plunger 27 has female threads 29 for engagement with the male threads 23 of the plunger rod 21. The finger grip 13 is slidably mounted onto the vial 11 by a base 31 which terminates in a ring 32 that limits movement of the finger grip 13 along the vial 11. At the other end of the vial 11, the needle hub means 15, which mounts the needle 17, has a larger skirt 33 which surrounds the vial 11. The vial engaging portion 35 of hub 15 is sized to engage the metal cap 37 which secures the end seal to the vial 11. Syringes of this type are available from Schott Pharmaceutical Packaging, Inc., of Cleona, PA 17042. Since use of the syringe 10 may occasionally require emptying the contents thereof for mixing with other medications or carrier media and then refilling the syringe, there exist a potential for excessive withdrawal of the plunger rod 21 that may result in displacement or removal of the plunger 27. This potentially exists in the current configuration because the ring 32 typically has an interior diameter that is no less than the interior diameter of the vial 11. In the past this has been sufficient for purposes of locating the finger grip, however, it did not prevent unintended withdrawal of the plunger 27.
The invention will be appreciated more fully by reference to Figure 4 which is a greatly enlarged sectional view of the encircled area of Figure 3. As can be seen with reference to Figure 4, the ring 40 of finger grip 13 defines an aperture 42 that is approximately equal to the exterior dimension of the plunger rod 21 and less than the interior diameter of the vial 11. Generally speaking, the aperture 42 need only be of diameter to permit the plunger rod 21 to be assembled to the plunger. In the present case, the aperture must be such that the threaded portion 23 of the plunger rod 21 will pass through the aperture 42 and the rod 21 can be rotated to fasten the threads 23 and 29. Such an aperture 42 will be sufficiently large to permit insertion of the plunger 21 into the vial 11 during movement of the plunger 27.
Preferably, aperture 42 is dimensioned to clearly extend beyond the interior of vial 11 so as to create the barrier 44 which blocks egress of the plunger 27. Preferably, ring 40 is not in direct contact with the plunger rod 21. In any event, barrier 44 will always extend beyond the interior of vial 11. It is also preferred that the portion of ring 40 that defines the aperture include an inwardly tapered edge 48 that results in a slightly reduced ring dimension adjacent to the plunger 27. This permits the upper edge of the tapered threaded cylinder to flex outwardly and release the threads 23 of rod 21 from their mate with the threads 29. As a result, withdrawal of the plunger rod 21 to its rear most position will encourage outward deflection that will release the plunger rod 21 from the plunger 27 and allow rod 21 to be withdrawn while maintaining the plunger 27 in the vial 11.
As can be seen from Figure 4, the threaded portions 23 and 29 have complementary tapers of about five degrees (5°). The plunger rod 21 is mated to the plunger 27 with only sufficient interconnection security for exerting the force required to retract the plunger 27 through vial 11. This force is well below that which required to dislodge the finger grip 13 from the vial 11. The combination of outward deflection and thread tapers allows dislodgment of the plunger rod 21 from plunger 27 but avoiding damage to the overall syringe resulting from plunger extraction or damage to the finger grip-vial interface as a result of excess mating force. A plunger 27 fabricated from a material having a Shore A durometer of 50 has been found to be satisfactory to meet these conditions .
Referring again to Figure 2, an additional feature of the present invention is the provision of an extended or extra long plunger rod 21. By providing additional length on the plunger rod so it extends above the finger grip 13, when the plunger 27 is fully inserted, the present invention facilitates better user finger location and increases the user's control over the plunger rod 21 during retraction of the plunger 27.

