WO1999061909A3 - Methods and compositions for the detection of human herpesvirus - Google Patents

Methods and compositions for the detection of human herpesvirus Download PDF

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Publication number
WO1999061909A3
WO1999061909A3 PCT/US1999/011407 US9911407W WO9961909A3 WO 1999061909 A3 WO1999061909 A3 WO 1999061909A3 US 9911407 W US9911407 W US 9911407W WO 9961909 A3 WO9961909 A3 WO 9961909A3
Authority
WO
WIPO (PCT)
Prior art keywords
detection
compositions
methods
human herpesvirus
sensitive
Prior art date
Application number
PCT/US1999/011407
Other languages
French (fr)
Other versions
WO1999061909A2 (en
Inventor
Chou-Pong Pau
Original Assignee
Us Health
Pau Chou Pong
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Us Health, Pau Chou Pong filed Critical Us Health
Priority to AU40958/99A priority Critical patent/AU4095899A/en
Publication of WO1999061909A2 publication Critical patent/WO1999061909A2/en
Publication of WO1999061909A3 publication Critical patent/WO1999061909A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/081—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from DNA viruses
    • C07K16/085—Herpetoviridae, e.g. pseudorabies virus, Epstein-Barr virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983—Viruses
    • G01N33/56994—Herpetoviridae, e.g. cytomegalovirus, Epstein-Barr virus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16211—Lymphocryptovirus, e.g. human herpesvirus 4, Epstein-Barr Virus
    • C12N2710/16222—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16411—Rhadinovirus, e.g. human herpesvirus 8
    • C12N2710/16422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/005—Assays involving biological materials from specific organisms or of a specific nature from viruses
    • G01N2333/01—DNA viruses
    • G01N2333/03—Herpetoviridae, e.g. pseudorabies virus
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Abstract

Compositions and methods for the detection and diagnosis of infectious diseases are provided. In particular, efficient and sensitive compositions and methods for the detection of human herpesvirus 8 are provided. The claimed diagnostic compositions and methods involve the use of peptides representative of dominant antigenic regions of human herpesvirus in detection assays. Such assays are highly specific, sensitive and accurate.
PCT/US1999/011407 1998-05-26 1999-05-26 Methods and compositions for the detection of human herpesvirus WO1999061909A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU40958/99A AU4095899A (en) 1998-05-26 1999-05-26 Methods and compositions for the detection of human herpesvirus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8669598P 1998-05-26 1998-05-26
US60/086,695 1998-05-26

Publications (2)

Publication Number Publication Date
WO1999061909A2 WO1999061909A2 (en) 1999-12-02
WO1999061909A3 true WO1999061909A3 (en) 2000-03-23

Family

ID=22200268

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/011407 WO1999061909A2 (en) 1998-05-26 1999-05-26 Methods and compositions for the detection of human herpesvirus

Country Status (2)

Country Link
AU (1) AU4095899A (en)
WO (1) WO1999061909A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2445309A1 (en) * 2001-04-24 2002-11-07 Otsuka Pharmaceutical Co., Ltd. Crohn's disease antibody-binding peptide and method of examining crohn's disease
WO2009020628A1 (en) * 2007-08-06 2009-02-12 Epiphany Biosciences, Inc. Diagnosis of kaposi's sarcoma-associated herpesvirus (kshv) infection
US8951723B2 (en) 2009-02-12 2015-02-10 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Serological screening for HHV-8 infection using antigen mixtures

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997024057A2 (en) * 1995-12-27 1997-07-10 Yale University Screening tests for lytic cycle antigens and antibodies to kaposi's sarcoma-associated herpesvirus
WO1997026373A1 (en) * 1996-01-16 1997-07-24 The University Of Michigan Isolation and propagation of a human herpesvirus derived from aids-associated kaposi's sarcoma cells
WO1998003657A1 (en) * 1996-07-19 1998-01-29 Dade Behring Marburg Gmbh Viral interleukin-6
WO1998004576A1 (en) * 1996-07-25 1998-02-05 The Trustees Of Columbia University In The City Of New York Unique associated kaposi's sarcoma virus sequences and uses thereof
WO1998011132A1 (en) * 1996-09-10 1998-03-19 The University Of Liverpool An immunogenic determinant for use in the diagnosis of kaposi's sarcoma
EP0893504A1 (en) * 1997-07-11 1999-01-27 Biotest AG Polypeptide coded by the Kaposi sarcoma-associated virus (KSHV, HHV-8) and its uses in diagnostic and therapy

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997024057A2 (en) * 1995-12-27 1997-07-10 Yale University Screening tests for lytic cycle antigens and antibodies to kaposi's sarcoma-associated herpesvirus
WO1997026373A1 (en) * 1996-01-16 1997-07-24 The University Of Michigan Isolation and propagation of a human herpesvirus derived from aids-associated kaposi's sarcoma cells
WO1998003657A1 (en) * 1996-07-19 1998-01-29 Dade Behring Marburg Gmbh Viral interleukin-6
WO1998004576A1 (en) * 1996-07-25 1998-02-05 The Trustees Of Columbia University In The City Of New York Unique associated kaposi's sarcoma virus sequences and uses thereof
WO1998011132A1 (en) * 1996-09-10 1998-03-19 The University Of Liverpool An immunogenic determinant for use in the diagnosis of kaposi's sarcoma
EP0893504A1 (en) * 1997-07-11 1999-01-27 Biotest AG Polypeptide coded by the Kaposi sarcoma-associated virus (KSHV, HHV-8) and its uses in diagnostic and therapy

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHANG Y ET AL: "IDENTIFICATION OF HERPESVIRUS-LIKE DNA SEQUENCES IN AIDS -ASSOCIATED KAPOSI'S SARCOMA", SCIENCE, vol. 266, 16 December 1994 (1994-12-16), pages 1865 - 1869, XP000601301, ISSN: 0036-8075 *
PAU CP ET AL: "Mapping and serodiagnostic application of a dominant epitope within the human herpesvirus 8 ORF 65-encoded protein", JOURNAL OF CLINICAL MICROBIOLOGY, vol. 36, no. 6, June 1998 (1998-06-01), pages 1574 - 1577 1577, XP002103027, ISSN: 0095-1137 *
RUSSO J J ET AL: "NUCLEOTIDE SEQUENCE OF THE KAPOSI SARCOMA-ASSOCIATED HERPESVIRUS (HHV8)", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 93, no. 25, 10 December 1996 (1996-12-10), pages 14862 - 14867, XP000645332, ISSN: 0027-8424 *
SIMPSON G R ET AL: "PREVALENCE OF KAPOSI'S SARCOMA ASSOCIATED HERPESVIRUS INFECTION MEASURED BY ANTIBODIES TO RECOMBINANT CAPSID PROTEIN AND LATENT IMMUNOFLUORESCENCE ANTIGEN", LANCET THE, vol. 348, no. 9035, 26 October 1996 (1996-10-26), pages 1133 - 1138, XP002050059, ISSN: 0140-6736 *
ZHONG W ET AL: "RESTRICTED EXPRESSION OF KAPOSI SARCOMA-ASSOCIATED HERPESVIRUS (HUMAN HERPESVIRUS 8) GENES IN KAPOSI SARCOMA", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 93, 1 June 1996 (1996-06-01), pages 6641 - 6646, XP002050061, ISSN: 0027-8424 *

Also Published As

Publication number Publication date
AU4095899A (en) 1999-12-13
WO1999061909A2 (en) 1999-12-02

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