WO1999031505A8 - Neurotrophic factor assay - Google Patents

Neurotrophic factor assay

Info

Publication number
WO1999031505A8
WO1999031505A8 PCT/US1998/025445 US9825445W WO9931505A8 WO 1999031505 A8 WO1999031505 A8 WO 1999031505A8 US 9825445 W US9825445 W US 9825445W WO 9931505 A8 WO9931505 A8 WO 9931505A8
Authority
WO
WIPO (PCT)
Prior art keywords
neurotrophic factor
assay
factor assay
screening
quantative
Prior art date
Application number
PCT/US1998/025445
Other languages
French (fr)
Other versions
WO1999031505A1 (en
Inventor
Charlotte M Mcguinness
Marthajoy Spano
George W Di Belenduik
Original Assignee
Shire Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shire Lab Inc filed Critical Shire Lab Inc
Publication of WO1999031505A1 publication Critical patent/WO1999031505A1/en
Publication of WO1999031505A8 publication Critical patent/WO1999031505A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides a cultured transformed glial cell based assay e.g. using cell line T98G for screening neurotrophic factors in physiologic sample. The assay is quantative and rapid, and is useful for screening columns fractions generated during the purification of growth factors.
PCT/US1998/025445 1997-12-15 1998-12-01 Neurotrophic factor assay WO1999031505A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US6946897P 1997-12-15 1997-12-15
US60/069,468 1997-12-15

Publications (2)

Publication Number Publication Date
WO1999031505A1 WO1999031505A1 (en) 1999-06-24
WO1999031505A8 true WO1999031505A8 (en) 1999-08-26

Family

ID=22089160

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/025445 WO1999031505A1 (en) 1997-12-15 1998-12-01 Neurotrophic factor assay

Country Status (1)

Country Link
WO (1) WO1999031505A1 (en)

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716930A (en) * 1991-04-10 1998-02-10 Ludwig Institute For Cancer Research Glial growth factors
GB9107566D0 (en) * 1991-04-10 1991-05-29 Ludwig Inst Cancer Res Glial mitogenic factors,their preparation and use
US5530109A (en) * 1991-04-10 1996-06-25 Ludwig Institute For Cancer Research DNA encoding glial mitogenic factors
GB9217316D0 (en) * 1992-08-14 1992-09-30 Ludwig Inst Cancer Res Schwann cell mitogenic factor,its preparation and use

Also Published As

Publication number Publication date
WO1999031505A1 (en) 1999-06-24

Similar Documents

Publication Publication Date Title
AU2245997A (en) Mutivariate sample analysis
AU3927597A (en) Covered sample well for use in nucleic acid assays and immunoassays
AU6177898A (en) Reagent dispenser and related test kit for biological specimens
AU622082B2 (en) Method for spectroscopic analysis of hydrocarbons, and hydrocarbon refining operations using same
AU6474898A (en) Microbiological test panel and method therefor
AU7129598A (en) Recombinant rabbit tissue factor based prothrombin time reagent
DE59814441D1 (en) USE OF CONTROL SURFACES FOR THE DETECTION OF DISTURBANCES IN A PROOF PROCESS
HUT67550A (en) Analitical kit and process for homocysteine assay
AU5964494A (en) Assays and kits for detecting analytes in the presence of cross-reacting substances
AU2597995A (en) Reagents and methods for the rapid and quantitative assay of pharmacological agents
AU4213396A (en) Kit for immunologically assaying biological substance and assay process
AU3268299A (en) Microbiological testing of a liquid sample
AU2661199A (en) Mammalian receptor proteins; related reagents and methods
AU2001294954A1 (en) Multi-well assay plate and plate holder and method of assembling the same
AU3574997A (en) Mammalian chemokine reagents
AU1785099A (en) Novel gene having reverse transcriptase motif
AU6312896A (en) Sample analyzer
AU7571998A (en) Rapid evaluation of the ratio of biological molecules
AU4553296A (en) Method and reagent for the specific determination of LDL in serum samples
AU2707597A (en) Method of assay
AU7322594A (en) Ndir gas analysis using spectral ratioing technique
AU2118097A (en) Sample holder for cells
AU5545399A (en) High throughput in vitro screening assay for modulators of nucleic acid helicases
WO1999031505A8 (en) Neurotrophic factor assay
AU2984192A (en) Colorimetric methods and reagents for the assay of calcium in a test sample

Legal Events

Date Code Title Description
AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
AL Designated countries for regional patents

Kind code of ref document: C1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

CFP Corrected version of a pamphlet front page

Free format text: REVISED ABSTRACT RECEIVED BY THE INTERNATIONAL BUREAU AFTER COMPLETION OF THE TECHNICAL PREPARATIONS FOR INTERNATIONAL PUBLICATION

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase