WO1997012553A1 - Lumpectomy facilitating apparatus and methods related thereto - Google Patents
Lumpectomy facilitating apparatus and methods related thereto Download PDFInfo
- Publication number
- WO1997012553A1 WO1997012553A1 PCT/US1996/015757 US9615757W WO9712553A1 WO 1997012553 A1 WO1997012553 A1 WO 1997012553A1 US 9615757 W US9615757 W US 9615757W WO 9712553 A1 WO9712553 A1 WO 9712553A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- margin
- recited
- needle
- mass
- cage
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B90/00—Instruments, implements or accessories specially adapted for surgery or diagnosis and not covered by any of the groups A61B1/00 - A61B50/00, e.g. for luxation treatment or for protecting wound edges
- A61B90/39—Markers, e.g. radio-opaque or breast lesions markers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
- A61B17/221—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions
- A61B2017/2215—Gripping devices in the form of loops or baskets for gripping calculi or similar types of obstructions having an open distal end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/30—Surgical pincettes without pivotal connections
- A61B2017/303—Surgical pincettes without pivotal connections with four or more legs
Definitions
- the present invention relates to an apparatus for marking a tumor mass so that a surgeon can locate the tumor mass during a lumpectomy operation, and more particularly to an apparatus which can be used to guide the surgeon during the removal of the tumor mass so that a single fragment of tissue with a tumor mass centrally located therein can be removed.
- the devices merely indicate the location of the tumor mass and since the boundaries of the tumor mass are often difficult to determine, it is common for the tumor mass to be located at a margin of the specimen which is removed. As such, cancerous tissue is often left within the breast after the lumpectomy specimen has been removed.
- the surgeon must then remove a second piece of tissue in an attempt to remove any remaining cancerous tissue.
- the second piece of tissue is taken from the correct location or that all of the cancerous tissue has been removed.
- the lumpectomy specimen may be in fragments.
- It is another object of the invention to provide an apparatus comprising a housing needle which includes one or more margin wires which can be deployed to form a cage around a tumor mass so as to provide a guide for the removal of the tumor with an approximately uniform margin of tumor-free tissue.
- Figure 1 is a cross-sectional view of an apparatus in accordance with the present invention with undeployed margin wires
- Figure 2 is a cross-sectional view of a first embodiment of the apparatus of Figure 1 with the margin wires deployed;
- Figure 3 is a cross-sectional view of a housing needle with the margin wires positioned within the wall of the housing needle;
- Figure 4 is a perspective view of a second embodiment of the present invention with the margin wires deployed;
- Figure 5 illustrates a curved segment through which the margin wires are deployed in accordance with a second embodiment of the invention
- Figure 6A is a side view of a deployed cage
- Figure 6B is a cross-sectional view of the housing needle after the deployment of the margin wires and decoupling of the housing needle from the wire cage.
- the present invention generally provides an apparatus which includes one or more margin wires housed within a needle.
- the wires are deployed to form a cage a predetermined distance from and around a tumor mass so as to define a tumor free area around the tumor mass.
- the surgeon uses the cage as a guide so that the complete tumor mass surrounded by an approximately uniform tumor free margin of tissue can be removed.
- a method of defining an area around a tumor mass and a method of removing a tumor mass with an approximately uniform predetermined tumor free margin of tissue are provided.
- a proper lumpectomy specimen removed at surgery should, in most instances, be a roughly spherically shaped single fragment of tissue which contains the tumor mass centrally located within the tissue fragment with, preferably, approximately l cm or more of surrounding tumor-free tissue.
- a proper lumpectomy specimen can be marked and/or removed.
- a housing needle is inserted into a breast so that the end of the needle is positioned approximately 0.7 to 1.3 cm, and preferably, approximately 1 cm, from the tumor mass.
- the end of the needle can be positioned on one side of the tumor or can be inserted through the tumor, depending on the configuration of and method of deploying the wires.
- the wires are then deployed from the housing needle through the tissue in a manner so as to form an arc or circle around the tumor mass and thereby define an tumor free area around the tumor mass.
- the margin wire(s) can partially or fully encompass the tumor mass.
- Figure 1 is intended to provide a non-limiting example of an apparatus according to the invention.
