WO1999040957A1 - Method of and apparatus for navigating medical devices in body lumens - Google Patents
Method of and apparatus for navigating medical devices in body lumens Download PDFInfo
- Publication number
- WO1999040957A1 WO1999040957A1 PCT/US1998/002835 US9802835W WO9940957A1 WO 1999040957 A1 WO1999040957 A1 WO 1999040957A1 US 9802835 W US9802835 W US 9802835W WO 9940957 A1 WO9940957 A1 WO 9940957A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- guide wire
- distal end
- medical device
- lumen
- magnetic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/0105—Steering means as part of the catheter or advancing means; Markers for positioning
- A61M25/0127—Magnetic means; Magnetic markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/06—Devices, other than using radiation, for detecting or locating foreign bodies ; determining position of probes within or on the body of the patient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B6/00—Apparatus for radiation diagnosis, e.g. combined with radiation therapy equipment
- A61B6/12—Devices for detecting or locating foreign bodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
- A61M25/09—Guide wires
- A61M2025/09175—Guide wires having specific characteristics at the distal tip
Definitions
- This invention relates to a method of, and apparatus for, navigating medical devices in body lumens, such as in blood vessels, the trachea, the gastrointestinal tract, or the urinary tract.
- vascular catheterizations and interventional neuroradiology procedures involve the introduction of medical devices through the arteries; bronchoscopies involve the introduction of medical devices through the trachea; endoscopies and colonoscopies involve the introduction of instruments through the gastrointestinal tract; and urethroscopies involve the introduction of medical devices through the urinary tract .
- bronchoscopies involve the introduction of medical devices through the trachea; endoscopies and colonoscopies involve the introduction of instruments through the gastrointestinal tract; and urethroscopies involve the introduction of medical devices through the urinary tract .
- Numerous methods and apparatus have been developed for introducing medical devices in the body. Many of these methods employ guide wires for remotely controlling the orientation of the tip of the medical device as it is advanced in the body lumen.
- the methods and apparatuses of the present invention involve magnetically guiding a medical device through a lumen in the body.
- a magnet is provided on the end of a guide wire and an externally applied magnetic field orients the magnet in the body lumen.
- the magnet can be advanced through the body lumen by manipulating the magnetic field or by pushing the guide wire.
- a catheter may be disposed over a guide wire having a magnet on its distal end.
- the guide wire and catheter combination is introduced into a body lumen through a natural or surgically formed opening. Once in the body the guide wire and catheter combination is navigated through the body lumen by applying a magnetic field, which acts on the distal end of the guide wire, orienting it.
- the guide wire is advanced slightly ahead of the catheter at a branch in the body lumen, and a magnetic field is applied to orient the tip of the guide wire, and the guide wire is advanced in the direction of the tip which is oriented into the selected branch.
- the guide wire can be advanced by the application of the magnetic field, by pushing at the proximal end, or by both.
- the catheter is then advanced over the guide wire. This process is repeated until the distal end of the catheter is at its desired location. Once the distal end of the catheter is in the desired position, the magnet can be withdrawn through the lumen of the catheter by pulling on the tether. Treatment, such as drug therapy or embolizing agents, can then be passed through the catheter.
- a guide wire with a magnet on the tip may be docked at the distal end of the lumen inside a catheter or other medical device .
- the guide wire and catheter combination is introduced into a body lumen through a natural or surgically formed opening. Once in the body lumen, the guide wire and catheter combination is navigated through the body lumen by applying a magnetic field, which acts upon the magnet-tipped guide wire in the catheter, orienting it.
- the catheter is advanced by pushing the guide wire. Once the distal end of the catheter is in the desired location, the guide wire can be withdrawn through the lumen of the catheter by pulling on the guide wire. Treatment, such as drug therapy or embolizing agents, can then be passed through the catheter.
- the methods of the various embodiments of this invention, and the guide wire of the various embodiments of this invention facilitate quick, easy and accurate positioning of a catheter or other medical device via a body lumen. Once the catheter is properly positioned, it can be used during a diagnostic or therapeutic procedure, either directly or as a passage for other medical devices .
- Fig. 1 is a longitudinal cross-sectional view of a guide wire and catheter combination constructed according to the principles of a first embodiment this invention
- Fig. 2 is a plan view of the guide wire of the first embodiment
- Fig. 3 is an enlarged cross-sectional view of the distal tip of the guide wire
- Fig. 4 is an enlarged cross sectional view of the distal end of the guide wire using a socket to secure the magnet ;
- Fig. 5 is an enlarged cross sectional view of the distal end of the guide wire using a collar to secure the magnet .
