WO1999052587A3 - Methods and systems for the mass production of radioactive materials - Google Patents

Methods and systems for the mass production of radioactive materials Download PDF

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Publication number
WO1999052587A3
WO1999052587A3 PCT/US1999/007663 US9907663W WO9952587A3 WO 1999052587 A3 WO1999052587 A3 WO 1999052587A3 US 9907663 W US9907663 W US 9907663W WO 9952587 A3 WO9952587 A3 WO 9952587A3
Authority
WO
WIPO (PCT)
Prior art keywords
targets
electron beam
systems
path
radioactive materials
Prior art date
Application number
PCT/US1999/007663
Other languages
French (fr)
Other versions
WO1999052587A2 (en
Inventor
Kenneth J Weeks
Original Assignee
Univ Duke
Kenneth J Weeks
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Duke, Kenneth J Weeks filed Critical Univ Duke
Priority to AU41807/99A priority Critical patent/AU4180799A/en
Priority to JP2000543195A priority patent/JP2002511566A/en
Priority to EP99925549A priority patent/EP1087814A2/en
Priority to CA002327824A priority patent/CA2327824A1/en
Publication of WO1999052587A2 publication Critical patent/WO1999052587A2/en
Publication of WO1999052587A3 publication Critical patent/WO1999052587A3/en

Links

Classifications

    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
    • G21G1/12—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by electromagnetic irradiation, e.g. with gamma or X-rays
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
    • G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
    • G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
    • G21G1/10—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by bombardment with electrically charged particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Radiation-Therapy Devices (AREA)

Abstract

Systems and methods mass produce radioactive materials and structures, such as stents. A three-dimensional array of targets (16) is disposed in a beam path of an electron beam emitted from a source thereof (e.g., a linear accelerator (12)). A bremsstrahlung converter (14) is interposed between the array of targets and the source of the electron beam so as to convert the electron beam to an irradiating beam which contains both electrons and photons. The electrons in the irradiating beam may be divergently directed away from the beam path (e.g., by magnetic sweepers (26)) and along a divergent path so that the targets are irradiated predominantly by photons. Furthermore, the electron beam can be conditioned (focussed) by means of magnetic stirring coils (34) positioned upstream of the converter. The bremsstrahlung converter (14) is most preferably provided by a plurality of individual converters which differ from one another in terms of their thickness and/or high Z material. One or more of these individual converters (14) may thus be interposed in the beam path as may be desired in dependence upon the targets (16) to be irradiated.
PCT/US1999/007663 1998-04-10 1999-04-08 Methods and systems for the mass production of radioactive materials WO1999052587A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU41807/99A AU4180799A (en) 1998-04-10 1999-04-08 Methods and systems for the mass production of radioactive materials
JP2000543195A JP2002511566A (en) 1998-04-10 1999-04-08 Method and apparatus for mass production of radioactive materials
EP99925549A EP1087814A2 (en) 1998-04-10 1999-04-08 Methods and systems for the mass production of radioactive materials
CA002327824A CA2327824A1 (en) 1998-04-10 1999-04-08 Methods and systems for the mass production of radioactive materials

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8143598P 1998-04-10 1998-04-10
US60/081,435 1998-04-10

Publications (2)

Publication Number Publication Date
WO1999052587A2 WO1999052587A2 (en) 1999-10-21
WO1999052587A3 true WO1999052587A3 (en) 2001-02-01

Family

ID=22164150

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/007663 WO1999052587A2 (en) 1998-04-10 1999-04-08 Methods and systems for the mass production of radioactive materials

Country Status (5)

