WO1999056727A3 - Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems - Google Patents
Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems Download PDFInfo
- Publication number
- WO1999056727A3 WO1999056727A3 PCT/IE1999/000031 IE9900031W WO9956727A3 WO 1999056727 A3 WO1999056727 A3 WO 1999056727A3 IE 9900031 W IE9900031 W IE 9900031W WO 9956727 A3 WO9956727 A3 WO 9956727A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- preconcentrate
- solvent
- emulsion
- drug delivery
- delivery systems
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4858—Organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2000546754A JP2002513750A (en) | 1998-05-07 | 1999-05-07 | Solvent / co-solvent free microemulsion and emulsion pre-concentrate drug delivery system |
EP99921098A EP1075252A2 (en) | 1998-05-07 | 1999-05-07 | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
AU38439/99A AU3843999A (en) | 1998-05-07 | 1999-05-07 | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
CA002331640A CA2331640A1 (en) | 1998-05-07 | 1999-05-07 | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US8451898P | 1998-05-07 | 1998-05-07 | |
US60/084,518 | 1998-05-07 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999056727A2 WO1999056727A2 (en) | 1999-11-11 |
WO1999056727A3 true WO1999056727A3 (en) | 2000-03-02 |
Family
ID=22185451
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IE1999/000031 WO1999056727A2 (en) | 1998-05-07 | 1999-05-07 | Solvent/cosolvent free microemulsion and emulsion preconcentrate drug delivery systems |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1075252A2 (en) |
JP (1) | JP2002513750A (en) |
AU (1) | AU3843999A (en) |
CA (1) | CA2331640A1 (en) |
WO (1) | WO1999056727A2 (en) |
Cited By (4)
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US7709669B2 (en) | 2000-02-16 | 2010-05-04 | The Brigham And Women's Hospital, Inc. | Aspirin-triggered lipid mediators |
US7741368B2 (en) | 2001-12-18 | 2010-06-22 | The Brigham And Women's Hospital, Inc. | Approach to antimicrobial host defense with molecular shields with EPA and DHA analogs |
US7759395B2 (en) | 2002-08-12 | 2010-07-20 | The Brigham And Women's Hospital, Inc. | Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma |
US9364454B2 (en) | 2005-10-03 | 2016-06-14 | The Brigham And Women's Hospital, Inc. | Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers |
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US6294192B1 (en) | 1999-02-26 | 2001-09-25 | Lipocine, Inc. | Triglyceride-free compositions and methods for improved delivery of hydrophobic therapeutic agents |
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US7582785B2 (en) | 2002-04-01 | 2009-09-01 | University Of Southern California | Trihydroxy polyunsaturated eicosanoid derivatives |
CA2493878C (en) | 2002-07-30 | 2013-07-23 | Wyeth | Parenteral formulations containing a rapamycin hydroxyester |
EP1537067B1 (en) | 2002-08-12 | 2009-11-18 | Brigham And Women's Hospital | Resolvins: biotemplates for therapeutic interventions |
US20040146551A1 (en) | 2002-11-01 | 2004-07-29 | Biodelivery Sciences International, Inc. | Geodate delivery vehicles |
US7842791B2 (en) | 2002-12-19 | 2010-11-30 | Nancy Jean Britten | Dispersible pharmaceutical compositions |
US20040185068A1 (en) * | 2003-03-18 | 2004-09-23 | Zhi-Jian Yu | Self-emulsifying compositions, methods of use and preparation |
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US7879345B2 (en) | 2003-04-11 | 2011-02-01 | L'oreal | Composition containing an amphiphilic polymer, uses thereof |
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ES2425937T3 (en) * | 2004-03-24 | 2013-10-18 | Takeda Pharmaceutical Company Limited | Emulsion stabilizer |
US20050232974A1 (en) * | 2004-04-19 | 2005-10-20 | Gore Makarand P | System and a method for pharmaceutical dosage preparation using jettable microemulsions |
SG155189A1 (en) * | 2004-08-06 | 2009-09-30 | Transform Pharmaceuticals Inc | Novel fenofibrate formulations and related methods of treatment |
CN100361656C (en) | 2004-08-27 | 2008-01-16 | 石药集团中奇制药技术(石家庄)有限公司 | Butylbenzene phthalein self emulsifying releasing medicine system, preparation method and application |
GT200500310A (en) | 2004-11-19 | 2006-06-19 | ORGANIC COMPOUNDS | |
WO2008051186A2 (en) * | 2005-08-09 | 2008-05-02 | Nanobio Corporation | Nanoemulsion containing compositions having ant i -inflammatory activity |
