WO1999054466A3 - Antigenes associes au cancer du colon, et utilisations desdits antigenes a des fins diagnostiques ou therapeutiques - Google Patents

Antigenes associes au cancer du colon, et utilisations desdits antigenes a des fins diagnostiques ou therapeutiques Download PDF

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Publication number
WO1999054466A3
WO1999054466A3 PCT/US1999/008672 US9908672W WO9954466A3 WO 1999054466 A3 WO1999054466 A3 WO 1999054466A3 US 9908672 W US9908672 W US 9908672W WO 9954466 A3 WO9954466 A3 WO 9954466A3
Authority
WO
WIPO (PCT)
Prior art keywords
diagnostic
colon cancer
associated antigens
therapeutic uses
cancer
Prior art date
Application number
PCT/US1999/008672
Other languages
English (en)
Other versions
WO1999054466A2 (fr
Inventor
Fei Huang
Paul B Fisher
Neil I Goldstein
Original Assignee
Fei Huang
Paul B Fisher
Neil I Goldstein
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fei Huang, Paul B Fisher, Neil I Goldstein filed Critical Fei Huang
Priority to AU37534/99A priority Critical patent/AU3753499A/en
Publication of WO1999054466A2 publication Critical patent/WO1999054466A2/fr
Publication of WO1999054466A3 publication Critical patent/WO1999054466A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5156—Animal cells expressing foreign proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

L'invention concerne des compositions et des méthodes de dépistage du cancer et de thérapie anticancéreuse. Ces composés comportent des protéines associées aux tumeurs, des parties de celles-ci et leurs variants, ainsi que des polynucléotides codant de tels polypeptides. L'invention concerne également des vaccins et des compositions pharmaceutiques qui comprennent ces composés et qui peuvent être utilisés, par exemple, pour la prévention et le traitement du cancer. Ces polypeptides peuvent également être utilisés pour la production d'anticorps utiles pour diagnostiquer et surveiller l'évolution du cancer chez un patient.
PCT/US1999/008672 1998-04-20 1999-04-20 Antigenes associes au cancer du colon, et utilisations desdits antigenes a des fins diagnostiques ou therapeutiques WO1999054466A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU37534/99A AU3753499A (en) 1998-04-20 1999-04-20 Colon cancer-associated antigens and their diagnostic and therapeutic uses

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8244198P 1998-04-20 1998-04-20
US60/082,441 1998-04-20

Publications (2)

Publication Number Publication Date
WO1999054466A2 WO1999054466A2 (fr) 1999-10-28
WO1999054466A3 true WO1999054466A3 (fr) 2000-02-17

Family

ID=22171243

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/008672 WO1999054466A2 (fr) 1998-04-20 1999-04-20 Antigenes associes au cancer du colon, et utilisations desdits antigenes a des fins diagnostiques ou therapeutiques

Country Status (2)

Country Link
AU (1) AU3753499A (fr)
WO (1) WO1999054466A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU6531101A (en) * 2000-06-02 2001-12-17 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
EP1354040A2 (fr) * 2000-07-20 2003-10-22 Genentech, Inc. Polypeptides secretes et transmembranaires et acides nucleiques codant ces polypeptides
EP2591786B1 (fr) * 2003-10-16 2017-04-12 Cancure Limited Compositions immunomodulatrices et leurs utilisations

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995003422A1 (fr) * 1993-07-22 1995-02-02 Ludwig Institute For Cancer Research Methode de diagnostic d'une anomalie par mise en evidence de l'expression des precurseurs gage des antigenes de rejet des tumeurs
DE19547529A1 (de) * 1995-12-10 1997-06-12 Reutter Werner Prof Dr Med Hybridomzellklone, die monoklonale Antikörper synthetisieren mit hoher Selektivität und Spezifität für Dickdarmkarzinomzellen mit einem Antigen vom Molekulargewicht 70k; ihre Anwendung in Diagnostik und Therapie

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995003422A1 (fr) * 1993-07-22 1995-02-02 Ludwig Institute For Cancer Research Methode de diagnostic d'une anomalie par mise en evidence de l'expression des precurseurs gage des antigenes de rejet des tumeurs
DE19547529A1 (de) * 1995-12-10 1997-06-12 Reutter Werner Prof Dr Med Hybridomzellklone, die monoklonale Antikörper synthetisieren mit hoher Selektivität und Spezifität für Dickdarmkarzinomzellen mit einem Antigen vom Molekulargewicht 70k; ihre Anwendung in Diagnostik und Therapie

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL - EMEST18 13 June 1997 (1997-06-13), MARRA, M. ET AL.: "vf89e05.r1 Soares mouse mammary gland NbMMG Mus musculus cDNA clone 850976 5'.", XP002111975 *
DATABASE EMBL - R57U053 9 February 1999 (1999-02-09), NAGASE, T. ET AL.: "Homo sapiens mRNA for KIAA0826 protein, partial cds.", XP002111976 *
GRIMM T ET AL: "A modified screening method for pcDNA-1 expression libraries which is applicable to both surface and intracellular antigens Cloning of a colon carcinoma antigen", JOURNAL OF IMMUNOLOGICAL METHODS, vol. 186, no. 2, 16 October 1995 (1995-10-16), pages 305-312, XP004021231, ISSN: 0022-1759 *
NAGASE, T. ET AL.: "Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.", DNA RESEARCH, vol. 5, December 1998 (1998-12-01), pages 355 - 64, XP002111974 *
VAN BELZEN N ET AL: "Detection of different gene expression in differentiating colon carcinoma cells by differential display", JOURNAL OF PATHOLOGY, vol. 178, 1 January 1996 (1996-01-01), pages 2A, XP002089886, ISSN: 0022-3417 *
VEILLETTE A ET AL: "EXPRESSION OF THE LCK TYROSINE KINASE GENE IN HUMAN COLON CARCINOMA AND OTHER NON-LYMPHOID HUMAN TUMOR CELL LINES", ONCOGENE RESEARCH, vol. 1, 1987, pages 357 - 374, XP002912135 *

Also Published As

Publication number Publication date
AU3753499A (en) 1999-11-08
WO1999054466A2 (fr) 1999-10-28

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