WO1998001570A3 - Mutated antibody-dependent infection enhancing domains of hiv - Google Patents
Mutated antibody-dependent infection enhancing domains of hiv Download PDFInfo
- Publication number
- WO1998001570A3 WO1998001570A3 PCT/US1997/011667 US9711667W WO9801570A3 WO 1998001570 A3 WO1998001570 A3 WO 1998001570A3 US 9711667 W US9711667 W US 9711667W WO 9801570 A3 WO9801570 A3 WO 9801570A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hiv
- antibody
- mutated antibody
- dependent
- dependent infection
- Prior art date
Links
- 230000002708 enhancing effect Effects 0.000 title abstract 4
- 230000001419 dependent effect Effects 0.000 title abstract 3
- 208000015181 infectious disease Diseases 0.000 title 1
- 241000725303 Human immunodeficiency virus Species 0.000 abstract 3
- 230000004075 alteration Effects 0.000 abstract 3
- 101800001690 Transmembrane protein gp41 Proteins 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 2
- 229940033330 HIV vaccine Drugs 0.000 abstract 1
- 241000700605 Viruses Species 0.000 abstract 1
- 230000006698 induction Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/15011—Lentivirus, not HIV, e.g. FIV, SIV
- C12N2740/15022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/16011—Human Immunodeficiency Virus, HIV
- C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
- C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU36501/97A AU3650197A (en) | 1996-07-05 | 1997-07-02 | Mutated antibody-dependent infection enhancing domains of hiv |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US2166896P | 1996-07-05 | 1996-07-05 | |
US60/021,668 | 1996-07-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998001570A2 WO1998001570A2 (en) | 1998-01-15 |
WO1998001570A3 true WO1998001570A3 (en) | 1998-02-26 |
Family
ID=21805497
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/011667 WO1998001570A2 (en) | 1996-07-05 | 1997-07-02 | Mutated antibody-dependent infection enhancing domains of hiv |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU3650197A (en) |
WO (1) | WO1998001570A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2369119A1 (en) | 1999-03-29 | 2000-05-25 | Statens Serum Institut | Nucleotide construct with optimised codons for an hiv genetic vaccine based on a primary, early hiv isolate and synthetic envelope |
WO2013026452A1 (en) * | 2011-08-23 | 2013-02-28 | Skau Aps | Method for removing immunosuppresive properties of hiv envelope glycoproteins |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5019510A (en) * | 1987-10-28 | 1991-05-28 | Institut Pasteur | Isolation, molecular cloning and sequencing of an HIV-1 isolate from a Gabonese donor |
WO1995007987A2 (en) * | 1993-09-16 | 1995-03-23 | Solvay S.A. | Novel proteins/polypeptides and cotransfection plasmids and live recombinant carriers therefor |
WO1997014442A1 (en) * | 1995-10-18 | 1997-04-24 | Merlin Technologies, Inc. | Hormone immunomodulated induction of mucosal immune responses |
-
1997
- 1997-07-02 AU AU36501/97A patent/AU3650197A/en not_active Abandoned
- 1997-07-02 WO PCT/US1997/011667 patent/WO1998001570A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5019510A (en) * | 1987-10-28 | 1991-05-28 | Institut Pasteur | Isolation, molecular cloning and sequencing of an HIV-1 isolate from a Gabonese donor |
WO1995007987A2 (en) * | 1993-09-16 | 1995-03-23 | Solvay S.A. | Novel proteins/polypeptides and cotransfection plasmids and live recombinant carriers therefor |
WO1997014442A1 (en) * | 1995-10-18 | 1997-04-24 | Merlin Technologies, Inc. | Hormone immunomodulated induction of mucosal immune responses |
Non-Patent Citations (6)
Title |
---|
J.R MASCOLA ET AL.: "Summary report: workshop on the potential risks of antibody-dependent enhancement in human HIV vaccine trials", AIDS RESEARCH AND HUMAN RETROVIRUSES, vol. 9, no. 12, December 1993 (1993-12-01), NEW YORK US, pages 1175 - 1184, XP002049761 * |
MITCHELL W M ET AL: "Induction of mucosal anti-HIV antibodies by facilitated transfection of airway epithelium with lipospermine/DNA complexes", IMMUNOTECHNOLOGY, vol. 1, no. 3, December 1995 (1995-12-01), AMSTERDAM NL, pages 211-219, XP004052723 * |
P. AUEWARAKUL ET AL.: "Analysis of neutralizing and enhancing antibodies to human immunodeficiency virus type 1 primary isolates in plasma of individuals infected with env Genetic subtype B and E viruses in Thailand", VIRAL IMMUNOLOGY, vol. 9, no. 3, March 1996 (1996-03-01), US, pages 175 - 185, XP002049758 * |
S.B. JIANG ET AL: "Enhancement of human immunodeficiency virus type 1 infection by antisera to peptides from the envelope glycoproteins gp140/gp41", THE JOURNAL OF EXPERIMENTAL MEDICINE, vol. 174, no. 6, 1 December 1991 (1991-12-01), NEW YORK US, pages 1557 - 1563, XP002049759 * |
S.C. KLIKS ET AL.: "V3 variability can influence the ability of an antibody to neutralize or enhance infection by diverse strains of human immunodeficiency virus type 1", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA., vol. 90, December 1993 (1993-12-01), WASHINGTON US, pages 11518 - 11522, XP002049757 * |
W.E. ROBINSON JR ET AL.: "Antibodies to the primary immunodominant domain of human immunodeficiency virus type 1 (HIV-1) glycoprotein gp41 enhance HIV-1 infection in vitro", JOURNAL OF VIROLOGY., vol. 64, no. 11, November 1990 (1990-11-01), BALTIMORE US, pages 5301 - 5305, XP002049760 * |
Also Published As
Publication number | Publication date |
---|---|
AU3650197A (en) | 1998-02-02 |
WO1998001570A2 (en) | 1998-01-15 |
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