WO1999030718A3 - COMBINAISON DE PROSTAGLANDINES E2/F2α, DESTINEE AU TRAITEMENT DE L'IMPUISSANCE ET A L'ACCROISSEMENT DE L'EXCITATION SEXUELLE - Google Patents

COMBINAISON DE PROSTAGLANDINES E2/F2α, DESTINEE AU TRAITEMENT DE L'IMPUISSANCE ET A L'ACCROISSEMENT DE L'EXCITATION SEXUELLE Download PDF

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Publication number
WO1999030718A3
WO1999030718A3 PCT/US1998/026609 US9826609W WO9930718A3 WO 1999030718 A3 WO1999030718 A3 WO 1999030718A3 US 9826609 W US9826609 W US 9826609W WO 9930718 A3 WO9930718 A3 WO 9930718A3
Authority
WO
WIPO (PCT)
Prior art keywords
prostaglandin
sexual arousal
combination
treating
treating impotence
Prior art date
Application number
PCT/US1998/026609
Other languages
English (en)
Other versions
WO1999030718A2 (fr
Inventor
Nathan Earl Scott
Original Assignee
Nathan Earl Scott
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/992,946 external-priority patent/US5981593A/en
Priority claimed from US09/038,378 external-priority patent/US5962528A/en
Application filed by Nathan Earl Scott filed Critical Nathan Earl Scott
Priority to EP98963194A priority Critical patent/EP1059926A2/fr
Priority to CA002314369A priority patent/CA2314369A1/fr
Priority to AU18272/99A priority patent/AU1827299A/en
Publication of WO1999030718A2 publication Critical patent/WO1999030718A2/fr
Publication of WO1999030718A3 publication Critical patent/WO1999030718A3/fr
Priority to US09/422,031 priority patent/US6291528B1/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/557—Eicosanoids, e.g. leukotrienes or prostaglandins

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne un procédé et une composition de traitement du dysfonctionnement érectile chez l'homme ou du dysfonctionnement de l'excitation sexuelle chez la femme, ce procédé comprenant les étapes consistant à administrer au patient une dose unitaire d'une formulation comprenant une dose efficace d'une prostaglandine, à savoir la prostaglandine E1, la prostaglandine E2, ou des sels ou dérivés de celles-ci, acceptables sur le plan pharmacologique, la prostaglandine étant formulée à l'aide d'une petite dose de prostaglandine Fα2 et d'un milieu d'apport, acceptable sur le plan pharmacologique, et/ou d'un lubrifiant. Ce procédé concerne également la prostaglandine PGE2 formulée avec du mésylate de phentolamine, avec ou sans PGF2α.
PCT/US1998/026609 1991-07-03 1998-12-15 COMBINAISON DE PROSTAGLANDINES E2/F2α, DESTINEE AU TRAITEMENT DE L'IMPUISSANCE ET A L'ACCROISSEMENT DE L'EXCITATION SEXUELLE WO1999030718A2 (fr)

Priority Applications (4)

Application Number Priority Date Filing Date Title
EP98963194A EP1059926A2 (fr) 1997-12-18 1998-12-15 COMBINAISON DE PROSTAGLANDINES E 2?/F 2$g(a)?, DESTINEE AU TRAITEMENT DE L'IMPUISSANCE ET A L'ACCROISSEMENT DE L'EXCITATION SEXUELLE
CA002314369A CA2314369A1 (fr) 1997-12-18 1998-12-15 Combinaison de prostaglandines e2/f2.alpha., destinee au traitement de l'impuissance et a l'accroissement de l'excitation sexuelle
AU18272/99A AU1827299A (en) 1997-12-18 1998-12-15 Prostaglandin e2/f2alpha combination for treating impotence and enhancing sexual arousal
US09/422,031 US6291528B1 (en) 1991-07-03 1999-10-20 Prostaglandin E1/F2 in combination with prostaglandin F2α for enhancing female sexual arousal

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US08/992,946 1997-12-18
US08/992,946 US5981593A (en) 1991-07-03 1997-12-18 Prostaglandin E2 treatment of impotence
US508798A 1998-01-09 1998-01-09
US09/005,087 1998-01-09
US09/038,378 US5962528A (en) 1991-07-03 1998-03-11 Prostaglandin E2 /F2α combination for treating impotence
US09/038,378 1998-03-11

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
US09/038,378 Continuation-In-Part US5962528A (en) 1991-07-03 1998-03-11 Prostaglandin E2 /F2α combination for treating impotence

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US09/422,031 Continuation-In-Part US6291528B1 (en) 1991-07-03 1999-10-20 Prostaglandin E1/F2 in combination with prostaglandin F2α for enhancing female sexual arousal

Publications (2)

Publication Number Publication Date
WO1999030718A2 WO1999030718A2 (fr) 1999-06-24
WO1999030718A3 true WO1999030718A3 (fr) 1999-09-10

Family

ID=27357802

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/026609 WO1999030718A2 (fr) 1991-07-03 1998-12-15 COMBINAISON DE PROSTAGLANDINES E2/F2α, DESTINEE AU TRAITEMENT DE L'IMPUISSANCE ET A L'ACCROISSEMENT DE L'EXCITATION SEXUELLE

