WO1999054707A3 - Fetal testing for prediction of low birth weight - Google Patents

Fetal testing for prediction of low birth weight Download PDF

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Publication number
WO1999054707A3
WO1999054707A3 PCT/US1999/008794 US9908794W WO9954707A3 WO 1999054707 A3 WO1999054707 A3 WO 1999054707A3 US 9908794 W US9908794 W US 9908794W WO 9954707 A3 WO9954707 A3 WO 9954707A3
Authority
WO
WIPO (PCT)
Prior art keywords
birth weight
prediction
low birth
fetal testing
fetal
Prior art date
Application number
PCT/US1999/008794
Other languages
French (fr)
Other versions
WO1999054707A2 (en
Inventor
Kenneth S Kornman
Steven Offenbacher
Gordon W Duff
Original Assignee
Interleukin Genetics Inc
Kenneth S Kornman
Steven Offenbacher
Gordon W Duff
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Interleukin Genetics Inc, Kenneth S Kornman, Steven Offenbacher, Gordon W Duff filed Critical Interleukin Genetics Inc
Priority to CA002328955A priority Critical patent/CA2328955C/en
Priority to IL13913199A priority patent/IL139131A0/en
Priority to JP2000545003A priority patent/JP2002512047A/en
Priority to EP99919959A priority patent/EP1071822A2/en
Priority to AU37557/99A priority patent/AU769949B2/en
Publication of WO1999054707A2 publication Critical patent/WO1999054707A2/en
Publication of WO1999054707A3 publication Critical patent/WO1999054707A3/en
Priority to US09/693,555 priority patent/US6733967B1/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/172—Haplotypes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Reproductive Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

Methods, assays and kits are disclosed for detecting a mother's or a fetus's susceptibility to an adverse pregnancy outcome such as low birth weight. The methods comprise obtaining a biological sample from a patient and determining the presence or absence of an IL-1 allele 2 of a marker that is associated with an adverse pregnancy outcome.
PCT/US1999/008794 1998-04-21 1999-04-21 Fetal testing for prediction of low birth weight WO1999054707A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
CA002328955A CA2328955C (en) 1998-04-21 1999-04-21 Fetal testing for prediction of low birth weight
IL13913199A IL139131A0 (en) 1998-04-21 1999-04-21 Fetal testing for prediction of low birth weight
JP2000545003A JP2002512047A (en) 1998-04-21 1999-04-21 Fetal testing to predict low birth weight
EP99919959A EP1071822A2 (en) 1998-04-21 1999-04-21 Fetal testing for prediction of low birth weight
AU37557/99A AU769949B2 (en) 1998-04-21 1999-04-21 Fetal testing for prediction of low birth weight
US09/693,555 US6733967B1 (en) 1998-04-21 2000-10-20 Fetal testing for prediction of low birth weight

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8248798P 1998-04-21 1998-04-21
US60/082,487 1998-04-21

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09/693,555 Continuation-In-Part US6733967B1 (en) 1998-04-21 2000-10-20 Fetal testing for prediction of low birth weight

Publications (2)

Publication Number Publication Date
WO1999054707A2 WO1999054707A2 (en) 1999-10-28
WO1999054707A3 true WO1999054707A3 (en) 2000-06-22

Family

ID=22171538

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/008794 WO1999054707A2 (en) 1998-04-21 1999-04-21 Fetal testing for prediction of low birth weight

Country Status (6)

Country Link
EP (1) EP1071822A2 (en)
JP (1) JP2002512047A (en)
AU (1) AU769949B2 (en)
CA (1) CA2328955C (en)
IL (1) IL139131A0 (en)
WO (1) WO1999054707A2 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6524795B1 (en) * 1997-03-10 2003-02-25 Interleukin Genetics, Inc. Diagnostics for cardiovascular disorders
WO2002000933A2 (en) * 2000-06-23 2002-01-03 Interleukin Genetics, Inc. Screening assays for identifying modulators of the inflammatory or immune responses
WO2002022877A2 (en) * 2000-09-12 2002-03-21 The Brigham And Women's Hospital, Inc. Variants of il-1 beta gene and cd46 gene for diagnosing unexplained recurrent pregnancy loss
AU2001263373A1 (en) * 2000-09-20 2002-04-02 Genaissance Pharmaceuticals, Inc. Haplotypes of the il1b gene
CN102802442B (en) 2009-06-16 2014-05-07 株式会社明治 Prenatal milk-derived composition for preventing the risk of low birthweight of newborns
CN103981279B (en) * 2014-06-09 2015-10-28 东莞市石龙博爱医院 Low birthweight infant genovariation detection primer and detection kit, detection method and application

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997006180A1 (en) * 1995-08-03 1997-02-20 Medical Science Systems, Inc. Detecting genetic predisposition to periodontal disease
WO1997038135A1 (en) * 1996-04-05 1997-10-16 Medical Science Systems, Inc. Detecting genetic predisposition for osteoporosis
WO1998015653A1 (en) * 1996-10-10 1998-04-16 Gordon Duff Detecting genetic predisposition to sight-threatening diabetic retinopathy
WO1998040517A1 (en) * 1997-03-10 1998-09-17 Medical Science Systems, Inc. Prediction of coronary artery disease
WO1998054359A1 (en) * 1997-05-29 1998-12-03 Gordon Duff Prediction of inflammatory disease associated with il-1 geneloci polymorphisms

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997006180A1 (en) * 1995-08-03 1997-02-20 Medical Science Systems, Inc. Detecting genetic predisposition to periodontal disease
WO1997038135A1 (en) * 1996-04-05 1997-10-16 Medical Science Systems, Inc. Detecting genetic predisposition for osteoporosis
WO1998015653A1 (en) * 1996-10-10 1998-04-16 Gordon Duff Detecting genetic predisposition to sight-threatening diabetic retinopathy
WO1998040517A1 (en) * 1997-03-10 1998-09-17 Medical Science Systems, Inc. Prediction of coronary artery disease
WO1998054359A1 (en) * 1997-05-29 1998-12-03 Gordon Duff Prediction of inflammatory disease associated with il-1 geneloci polymorphisms

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
J. Periodontol., 67, october 1996, 1103 Offenbacher S. et al., Periodontal infection as a possible risk factor for preterm low birth weight *

Also Published As

Publication number Publication date
IL139131A0 (en) 2001-11-25
CA2328955A1 (en) 1999-10-28
WO1999054707A2 (en) 1999-10-28
EP1071822A2 (en) 2001-01-31
AU3755799A (en) 1999-11-08
AU769949B2 (en) 2004-02-12
CA2328955C (en) 2008-03-18
JP2002512047A (en) 2002-04-23

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