- Figure 1 shows a housing needle 20 which is inserted into the patient's breast.
- the needle 20 contains margin wires 10 which are attached to one side of a plunger plate 40.
- a plunger plate advancing rod 30 is attached to a second side of the plunger plate 40 opposite to the margin wires 10. The advancing rod 30 is used to move the plunger plate 40 and thereby move the margin wires 10.
- a hub plate 50 is located at the tip of the needle 54 which is inserted into the patient.
- the hub plate 50 can include channels 52 to guide the margin wires 10 out of the needle 20.
- the channels 52 can be straight or can be curved, as will be discussed infra .
- the plunger plate 40 can include a clasping device 42 to lock the plunger plate to the hub plate 50 once the plunger plate has been completely deployed.
- the margin wires 10 it is also possible for the margin wires 10 to be placed within the wall 100 of a housing needle 20 and then deployed. It is contemplated that other methods for housing the wires within the needle and for deploying the margin wires 10 can be used. Referring now to Figure 2 , the embodiment of
- Figure 1 is shown with the margin wires 10 after deployment.
- the end of the needle 54 is positioned to one side of the tumor mass 80 and the wires 10 move forward in an arc-like manner so as to form a cage or basket 110 around the tumor mass 80.
- the advancing rod 30 within the needle 20 drives the margin wires 10 through the channels 52 in the hub plate 50 which is located at the tip of the needle 54.
- the margin wires 10 have memory characteristics which are activated by any of the known methods, such as stress or thermal activation.
- Wires with memory characteristics are known in the art and include, for example, arch wires, such as NITINOL® wire (3M Unitek Corporation) .
- the memory characteristics cause the wires to follow a semicircular path through the tissue surrounding the tumor.
- a wire with memory characteristics indicates that a wire can be maintained in a predetermined orientation until the wire is activated.
- the wire "remembers" a prior orientation.
- One example is a wire which has been bent into a particular shape and then is straightened. The straight wire can then be stored and later activated when the bent wire is desired.
- the wires meet at a coterminus 70, thereby forming a cage or a basket 110 around the tumor mass 80 at a predetermined distance away from the tumor mass.
- the cage 110 can partially or fully encompass the tumor mass 80. It is preferred that the end of the needle is positioned approximately 0.7 to 1.3 cm, and preferably, approximately 1 cm, away from the edges of a tumor mass. The placement of the needle at this distance and the use of wire with memory characteristics or the deployment of wire through a curved channel or segment will produce a cage which is approximately 0.7 to 1.3 cm away from the tumor at all positions.
- margin wires 10 are used to form the cage or basket 110 around the tumor mass 80, however, other numbers of wires can be used.
- the wires can be coded, such as with color, in order to orient the removed lumpectomy specimen with respect to the margin direction (i.e. anterior, posterior, superior, inferior, right and left) .
- the margin wires be tempered or hardened so that the wires can only be cut with special cutters, thereby preventing inadvertent fragmentation of the wires by surgical scissors or scalpels during the lumpectomy operation.
- wires should be chosen which are of a diameter so as not to cause significant damage to the tissue around the tumor mass.
- the margin wires can be made from any well known type of wire which is acceptable for use in medical applications, such as titanium or stainless steel surgical wire. Further, it is contemplated that wires of different shapes can be used. However, it is preferred to use rounded or square wires.
- FIG. 4 A second embodiment of the invention with deployed wires is shown in Figure 4.
- the needle 20 is passed through the tumor mass 80 and the margin wires 10 move back toward the needle 20 in a reverse arc-like manner so as to form a basket 110 around the tumor mass.
- the margin wires 10 are moved through the needle 20.
- the margin wires are passed through a curved channel or segment, for example 92 in Figure 5.
- the curved segment 92 causes the wire 10 to bend back towards the needle 20 and thereby form a basket or cage 110 around the tumor mass 80.
- a wire will follow the radius of curvature it last saw i.e., the wire will bend in accordance with the curved portion it most recently was passed through.
- arc length and wire material can be varied to adjust the size of the arc formed by the margin wire. It is also contemplated that other known metal bending techniques can be used to cause the margin wires to follow a predetermined path after the wires 10 are deployed from the housing needle 20.
