WO2000006731A3 - Persephin arf, a protein encoded by unspliced persephin mrna - Google Patents

Persephin arf, a protein encoded by unspliced persephin mrna Download PDF

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Publication number
WO2000006731A3
WO2000006731A3 PCT/US1999/017277 US9917277W WO0006731A3 WO 2000006731 A3 WO2000006731 A3 WO 2000006731A3 US 9917277 W US9917277 W US 9917277W WO 0006731 A3 WO0006731 A3 WO 0006731A3
Authority
WO
WIPO (PCT)
Prior art keywords
persephin
unspliced
arf
mrna
protein encoded
Prior art date
Application number
PCT/US1999/017277
Other languages
French (fr)
Other versions
WO2000006731A2 (en
Inventor
Eugene M Johnson Jr
Jeffrey D Milbrandt
Paul T Kotzbauer
Patricia A Lampe
Robert Klein
Sauvage Fred De
Original Assignee
Univ Washington
Genentech Inc
Eugene M Johnson Jr
Jeffrey D Milbrandt
Paul T Kotzbauer
Patricia A Lampe
Robert Klein
Sauvage Fred De
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Washington, Genentech Inc, Eugene M Johnson Jr, Jeffrey D Milbrandt, Paul T Kotzbauer, Patricia A Lampe, Robert Klein, Sauvage Fred De filed Critical Univ Washington
Priority to AU52441/99A priority Critical patent/AU5244199A/en
Publication of WO2000006731A2 publication Critical patent/WO2000006731A2/en
Publication of WO2000006731A3 publication Critical patent/WO2000006731A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

A novel protein, persephinARF is disclosed and the human, mouse and rat amino acid sequences thereof are identified. Nucleotide sequences encoding these persephinARF amino acid sequences are also disclosed.
PCT/US1999/017277 1998-07-31 1999-07-30 PERSEPHIN ARF, A PROTEIN ENCODED BY UNSPLICED PERSEPHIN mRNA WO2000006731A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU52441/99A AU5244199A (en) 1998-07-31 1999-07-30 Persephin arf, a protein encoded by unspliced persephin mrna

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12679998A 1998-07-31 1998-07-31
US09/126,799 1998-07-31

Publications (2)

Publication Number Publication Date
WO2000006731A2 WO2000006731A2 (en) 2000-02-10
WO2000006731A3 true WO2000006731A3 (en) 2000-08-03

Family

ID=22426734

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/017277 WO2000006731A2 (en) 1998-07-31 1999-07-30 PERSEPHIN ARF, A PROTEIN ENCODED BY UNSPLICED PERSEPHIN mRNA

Country Status (2)

Country Link
AU (1) AU5244199A (en)
WO (1) WO2000006731A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6222022B1 (en) * 1996-03-14 2001-04-24 Washington University Persephin and related growth factors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033911A1 (en) * 1996-03-14 1997-09-18 Washington University Persephin and related growth factors
WO1999014235A1 (en) * 1997-09-16 1999-03-25 Washington University Persephin and related growth factors

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997033911A1 (en) * 1996-03-14 1997-09-18 Washington University Persephin and related growth factors
WO1999014235A1 (en) * 1997-09-16 1999-03-25 Washington University Persephin and related growth factors

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MILBRANDT ET AL.: "Persephin, a novel neurotrophic factor related to GDNF and Neurturin", NEURON, vol. 20, February 1998 (1998-02-01), pages 245 - 253, XP000892136 *
MILLBRANDT ET AL.: "Homo sapiens persephin mRNA, complete cds.", EMBL DATABASE ACC. NO.: AF040962, 13 March 1998 (1998-03-13), XP002136488 *
TRUPP M ET AL: "PERIPHERAL EXPRESSION AND BIOLOGICAL ACTIVITIES OF GDNF, A NEW NEUROTROPHIC FACTOR FOR AVIAN AND MAMMALIAN PERIPHERAL NEURONS", THE JOURNAL OF CELL BIOLOGY,US,ROCKEFELLER UNIVERSITY PRESS, vol. 130, no. 1, July 1995 (1995-07-01), pages 137 - 148, XP002915840, ISSN: 0021-9525 *

Also Published As

Publication number Publication date
WO2000006731A2 (en) 2000-02-10
AU5244199A (en) 2000-02-21

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