WO1999030131A1 - Test d'immunocapture fluorescent en une etape - Google Patents

Test d'immunocapture fluorescent en une etape Download PDF

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Publication number
WO1999030131A1
WO1999030131A1 PCT/US1998/007079 US9807079W WO9930131A1 WO 1999030131 A1 WO1999030131 A1 WO 1999030131A1 US 9807079 W US9807079 W US 9807079W WO 9930131 A1 WO9930131 A1 WO 9930131A1
Authority
WO
WIPO (PCT)
Prior art keywords
zone
sample
analyte
solid support
support matrix
Prior art date
Application number
PCT/US1998/007079
Other languages
English (en)
Inventor
Allan D. Pronovost
Alan M. Nelson
Christian Bobritchi
Original Assignee
Quidel Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quidel Corporation filed Critical Quidel Corporation
Priority to EP98915407A priority Critical patent/EP1046027A1/fr
Publication of WO1999030131A1 publication Critical patent/WO1999030131A1/fr

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/585—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with a particulate label, e.g. coloured latex
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • G01N33/54386—Analytical elements
    • G01N33/54387—Immunochromatographic test strips
    • G01N33/54388—Immunochromatographic test strips based on lateral flow
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
    • G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/74—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving hormones or other non-cytokine intercellular protein regulatory factors such as growth factors, including receptors to hormones and growth factors
    • G01N33/76—Human chorionic gonadotropin including luteinising hormone, follicle stimulating hormone, thyroid stimulating hormone or their receptors

Abstract

L'invention concerne un dosage immunologique servant à détecter la présence d'un analyte dans une solution d'échantillon. Le dosage immunologique comporte une matrice sur support solide de nitrocellulose comportant une zone d'échantillon, une zone de marqueur et une zone de capture. Une solution de billes de latex fluroescentes comportant un chélate de lanthanide en association avec des anticorps dirigés contre l'analyte cible est placée sur la zone de marqueur.
PCT/US1998/007079 1997-12-11 1998-04-10 Test d'immunocapture fluorescent en une etape WO1999030131A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
EP98915407A EP1046027A1 (fr) 1997-12-11 1998-04-10 Test d'immunocapture fluorescent en une etape

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US98924997A 1997-12-11 1997-12-11
US08/989,249 1997-12-11

Publications (1)

Publication Number Publication Date
WO1999030131A1 true WO1999030131A1 (fr) 1999-06-17

Family

ID=25534909

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/007079 WO1999030131A1 (fr) 1997-12-11 1998-04-10 Test d'immunocapture fluorescent en une etape

Country Status (2)

Country Link
EP (1) EP1046027A1 (fr)
WO (1) WO1999030131A1 (fr)

Cited By (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004021004A1 (fr) * 2002-08-27 2004-03-11 Kimberly-Clark Worldwide, Inc. Dosages a base de membrane utilisant la fluorescence en temps differe
EP1620728A2 (fr) * 2003-05-02 2006-02-01 Access Bio, Inc. Systeme de dosage chromatographique
WO2006036247A1 (fr) * 2004-09-28 2006-04-06 Kimberly-Clark Worldwide, Inc. Detection d'infections a levures par dosage a ecoulement lateral
WO2006119203A2 (fr) * 2005-04-29 2006-11-09 Beckman Coulter Dosage immunologique a ecoulement lateral par fluorescence
EP1737985A2 (fr) * 2004-04-07 2007-01-03 Access Bio, Inc. Systeme de detection d'acides nucleiques
WO2008080031A1 (fr) * 2006-12-21 2008-07-03 Silver Lake Research Corporation Bandes pour test chromatographique d'un ou plusieurs analytes
CN100430726C (zh) * 1999-10-25 2008-11-05 松下电器产业株式会社 免疫色谱试验片及色谱分析方法
US7632653B2 (en) * 2002-08-27 2009-12-15 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices that utilize time-resolved fluorescence
US7651841B2 (en) 2001-12-24 2010-01-26 Kimberly-Clark Worldwide, Inc. Polyelectrolytic internal calibration system of a flow-through assay
US7662643B2 (en) 2002-12-19 2010-02-16 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US7695979B2 (en) 2002-05-03 2010-04-13 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic devices
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7781172B2 (en) 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US7829328B2 (en) 2003-04-03 2010-11-09 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7964340B2 (en) 2004-06-30 2011-06-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
US8110349B2 (en) 2002-05-03 2012-02-07 Kimberly-Clark Worldwide, Inc. Method for producing biomolecule diagnostic devices
US8137985B2 (en) 2001-12-24 2012-03-20 Kimberly-Clark Worldwide, Inc. Polyelectrolytic internal calibration system of a flow-through assay

