WO1997006437A1 - Diagnostic device - Google Patents
Diagnostic device Download PDFInfo
- Publication number
- WO1997006437A1 WO1997006437A1 PCT/EP1996/003380 EP9603380W WO9706437A1 WO 1997006437 A1 WO1997006437 A1 WO 1997006437A1 EP 9603380 W EP9603380 W EP 9603380W WO 9706437 A1 WO9706437 A1 WO 9706437A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- branch
- sample
- conduit
- liquid
- junction
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502715—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by interfacing components, e.g. fluidic, electrical, optical or mechanical interfaces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/558—Immunoassay; Biospecific binding assay; Materials therefor using diffusion or migration of antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56983—Viruses
- G01N33/56988—HIV or HTLV
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0621—Control of the sequence of chambers filled or emptied
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0645—Electrodes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0654—Lenses; Optical fibres
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0681—Filter
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/069—Absorbents; Gels to retain a fluid
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0809—Geometry, shape and general structure rectangular shaped
- B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0688—Valves, specific forms thereof surface tension valves, capillary stop, capillary break
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/08—Regulating or influencing the flow resistance
- B01L2400/084—Passive control of flow resistance
- B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Biotechnology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Dispersion Chemistry (AREA)
- Virology (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Description
Claims
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU67887/96A AU6788796A (en) | 1995-08-03 | 1996-07-30 | Diagnostic device |
JP9508098A JPH11510601A (en) | 1995-08-03 | 1996-07-30 | Diagnostic device |
EP96928401A EP0843817A1 (en) | 1995-08-03 | 1996-07-30 | Diagnostic device |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95202118 | 1995-08-03 | ||
EP95202118.6 | 1995-08-03 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1997006437A1 true WO1997006437A1 (en) | 1997-02-20 |
Family
ID=8220545
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1996/003380 WO1997006437A1 (en) | 1995-08-03 | 1996-07-30 | Diagnostic device |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0843817A1 (en) |
JP (1) | JPH11510601A (en) |
KR (1) | KR19990036069A (en) |
AU (1) | AU6788796A (en) |
CA (1) | CA2228485A1 (en) |
WO (1) | WO1997006437A1 (en) |
Cited By (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999047255A1 (en) * | 1998-03-17 | 1999-09-23 | Cepheid | Unitary chemical processing device |
WO2001026813A2 (en) * | 1999-10-08 | 2001-04-19 | Micronics, Inc. | Microfluidics without electrically of mechanically operated pumps |
EP1391241A1 (en) * | 1999-04-21 | 2004-02-25 | Clinical Micro Sensors | The use of microfluidic systems in the electrochemical detection of target analytes |
EP1461615A1 (en) * | 2001-12-12 | 2004-09-29 | Proteome Systems Intellectual Property Pty Ltd. | Diagnostic testing process |
WO2006039542A1 (en) * | 2004-09-30 | 2006-04-13 | Quidel Corporation | Analytical devices with primary and secondary flow paths |
US7794656B2 (en) | 2006-01-23 | 2010-09-14 | Quidel Corporation | Device for handling and analysis of a biological sample |
US7871568B2 (en) | 2006-01-23 | 2011-01-18 | Quidel Corporation | Rapid test apparatus |
US8101403B2 (en) | 2006-10-04 | 2012-01-24 | University Of Washington | Method and device for rapid parallel microfluidic molecular affinity assays |
US8216853B2 (en) | 2003-09-10 | 2012-07-10 | Abbott Point Of Care Inc. | Immunoassay device with improved sample closure |
WO2013111026A1 (en) * | 2012-01-24 | 2013-08-01 | Koninklijke Philips N.V. | Analysis cartridge with filter unit |
