WO1999051142A3 - Non-invasive tissue glucose level monitoring - Google Patents

Non-invasive tissue glucose level monitoring Download PDF

Info

Publication number
WO1999051142A3
WO1999051142A3 PCT/US1999/007565 US9907565W WO9951142A3 WO 1999051142 A3 WO1999051142 A3 WO 1999051142A3 US 9907565 W US9907565 W US 9907565W WO 9951142 A3 WO9951142 A3 WO 9951142A3
Authority
WO
WIPO (PCT)
Prior art keywords
glucose level
level monitoring
tissue glucose
invasive tissue
invasive
Prior art date
Application number
PCT/US1999/007565
Other languages
French (fr)
Other versions
WO1999051142A2 (en
Inventor
Nikiforos Kollias
Wei Dong Tian
Jenny E Freeman
Original Assignee
Gen Hospital Corp
Nikiforos Kollias
Wei Dong Tian
Jenny E Freeman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp, Nikiforos Kollias, Wei Dong Tian, Jenny E Freeman filed Critical Gen Hospital Corp
Priority to EP99915314A priority Critical patent/EP1069857A2/en
Priority to JP2000541918A priority patent/JP2002510515A/en
Priority to AU33859/99A priority patent/AU766166B2/en
Priority to CA002322573A priority patent/CA2322573A1/en
Publication of WO1999051142A2 publication Critical patent/WO1999051142A2/en
Publication of WO1999051142A3 publication Critical patent/WO1999051142A3/en
Priority to US11/224,690 priority patent/US7899518B2/en
Priority to US13/037,348 priority patent/US20120053429A1/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14532Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring glucose, e.g. by tissue impedance measurement

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pathology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Optics & Photonics (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Emergency Medicine (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

Instruments and methods for performing non-invasive measurements of analyte concentrations and for monitoring, analysing and regulating tissue status, such as tissue glucose levels.
PCT/US1999/007565 1998-04-06 1999-04-06 Non-invasive tissue glucose level monitoring WO1999051142A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP99915314A EP1069857A2 (en) 1998-04-06 1999-04-06 Non-invasive tissue glucose level monitoring
JP2000541918A JP2002510515A (en) 1998-04-06 1999-04-06 Non-invasive tissue glucose level monitoring
AU33859/99A AU766166B2 (en) 1998-04-06 1999-04-06 Non-invasive tissue glucose level monitoring
CA002322573A CA2322573A1 (en) 1998-04-06 1999-04-06 Non-invasive tissue glucose level monitoring
US11/224,690 US7899518B2 (en) 1998-04-06 2005-09-12 Non-invasive tissue glucose level monitoring
US13/037,348 US20120053429A1 (en) 1998-04-06 2011-02-28 Non-Invasive Tissue Glucose-Level Monitoring

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8079498P 1998-04-06 1998-04-06
US60/080,794 1998-04-06

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US09/287,486 A-371-Of-International US6505059B1 (en) 1998-04-06 1999-04-06 Non-invasive tissue glucose level monitoring
US09/785,547 Continuation-In-Part US6721582B2 (en) 1998-04-06 2001-02-20 Non-invasive tissue glucose level monitoring

Publications (2)

Publication Number Publication Date
WO1999051142A2 WO1999051142A2 (en) 1999-10-14
WO1999051142A3 true WO1999051142A3 (en) 2000-02-17

Family

ID=22159651

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/007565 WO1999051142A2 (en) 1998-04-06 1999-04-06 Non-invasive tissue glucose level monitoring

Country Status (5)

