WO1998056810A3 - Proteine humaine lus-i, sa production et son utilisation - Google Patents

Proteine humaine lus-i, sa production et son utilisation Download PDF

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Publication number
WO1998056810A3
WO1998056810A3 PCT/EP1998/003460 EP9803460W WO9856810A3 WO 1998056810 A3 WO1998056810 A3 WO 1998056810A3 EP 9803460 W EP9803460 W EP 9803460W WO 9856810 A3 WO9856810 A3 WO 9856810A3
Authority
WO
WIPO (PCT)
Prior art keywords
cys
thr
ser
ala
glu
Prior art date
Application number
PCT/EP1998/003460
Other languages
German (de)
English (en)
Other versions
WO1998056810A2 (fr
Inventor
Wolf-Georg Forssmann
Gabriele Heine
Knut Adermann
Peter Schulz-Knappe
Michael Nehls
Markus Meyer
Klaus Bensch
Original Assignee
Forssmann Wolf Georg
Gabriele Heine
Knut Adermann
Schulz Knappe Peter
Michael Nehls
Markus Meyer
Klaus Bensch
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE1997149073 external-priority patent/DE19749073C1/de
Application filed by Forssmann Wolf Georg, Gabriele Heine, Knut Adermann, Schulz Knappe Peter, Michael Nehls, Markus Meyer, Klaus Bensch filed Critical Forssmann Wolf Georg
Priority to AU85366/98A priority Critical patent/AU8536698A/en
Publication of WO1998056810A2 publication Critical patent/WO1998056810A2/fr
Publication of WO1998056810A3 publication Critical patent/WO1998056810A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4702—Regulators; Modulating activity
    • C07K14/4703—Inhibitors; Suppressors
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

L'invention concerne une protéine présentant la séquence d'acides aminés de SEQ ID N° 1: NH2-Leu-Lys-Cys-Tyr-Thr- Cys-Lys-Glu-Pro-Met- Thr-Ser-Ala-Ser-Cys-Arg- Thr-Ile-Thr-Arg- Cys-Lys-Pro-Glu-Asp-Thr- Ala-Cys-Met-Thr-Thr-Leu- Val-Thr-Val-Glu-Ala-Glu- Tyr-Pro-Phe- Asn-Gln-Ser-Pro- Val-Val-Thr-Arg- Ser-Cys-Ser-Ser- Ser-Cys-Val-Ala-Thr- Asp-Pro-Asp-Ser- Ile-Gly-Ala-Ala- His-Leu-Ile-Phe- Cys-Cys-Phe-Arg- Asp-Leu-Cys-Asn- Ser-Glu-Leu-COOH (LUS-I). Elle concerne également ses dérivés cycliques, glycosylés, phosphorylés, acétylés, amidés et/ou contenant des liaisons de chaînes latérales, ainsi que des fragments présentant l'activité biologique de LUS-I.
PCT/EP1998/003460 1997-06-09 1998-06-09 Proteine humaine lus-i, sa production et son utilisation WO1998056810A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU85366/98A AU8536698A (en) 1997-06-09 1998-06-09 Lus-1 human protein, its production and use

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19724301 1997-06-09
DE19724301.0 1997-06-09
DE19749073.5 1997-11-06
DE1997149073 DE19749073C1 (de) 1997-11-06 1997-11-06 Humanes ANUP (humanes Anti-Neoplastisches-Urin-Peptid), seine Herstellung und Verwendung

Publications (2)

Publication Number Publication Date
WO1998056810A2 WO1998056810A2 (fr) 1998-12-17
WO1998056810A3 true WO1998056810A3 (fr) 1999-03-11

Family

ID=26037290

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/003460 WO1998056810A2 (fr) 1997-06-09 1998-06-09 Proteine humaine lus-i, sa production et son utilisation

Country Status (2)

Country Link
AU (1) AU8536698A (fr)
WO (1) WO1998056810A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE602004031003D1 (de) * 2003-04-16 2011-02-24 Merck Serono Sa Verwendung von slurp-1 zur behandlung von krankheiten, die durch störungen der acetylcholinerezeptoren ausgelöst werden

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5298604A (en) * 1992-07-27 1994-03-29 Sloane Nathan H Parital primary amino acid sequence of the antineoplastic protein (ANUP); a cytokine present in granulocytes
WO1994014959A1 (fr) * 1992-12-22 1994-07-07 Applied Research Systems Ars Holding N.V. Nouvelle proteine d'origine urinaire appelee composant b

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5298604A (en) * 1992-07-27 1994-03-29 Sloane Nathan H Parital primary amino acid sequence of the antineoplastic protein (ANUP); a cytokine present in granulocytes
WO1994014959A1 (fr) * 1992-12-22 1994-07-07 Applied Research Systems Ars Holding N.V. Nouvelle proteine d'origine urinaire appelee composant b

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
MASTRANGELI R.: "H. sapiens ARS gene, component B, ARS", EMBL DATABASE, 11 September 1996 (1996-09-11), HEIDELBERG, DE, XP002087799 *
SLOANE N.H. ET AL.: "Studies on an antineoplastic fraction from human urine characterization of the major protein in this fraction", BIOCHEMICAL JOURNAL, vol. 234, no. 2, 1986, pages 355 - 362, XP002087807 *

Also Published As

Publication number Publication date
AU8536698A (en) 1998-12-30
WO1998056810A2 (fr) 1998-12-17

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