- Fig. 6 is an enlarged cross-sectional view of a first alternate construction of the distal section of the guide wire
- Fig. 7 is an enlarged cross-sectional view of a second alternate construction of the distal section of the guide wire;
- Fig. 8 is an side elevation view of a third alternate construction of the distal section of the guide wire;
- Fig. 8a is a side elevation view of the third alternate construction of the distal section of the guide wire, in a magnetic field
- Fig. 9 is a side elevation view of a fourth alternate construction of the distal section of the guide wire.
- Fig. 9a is a side elevation view of the fourth alternate construction of the distal tip of the guide wire, in a magnetic field
- Fig. 10 is a longitudinal cross-sectional view of the guide wire and endoscope combination constructed according to the principles of the first embodiment of this invention.
- Fig. 11 is a longitudinal cross-sectional view of a guide wire and catheter combination according a second embodiment of this invention.
- Fig. 12 is a longitudinal cross-sectional view of a guide wire and catheter combination with the guide wire partially withdrawn from the lumen of the catheter;
- Fig. 13 is a side elevation view of a guide wire and biopsy device according to the principles of the present invention.
- a guide wire and magnet combination constructed according to the principles of a first embodiment of this invention is indicated generally as 20 in Fig. 1.
- the guide wire and catheter combination 20 comprises a guide wire 22 and a catheter 24.
- the guide wire 22 comprises a wire 26, which is preferably made of nitinol, which is 6 highly flexible and resists kinking, although the guide wire could be made of some other suitable material.
- a magnet 28 is mounted on the distal end 30 of the guide wire 22. This magnet may either be a permanent magnet or a permeable magnetic material. A permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field.
- the magnet 28 is made of NdFeB (neodymium-iron-boron) or samarium cobalt and is sized to respond to the magnetic field that will be applied to orient the guide wire 22 in the body lumen and to be retracted through the catheter 24.
- the magnet 28 is preferably elongate so that it can orient the tip of the guide wire 22 in the presence of an applied magnetic field. Magnets of about 0.4 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and a length of about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) are sufficiently large for use in navigating a guide wire.
- the magnet is preferably a cylindrical body 34 with an axial bore 36 therethrough.
- the distal end of the guide wire 22 extends through the bore, and is secured with a bead 38 of adhesive on the distal side of the magnet 28.
- the bead 38 also provides a rounded head on the distal end 30 of the guide wire 22.
- the magnet 28 could also be attached to the distal end of the guide wire 22 with a socket 39 formed on the end of the guide wire.
- the socket 39 can be crimped into the distal end of the magnet 28, and/or the magnet can be secured with adhesive.
- the magnet 28 could also be secured by first attaching a collar 41 to the end of the guide wire 22.
- the magnet 28 can be secured to the collar 41 by adhesive or by fusion.
- the catheter 24 is preferably of conventional construction, having a proximal end 40, a distal end 42, and a lumen 44 extending therebetween.
- the catheter 24 can be made of polyurethane tubing, or some other suitable material.
- the size of the catheter 24 depends upon where in the body it will be introduced, and how it will be used. For example, for use in the blood vessels in the brain, the catheter might have an outside diameter of about 0.7 mm (0.03 inches), an inside diameter of about 0.6 mm (0.02 inches), and a length of about 2m (6.6 feet) .
- the guide wire 22 can be introduced into a body lumen, such as a blood vessel, and navigated to its desired location by the controlled application of magnetic fields.
- the application of a magnetic field allows the operator to steer the distal end of the guide wire 22 by orienting the distal end of the guide wire to the desired direction of travel.
- the guide wire 22 can be advanced using the magnetic field, or the guide wire can be advanced by pushing the proximal end. As the guide wire advances, the catheter 24 can be advanced over the guide wire 22, until the catheter is in its desired location.
- a first alternate construction of the guide wire 22' can be provided with a tapering collar 46.
- the collar 46 facilitates withdrawing the magnet 28 through the distal end 42 of the catheter 24.
- the collar can be made of a platinum so that the position of the end of the guide wire can be easily located on an x-ray.
- the magnetic articulation of the distal end of the guide wire eliminates the need to provide a permanent 8 bend in the guide wire in order to navigate through branches in body lumens.
- the straight configuration permitted by the guide wires of the present invention permits faster and easier navigation on straight sections and reduces unintentional diversion down branches of the lumen.