US9289764B2 (en) | 2010-12-20 | 2016-03-22 | Boehringer Ingelheim Microparts Gmbh | Method for mixing at least one sample solution having at least one reagent, and device |
US9643182B2 (en) | 2010-04-16 | 2017-05-09 | Opko Diagnostics, Llc | Systems and devices for analysis of samples |
US9827564B2 (en) | 2009-02-02 | 2017-11-28 | Opko Diagnostics, Llc | Fluidic systems and methods for analyses |
DE102018207548B3 (en) | 2018-05-16 | 2019-06-19 | Robert Bosch Gmbh | Sensor device with a hydrophobic and / or anti-adhesive protective layer and method for producing such a sensor device |
US10408824B2 (en) | 2007-05-04 | 2019-09-10 | Opko Diagnostics, Llc | Fluidic connectors and microfluidic systems |
US10672503B2 (en) | 2012-03-05 | 2020-06-02 | Opko Diagnostics, Llc | Methods and apparatuses for conducting analyses |
US11761962B2 (en) | 2014-03-28 | 2023-09-19 | Opko Diagnostics, Llc | Compositions and methods related to diagnosis of prostate cancer |
US11921115B2 (en) | 2015-03-27 | 2024-03-05 | Opko Diagnostics, Llc | Prostate antigen standards and uses thereof |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2001077641A1 (en) * | 2000-04-06 | 2001-10-18 | Caliper Technologies Corp. | Microfluidic devices and systems incorporating cover layers |
JP4909130B2 (en) * | 2007-03-07 | 2012-04-04 | 積水化学工業株式会社 | Micropump device and microfluidic device |
GB201109203D0 (en) * | 2011-06-01 | 2011-07-13 | Carclo Technical Plastics Ltd | Fluid flow control |
US20160325282A1 (en) * | 2013-12-26 | 2016-11-10 | Kyocera Corporation | Liquid specimen sensor, liquid specimen sensor unit, and liquid specimen testing method |
JP7010603B2 (en) * | 2017-05-31 | 2022-01-26 | シスメックス株式会社 | Specimen processing chip |
WO2021006028A1 (en) * | 2019-07-08 | 2021-01-14 | 積水化学工業株式会社 | Liquid supply method and inspection chip |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0262328A2 (en) * | 1986-09-29 | 1988-04-06 | Abbott Laboratories | Chromatographic test strip for determining ligands and receptors |
EP0281201A1 (en) * | 1987-03-03 | 1988-09-07 | PB Diagnostic Systems, Inc. | Self contained immunoassay element |
EP0306336A2 (en) * | 1987-09-04 | 1989-03-08 | Syntex (U.S.A.) Inc. | Multiple port assay device |
EP0314499A1 (en) * | 1987-10-30 | 1989-05-03 | Unilever Plc | Devices and methods for chemical testing |
WO1993010457A1 (en) * | 1991-11-11 | 1993-05-27 | British Technonology Group Limited | Liquid transfer assay devices |
EP0545500A1 (en) * | 1991-12-05 | 1993-06-09 | Eastman Kodak Company | Capillary collection devices |
US5256372A (en) * | 1987-11-06 | 1993-10-26 | Idexx Corporation | Dipstick test device including a removable filter assembly |
EP0590695A2 (en) * | 1989-03-23 | 1994-04-06 | Roger Abraham Bunce | Liquid transfer devices |
-
1996
- 1996-07-30 CA CA002228485A patent/CA2228485A1/en not_active Abandoned
- 1996-07-30 WO PCT/EP1996/003380 patent/WO1997006437A1/en not_active Application Discontinuation
- 1996-07-30 JP JP9508098A patent/JPH11510601A/en active Pending
- 1996-07-30 EP EP96928401A patent/EP0843817A1/en not_active Withdrawn
- 1996-07-30 KR KR1019980700734A patent/KR19990036069A/en not_active Application Discontinuation
- 1996-07-30 AU AU67887/96A patent/AU6788796A/en not_active Abandoned
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0262328A2 (en) * | 1986-09-29 | 1988-04-06 | Abbott Laboratories | Chromatographic test strip for determining ligands and receptors |
EP0281201A1 (en) * | 1987-03-03 | 1988-09-07 | PB Diagnostic Systems, Inc. | Self contained immunoassay element |
EP0306336A2 (en) * | 1987-09-04 | 1989-03-08 | Syntex (U.S.A.) Inc. | Multiple port assay device |
EP0314499A1 (en) * | 1987-10-30 | 1989-05-03 | Unilever Plc | Devices and methods for chemical testing |
US5256372A (en) * | 1987-11-06 | 1993-10-26 | Idexx Corporation | Dipstick test device including a removable filter assembly |
EP0590695A2 (en) * | 1989-03-23 | 1994-04-06 | Roger Abraham Bunce | Liquid transfer devices |
WO1993010457A1 (en) * | 1991-11-11 | 1993-05-27 | British Technonology Group Limited | Liquid transfer assay devices |
