WO1999002554A3 - Human herpesvirus-7 diagnostic and immunologic reagents and use thereof - Google Patents

Human herpesvirus-7 diagnostic and immunologic reagents and use thereof Download PDF

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Publication number
WO1999002554A3
WO1999002554A3 PCT/US1998/014372 US9814372W WO9902554A3 WO 1999002554 A3 WO1999002554 A3 WO 1999002554A3 US 9814372 W US9814372 W US 9814372W WO 9902554 A3 WO9902554 A3 WO 9902554A3
Authority
WO
WIPO (PCT)
Prior art keywords
human herpesvirus
diagnostic
immunologic reagents
reagents
immunologic
Prior art date
Application number
PCT/US1998/014372
Other languages
French (fr)
Other versions
WO1999002554A2 (en
Inventor
Paola Secchiero
Gabriella Campadelli-Fiume
Original Assignee
Univ Maryland Biotech Inst
Univ Bologna
Paola Secchiero
Campadelli Fiume Gabriella
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Maryland Biotech Inst, Univ Bologna, Paola Secchiero, Campadelli Fiume Gabriella filed Critical Univ Maryland Biotech Inst
Priority to EP98935607A priority Critical patent/EP1005543A2/en
Priority to AU84816/98A priority patent/AU8481698A/en
Publication of WO1999002554A2 publication Critical patent/WO1999002554A2/en
Publication of WO1999002554A3 publication Critical patent/WO1999002554A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
    • C12N2710/00011—Details
    • C12N2710/16011—Herpesviridae
    • C12N2710/16511—Roseolovirus, e.g. human herpesvirus 6, 7
    • C12N2710/16522—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The human herpesvirus-7 gene U14 is provided as encoding the major determinant of immunoresponse to HHV-7 infection, i.e., protein pp85. The invention provides specific reagents for serological detection, diagnosis, immunization, and for studies of pathogenesis of human herpesvirus-7.
PCT/US1998/014372 1997-07-10 1998-07-10 Human herpesvirus-7 diagnostic and immunologic reagents and use thereof WO1999002554A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP98935607A EP1005543A2 (en) 1997-07-10 1998-07-10 Human herpesvirus - 7 diagnostic and immunologic reagents and uses thereof
AU84816/98A AU8481698A (en) 1997-07-10 1998-07-10 Human herpesvirus-7 diagnostic and immunologic reagents and methods therefor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89167297A 1997-07-10 1997-07-10
US08/891,672 1997-07-10

Publications (2)

Publication Number Publication Date
WO1999002554A2 WO1999002554A2 (en) 1999-01-21
WO1999002554A3 true WO1999002554A3 (en) 1999-03-25

Family

ID=25398630

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1998/014372 WO1999002554A2 (en) 1997-07-10 1998-07-10 Human herpesvirus-7 diagnostic and immunologic reagents and use thereof

Country Status (3)

Country Link
EP (1) EP1005543A2 (en)
AU (1) AU8481698A (en)
WO (1) WO1999002554A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2818279B1 (en) * 2000-12-15 2005-02-25 Univ Paris Curie GLYCOPROTEIN B PEPTIDE OF HUMAN HERPESVIRUS 7 USEABLE IN PARTICULAR IN AN ELISA SEROLOGICAL TEST

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992001816A1 (en) * 1990-07-19 1992-02-06 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Human herpesvirus-7
WO1994010344A1 (en) * 1992-11-02 1994-05-11 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Diagnostic reagents and their use in the detection of human herpesvirus 7

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992001816A1 (en) * 1990-07-19 1992-02-06 The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce Human herpesvirus-7
US5230997A (en) * 1990-07-19 1993-07-27 The United States Of America As Represented By The Department Of Health And Human Services Methods of detecting the presence of human herpesvirus-7 infection
WO1994010344A1 (en) * 1992-11-02 1994-05-11 The Government Of The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Diagnostic reagents and their use in the detection of human herpesvirus 7

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
KEMPF W. ET AL.: "Persistence of human herpesvirus 7 in normal tissues by expression of a structural antigen", JOURNAL OF INFECTIOUS DISEASES, vol. 178, no. 3, - September 1998 (1998-09-01), pages 841 - 845, XP002088462 *
NICHOLAS J.: "Herpesvirus-7 (HHV-7) JI. Complete genome. Gene U14", EMBL DATABASE, 1 November 1996 (1996-11-01), HEIDELBERG, DE, XP002088454 *
STEFAN A. ET AL.: "The 85-kilodalton phosphoprotein (pp85) of human herpesvirus 7 is encoded by open reading frame U14 and localizes to a tegument substructure in virion particles", JOURNAL OF VIROLOGY, vol. 71, no. 8, 1997, BALTIMORE, US, pages 5758 - 5763, XP002088461 *

Also Published As

Publication number Publication date
AU8481698A (en) 1999-02-08
EP1005543A2 (en) 2000-06-07
WO1999002554A2 (en) 1999-01-21

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