US20140287004A1 (en) * | 2005-11-14 | 2014-09-25 | The Trustees Of Columbia University In The City Of New York | Use of an Omega-3 Lipid-Based Emulsion Following Ischemic Injury to Provide Protection and Recovery in Human Organs |
WO2014160989A2 (en) | 2013-03-28 | 2014-10-02 | The Trustees Of Columbia University In The City Of New York | Reperfusion with omega-3 glycerides promotes donor organ protection for transplantation |
WO2007059431A1 (en) * | 2005-11-14 | 2007-05-24 | The Trustees Of Columbia University In The City Of New York | Use of an omega-3 lipid-based emulsion following ischemic injury to provide protection and recovery in human organs |
EP1957053A4 (en) * | 2005-11-17 | 2012-03-28 | Bioavailability Inc | Biocompatible latent emulsifiers |
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US20090130198A1 (en) * | 2007-11-21 | 2009-05-21 | Innopharmax Inc. | Pharmaceutical composition with enhanced bioavailability |
FR2925855B1 (en) | 2007-12-26 | 2010-11-05 | Virbac Sa | FLORFENICOL SELF-CONTAINING LIQUID COMPOSITION FOR INCORPORATING BEVERAGE WATER IN ANIMAL BREEDING ANIMALS. |
EP2405902B1 (en) | 2009-03-09 | 2021-07-21 | Basf As | Compositions comprising a fatty acid oil mixture and a surfactant, and methods and uses thereof |
EP2433630A4 (en) * | 2009-05-22 | 2014-01-08 | Mochida Pharm Co Ltd | Self-emulsifying composition of 3 fatty acid |
JP2011006380A (en) * | 2009-05-22 | 2011-01-13 | Mochida Pharmaceut Co Ltd | EMULSIFIED COMPOSITION OF ω3 FATTY ACID |
US9717703B2 (en) | 2009-10-16 | 2017-08-01 | Glaxosmithkline Llc | Emulsion and emulsion preconcentrate compositions comprising omega-3 fatty acids and uses thereof are disclosed |
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EP2366408B1 (en) | 2010-03-01 | 2012-07-18 | Laboratorios SALVAT, S.A. | Aqueous clear solutions of fluocinolone acetonide for treatment of otic inflammation |
KR101752944B1 (en) | 2010-05-03 | 2017-07-03 | 테이코쿠 팔마 유에스에이, 인코포레이티드 | Non-aqueous taxane pro-emulsion formulations and methods of making and using the same |
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US11400048B2 (en) | 2014-06-25 | 2022-08-02 | Synergia Bio Sciences Private Limited | Pharmaceutical oil-in-water nano-emulsion |
US10736842B2 (en) | 2014-06-25 | 2020-08-11 | Synergia Bio Sciences Private Limited | Pharmaceutical oil-in-water nano-emulsion |
US11260018B2 (en) | 2015-09-17 | 2022-03-01 | Jrx Biotechnology, Inc. | Approaches for improving skin hydration and moisturization |
US20230158018A1 (en) * | 2018-09-13 | 2023-05-25 | Ftf Pharma Private Limited | Non-aqueous chemotherapeutic suspensions for oral dosage |
US20200215027A1 (en) * | 2018-12-28 | 2020-07-09 | Robert K. Prud'homme | Dihydromyricetin nanoemulsion formulations and methods for forming them |
US11465107B2 (en) * | 2019-01-31 | 2022-10-11 | Hong Ngoc Thi Dang | Process for producing a nano omega-3 microemulsion system |
CZ309587B6 (en) * | 2021-01-22 | 2023-05-03 | Oncora S.R.O. | Microemulsion preconcentrate containing cladribine and preparing it |
Citations (13)
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---|---|---|---|---|
FR2372635A1 (en) * | 1976-12-03 | 1978-06-30 | Scherer Ltd R P | Pharmaceutical compsn. contg. self-emulsifying oil e.g. silicone - for admin. as capsules, giving rapid gastrointestinal resorption |
WO1994005298A1 (en) * | 1992-08-28 | 1994-03-17 | Pharmos Corporation | Submicron emulsions as ocular drug delivery vehicles |
WO1995008983A1 (en) * | 1993-09-30 | 1995-04-06 | Gattefosse S.A. | Oral delivery composition forming a microemulsion |
EP0650721A1 (en) * | 1993-07-01 | 1995-05-03 | Hanmi Pharm. Ind. Co., Ltd. | Cyclosporin soft capsule |
WO1995012384A1 (en) * | 1993-11-02 | 1995-05-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Self-emulsible formulation forming an oil-in-water emulsion |
WO1995025504A1 (en) * | 1994-03-18 | 1995-09-28 | Pharmavene, Inc. | Emulsified drug delivery systems |
WO1996013273A1 (en) * | 1994-10-26 | 1996-05-09 | Novartis Ag | Pharmaceutical compositions |
EP0760237A1 (en) * | 1995-08-30 | 1997-03-05 | Cipla Limited | Oil-in-water microemulsions |
US5639724A (en) * | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
WO1997036610A1 (en) * | 1996-07-26 | 1997-10-09 | Chong Kun Dang Corp. | Cyclosporin-containing pharmaceutical composition |
FR2753376A1 (en) * | 1996-09-18 | 1998-03-20 | Synthelabo | PHARMACEUTICAL COMPOSITIONS COMPRISING AMISULPRIDE AND THERAPEUTIC APPLICATIONS THEREOF |
WO1999029316A1 (en) * | 1997-12-10 | 1999-06-17 | Severson, Mary, L. | Pharmaceutical compositions containing an omega-3 fatty acid oil |
WO1999029300A1 (en) * | 1997-12-10 | 1999-06-17 | Rtp Pharma Inc. | Self-emulsifying fenofibrate formulations |
-
1999
- 1999-05-07 JP JP2000546754A patent/JP2002513750A/en active Pending
- 1999-05-07 WO PCT/IE1999/000031 patent/WO1999056727A2/en not_active Application Discontinuation
- 1999-05-07 AU AU38439/99A patent/AU3843999A/en not_active Abandoned
- 1999-05-07 CA CA002331640A patent/CA2331640A1/en not_active Abandoned
- 1999-05-07 EP EP99921098A patent/EP1075252A2/en not_active Withdrawn
Patent Citations (13)
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FR2372635A1 (en) * | 1976-12-03 | 1978-06-30 | Scherer Ltd R P | Pharmaceutical compsn. contg. self-emulsifying oil e.g. silicone - for admin. as capsules, giving rapid gastrointestinal resorption |
US5639724A (en) * | 1984-07-24 | 1997-06-17 | Sandoz Ltd. | Cyclosporin galenic forms |
WO1994005298A1 (en) * | 1992-08-28 | 1994-03-17 | Pharmos Corporation | Submicron emulsions as ocular drug delivery vehicles |
EP0650721A1 (en) * | 1993-07-01 | 1995-05-03 | Hanmi Pharm. Ind. Co., Ltd. | Cyclosporin soft capsule |
WO1995008983A1 (en) * | 1993-09-30 | 1995-04-06 | Gattefosse S.A. | Oral delivery composition forming a microemulsion |
WO1995012384A1 (en) * | 1993-11-02 | 1995-05-11 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Self-emulsible formulation forming an oil-in-water emulsion |
WO1995025504A1 (en) * | 1994-03-18 | 1995-09-28 | Pharmavene, Inc. | Emulsified drug delivery systems |
WO1996013273A1 (en) * | 1994-10-26 | 1996-05-09 | Novartis Ag | Pharmaceutical compositions |
EP0760237A1 (en) * | 1995-08-30 | 1997-03-05 | Cipla Limited | Oil-in-water microemulsions |
WO1997036610A1 (en) * | 1996-07-26 | 1997-10-09 | Chong Kun Dang Corp. | Cyclosporin-containing pharmaceutical composition |
FR2753376A1 (en) * | 1996-09-18 | 1998-03-20 | Synthelabo | PHARMACEUTICAL COMPOSITIONS COMPRISING AMISULPRIDE AND THERAPEUTIC APPLICATIONS THEREOF |
WO1999029316A1 (en) * | 1997-12-10 | 1999-06-17 | Severson, Mary, L. | Pharmaceutical compositions containing an omega-3 fatty acid oil |
WO1999029300A1 (en) * | 1997-12-10 | 1999-06-17 | Rtp Pharma Inc. | Self-emulsifying fenofibrate formulations |
Non-Patent Citations (2)
Title |
---|
CRAIG D Q M ET AL: "A COMPARISON OF THE SELF-EMULSIFYING PROPERTIES OF POLYGLYCOLYSED GLYCERIDE OILS", PHARMACEUTICAL SCIENCES,GB,LONDON, vol. 1, no. 12, pages 559-561, XP002053051, ISSN: 1356-6881 * |
SHAH N H ET AL: "SELF-EMULSIFYING DRUG DELIVERY SYSTEMS (SEDDS) WITH POLYGLYCOLYZED GLYCERIDES FOR IMPROVING IN VITRO DISSOLUTION AND ORAL ABSORPTION OF LIPOPHILIC DRUGS", INTERNATIONAL JOURNAL OF PHARMACEUTICS,NL,AMSTERDAM, vol. 106, no. 1, pages 15-23, XP000561369, ISSN: 0378-5173 * |
Cited By (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7709669B2 (en) | 2000-02-16 | 2010-05-04 | The Brigham And Women's Hospital, Inc. | Aspirin-triggered lipid mediators |
US7741368B2 (en) | 2001-12-18 | 2010-06-22 | The Brigham And Women's Hospital, Inc. | Approach to antimicrobial host defense with molecular shields with EPA and DHA analogs |
US7759395B2 (en) | 2002-08-12 | 2010-07-20 | The Brigham And Women's Hospital, Inc. | Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma |
US7872152B2 (en) | 2002-08-12 | 2011-01-18 | The Brigham And Women's Hospital, Inc. | Use of docosatrienes, resolvins and their stable analogs in the treatment of airway diseases and asthma |
US8933270B2 (en) | 2002-08-12 | 2015-01-13 | The Brigham And Women's Hospital, Inc. | Use of docasatrienes, resolvins, and their stable analogs in the treatment of airway diseases and asthma |
US9364454B2 (en) | 2005-10-03 | 2016-06-14 | The Brigham And Women's Hospital, Inc. | Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers |
Also Published As
Publication number | Publication date |
---|---|
WO1999056727A2 (en) | 1999-11-11 |
JP2002513750A (en) | 2002-05-14 |
CA2331640A1 (en) | 1999-11-11 |
AU3843999A (en) | 1999-11-23 |
EP1075252A2 (en) | 2001-02-14 |
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