Country Link
EP (1) EP1069857A2 (en)
JP (1) JP2002510515A (en)
AU (1) AU766166B2 (en)
CA (1) CA2322573A1 (en)
WO (1) WO1999051142A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8834020B2 (en) 2003-04-22 2014-09-16 Geelux Holdings, Ltd. Thermal imaging system
US9119530B2 (en) 2005-10-24 2015-09-01 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544193B2 (en) 1996-09-04 2003-04-08 Marcio Marc Abreu Noninvasive measurement of chemical substances
US6728560B2 (en) 1998-04-06 2004-04-27 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US6721582B2 (en) 1999-04-06 2004-04-13 Argose, Inc. Non-invasive tissue glucose level monitoring
US6505059B1 (en) * 1998-04-06 2003-01-07 The General Hospital Corporation Non-invasive tissue glucose level monitoring
US7899518B2 (en) 1998-04-06 2011-03-01 Masimo Laboratories, Inc. Non-invasive tissue glucose level monitoring
HU226183B1 (en) 1999-08-26 2008-06-30 Novartis Ag Ophthalmic lens and sensor system for measuring the concentration of an analyte in an ocular fluid
CA2389450A1 (en) * 1999-11-03 2001-05-10 Argose,Inc. Interface medium for tissue surface probe
US6639668B1 (en) 1999-11-03 2003-10-28 Argose, Inc. Asynchronous fluorescence scan
EP1257192A1 (en) 2000-02-18 2002-11-20 Argose, Inc. Generation of spatially-averaged excitation-emission map in heterogeneous tissue
US7139598B2 (en) * 2002-04-04 2006-11-21 Veralight, Inc. Determination of a measure of a glycation end-product or disease state using tissue fluorescence
US7043288B2 (en) * 2002-04-04 2006-05-09 Inlight Solutions, Inc. Apparatus and method for spectroscopic analysis of tissue to detect diabetes in an individual
US6549796B2 (en) * 2001-05-25 2003-04-15 Lifescan, Inc. Monitoring analyte concentration using minimally invasive devices
US8849379B2 (en) 2002-04-22 2014-09-30 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
US9848815B2 (en) 2002-04-22 2017-12-26 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters
KR101205935B1 (en) 2002-04-22 2012-11-28 마시오 마크 아우렐리오 마틴스 애브리우 A support structure for placement on the skin at end of a brain temperature turnel
US7181219B2 (en) 2003-05-22 2007-02-20 Lucent Technologies Inc. Wireless handover using anchor termination
US10227063B2 (en) 2004-02-26 2019-03-12 Geelux Holdings, Ltd. Method and apparatus for biological evaluation
DE102006026173A1 (en) * 2006-06-06 2007-12-20 Fachhochschule Südwestfalen Non-invasive diagnosis of diabetes, early stage diabetes or diabetic risk, comprises determining analytes from amino acids, glycation product and/or ketone bodies in the test skin and comparing this value with the analyte of healthy skin
WO2009131989A2 (en) * 2008-04-21 2009-10-29 Drexel University Methods for measuring changes in optical properties of wound tissue and correlating near infrared absorption (fnir) and diffuse reflectance spectroscopy scattering (drs) with tissue neovascularization and collagen concentration to determine whether wound is healing
JP5394501B2 (en) * 2009-10-02 2014-01-22 シャープ株式会社 Blood vessel condition monitoring method
WO2011114578A1 (en) * 2010-03-19 2011-09-22 シャープ株式会社 Measurement device, measurement method, measurement result processing device, measurement system, measurement result processing method, control program, and recording medium
CN103167830B (en) * 2010-06-18 2016-08-31 代克诺普提克斯控股有限公司 For the method and apparatus determining the autofluorescence value of skin histology
KR101243183B1 (en) 2011-04-08 2013-03-14 한국전기연구원 Apparatus for measurement of autofluorescence of advanced glycation end products
WO2015054681A1 (en) 2013-10-11 2015-04-16 Marcio Marc Abreu Method and apparatus for biological evaluation
US10335040B2 (en) 2014-01-10 2019-07-02 Geelux Holdings, Ltd. Device for measuring the infrared output of the Abreu brain thermal tunnel
US10251776B2 (en) 2014-01-10 2019-04-09 Geelux Holding, Ltd. Devices configured to monitor biological parameters, and to provide treatment, at an Abreu brain thermal tunnel
AU2015209304A1 (en) 2014-01-22 2016-07-21 Marcio Marc Abreu Devices configured to provide treatment at an Abreu brain thermal tunnel
JP2017517254A (en) * 2014-05-21 2017-06-29 エンパイア テクノロジー ディベロップメント エルエルシー Tattoos and tattoo applicators for animal life cycle monitoring
JP2018512915A (en) 2015-03-10 2018-05-24 マーシオ マーク アブリュー Device, apparatus, system and method for measuring temperature at ABTT termination
JP6156804B2 (en) * 2015-06-09 2017-07-05 シャープライフサイエンス株式会社 Aging evaluation equipment
WO2017115361A1 (en) * 2015-12-31 2017-07-06 Wear2B Ltd Device, system and method for non-invasive monitoring of physiological measurements
JP2018105761A (en) * 2016-12-27 2018-07-05 東亜ディーケーケー株式会社 Multi-wavelength fluorescence analyzer
JP2018146539A (en) * 2017-03-09 2018-09-20 東亜ディーケーケー株式会社 Multi-wavelength fluorescence analyzer
JP7187489B2 (en) * 2017-05-22 2022-12-12 ブロリス センサー テクノロジー,ユーエイビー Tunable Hybrid III-V/IV Laser Sensor System-on-Chip for Real-Time Monitoring of Blood Component Concentration Levels
JP2020106318A (en) * 2018-12-26 2020-07-09 メディカルフォトニクス株式会社 Absorbed calorie measuring device, absorbed calorie measuring method, and absorbed calorie measuring program
CN112641429A (en) * 2020-12-24 2021-04-13 上海百雀羚生物科技有限公司 Method for detecting antioxidant efficacy