Country Status (5)

Country Link
EP (1) EP1059926A2 (fr)
CN (1) CN1282249A (fr)
AU (1) AU1827299A (fr)
CA (1) CA2314369A1 (fr)
WO (1) WO1999030718A2 (fr)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43372E1 (en) 1999-03-05 2012-05-08 Duke University C16 unsaturated FP-selective prostaglandins analogs
US8906962B2 (en) 2000-03-31 2014-12-09 Duke University Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US9346837B2 (en) 2000-03-31 2016-05-24 Duke University Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251436B1 (en) * 1995-09-29 2001-06-26 L.A.M. Pharmaceutical Corporation Drug preparations for treating sexual dysfunction
US6825234B2 (en) 1998-12-10 2004-11-30 Nexmed (Holdings) , Inc. Compositions and methods for amelioration of human female sexual dysfunction
AU3713600A (en) 1999-03-01 2000-09-21 Nitromed, Inc. Nitrosated and nitrosylated prostaglandins, compositions and metods of use
WO2000053148A2 (fr) * 1999-03-08 2000-09-14 Merck & Co., Inc. Procedes et compositions pour le traitement de la dyserection
IL139457A0 (en) * 1999-11-08 2001-11-25 Pfizer Compounds for the treatment of female sexual dysfunction
DK1280531T3 (da) * 2000-05-12 2007-05-29 Novalar Pharmaceuticals Inc Formulering bestående af phentolaminmesylat og anvendelse heraf
SE0100158D0 (sv) * 2001-01-19 2001-01-19 Synphora Ab Novel method and composition for local treatment of Meniere´s disease and tinnitus
AU2009301392B9 (en) * 2008-10-10 2018-05-24 Implantica Patent Ltd. Stimulation of sexually responsive tissue of the vulva
US9757330B2 (en) 2013-10-18 2017-09-12 Industrial Technology Research Institute Recipe for in-situ gel, and implant, drug delivery system formed thereby

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917864A (en) * 1973-02-12 1975-11-04 Sultanali M M Karim Use of prostaglandins E and F for induction of labor
US4005221A (en) * 1974-04-01 1977-01-25 Karim Sultanali M M Use of prostaglandins to induce menstruation
US4311707A (en) * 1979-02-12 1982-01-19 American Cyanamid Company Process for topically producing cutaneous vasodilation for the treatment of vasospastic or ischemic conditions
EP0357581A1 (fr) * 1988-09-02 1990-03-07 AMSU, Ltd. Composition pour le traitement de troubles de l'érection
WO1991016021A1 (fr) * 1990-04-25 1991-10-31 Alza Corporation Traitement de dysfonctionnement erectile
WO1993000894A1 (fr) * 1991-07-03 1993-01-21 Scott Nathan E Traitement de l'impuissance a l'aide de prostaglandine e2
US5242391A (en) * 1990-04-25 1993-09-07 Alza Corporation Urethral insert for treatment of erectile dysfunction
US5482039A (en) * 1994-03-25 1996-01-09 Vivus, Inc. Process for diagnosing erectile dysfunction, and related methods of treatment

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3917864A (en) * 1973-02-12 1975-11-04 Sultanali M M Karim Use of prostaglandins E and F for induction of labor
US4005221A (en) * 1974-04-01 1977-01-25 Karim Sultanali M M Use of prostaglandins to induce menstruation
US4311707A (en) * 1979-02-12 1982-01-19 American Cyanamid Company Process for topically producing cutaneous vasodilation for the treatment of vasospastic or ischemic conditions
EP0357581A1 (fr) * 1988-09-02 1990-03-07 AMSU, Ltd. Composition pour le traitement de troubles de l'érection
WO1991016021A1 (fr) * 1990-04-25 1991-10-31 Alza Corporation Traitement de dysfonctionnement erectile
US5242391A (en) * 1990-04-25 1993-09-07 Alza Corporation Urethral insert for treatment of erectile dysfunction
WO1993000894A1 (fr) * 1991-07-03 1993-01-21 Scott Nathan E Traitement de l'impuissance a l'aide de prostaglandine e2
US5482039A (en) * 1994-03-25 1996-01-09 Vivus, Inc. Process for diagnosing erectile dysfunction, and related methods of treatment

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE43372E1 (en) 1999-03-05 2012-05-08 Duke University C16 unsaturated FP-selective prostaglandins analogs
US8906962B2 (en) 2000-03-31 2014-12-09 Duke University Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US9346837B2 (en) 2000-03-31 2016-05-24 Duke University Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US9579270B2 (en) 2000-03-31 2017-02-28 Duke University Compositions and methods for treating hair loss using non-naturally occurring prostaglandins

Also Published As

Publication number Publication date
AU1827299A (en) 1999-07-05
EP1059926A2 (fr) 2000-12-20
WO1999030718A2 (fr) 1999-06-24
CN1282249A (zh) 2001-01-31
CA2314369A1 (fr) 1999-06-24

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