WO1999061599A3 - Recombinant narbonolide polyketide synthase - Google Patents
Recombinant narbonolide polyketide synthase Download PDFInfo
- Publication number
- WO1999061599A3 WO1999061599A3 PCT/US1999/011814 US9911814W WO9961599A3 WO 1999061599 A3 WO1999061599 A3 WO 1999061599A3 US 9911814 W US9911814 W US 9911814W WO 9961599 A3 WO9961599 A3 WO 9961599A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polyketide synthase
- narbonolide
- recombinant
- recombinant narbonolide
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/65—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression using markers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
NZ509006A NZ509006A (en) | 1998-05-28 | 1999-05-27 | Recombinant narbonolide polyketide synthase |
EP99925954A EP1082439A2 (en) | 1998-05-28 | 1999-05-27 | Recombinant narbonolide polyketide synthase |
JP2000550984A JP2002516090A (en) | 1998-05-28 | 1999-05-27 | Recombinant narvonolide polyketide synthase |
AU42137/99A AU762399C (en) | 1998-05-28 | 1999-05-27 | Recombinant narbonolide polyketide synthase |
CA002328427A CA2328427A1 (en) | 1998-05-28 | 1999-05-27 | Recombinant narbonolide polyketide synthase |
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8708098P | 1998-05-28 | 1998-05-28 | |
US60/087,080 | 1998-05-28 | ||
US09/141,908 | 1998-08-28 | ||
US09/141,908 US6503741B1 (en) | 1998-05-28 | 1998-08-28 | Polyketide synthase genes from Streptomyces venezuelae |
US10088098P | 1998-09-22 | 1998-09-22 | |
US60/100,880 | 1998-09-22 | ||
US11913999P | 1999-02-08 | 1999-02-08 | |
US60/119,139 | 1999-02-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999061599A2 WO1999061599A2 (en) | 1999-12-02 |
WO1999061599A3 true WO1999061599A3 (en) | 2000-01-27 |
Family
ID=27492096
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1999/011814 WO1999061599A2 (en) | 1998-05-28 | 1999-05-27 | Recombinant narbonolide polyketide synthase |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP1082439A2 (en) |
JP (1) | JP2002516090A (en) |
AU (1) | AU762399C (en) |
CA (1) | CA2328427A1 (en) |
NZ (1) | NZ509006A (en) |
WO (1) | WO1999061599A2 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6265202B1 (en) | 1998-06-26 | 2001-07-24 | Regents Of The University Of Minnesota | DNA encoding methymycin and pikromycin |
EP1754700A3 (en) | 1999-01-27 | 2007-05-09 | Kosan Biosciences, Inc. | Synthesis of oligoketides |
US6524841B1 (en) | 1999-10-08 | 2003-02-25 | Kosan Biosciences, Inc. | Recombinant megalomicin biosynthetic genes and uses thereof |
US7033818B2 (en) | 1999-10-08 | 2006-04-25 | Kosan Biosciences, Inc. | Recombinant polyketide synthase genes |
US6838265B2 (en) | 2000-05-02 | 2005-01-04 | Kosan Biosciences, Inc. | Overproduction hosts for biosynthesis of polyketides |
WO2002059322A2 (en) * | 2000-10-17 | 2002-08-01 | Cubist Pharmaceuticlas, Inc. | Compositions and methods relating to the daptomycin biosynthetic gene cluster |
WO2003078411A1 (en) | 2002-03-12 | 2003-09-25 | Bristol-Myers Squibb Company | C3-cyano epothilone derivatives |
DK2668284T3 (en) | 2011-01-28 | 2014-12-15 | Amyris Inc | Screening of colony micro encapsulated in gel |
MX2013013065A (en) | 2011-05-13 | 2013-12-02 | Amyris Inc | Methods and compositions for detecting microbial production of water-immiscible compounds. |
US10927382B2 (en) | 2012-08-07 | 2021-02-23 | Amyris, Inc. | Methods for stabilizing production of acetyl-coenzyme a derived compounds |
KR102159691B1 (en) | 2013-03-15 | 2020-09-24 | 아미리스 인코퍼레이티드 | Use of phosphoketolase and phosphotransacetylase for production of acetyl-coenzyme a derived compounds |
PT3030662T (en) | 2013-08-07 | 2020-03-25 | Amyris Inc | Methods for stabilizing production of acetyl-coenzyme a derived compounds |
AU2016284696B2 (en) | 2015-06-25 | 2021-10-28 | Amyris, Inc. | Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996040968A1 (en) * | 1995-06-07 | 1996-12-19 | The Leland Stanford Junior University | Recombinant production of novel polyketides |
WO1998001546A2 (en) * | 1996-07-05 | 1998-01-15 | Biotica Technology Limited | Polyketides and their synthesis |
-
1999
- 1999-05-27 AU AU42137/99A patent/AU762399C/en not_active Ceased
- 1999-05-27 CA CA002328427A patent/CA2328427A1/en not_active Abandoned
- 1999-05-27 NZ NZ509006A patent/NZ509006A/en unknown
- 1999-05-27 WO PCT/US1999/011814 patent/WO1999061599A2/en not_active Application Discontinuation
- 1999-05-27 EP EP99925954A patent/EP1082439A2/en not_active Withdrawn
- 1999-05-27 JP JP2000550984A patent/JP2002516090A/en not_active Withdrawn
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996040968A1 (en) * | 1995-06-07 | 1996-12-19 | The Leland Stanford Junior University | Recombinant production of novel polyketides |
WO1998001546A2 (en) * | 1996-07-05 | 1998-01-15 | Biotica Technology Limited | Polyketides and their synthesis |
Non-Patent Citations (1)
Title |
---|
BROWN M J B ET AL: "A MUTANT GENERATED BY EXPRESSION OF AN ENGINEERED DEBS1 PROTEIN FROM THE ERYTHROMYCIN-PRODUCING POLYKETIDE SYNTHASE (PKS) IN STREPTOMYCES COELICOLOR PRODUCES THE TRIKETIDE AS A LACTONE, BUT THE MAJOR PRODUCT IS THE NOR-ANALOGUE DERIVED FROM ACETATE AS STARTER ACID", JOURNAL OF THE CHEMICAL SOCIETY, CHEMICAL COMMUNICATIONS,GB,CHEMICAL SOCIETY. LETCHWORTH, no. 15, 1995, pages 1517-1518, XP002044729, ISSN: 0022-4936 * |
Also Published As
Publication number | Publication date |
---|---|
AU762399B2 (en) | 2003-06-26 |
AU762399C (en) | 2004-02-05 |
NZ509006A (en) | 2003-09-26 |
EP1082439A2 (en) | 2001-03-14 |
JP2002516090A (en) | 2002-06-04 |
CA2328427A1 (en) | 1999-12-02 |
AU4213799A (en) | 1999-12-13 |
WO1999061599A2 (en) | 1999-12-02 |
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