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3837339A (en) * 1972-02-03 1974-09-24 Whittaker Corp Blood glucose level monitoring-alarm system and method therefor
US4979509A (en) * 1989-07-19 1990-12-25 Northstar Research Institute, Ltd. Continuous glucose monitoring and a system utilized therefor
US5341805A (en) * 1993-04-06 1994-08-30 Cedars-Sinai Medical Center Glucose fluorescence monitor and method
EP0623307A1 (en) * 1993-05-07 1994-11-09 Diasense, Inc. Non-invasive determination of constituent concentration using non-continuous radiation
WO1995006431A2 (en) * 1993-08-24 1995-03-09 Robinson Mark R A robust accurate non-invasive analyte monitor
EP0663591A1 (en) * 1993-12-16 1995-07-19 I.S.S. (U.S.A.) Inc. Photosensor with multiple light sources
US5507288A (en) * 1994-05-05 1996-04-16 Boehringer Mannheim Gmbh Analytical system for monitoring a substance to be analyzed in patient-blood
US5553616A (en) * 1993-11-30 1996-09-10 Florida Institute Of Technology Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discriminator

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3837339A (en) * 1972-02-03 1974-09-24 Whittaker Corp Blood glucose level monitoring-alarm system and method therefor
US4979509A (en) * 1989-07-19 1990-12-25 Northstar Research Institute, Ltd. Continuous glucose monitoring and a system utilized therefor
US5341805A (en) * 1993-04-06 1994-08-30 Cedars-Sinai Medical Center Glucose fluorescence monitor and method
EP0623307A1 (en) * 1993-05-07 1994-11-09 Diasense, Inc. Non-invasive determination of constituent concentration using non-continuous radiation
WO1995006431A2 (en) * 1993-08-24 1995-03-09 Robinson Mark R A robust accurate non-invasive analyte monitor
US5553616A (en) * 1993-11-30 1996-09-10 Florida Institute Of Technology Determination of concentrations of biological substances using raman spectroscopy and artificial neural network discriminator
EP0663591A1 (en) * 1993-12-16 1995-07-19 I.S.S. (U.S.A.) Inc. Photosensor with multiple light sources
US5507288A (en) * 1994-05-05 1996-04-16 Boehringer Mannheim Gmbh Analytical system for monitoring a substance to be analyzed in patient-blood
US5507288B1 (en) * 1994-05-05 1997-07-08 Boehringer Mannheim Gmbh Analytical system for monitoring a substance to be analyzed in patient-blood