EP0545500A1 (en) * | 1991-12-05 | 1993-06-09 | Eastman Kodak Company | Capillary collection devices |
Cited By (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999047255A1 (en) * | 1998-03-17 | 1999-09-23 | Cepheid | Unitary chemical processing device |
EP1391241A1 (en) * | 1999-04-21 | 2004-02-25 | Clinical Micro Sensors | The use of microfluidic systems in the electrochemical detection of target analytes |
WO2001026813A2 (en) * | 1999-10-08 | 2001-04-19 | Micronics, Inc. | Microfluidics without electrically of mechanically operated pumps |
WO2001026813A3 (en) * | 1999-10-08 | 2001-11-22 | Micronics Inc | Microfluidics without electrically of mechanically operated pumps |
US6743399B1 (en) | 1999-10-08 | 2004-06-01 | Micronics, Inc. | Pumpless microfluidics |
US8067246B2 (en) | 2001-12-12 | 2011-11-29 | Tyrian Diagnostics Limited | Diagnostic testing process |
EP1461615A1 (en) * | 2001-12-12 | 2004-09-29 | Proteome Systems Intellectual Property Pty Ltd. | Diagnostic testing process |
EP1461615A4 (en) * | 2001-12-12 | 2005-01-26 | Proteome Systems Intellectual | Diagnostic testing process |
US8765075B2 (en) | 2003-09-10 | 2014-07-01 | Abbott Point Of Care, Inc. | Immunoassay reagent composition |
US8216853B2 (en) | 2003-09-10 | 2012-07-10 | Abbott Point Of Care Inc. | Immunoassay device with improved sample closure |
WO2006039542A1 (en) * | 2004-09-30 | 2006-04-13 | Quidel Corporation | Analytical devices with primary and secondary flow paths |
US7871568B2 (en) | 2006-01-23 | 2011-01-18 | Quidel Corporation | Rapid test apparatus |
US7794656B2 (en) | 2006-01-23 | 2010-09-14 | Quidel Corporation | Device for handling and analysis of a biological sample |
US9138743B2 (en) | 2006-10-04 | 2015-09-22 | University Of Washington | Method and device for rapid parallel microfluidic molecular affinity assays |
US8101403B2 (en) | 2006-10-04 | 2012-01-24 | University Of Washington | Method and device for rapid parallel microfluidic molecular affinity assays |
US10408824B2 (en) | 2007-05-04 | 2019-09-10 | Opko Diagnostics, Llc | Fluidic connectors and microfluidic systems |
US10775369B2 (en) | 2007-05-04 | 2020-09-15 | Opko Diagnostics, Llc | Fluidic systems for analyses |
US9827564B2 (en) | 2009-02-02 | 2017-11-28 | Opko Diagnostics, Llc | Fluidic systems and methods for analyses |
US9827563B2 (en) | 2009-02-02 | 2017-11-28 | Opko Diagnostics, Llc | Fluidic systems and methods for analyses |
US9643182B2 (en) | 2010-04-16 | 2017-05-09 | Opko Diagnostics, Llc | Systems and devices for analysis of samples |
US9981266B2 (en) | 2010-04-16 | 2018-05-29 | Opko Diagnostics, Llc | Feedback control in microfluidic systems |
US11458473B2 (en) | 2010-04-16 | 2022-10-04 | Opko Diagnostics, Llc | Systems and devices for analysis of samples |
US10456784B2 (en) | 2010-04-16 | 2019-10-29 | Opko Diagnostics, Llc | Systems and devices for analysis of samples |
US9289764B2 (en) | 2010-12-20 | 2016-03-22 | Boehringer Ingelheim Microparts Gmbh | Method for mixing at least one sample solution having at least one reagent, and device |
US10105478B2 (en) | 2012-01-24 | 2018-10-23 | Koninklijke Philips N.V. | Analysis cartridge with filter unit |
WO2013111026A1 (en) * | 2012-01-24 | 2013-08-01 | Koninklijke Philips N.V. | Analysis cartridge with filter unit |
US10672503B2 (en) | 2012-03-05 | 2020-06-02 | Opko Diagnostics, Llc | Methods and apparatuses for conducting analyses |
US11761962B2 (en) | 2014-03-28 | 2023-09-19 | Opko Diagnostics, Llc | Compositions and methods related to diagnosis of prostate cancer |
US11921115B2 (en) | 2015-03-27 | 2024-03-05 | Opko Diagnostics, Llc | Prostate antigen standards and uses thereof |
DE102018207548B3 (en) | 2018-05-16 | 2019-06-19 | Robert Bosch Gmbh | Sensor device with a hydrophobic and / or anti-adhesive protective layer and method for producing such a sensor device |
Also Published As
Publication number | Publication date |
---|---|
CA2228485A1 (en) | 1997-02-20 |
JPH11510601A (en) | 1999-09-14 |
KR19990036069A (en) | 1999-05-25 |
EP0843817A1 (en) | 1998-05-27 |
AU6788796A (en) | 1997-03-05 |
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