- the margin wires 10 can be simultaneously or sequentially deployed.
- individual curved channels or segments 92 can be provided for each margin wire 10 to pass through during deployment.
- a single curved channel or segment 92 can be aligned with each margin wire to individually deploy the margin wire 10 in the desired direction.
- the wires form a cage or a basket 110 around the tumor mass 80 at a predetermined distance away from the tumor mass 80.
- the cage or basket 110 is formed from one or more margin wires 10 and can partially or fully surround the tumor mass 80. As discussed above, it is preferred that the margin wires are located approximately 0.7 to 1.3 cm, and most preferably approximately 1 cm, away from the edges of the tumor mass. It is preferred, for safety reasons, that the margin wires 10 are not removable from the plunger plate 40.
- the plunger plate 40 is firmly attached to the hub plate 50 in order to increase the likelihood that the basket 110 will remain as a single intact unit and to reduce the possibility that the wires or other parts of the apparatus will become separated and wander within the tissue after deployment.
- the margin wires 10 can include proximal nodes or other protrusions 12 which become fixed within or just beyond the hub plate 50 upon complete deployment of the margin wires.
- the advancing rod 30 can be retracted and the stabilizing post 60 can be detached from the hub plate 50, as shown in Figure 6B.
- the needle 20 can then be removed from the site of the tumor.
- the wire cage 110 with the attached hub plate 50 and plunger plate 40, as shown in Figure 6A, remains embedded in the tissue.
- the needle can be reinserted and the stabilizing post 60 can be reattached to the deployed cage and the cage can be removed without additional surgery.
- the wire cage 110 can be localized by any of the known methods including the use of a metal sensing device, by finger palpation, by preoperative visual inspection and/or by radiographic examination. A small incision is then made and the tissue is dissected until the hub plate 50 of the cage 110 or the cage itself is exposed. A suture can be attached to the hub plate 50 to apply tension to the hub plate and stabilize the deployed cage 110 within the tissue. The tissue along the margin wires 10 of the cage 110 is then dissected and the cage is removed along with the tumor mass and a margin of tumor free tissue.
- the end of the needle can be of any desired shape, including circular or rectangular and can include beveled edges to facilitate entry of the needle into the tissue.
- the original placement of the needle can be accomplished using existing three-dimensional stereotactic technology or under routine mammographic guidance.
- other standard techniques for localizing tumors can be used for the initial placement of the needle.
- the needle using currently available stereotactic devices, is preferably placed within the breast by the stereotactic unit's computer- driven robotics.
- the tip of the needle is positioned approximately 0.7 to 1.3 cm, and preferably approximately 1 cm, from or beyond the radiologically apparent tumor mass.
- the placement of the needle at this distance and the use of wire with memory characteristics or the deployment of wire through a curved segment will produce a cage which is approximately 0.7 to 1.3 cm away from the tumor at all positions.
- the housing needle may have internal directional grooves or guides to facilitate the proper equidistant spacial placement of the margin wires forming the basket. It is also contemplated that the apparatus of the present invention can be inserted through a biopsy device or in the location of a biopsy device which has been removed from the breast.
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Pathology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Surgical Instruments (AREA)
Abstract
Description
Claims
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU72520/96A AU7252096A (en) | 1995-10-03 | 1996-10-01 | Lumpectomy facilitating apparatus and methods related thereto |
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US471595P | 1995-10-03 | 1995-10-03 | |
US60/004,715 | 1995-10-03 | ||
US1497696P | 1996-04-08 | 1996-04-08 | |
US06/014,976 | 1996-04-08 | ||
US72257696A | 1996-10-01 | 1996-10-01 | |
US08/722,576 | 1996-10-01 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997012553A1 true WO1997012553A1 (en) | 1997-04-10 |
Family
ID=27357697
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1996/015757 WO1997012553A1 (en) | 1995-10-03 | 1996-10-01 | Lumpectomy facilitating apparatus and methods related thereto |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU7252096A (en) |
CA (1) | CA2233967A1 (en) |
WO (1) | WO1997012553A1 (en) |
Cited By (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999053848A1 (en) * | 1998-04-23 | 1999-10-28 | Scimed Life Systems, Inc. | Surgical retrieval basket with the ability to capture and release material |
WO2002039913A1 (en) * | 2000-11-14 | 2002-05-23 | Mario Immacolato Paternuosto | Shape memory device for strangulating pedunculated polyps during endoscopy |
EP1341466A1 (en) * | 1998-05-14 | 2003-09-10 | Calypso Medical, Inc | Systems and methods for stabilizing a targert location within a human body |
WO2005089065A2 (en) | 2004-03-23 | 2005-09-29 | Dune Medical Devices Ltd. | Clean margin assessment tool |
US7904145B2 (en) | 2004-03-23 | 2011-03-08 | Dune Medical Devices Ltd. | Clean margin assessment tool |
US8147423B2 (en) | 2007-03-01 | 2012-04-03 | Dune Medical Devices, Ltd. | Tissue-characterization system and method |
US8195282B2 (en) | 2001-11-19 | 2012-06-05 | Dune Medical Devices Ltd | Method and apparatus for examining tissue for predefined target cells, particularly cancerous cells, and a probe useful in such method and apparatus |
US9072895B2 (en) | 2001-06-08 | 2015-07-07 | Varian Medical Systems, Inc. | Guided radiation therapy system |
US9237860B2 (en) | 2008-06-05 | 2016-01-19 | Varian Medical Systems, Inc. | Motion compensation for medical imaging and associated systems and methods |
US9238151B2 (en) | 2004-07-23 | 2016-01-19 | Varian Medical Systems, Inc. | Dynamic/adaptive treatment planning for radiation therapy |
US9248003B2 (en) | 2002-12-30 | 2016-02-02 | Varian Medical Systems, Inc. | Receiver used in marker localization sensing system and tunable to marker frequency |
US9283053B2 (en) | 2005-09-19 | 2016-03-15 | Varian Medical Systems, Inc. | Apparatus and methods for implanting objects, such as bronchoscopically implanting markers in the lung of patients |
US9586059B2 (en) | 2004-07-23 | 2017-03-07 | Varian Medical Systems, Inc. | User interface for guided radiation therapy |
US9616248B2 (en) | 2002-06-05 | 2017-04-11 | Varian Medical Systems, Inc. | Integrated radiation therapy systems and methods for treating a target in a patient |
US9623208B2 (en) | 2004-01-12 | 2017-04-18 | Varian Medical Systems, Inc. | Instruments with location markers and methods for tracking instruments through anatomical passageways |
US9750425B2 (en) | 2004-03-23 | 2017-09-05 | Dune Medical Devices Ltd. | Graphical user interfaces (GUI), methods and apparatus for data presentation |
US9919165B2 (en) | 2014-05-07 | 2018-03-20 | Varian Medical Systems, Inc. | Systems and methods for fiducial to plan association |
US10043284B2 (en) | 2014-05-07 | 2018-08-07 | Varian Medical Systems, Inc. | Systems and methods for real-time tumor tracking |
US10195464B2 (en) | 2004-06-24 | 2019-02-05 | Varian Medical Systems, Inc. | Systems and methods for treating a lung of a patient using guided radiation therapy or surgery |
US10293135B2 (en) | 2010-10-01 | 2019-05-21 | Varian Medical Systems, Inc. | Delivery catheter for and method of delivering implant, for example, bronchoscopically implanting a marker in a lung |
US10716613B2 (en) | 2012-02-13 | 2020-07-21 | Koninklijke Philips N.V. | Photonic probe apparatus with integrated tissue marking facility |
CN113520573A (en) * | 2021-07-23 | 2021-10-22 | 天津医科大学第二医院 | Necrosis device is kept apart to wicresoft's tumour |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5083570A (en) * | 1990-06-18 | 1992-01-28 | Mosby Richard A | Volumetric localization/biopsy/surgical device |
US5496330A (en) * | 1993-02-19 | 1996-03-05 | Boston Scientific Corporation | Surgical extractor with closely angularly spaced individual filaments |
-
1996
- 1996-10-01 CA CA002233967A patent/CA2233967A1/en not_active Abandoned
- 1996-10-01 WO PCT/US1996/015757 patent/WO1997012553A1/en active Application Filing
- 1996-10-01 AU AU72520/96A patent/AU7252096A/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5083570A (en) * | 1990-06-18 | 1992-01-28 | Mosby Richard A | Volumetric localization/biopsy/surgical device |
US5496330A (en) * | 1993-02-19 | 1996-03-05 | Boston Scientific Corporation | Surgical extractor with closely angularly spaced individual filaments |
Cited By (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999053848A1 (en) * | 1998-04-23 | 1999-10-28 | Scimed Life Systems, Inc. | Surgical retrieval basket with the ability to capture and release material |
EP1341466A1 (en) * | 1998-05-14 | 2003-09-10 | Calypso Medical, Inc | Systems and methods for stabilizing a targert location within a human body |
EP1341466A4 (en) * | 1998-05-14 | 2006-07-05 | Calypso Medical Inc | Systems and methods for stabilizing a targert location within a human body |
WO2002039913A1 (en) * | 2000-11-14 | 2002-05-23 | Mario Immacolato Paternuosto | Shape memory device for strangulating pedunculated polyps during endoscopy |
US9072895B2 (en) | 2001-06-08 | 2015-07-07 | Varian Medical Systems, Inc. | Guided radiation therapy system |
US8195282B2 (en) | 2001-11-19 | 2012-06-05 | Dune Medical Devices Ltd | Method and apparatus for examining tissue for predefined target cells, particularly cancerous cells, and a probe useful in such method and apparatus |
US9226979B2 (en) | 2001-11-19 | 2016-01-05 | Dune Medical Devices Ltd. | Method and apparatus for examining tissue for predefined target cells, particularly cancerous cells, and a probe useful in such method and apparatus |
US9682253B2 (en) | 2002-06-05 | 2017-06-20 | Varian Medical Systems, Inc. | Integrated radiation therapy systems and methods for treating a target in a patient |
US9616248B2 (en) | 2002-06-05 | 2017-04-11 | Varian Medical Systems, Inc. | Integrated radiation therapy systems and methods for treating a target in a patient |
US9248003B2 (en) | 2002-12-30 | 2016-02-02 | Varian Medical Systems, Inc. | Receiver used in marker localization sensing system and tunable to marker frequency |
US9623208B2 (en) | 2004-01-12 | 2017-04-18 | Varian Medical Systems, Inc. | Instruments with location markers and methods for tracking instruments through anatomical passageways |
US7720532B2 (en) | 2004-03-23 | 2010-05-18 | Dune Medical Ltd. | Clean margin assessment tool |
US7904145B2 (en) | 2004-03-23 | 2011-03-08 | Dune Medical Devices Ltd. | Clean margin assessment tool |
WO2005089065A2 (en) | 2004-03-23 | 2005-09-29 | Dune Medical Devices Ltd. | Clean margin assessment tool |
US9750425B2 (en) | 2004-03-23 | 2017-09-05 | Dune Medical Devices Ltd. | Graphical user interfaces (GUI), methods and apparatus for data presentation |
US11179053B2 (en) | 2004-03-23 | 2021-11-23 | Dilon Medical Technologies Ltd. | Graphical user interfaces (GUI), methods and apparatus for data presentation |
US11439847B2 (en) | 2004-06-24 | 2022-09-13 | Varian Medical Systems, Inc. | Systems and methods for treating a lung of a patient using guided radiation therapy or surgery |
US10195464B2 (en) | 2004-06-24 | 2019-02-05 | Varian Medical Systems, Inc. | Systems and methods for treating a lung of a patient using guided radiation therapy or surgery |
US9238151B2 (en) | 2004-07-23 | 2016-01-19 | Varian Medical Systems, Inc. | Dynamic/adaptive treatment planning for radiation therapy |
US9586059B2 (en) | 2004-07-23 | 2017-03-07 | Varian Medical Systems, Inc. | User interface for guided radiation therapy |
US9283053B2 (en) | 2005-09-19 | 2016-03-15 | Varian Medical Systems, Inc. | Apparatus and methods for implanting objects, such as bronchoscopically implanting markers in the lung of patients |
