WO1999061067A8 - Gene expression method - Google Patents

Gene expression method

Info

Publication number
WO1999061067A8
WO1999061067A8 PCT/US1999/011697 US9911697W WO9961067A8 WO 1999061067 A8 WO1999061067 A8 WO 1999061067A8 US 9911697 W US9911697 W US 9911697W WO 9961067 A8 WO9961067 A8 WO 9961067A8
Authority
WO
WIPO (PCT)
Prior art keywords
factor
expression
gene expression
transgene
nucleic acid
Prior art date
Application number
PCT/US1999/011697
Other languages
French (fr)
Other versions
WO1999061067B1 (en
WO1999061067A1 (en
Inventor
Joseph C Glorioso
Darren P Wolfe
William F Goins
Original Assignee
Univ Pittsburgh
Joseph C Glorioso
Darren P Wolfe
William F Goins
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Pittsburgh, Joseph C Glorioso, Darren P Wolfe, William F Goins filed Critical Univ Pittsburgh
Priority to AU42103/99A priority Critical patent/AU4210399A/en
Priority to EP99925911A priority patent/EP1082140A1/en
Publication of WO1999061067A1 publication Critical patent/WO1999061067A1/en
Publication of WO1999061067B1 publication Critical patent/WO1999061067B1/en
Publication of WO1999061067A8 publication Critical patent/WO1999061067A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Abstract

The present invention provides a method of delivering a factor to non-neural tissue and a method of treating neuropathy. The method involves introducing an expression cassette including a nucleic acid for expression involved in the production of the factor into a neural cell, within which the nucleic acid for expression is expressed, and from which the factor is therefore secreted. The method also provides a method of promoting long-term gene expression in vivo, by employing a herpesvirus to deliver a transgene to a desired tissue of a host animal. The method also permits repeat administration of the transgene.
PCT/US1999/011697 1998-05-27 1999-05-27 Gene expression method WO1999061067A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU42103/99A AU4210399A (en) 1998-05-27 1999-05-27 Gene expression method
EP99925911A EP1082140A1 (en) 1998-05-27 1999-05-27 Gene expression method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8693598P 1998-05-27 1998-05-27
US60/086,935 1998-05-27

Publications (3)

Publication Number Publication Date
WO1999061067A1 WO1999061067A1 (en) 1999-12-02
WO1999061067B1 WO1999061067B1 (en) 2000-02-10
WO1999061067A8 true WO1999061067A8 (en) 2001-03-15

Family

ID=22201850

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/011697 WO1999061067A1 (en) 1998-05-27 1999-05-27 Gene expression method

Country Status (3)

Country Link
EP (1) EP1082140A1 (en)
AU (1) AU4210399A (en)
WO (1) WO1999061067A1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9580699B2 (en) 2014-04-17 2017-02-28 University of Pittsburgh—of the Commonwealth System of Higher Education TRPV1 modulatory gene product that affects TRPV1-specific pain behavioral responses identified in a functional screen of an HSV-based cDNA library

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849571A (en) * 1990-10-10 1998-12-15 University Of Pittsburgh Of The Commonwealth System Of Higher Education Latency active herpes virus promoters and their use

Also Published As

Publication number Publication date
WO1999061067B1 (en) 2000-02-10
EP1082140A1 (en) 2001-03-14
WO1999061067A1 (en) 1999-12-02
AU4210399A (en) 1999-12-13

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