WO1996033805A3 - Pipetting needle and rinse station therefor for fluid transfer under inert atmosphere operations - Google Patents

Pipetting needle and rinse station therefor for fluid transfer under inert atmosphere operations Download PDF

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Publication number
WO1996033805A3
WO1996033805A3 PCT/IB1996/000484 IB9600484W WO9633805A3 WO 1996033805 A3 WO1996033805 A3 WO 1996033805A3 IB 9600484 W IB9600484 W IB 9600484W WO 9633805 A3 WO9633805 A3 WO 9633805A3
Authority
WO
WIPO (PCT)
Prior art keywords
pipetting
needle
inert atmosphere
under inert
pipetting needle
Prior art date
Application number
PCT/IB1996/000484
Other languages
French (fr)
Other versions
WO1996033805A2 (en
Inventor
Romaine Maiefski
John Cargill
Original Assignee
Ontogen Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ontogen Corp filed Critical Ontogen Corp
Priority to AU59830/96A priority Critical patent/AU5983096A/en
Publication of WO1996033805A2 publication Critical patent/WO1996033805A2/en
Publication of WO1996033805A3 publication Critical patent/WO1996033805A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1079—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices with means for piercing stoppers or septums
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00279—Features relating to reactor vessels
    • B01J2219/00331—Details of the reactor vessels
    • B01J2219/00333—Closures attached to the reactor vessels
    • B01J2219/00335—Septa
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
    • B01J2219/00277—Apparatus
    • B01J2219/00351—Means for dispensing and evacuation of reagents
    • B01J2219/00373—Hollow needles
    • C—CHEMISTRY; METALLURGY
    • C40—COMBINATORIAL TECHNOLOGY
    • C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
    • C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
    • C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Feeding, Discharge, Calcimining, Fusing, And Gas-Generation Devices (AREA)
  • Cleaning In General (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

A coaxial needle assembly (20) for pipetting reagents under inert atmosphere, as well as a rinsing station (60, 70) is described. A preferred coaxial needle assembly (20) includes a non-coring pipetting needle (22) and a gas pressurization needle (32) coaxial with, and of larger diameter than the pipetting needle (22). In one embodiment, rinse stations (60, 70) that employ a pipetting syringe to deliver cleaning solvents to cleanse the interior of a contaminated pipetting needle (20) are described. In an alternative embodiment, rinse stations (60, 70) that use cleaning solvents cleanse the interior and exterior of a contaminated pipetting needle (20) are described.
PCT/IB1996/000484 1995-04-17 1996-04-17 Pipetting needle and rinse station therefor for fluid transfer under inert atmosphere operations WO1996033805A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU59830/96A AU5983096A (en) 1995-04-17 1996-04-17 Pipetting needle and rinse station therefor for fluid transf er under inert atmosphere operations

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US42314195A 1995-04-17 1995-04-17
US42314295A 1995-04-17 1995-04-17
US08/423,142 1995-04-17
US08/423,141 1995-04-17

Publications (2)

Publication Number Publication Date
WO1996033805A2 WO1996033805A2 (en) 1996-10-31
WO1996033805A3 true WO1996033805A3 (en) 1997-01-09

Family

ID=27025891

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB1996/000484 WO1996033805A2 (en) 1995-04-17 1996-04-17 Pipetting needle and rinse station therefor for fluid transfer under inert atmosphere operations

Country Status (3)

Country Link
AU (1) AU5983096A (en)
CA (1) CA2218366A1 (en)
WO (1) WO1996033805A2 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2001527642A (en) * 1997-01-17 2001-12-25 スミスクライン・ビーチャム・コーポレイション Apparatus and method for arranging beads
WO2002066151A2 (en) 2001-01-26 2002-08-29 Symyx Technologies, Inc. Apparatus and methods for parallel processing of multiple reaction mixtures
US20230211349A1 (en) * 2020-05-01 2023-07-06 Agilent Technologies, Inc. Pipette tip washing devices and methods

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310010A (en) * 1980-01-07 1982-01-12 Svoboda Melora J Apparatus for cleaning closed-end tubes
US4422466A (en) * 1981-08-07 1983-12-27 Schicker & Schafer Arrangement for cleaning containers of diverse shapes
US4748007A (en) * 1985-11-27 1988-05-31 Vetrodyne, Inc. Endoscope disinfecting and storing device
US4961440A (en) * 1988-07-02 1990-10-09 Schering Agrochemicals Ltd. Chemical dispensing apparatus
US4989623A (en) * 1989-12-01 1991-02-05 Akzo N.V. Apparatus and method for cleaning reagent delivery probes
US5025818A (en) * 1989-09-06 1991-06-25 Kalar David L Paint pump cleaning system
US5066336A (en) * 1989-12-01 1991-11-19 Akzo N.V. Method for cleaning reagent delivery probes
US5133373A (en) * 1989-12-01 1992-07-28 Akzo N.V. Apparatus and method for cleaning reagent delivery probes
US5156813A (en) * 1990-07-13 1992-10-20 Medical Laboratory Automation, Inc. Cup for use with a pipette probe
US5186194A (en) * 1990-08-24 1993-02-16 Olympus Optical Co., Ltd. Probe washing vessel
US5201331A (en) * 1991-03-08 1993-04-13 R. R. Donnelley & Sons Co. Vapor containment apparatus and method
US5288467A (en) * 1988-06-06 1994-02-22 Hans Biermaier Cleaning and disinfecting machine for medical equipment and instruments, anesthetic tubes, catheters, and endoscopes
US5474744A (en) * 1993-10-28 1995-12-12 Hoffmann-La Roche Inc. Automatic pipetting device with cleaning mechanism

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4310010A (en) * 1980-01-07 1982-01-12 Svoboda Melora J Apparatus for cleaning closed-end tubes
US4422466A (en) * 1981-08-07 1983-12-27 Schicker & Schafer Arrangement for cleaning containers of diverse shapes
US4748007A (en) * 1985-11-27 1988-05-31 Vetrodyne, Inc. Endoscope disinfecting and storing device
US5288467A (en) * 1988-06-06 1994-02-22 Hans Biermaier Cleaning and disinfecting machine for medical equipment and instruments, anesthetic tubes, catheters, and endoscopes
US4961440A (en) * 1988-07-02 1990-10-09 Schering Agrochemicals Ltd. Chemical dispensing apparatus
US5025818A (en) * 1989-09-06 1991-06-25 Kalar David L Paint pump cleaning system
US5066336A (en) * 1989-12-01 1991-11-19 Akzo N.V. Method for cleaning reagent delivery probes
US5133373A (en) * 1989-12-01 1992-07-28 Akzo N.V. Apparatus and method for cleaning reagent delivery probes
US4989623A (en) * 1989-12-01 1991-02-05 Akzo N.V. Apparatus and method for cleaning reagent delivery probes
US5156813A (en) * 1990-07-13 1992-10-20 Medical Laboratory Automation, Inc. Cup for use with a pipette probe
US5186194A (en) * 1990-08-24 1993-02-16 Olympus Optical Co., Ltd. Probe washing vessel
US5201331A (en) * 1991-03-08 1993-04-13 R. R. Donnelley & Sons Co. Vapor containment apparatus and method
US5474744A (en) * 1993-10-28 1995-12-12 Hoffmann-La Roche Inc. Automatic pipetting device with cleaning mechanism

Also Published As

Publication number Publication date
WO1996033805A2 (en) 1996-10-31
CA2218366A1 (en) 1996-10-31
AU5983096A (en) 1996-11-18

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