- a second alternate construction of the guide wire 22" has a sheath 48, made of flexible polyurethane tubing, extending over the wire 26.
- the sheath 48 preferably has the same outside diameter as the magnet 28, to smoothly slide in the lumen 44, and to help prevent the excessive movement of the guide wire 22 within the lumen.
- the sheath 48 is preferably secured to the proximal end of the magnet 28 with an adhesive, such as SICOMET 40 available from Tracon.
- guide wire 50 has a series of spaced magnets 52 on the distal end portion 54 of the wire 56.
- the magnets 52 are preferably similar in construction to magnet 28, comprising a generally cylindrical body 58, each having an axial bore 60 extending therethrough.
- the distal portion of the wire 56 extends through the bores 60, and the magnets 52 are secured to the wire 56 in spaced apart relation with adhesive.
- the magnets 52 are preferably made from NdFeB, and have a diameter of 2 mm (0.08 inches) and are 4 mm (0.16 inches) long.
- the magnets 52 are preferably spaced over the distal 5 cm (2 inches) of the guide wire 50, and are spaced 1cm (0.4 inches) on center. Of course some other size magnets and/or different magnet spacing could be used. Moreover the spacing of the magnets does not have to be equal . This alternate construction is particularly useful for an electrophysiology catheter where the magnetic fields could pull or shape the guide wire 50 to the heart wall .
- the magnets 52 on the distal end portion 54 of guide wire 50 cause the guide wire to assume a particular shape dictated by the field.
- the shape of the distal portion of the guide wire can be controlled, facilitating the navigation through, or shaping to, the body lumen.
- the guide wire 50 can be pulled by magnet force on the magnets 52, or the distal end can be manually pushed. The pull force could be used to hold the catheter with guide wire to the wall of a body lumen.
- a fourth alternative construction of the guide wire of the first embodiment is indicated as 62 in Fig. 9.
- the distal end portion 64 of guide wire 62 is made from a magnetic material.
- the distal end portion 64 is preferably about 0.25 mm (0.01 inches) in diameter, and about 1 cm (0.4 inches) long.
- the distal end portion is can be made of a permeable magnetic material such as a steel or a magnetic stainless steel wire, or a steel or a magnetic stainless steel braid.
- the distal end portion 64 of guide wire 62 assumes a particular orientation dictated by the field.
- the guide wire 62 can be advanced by magnet force on the distal portion 48, or the proximal end can be pushed.
- the magnetic field can also function to selectively stiffen the distal end of the 10 guide wire, to facilitate navigation through the body lumen. This allows the guide wire to be designed with the minimum amount of stiffness to over come static friction when applying an axial pushing force on at the proximal end. Sufficient stiffness for navigation can be provided by applying a magnetic field to the distal tip.
- the guide wire 22 can be used to navigate an endoscope 66 through a body lumen, such as a colon.
- the endoscope 66 has a lumen 68 extending therethrough.
- a magnetic field is applied to orient the magnet 28 on the distal end of the guide wire with the magnetic field.
- the endoscope 66 can then be advanced over the guide wire, the lumen 68 sliding over the guide wire.
- the guide wire 22 is preferably incrementally advanced, and the endoscope is then advanced over the guide wire, until the endoscope reaches its desired location.
- a guide wire and catheter combination constructed according to a second embodiment of this invention is indicated generally as 100 in Figs. 11 and 12.
- the guide wire and catheter combination 100 comprises guide wire 102 and catheter 104.
- the guide wire 102 comprises a wire 106, preferably made of nitinol, which is highly flexible and resists kinking, although the guide wire could be made of some other suitable material .
- a magnet 108 is mounted on the distal end of the wire 106. This magnet may either be a permanent magnet or a permeable magnetic material .
- a permanent magnet is easier to orient under the application of a magnetic field, as described below, but a permeable magnetic material is easier to pull under the application of a magnetic field.
- the magnet 108 is made of NdFeB (neodymium-iron-boron) or samarian cobalt and is sized to respond to the magnetic field that will be applied to move the guide wire 102 through the body lumen.
- the magnet 108 is preferably elongate so that it 11 can orient the tip of the guide wire 102 in the presence of an applied magnetic field. Magnets of about 0.4 mm (0.02 inches) to about 0.7 mm (0.03 inches) in diameter, and a length of about 1 mm (0.04 inches) to 1.5 mm (0.06 inches) are sufficiently large for use in navigating a guide wire .
- the magnet is preferably a cylindrical body 110 with an axial bore 112 therethrough.
