WO1999018202A3 - HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS - Google Patents
HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS Download PDFInfo
- Publication number
- WO1999018202A3 WO1999018202A3 PCT/JP1998/004474 JP9804474W WO9918202A3 WO 1999018202 A3 WO1999018202 A3 WO 1999018202A3 JP 9804474 W JP9804474 W JP 9804474W WO 9918202 A3 WO9918202 A3 WO 9918202A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- proteins
- cdnas
- cells
- utilized
- transmembrane domains
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Toxicology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
Abstract
The invention provides human proteins having transmembrane domains and cDNAs coding for these proteins as well as eucaryotic cells expressing said cDNAs. All of the proteins exist in the cell membrane, so that they are considered to be proteins controlling the proliferation and the differentiation of the cells. Accordingly, the proteins can be employed as pharmaceuticals such as carcinostatic agents relating to the control of the proliferation and the differentiation of the cells or as antigens for preparing antibodies against said proteins. The cDNAs can be utilized as probes for the gene diagnosis and gene sources for the gene therapy. Furthermore, the cDNAs can be utilized for large-scale expression of said proteins. Cells, wherein these membrane protein genes are introduced and membrane proteins are expressed in large amounts, can be utilized for detection of the corresponding ligands, screening of novel low-molecular pharmaceuticals, and so on.
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU92831/98A AU9283198A (en) | 1997-10-08 | 1998-10-05 | Human proteins having transmembrane domains and cdnas encoding these prot eins |
| CA002308120A CA2308120A1 (en) | 1997-10-08 | 1998-10-05 | Human proteins having transmembrane domains and cdnas encoding these proteins |
| EP98945602A EP1021531A2 (en) | 1997-10-08 | 1998-10-05 | HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS |
| JP2000515000A JP2001519153A (en) | 1998-10-05 | 1998-10-05 | Human protein having transmembrane domain and DNA encoding the same |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP27626997 | 1997-10-08 | ||
| JP9/276269 | 1997-10-08 |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| US09529100 A-371-Of-International | 2000-08-21 | ||
| US10/616,942 Continuation US20040048339A1 (en) | 1997-10-08 | 2003-07-11 | Human proteins having transmembrane domains and cDNAs encoding these proteins |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO1999018202A2 WO1999018202A2 (en) | 1999-04-15 |
| WO1999018202A3 true WO1999018202A3 (en) | 1999-08-05 |
Family
ID=17567095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/JP1998/004474 WO1999018202A2 (en) | 1997-10-08 | 1998-10-05 | HUMAN PROTEINS HAVING TRANSMEMBRANE DOMAINS AND cDNAs ENCODING THESE PROTEINS |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1021531A2 (en) |
| AU (1) | AU9283198A (en) |
| CA (1) | CA2308120A1 (en) |
| WO (1) | WO1999018202A2 (en) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2001023553A2 (en) * | 1999-09-29 | 2001-04-05 | Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts | Metastasis-associated antigen c4.4a |
| GB0004576D0 (en) * | 2000-02-25 | 2000-04-19 | Oxford Glycosciences Uk Ltd | Proteins |
-
1998
- 1998-10-05 EP EP98945602A patent/EP1021531A2/en not_active Withdrawn
- 1998-10-05 CA CA002308120A patent/CA2308120A1/en not_active Abandoned
- 1998-10-05 AU AU92831/98A patent/AU9283198A/en not_active Abandoned
- 1998-10-05 WO PCT/JP1998/004474 patent/WO1999018202A2/en not_active Application Discontinuation
Non-Patent Citations (8)
| Title |
|---|
| FENG Y ET AL: "HIV-1 ENTER COFACTOR: FUNCTIONAL CDNA CLONING OF A SEVEN-TRANSMEMBRANE G PROTEIN-COUPLED RECEPTOR", SCIENCE, vol. 272, 10 May 1996 (1996-05-10), pages 872 - 877, XP002031517 * |
| HAJNAL A ET AL: "SUBTRACTION CLONING OF H-REV107, A GENE SPECIFICALLY EXPRESSED IN H-RAS RESISTANT FIBROBLASTS", ONCOGENE, vol. 9, February 1994 (1994-02-01), pages 479 - 490, XP002065314 * |
| HILLIER L ET AL: "Homo sapiens cDNA clone 3' similar to TR:G433963 P18H-REV107" EMBL Database entry HS1269935 Accession number AA478132; 23 Jun 1997 * |
| HILLIER L ET AL: "Homo sapiens cDNA clone 3' similar to TR:G433963 P18H-REV107" EMBL Database entry HS1291066 Accession number AA496125; 03 Jul 1997 * |
| HILLIER L ET AL: "Homo sapiens cDNA clone 5' similar to PIR:S42794 p18H-rev 107 protein" EMBL Database entry HS961329 Accession number W04961; 08 May 1996 * |
| HILLIER L ET AL: "Homo sapiens cDNA clone 5' similar to SP:S42794 P18H-REV 107 protein" EMBL Database entry HS94227 Accession number T53942; 28 Feb 1995 * |
| HOLLOWAY M P ET AL: "A HYDROPHOBIC DOMAIN OF CA2+-MODULATING CYCLOPHILIN LIGAND MODULATES CALCIUM INFLUX SIGNALING IN T LYMPHOCYTES", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 271, no. 15, 12 April 1996 (1996-04-12), pages 8549 - 8552, XP002058790 * |
| KYTE J ET AL: "A SIMPLE METHOD FOR DISPLAYING THE HYDROPATHIC CHARACTER OF A PROTEIN", JOURNAL OF MOLECULAR BIOLOGY, vol. 157, no. 1, 5 May 1982 (1982-05-05), pages 105 - 132, XP000609692 * |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1021531A2 (en) | 2000-07-26 |
| WO1999018202A2 (en) | 1999-04-15 |
| CA2308120A1 (en) | 1999-04-15 |
| AU9283198A (en) | 1999-04-27 |
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