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8834020B2 (en) 2003-04-22 2014-09-16 Geelux Holdings, Ltd. Thermal imaging system
US9119530B2 (en) 2005-10-24 2015-09-01 Geelux Holdings, Ltd. Apparatus and method for measuring biologic parameters

Also Published As

Publication number Publication date
AU3385999A (en) 1999-10-25
EP1069857A2 (en) 2001-01-24
JP2002510515A (en) 2002-04-09
CA2322573A1 (en) 1999-10-14
WO1999051142A2 (en) 1999-10-14
AU766166B2 (en) 2003-10-09

Similar Documents

Publication Publication Date Title
WO1999051142A3 (en) Non-invasive tissue glucose level monitoring
AU4694499A (en) Trace level detection of analytes using artificial olfactometry
WO2005007215A3 (en) Method and apparatus for tissue oximetry
WO2002010725A3 (en) Method for non-invasively determining the concentration of an analyte by compensating for the effect of tissue hydration
WO2001060246A3 (en) Multivariate analysis of green to ultraviolet spectra of cell and tissue samples
CA2330629A1 (en) Method and device for predicting physiological values
EP1260815A3 (en) Methods for automatically monitoring analyte concentration using minimally invasive devices
WO2002026113A3 (en) Method and apparatus for determining pulse oximetry differential values
WO2004063713A3 (en) Non-invasive determination of direction and rate of change of an analyte
PL354423A1 (en) Method of biological fluid sampling and making corresponding analyte measurements as well as an electrochemical cell, apparatus and system therefor
MXPA02011478A (en) Stabilized tetrazolium-phenazine reagent compositions and methods for using the same.
WO2000049941A8 (en) Glucose monitor calibration methods
WO2002057740A3 (en) Use of targeted glycemic profiles in the calibration of a noninvasive blood glucose monitor
WO2002026122A8 (en) Minimizing spectral effects during nir-based blood analyte determination
WO2006127694A3 (en) Analyte sensor
WO2006039310A3 (en) Blood monitoring system
WO2000018954A3 (en) Use of pex in the treatment of metabolic bone diseases
WO2007064576A3 (en) Blood monitoring system
WO2003069308A3 (en) Method of determining an analyte concentration in a sample from an absorption spectrum
WO2003087759A3 (en) Non-invasive spectroscopic measurement of analytes using a matched reference analyte
WO2001087137A3 (en) Implantable sensor
CA2332112A1 (en) Monitoring of physiological analytes
DE69903898T2 (en) Test strips for the visual determination of blood glucose concentration
IL155349A0 (en) Analyte concentration determination devices and methods of using the same
WO2002040634A3 (en) Expression miniarrays and uses thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SL SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

WWE Wipo information: entry into national phase

Ref document number: 33859/99

Country of ref document: AU

ENP Entry into the national phase

Ref document number: 2322573

Country of ref document: CA

Ref country code: CA

Ref document number: 2322573

Kind code of ref document: A

Format of ref document f/p: F

ENP Entry into the national phase

Ref country code: JP

Ref document number: 2000 541918

Kind code of ref document: A

Format of ref document f/p: F

NENP Non-entry into the national phase

Ref country code: KR

WWE Wipo information: entry into national phase

Ref document number: 1999915314

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1999915314

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWG Wipo information: grant in national office

Ref document number: 33859/99

Country of ref document: AU

WWW Wipo information: withdrawn in national office

Ref document number: 1999915314

Country of ref document: EP