- the distal end of the guide wire 102 extends through the bore 112, and is secured with a bead 114 of adhesive on the distal side of the magnet 108.
- the bead 114 also provides a rounded head on the distal end of the guide wire 102.
- the guide wire 102 could have a plurality of spaced magnets on the distal end portion similar to guide wire 50, described above, or the distal end portion of the guide wire could be made of a flexible magnetic material similar to guide wire 62.
- the catheter 104 is preferably of conventional construction, having a proximal end 116, a distal end 118, and a lumen 120 extending therebetween.
- the catheter 104 can be made of polyurethane tubing, or some other suitable material.
- the size of the catheter 104 depends upon where in the body it will be introduced, and how it will be used. For example, for use in the blood vessels in the brain, the catheter might have an outside diameter of about 0.7 mm (0.13 inches), an inside diameter of about 0.6 mm (0.11 inches), and a length of about 2 m (6.5 feet) .
- the guide wire 102 is adapted to fit inside the lumen 120, and "dock" with the catheter 104.
- the distal end of the lumen 120 has a restriction 122 for engaging the distal end of the guide wire 102.
- This restriction is preferably formed by a annular flange 124 on ring 126 provided on the distal end of the catheter.
- the ring 126 can be made of tantalum. 12
- the guide wire and catheter combination 100 can be introduced into a body lumen, such as a blood vessel, and navigated to its desired position by the controlled application of magnetic fields.
- the application of a magnetic field allows the operator to steer the distal end of the guide wire 102 by orienting the distal end of the guide wire to the desired direction of travel.
- the guide wire 102 can be advanced using the magnetic field, or the guide wire can be advanced by pushing the proximal end. As the guide wire advances, the catheter 104 can be advanced.
- the guide wire 102 can be withdrawn through the lumen 120, and out the proximal end 116.
- the guide wire 102 can be used to navigate a biopsy tool 128 through a body lumen such as a kidney.
- the biopsy tool 128 has a lumen 130 therein.
- the distal end of the guide wire 102 is adapted to fit into the lumen 130 and "dock" with the biopsy tool.
- a magnetic field is applied to orient the magnet 108 inside the lumen 130 of the biopsy tool 128.
- the biopsy tool 128 can then be advanced, in the desired direction either by pushing the proximal end of the guide wire 102, of pulling the distal end of the guide wire with the magnetic field.
- the guide wire 102 can be withdrawn.
- the guide wires of either embodiment can be used to deliver catheter or other medical devices to locations within the body accessible via a body lumen.
- the guide wire could be used to navigate a device for retrieval of man made objects stents, or body made objects e.g. stones.
- the high degree of articulation of the tip provides the control needed to capture and recover such objects. 13
- the guide wire and catheter combination 20 of the first embodiment is introduced through a natural or surgically formed- opening in a body lumen.
- a magnetic field is applied to orient the distal tip within the vessel.
- the magnetic field can also be used to advance the distal tip of the guide wire, or the guide wire can be pushed to advance the guide wire in the body lumen.
- the catheter 24 can be advanced over the guide wire.
- the magnet 28 is removed from the catheter 24 by pulling the tether 26 to withdraw the magnet through the lumen 44 of the catheter.
- multiple catheters can be directed in the same general area to facilitate a medical procedure with independent control of the catheters .
- the guide wire 102 is inserted into the lumen of the catheter 104 (or other medical device) and the guide wire and catheter combination 100 of the second embodiment is introduced through an opening in a natural or surgically formed opening in a body lumen.
- a magnetic field is applied to orient the magnet 108 on the proximal end of the guide wire 102, inside the catheter 104.
- the guide wire and catheter are then advanced, either by applying a magnetic field, or by pushing the distal end of the guide wire.
- the guide wire 102 is removed from the catheter 104 by pulling the guide wire 102 to withdraw it from the lumen 120 of the catheter.
- the catheter 24 or 104 can be used for the administration of drug therapy or to 14 perform a medical procedure or it can be used as a guide to insert medical devices to the area surrounding the distal end of the catheter to perform a medical procedure .
- the magnet on the guide- wire can be removed from the treatment site, multiple catheters can be directed in the same general area to facilitate a medical procedure withindependent control of the catheters.
- the magnet could be left in place within the catheter, if desired.