Claims

What is claimed is:
1. A finger grip for a syringe of a type having an open ended vial of a predetermined interior dimension that has a first end closed by a plunger that is movable through the syringe body toward a second end, the first end being further closed by a finger grip which defines an aperture that is in axial alignment with the plunger and permits a plunger rod to pass through to the plunger, the finger grip characterized by: a defined aperture dimension that is greater than that of the plunger rod and less than that of the plunger.
2. The finger grip of claim 1 wherein: the portion thereof that defines the aperture tapers inwardly from the vial so as to define a larger aperture in the direction of the plunger.
3. The combination of a prefilled syringe of a type having an open ended vial of a predetermined interior dimension that is closed at one end by a movable plunger with an outwardly facing mating portion and a finger grip that defines an aperture that is in axial alignment with the plunger mating portion and of an interior dimension that passes a plunger rod with a complementary mating portion to the plunger's mating portion for engagement therewith, the combination characterized by: the finger grip aperture being of dimension that permits passage of the plunger rod therethrough but prevents passage of the plunger therethrough.
4. The combination of claim 3 wherein in the mate between the plunger and the rod is severed by abutment with the finger grip that defines the aperture and the finger grip remains attached to the vial .
PCT/US1999/017773 1998-08-06 1999-08-06 Prefilled syringe with means for preventing plunger removal WO2000007648A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU54669/99A AU5466999A (en) 1998-08-06 1999-08-06 Prefilled syringe with means for preventing plunger removal
EP99940909A EP1042022A1 (en) 1998-08-06 1999-08-06 Prefilled syringe with means for preventing plunger removal

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US9554298P 1998-08-06 1998-08-06
US60/095,542 1998-08-06

Publications (3)

Publication Number Publication Date
WO2000007648A1 true WO2000007648A1 (en) 2000-02-17
WO2000007648B1 WO2000007648B1 (en) 2000-03-23
WO2000007648A9 WO2000007648A9 (en) 2000-11-16

Family

ID=22252486

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/017773 WO2000007648A1 (en) 1998-08-06 1999-08-06 Prefilled syringe with means for preventing plunger removal

Country Status (3)

Country Link
EP (1) EP1042022A1 (en)
AU (1) AU5466999A (en)
WO (1) WO2000007648A1 (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7951120B2 (en) 2003-06-04 2011-05-31 Schott Ag Method for manufacturing a syringe
US20140339776A1 (en) * 2013-05-15 2014-11-20 Sumitomo Rubber Industries, Ltd. Medical gasket
JP2017164219A (en) * 2016-03-15 2017-09-21 住友ゴム工業株式会社 Medical syringe and gasket to be applied to syringe, and use method of syringe

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR399601A0 (en) 2001-03-27 2001-04-26 Silverbrook Research Pty. Ltd. An apparatus and method(ART108)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2854975A (en) * 1952-08-07 1958-10-07 Miljam Instr Corp Hypodermic syringe
US3811441A (en) * 1972-02-10 1974-05-21 Survival Technology Cartridge syringe
US4129130A (en) * 1975-11-05 1978-12-12 Federico Bigarella Vial-syringe
US5067947A (en) 1989-07-18 1991-11-26 Tri/West Systems, Inc. Syringe plunger rod mount
US5700247A (en) * 1995-09-22 1997-12-23 Becton Dickinson France S.A. Backstop device for a flangeless syringe

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2854975A (en) * 1952-08-07 1958-10-07 Miljam Instr Corp Hypodermic syringe
US3811441A (en) * 1972-02-10 1974-05-21 Survival Technology Cartridge syringe
US4129130A (en) * 1975-11-05 1978-12-12 Federico Bigarella Vial-syringe
US5067947A (en) 1989-07-18 1991-11-26 Tri/West Systems, Inc. Syringe plunger rod mount
US5700247A (en) * 1995-09-22 1997-12-23 Becton Dickinson France S.A. Backstop device for a flangeless syringe

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7951120B2 (en) 2003-06-04 2011-05-31 Schott Ag Method for manufacturing a syringe
US20140339776A1 (en) * 2013-05-15 2014-11-20 Sumitomo Rubber Industries, Ltd. Medical gasket
CN104162210A (en) * 2013-05-15 2014-11-26 住友橡胶工业株式会社 Medical gasket
JP2014223150A (en) * 2013-05-15 2014-12-04 住友ゴム工業株式会社 Gasket for medical treatment
EP2803377B1 (en) * 2013-05-15 2022-07-06 Sumitomo Rubber Industries, Ltd. A combination of a medical gasket and a plunger for a prefilled syringe
JP2017164219A (en) * 2016-03-15 2017-09-21 住友ゴム工業株式会社 Medical syringe and gasket to be applied to syringe, and use method of syringe
CN107185082A (en) * 2016-03-15 2017-09-22 住友橡胶工业株式会社 Laminate gasket, medical syringe and its application method

Also Published As

Publication number Publication date
AU5466999A (en) 2000-02-28
WO2000007648A9 (en) 2000-11-16
WO2000007648B1 (en) 2000-03-23
EP1042022A1 (en) 2000-10-11

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