Country Link
EP (1) EP1087814A2 (en)
JP (1) JP2002511566A (en)
AU (1) AU4180799A (en)
CA (1) CA2327824A1 (en)
WO (1) WO1999052587A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2713972A1 (en) * 2010-07-27 2012-01-27 Mevex Corporation Power concentrator for electron and/or x-ray beams
US10535441B1 (en) 2010-07-27 2020-01-14 Mevex Corporation Method of irradiating a target
CA2816453C (en) * 2013-05-23 2019-09-17 Canadian Light Source Inc. Production of molybdenum-99 using electron beams
EP4191613A1 (en) * 2021-12-06 2023-06-07 Universität Bern High power converter target assembly, related facility and method to produce bremsstrahlung for photonuclear reactions
EP4243036A1 (en) 2022-03-10 2023-09-13 Ion Beam Applications System for production of radioisotopes by bremsstrahlung comprising a curved converter

Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2902613A (en) * 1954-04-09 1959-09-01 Gen Electric Adaptation of a high energy electron accelerator as a neutron source
US2929933A (en) * 1956-05-24 1960-03-22 Jr Benjamin W Ela Target assembly
US2952775A (en) * 1959-02-17 1960-09-13 Shell Oil Co Method and apparatus for the analytical determination of deuterium
US3358239A (en) * 1965-07-27 1967-12-12 Transformatoren & Roentgenwerk Equipment for controlling and monitoring the electron beam of a horizontaltype particle accelerator
US3431502A (en) * 1968-04-10 1969-03-04 Atomic Energy Commission Target positioner for accelerator external beam
US3526575A (en) * 1967-08-02 1970-09-01 Willard H Bennett Production and utilization of high density plasma
US3639849A (en) * 1966-11-28 1972-02-01 Willard H Bennett Apparatus for producing a highly concentrated beam of electrons
US4428902A (en) * 1981-05-13 1984-01-31 Murray Kenneth M Coal analysis system
US4756866A (en) * 1985-10-09 1988-07-12 Alvarez Luis W Nitrogen detection
US5342283A (en) * 1990-08-13 1994-08-30 Good Roger R Endocurietherapy
US5784423A (en) * 1995-09-08 1998-07-21 Massachusetts Institute Of Technology Method of producing molybdenum-99

Patent Citations (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2902613A (en) * 1954-04-09 1959-09-01 Gen Electric Adaptation of a high energy electron accelerator as a neutron source
US2929933A (en) * 1956-05-24 1960-03-22 Jr Benjamin W Ela Target assembly
US2952775A (en) * 1959-02-17 1960-09-13 Shell Oil Co Method and apparatus for the analytical determination of deuterium
US3358239A (en) * 1965-07-27 1967-12-12 Transformatoren & Roentgenwerk Equipment for controlling and monitoring the electron beam of a horizontaltype particle accelerator
US3639849A (en) * 1966-11-28 1972-02-01 Willard H Bennett Apparatus for producing a highly concentrated beam of electrons
US3526575A (en) * 1967-08-02 1970-09-01 Willard H Bennett Production and utilization of high density plasma
US3431502A (en) * 1968-04-10 1969-03-04 Atomic Energy Commission Target positioner for accelerator external beam
US4428902A (en) * 1981-05-13 1984-01-31 Murray Kenneth M Coal analysis system
US4756866A (en) * 1985-10-09 1988-07-12 Alvarez Luis W Nitrogen detection
US5342283A (en) * 1990-08-13 1994-08-30 Good Roger R Endocurietherapy
US5784423A (en) * 1995-09-08 1998-07-21 Massachusetts Institute Of Technology Method of producing molybdenum-99

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
NATH ET AL., MEDICAL PHYSICS, vol. 3, no. 3, May 1976 (1976-05-01) - June 1976 (1976-06-01), pages 149 - 153, XP002932929 *
NORDELL ET AL., PHYS. MED. BIOL., vol. 29, no. 7, 1984, pages 797 - 810, XP002932930 *
SEKINE ET AL., APPL. RADIAT. ISOT., vol. 42, no. 2, 1991, pages 149 - 153, XP002932929 *

Also Published As

Publication number Publication date
AU4180799A (en) 1999-11-01
JP2002511566A (en) 2002-04-16
WO1999052587A2 (en) 1999-10-21
EP1087814A2 (en) 2001-04-04
CA2327824A1 (en) 1999-10-21

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