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1998/002835 WO1999040957A1 (en) | 1998-02-17 | 1998-02-17 | Method of and apparatus for navigating medical devices in body lumens |
AU61652/98A AU6165298A (en) | 1998-02-17 | 1998-02-17 | Method of and apparatus for navigating medical devices in body lumens |
US09/200,055 US7066924B1 (en) | 1997-11-12 | 1998-11-25 | Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip |
US11/475,840 US20070021731A1 (en) | 1997-11-12 | 2006-06-27 | Method of and apparatus for navigating medical devices in body lumens |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US1998/002835 WO1999040957A1 (en) | 1998-02-17 | 1998-02-17 | Method of and apparatus for navigating medical devices in body lumens |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US08/969,165 Continuation-In-Part US5931818A (en) | 1997-08-29 | 1997-11-12 | Method of and apparatus for intraparenchymal positioning of medical devices |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US09/200,055 Continuation-In-Part US7066924B1 (en) | 1997-11-12 | 1998-11-25 | Method of and apparatus for navigating medical devices in body lumens by a guide wire with a magnetic tip |
US11/475,840 Continuation-In-Part US20070021731A1 (en) | 1997-11-12 | 2006-06-27 | Method of and apparatus for navigating medical devices in body lumens |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1999040957A1 true WO1999040957A1 (en) | 1999-08-19 |
Family
ID=22266388
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/002835 WO1999040957A1 (en) | 1997-11-12 | 1998-02-17 | Method of and apparatus for navigating medical devices in body lumens |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU6165298A (en) |
WO (1) | WO1999040957A1 (en) |
Cited By (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001093938A1 (en) * | 2000-06-08 | 2001-12-13 | Oxford Instruments Plc | Catheter guide assembly |
WO2002043797A1 (en) | 2000-11-29 | 2002-06-06 | Oxford Instruments Plc | Catheter steering apparatus and method |
EP1631188A4 (en) * | 2003-05-21 | 2009-01-21 | Stereotaxis Inc | Electrophysiology catheter |
EP2361545A1 (en) | 2005-01-06 | 2011-08-31 | G.I. View Ltd. | Gastrointestinal tool over guiding element |
ITMI20111820A1 (en) * | 2011-10-06 | 2013-04-07 | Enrico Giustiniano | ASSISTIVE DEVICE FOR ORO-TRACHEAL INTUBATION |
US8617150B2 (en) | 2010-05-14 | 2013-12-31 | Liat Tsoref | Reflectance-facilitated ultrasound treatment |
US8956346B2 (en) | 2010-05-14 | 2015-02-17 | Rainbow Medical, Ltd. | Reflectance-facilitated ultrasound treatment and monitoring |
US9242122B2 (en) | 2010-05-14 | 2016-01-26 | Liat Tsoref | Reflectance-facilitated ultrasound treatment and monitoring |
US9707414B2 (en) | 2012-02-14 | 2017-07-18 | Rainbow Medical Ltd. | Reflectance-facilitated ultrasound treatment and monitoring |
US9770593B2 (en) | 2012-11-05 | 2017-09-26 | Pythagoras Medical Ltd. | Patient selection using a transluminally-applied electric current |
US10004557B2 (en) | 2012-11-05 | 2018-06-26 | Pythagoras Medical Ltd. | Controlled tissue ablation |
WO2018130956A1 (en) * | 2017-01-12 | 2018-07-19 | Special Electronic Design S.R.L. | Endoscopic guide, in particular for colonoscopy, and system for endoscopy comprising such a guide |
US10080481B2 (en) | 2005-02-10 | 2018-09-25 | G.I. View Ltd. | Advancement techniques for gastrointestinal tool with guiding element |
US10226600B2 (en) | 2008-07-30 | 2019-03-12 | G.I. View Ltd. | System and method for enhanced maneuverability |
US10383685B2 (en) | 2015-05-07 | 2019-08-20 | Pythagoras Medical Ltd. | Techniques for use with nerve tissue |
CN110354365A (en) * | 2019-07-10 | 2019-10-22 | 郑州大学第一附属医院 | Intubation intervention device in cardiovascular interventional operation |
US10478249B2 (en) | 2014-05-07 | 2019-11-19 | Pythagoras Medical Ltd. | Controlled tissue ablation techniques |
US11278189B2 (en) | 2017-01-12 | 2022-03-22 | Endostart S.r.l. | Endoscopic guide including anchoring head that accommodates a magnetic or ferromagnetic agent |