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258001A (en) * 1978-12-27 1981-03-24 Eastman Kodak Company Element, structure and method for the analysis or transport of liquids
WO1988008534A1 (fr) * 1987-04-27 1988-11-03 Unilever Plc Immuno-analyses et dispositifs pour les realiser
US4812414A (en) * 1987-09-18 1989-03-14 Eastman Kodak Company Immunoreactive reagent particles having tracer, receptor molecules and protein of pI less than 6
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4258001A (en) * 1978-12-27 1981-03-24 Eastman Kodak Company Element, structure and method for the analysis or transport of liquids
WO1988008534A1 (fr) * 1987-04-27 1988-11-03 Unilever Plc Immuno-analyses et dispositifs pour les realiser
US4812414A (en) * 1987-09-18 1989-03-14 Eastman Kodak Company Immunoreactive reagent particles having tracer, receptor molecules and protein of pI less than 6
US5141850A (en) * 1990-02-07 1992-08-25 Hygeia Sciences, Inc. Porous strip form assay device method

Cited By (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100430726C (zh) * 1999-10-25 2008-11-05 松下电器产业株式会社 免疫色谱试验片及色谱分析方法
US8137985B2 (en) 2001-12-24 2012-03-20 Kimberly-Clark Worldwide, Inc. Polyelectrolytic internal calibration system of a flow-through assay
US7651841B2 (en) 2001-12-24 2010-01-26 Kimberly-Clark Worldwide, Inc. Polyelectrolytic internal calibration system of a flow-through assay
US7695979B2 (en) 2002-05-03 2010-04-13 Kimberly-Clark Worldwide, Inc. Biomolecule diagnostic devices
US8110349B2 (en) 2002-05-03 2012-02-07 Kimberly-Clark Worldwide, Inc. Method for producing biomolecule diagnostic devices
WO2004021004A1 (fr) * 2002-08-27 2004-03-11 Kimberly-Clark Worldwide, Inc. Dosages a base de membrane utilisant la fluorescence en temps differe
US7670786B2 (en) 2002-08-27 2010-03-02 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices
US7632653B2 (en) * 2002-08-27 2009-12-15 Kimberly-Clark Worldwide, Inc. Membrane-based assay devices that utilize time-resolved fluorescence
US7662643B2 (en) 2002-12-19 2010-02-16 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in membrane-based assay devices
US7851209B2 (en) 2003-04-03 2010-12-14 Kimberly-Clark Worldwide, Inc. Reduction of the hook effect in assay devices
US7829328B2 (en) 2003-04-03 2010-11-09 Kimberly-Clark Worldwide, Inc. Assay devices that utilize hollow particles
US8034397B2 (en) 2003-04-03 2011-10-11 Kimberly-Clark Worldwide, Inc. Methods of making assay devices utilizing hollow particles
CN104076143A (zh) * 2003-05-02 2014-10-01 安克塞斯生物公司 层析分析系统
EP2026072A1 (fr) * 2003-05-02 2009-02-18 Access Bio, Inc. Système d'analyse chromatographique
US9594078B2 (en) * 2003-05-02 2017-03-14 Access Bio, Inc. Chromatographic assay system
EP1620728A4 (fr) * 2003-05-02 2006-07-05 Access Bio Inc Systeme de dosage chromatographique
CN104076143B (zh) * 2003-05-02 2017-06-13 安克塞斯生物公司 层析分析系统
EP1620728A2 (fr) * 2003-05-02 2006-02-01 Access Bio, Inc. Systeme de dosage chromatographique
US7713748B2 (en) 2003-11-21 2010-05-11 Kimberly-Clark Worldwide, Inc. Method of reducing the sensitivity of assay devices
US7781172B2 (en) 2003-11-21 2010-08-24 Kimberly-Clark Worldwide, Inc. Method for extending the dynamic detection range of assay devices
US7943395B2 (en) 2003-11-21 2011-05-17 Kimberly-Clark Worldwide, Inc. Extension of the dynamic detection range of assay devices
US7943089B2 (en) 2003-12-19 2011-05-17 Kimberly-Clark Worldwide, Inc. Laminated assay devices
EP1737985A4 (fr) * 2004-04-07 2010-07-07 Access Bio Inc Systeme de detection d'acides nucleiques
EP1737985A2 (fr) * 2004-04-07 2007-01-03 Access Bio, Inc. Systeme de detection d'acides nucleiques
US7964340B2 (en) 2004-06-30 2011-06-21 Kimberly-Clark Worldwide, Inc. One-step enzymatic and amine detection technique
WO2006036247A1 (fr) * 2004-09-28 2006-04-06 Kimberly-Clark Worldwide, Inc. Detection d'infections a levures par dosage a ecoulement lateral
WO2006119203A3 (fr) * 2005-04-29 2007-07-05 Beckman Coulter Dosage immunologique a ecoulement lateral par fluorescence
WO2006119203A2 (fr) * 2005-04-29 2006-11-09 Beckman Coulter Dosage immunologique a ecoulement lateral par fluorescence
US7919331B2 (en) 2006-12-21 2011-04-05 Silver Lake Research Corporation Chromatographic test strips for one or more analytes
WO2008080031A1 (fr) * 2006-12-21 2008-07-03 Silver Lake Research Corporation Bandes pour test chromatographique d'un ou plusieurs analytes

Also Published As

Publication number Publication date
EP1046027A1 (fr) 2000-10-25

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