US10653496B2 (en) | 2005-09-19 | 2020-05-19 | Varian Medical Systems, Inc. | Apparatus and methods for implanting objects, such as a bronchoscopically implanting markers in the lung of patients |
US8147423B2 (en) | 2007-03-01 | 2012-04-03 | Dune Medical Devices, Ltd. | Tissue-characterization system and method |
US9237860B2 (en) | 2008-06-05 | 2016-01-19 | Varian Medical Systems, Inc. | Motion compensation for medical imaging and associated systems and methods |
US10293135B2 (en) | 2010-10-01 | 2019-05-21 | Varian Medical Systems, Inc. | Delivery catheter for and method of delivering implant, for example, bronchoscopically implanting a marker in a lung |
US10716613B2 (en) | 2012-02-13 | 2020-07-21 | Koninklijke Philips N.V. | Photonic probe apparatus with integrated tissue marking facility |
US10043284B2 (en) | 2014-05-07 | 2018-08-07 | Varian Medical Systems, Inc. | Systems and methods for real-time tumor tracking |
US9919165B2 (en) | 2014-05-07 | 2018-03-20 | Varian Medical Systems, Inc. | Systems and methods for fiducial to plan association |
CN113520573A (en) * | 2021-07-23 | 2021-10-22 | 天津医科大学第二医院 | Necrosis device is kept apart to wicresoft's tumour |
CN113520573B (en) * | 2021-07-23 | 2022-04-29 | 天津医科大学第二医院 | Necrosis device is kept apart to wicresoft's tumour |
Also Published As
Publication number | Publication date |
---|---|
AU7252096A (en) | 1997-04-28 |
CA2233967A1 (en) | 1997-04-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1997012553A1 (en) | Lumpectomy facilitating apparatus and methods related thereto | |
US6066122A (en) | Needle apparatus and method for marking lesions | |
US6080114A (en) | Method for coaxial breast biopsy | |
EP0385604B1 (en) | Surgical needle and localisation needle assembly | |
US5083570A (en) | Volumetric localization/biopsy/surgical device | |
US5853366A (en) | Marker element for interstitial treatment and localizing device and method using same | |
US5782775A (en) | Apparatus and method for localizing and removing tissue | |
CA2262550C (en) | Apparatus and method for marking tissue | |
US5127916A (en) | Localization needle assembly | |
US6564806B1 (en) | Device for accurately marking tissue | |
US7261712B2 (en) | Electrosurgical lesion location device | |
US5158084A (en) | Modified localization wire for excisional biopsy | |
EP1096875B1 (en) | Biopsy localization device | |
US8277391B2 (en) | Methods and devices for defining and marking tissue | |
US7736292B2 (en) | Brachytherapy apparatus and methods of using same | |
US9259560B2 (en) | Brachytherapy array preparation device | |
KR101580098B1 (en) | Surgical suturing device and tools used therewith | |
US20090000629A1 (en) | Elastically Deformable Marker | |
WO1998001068A9 (en) | Marker element for interstitial treatment and localizing device and method using same | |
JPH11501236A (en) | Device for locating suspected breast lesions and mounting device for said device | |
AU2006311279A1 (en) | Brachytherapy apparatus and methods for using them | |
JP2022169750A (en) | Devices and methods for tissue retraction | |
CN104856742A (en) | Method And Device For Installing An Implant For A Bone Anchored Hearing Aid | |
CN108348288B (en) | Retractable tissue cutting device | |
KR102494673B1 (en) | Apparatus and Method for Cutting and Retrieving Breast Specimen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A1 Designated state(s): AU CA JP MX |
|
AL | Designated countries for regional patents |
Kind code of ref document: A1 Designated state(s): AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
121 | Ep: the epo has been informed by wipo that ep was designated in this application | ||
ENP | Entry into the national phase |
Ref document number: 2233967 Country of ref document: CA Ref document number: 2233967 Country of ref document: CA Kind code of ref document: A |
|
WWE | Wipo information: entry into national phase |
Ref document number: PA/A/1998/002628 Country of ref document: MX |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1996933994 Country of ref document: EP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1996933994 Country of ref document: EP |
|
122 | Ep: pct application non-entry in european phase |