US11678932B2 (en) | 2016-05-18 | 2023-06-20 | Symap Medical (Suzhou) Limited | Electrode catheter with incremental advancement |
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Publication number | Priority date | Publication date | Assignee | Title |
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WO2001093938A1 (en) * | 2000-06-08 | 2001-12-13 | Oxford Instruments Plc | Catheter guide assembly |
WO2002043797A1 (en) | 2000-11-29 | 2002-06-06 | Oxford Instruments Plc | Catheter steering apparatus and method |
EP1631188A4 (en) * | 2003-05-21 | 2009-01-21 | Stereotaxis Inc | Electrophysiology catheter |
EP2361545A1 (en) | 2005-01-06 | 2011-08-31 | G.I. View Ltd. | Gastrointestinal tool over guiding element |
US10080481B2 (en) | 2005-02-10 | 2018-09-25 | G.I. View Ltd. | Advancement techniques for gastrointestinal tool with guiding element |
US10226600B2 (en) | 2008-07-30 | 2019-03-12 | G.I. View Ltd. | System and method for enhanced maneuverability |
US8956346B2 (en) | 2010-05-14 | 2015-02-17 | Rainbow Medical, Ltd. | Reflectance-facilitated ultrasound treatment and monitoring |
US9242122B2 (en) | 2010-05-14 | 2016-01-26 | Liat Tsoref | Reflectance-facilitated ultrasound treatment and monitoring |
US8617150B2 (en) | 2010-05-14 | 2013-12-31 | Liat Tsoref | Reflectance-facilitated ultrasound treatment |
US9795450B2 (en) | 2010-05-14 | 2017-10-24 | Rainbow Medical Ltd. | Reflectance-facilitated ultrasound treatment and monitoring |
US9993666B2 (en) | 2010-05-14 | 2018-06-12 | Rainbow Medical Ltd. | Reflectance-facilitated ultrasound treatment and monitoring |
ITMI20111820A1 (en) * | 2011-10-06 | 2013-04-07 | Enrico Giustiniano | ASSISTIVE DEVICE FOR ORO-TRACHEAL INTUBATION |
US9707414B2 (en) | 2012-02-14 | 2017-07-18 | Rainbow Medical Ltd. | Reflectance-facilitated ultrasound treatment and monitoring |
US10004557B2 (en) | 2012-11-05 | 2018-06-26 | Pythagoras Medical Ltd. | Controlled tissue ablation |
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US10478249B2 (en) | 2014-05-07 | 2019-11-19 | Pythagoras Medical Ltd. | Controlled tissue ablation techniques |
US10383685B2 (en) | 2015-05-07 | 2019-08-20 | Pythagoras Medical Ltd. | Techniques for use with nerve tissue |
US11678932B2 (en) | 2016-05-18 | 2023-06-20 | Symap Medical (Suzhou) Limited | Electrode catheter with incremental advancement |
CN110121288A (en) * | 2017-01-12 | 2019-08-13 | 恩度起点有限责任公司 | Endoscope guiding piece, it is especially useful in colonoscopy, and endoscopic system is used for comprising this guiding piece |
WO2018130956A1 (en) * | 2017-01-12 | 2018-07-19 | Special Electronic Design S.R.L. | Endoscopic guide, in particular for colonoscopy, and system for endoscopy comprising such a guide |
JP2020505087A (en) * | 2017-01-12 | 2020-02-20 | エンドスタート・ソチエタ・ア・レスポンサビリタ・リミタータENDOSTART S.r.l. | Endoscope guides, especially for colonoscopy, and systems for endoscopes equipped with such guides |
EP3788947A1 (en) * | 2017-01-12 | 2021-03-10 | Endostart S.r.l. | Endoscopic guide, in particular for colonoscopy, and system for endoscopy comprising such a guide |
US11278189B2 (en) | 2017-01-12 | 2022-03-22 | Endostart S.r.l. | Endoscopic guide including anchoring head that accommodates a magnetic or ferromagnetic agent |
AU2018208034B2 (en) * | 2017-01-12 | 2022-10-20 | Endostart S.r.l. | Endoscopic guide, in particular for colonoscopy, and system for endoscopy comprising such a guide |
CN110121288B (en) * | 2017-01-12 | 2023-02-17 | 恩度起点有限责任公司 | Endoscopic guide, in particular for colonoscopy, and system for endoscopy comprising such a guide |
US10349817B2 (en) | 2017-01-12 | 2019-07-16 | Endostart S.r.l. | Method for introducing colonoscope using endoscopic guide |
CN110354365A (en) * | 2019-07-10 | 2019-10-22 | 郑州大学第一附属医院 | Intubation intervention device in cardiovascular interventional operation |
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