WO1996022084A3 - Formulation adhesive polymere contenant des particules sorbantes - Google Patents

Formulation adhesive polymere contenant des particules sorbantes Download PDF

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Publication number
WO1996022084A3
WO1996022084A3 PCT/US1996/000740 US9600740W WO9622084A3 WO 1996022084 A3 WO1996022084 A3 WO 1996022084A3 US 9600740 W US9600740 W US 9600740W WO 9622084 A3 WO9622084 A3 WO 9622084A3
Authority
WO
WIPO (PCT)
Prior art keywords
drug
excipient
formulation containing
polymer adhesive
adhesive formulation
Prior art date
Application number
PCT/US1996/000740
Other languages
English (en)
Other versions
WO1996022084A2 (fr
Inventor
Russell D Beste
Chia-Ming Chiang
Jun Xia
Original Assignee
Cygnus Therapeutic Systems
Russell D Beste
Chiang Chia Ming
Jun Xia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cygnus Therapeutic Systems, Russell D Beste, Chiang Chia Ming, Jun Xia filed Critical Cygnus Therapeutic Systems
Priority to AU47611/96A priority Critical patent/AU4761196A/en
Publication of WO1996022084A2 publication Critical patent/WO1996022084A2/fr
Publication of WO1996022084A3 publication Critical patent/WO1996022084A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
    • A61K9/7061—Polyacrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
    • A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
    • A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
    • A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
    • A61K9/7069—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained otherwise than by reactions only involving carbon to carbon unsaturated bonds, e.g. polysiloxane, polyesters, polyurethane, polyethylene oxide

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)

Abstract

Les propriétés de fluage à froid de couches de timbres d'administration transcutanée ou à travers les muqueuses composées d'adhésifs polymères plastifiés par un médicament-excipient, exempts de groupes fonctionnels, sont maintenues à un niveau acceptable par l'inclusion d'une matière sorbante dans le mélange adhésif/médicament-excipient qui absorbe une partie du médicament-excipient et empêche donc le médicament-excipient de trop entraver les propriétés de fluage à froid de l'adhésif.
PCT/US1996/000740 1995-01-19 1996-01-19 Formulation adhesive polymere contenant des particules sorbantes WO1996022084A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU47611/96A AU4761196A (en) 1995-01-19 1996-01-19 Polymer adhesive formulation containing sorbent particles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37442295A 1995-01-19 1995-01-19
US08/374,422 1995-01-19

Publications (2)

Publication Number Publication Date
WO1996022084A2 WO1996022084A2 (fr) 1996-07-25
WO1996022084A3 true WO1996022084A3 (fr) 1996-10-17

Family

ID=23476748

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1996/000740 WO1996022084A2 (fr) 1995-01-19 1996-01-19 Formulation adhesive polymere contenant des particules sorbantes

Country Status (2)

Country Link
AU (1) AU4761196A (fr)
WO (1) WO1996022084A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9186335B2 (en) 2002-07-30 2015-11-17 Ucb Pharma Gmbh Hot melt TTS for administering rotigotine

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19814084B4 (de) 1998-03-30 2005-12-22 Lts Lohmann Therapie-Systeme Ag D2-Agonist enthaltendes transdermales therapeutisches System zur Behandlung des Parkinson-Syndroms und Verfahren zu seiner Herstellung
DE19940238A1 (de) 1999-08-25 2001-03-01 Lohmann Therapie Syst Lts Wirkstoffhaltiges therapeutisches System zur Applikation auf der Haut mit mindestens zwei polymerhaltigen Schichten

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991014463A1 (fr) * 1990-03-28 1991-10-03 Noven Pharmaceuticals, Inc. Procede d'administration transcutanee d'une substance medicamenteuse et dispositif a cet effet
EP0450986A2 (fr) * 1990-04-06 1991-10-09 Sekisui Kagaku Kogyo Kabushiki Kaisha Préparation pharmaceutique pour l'administration percutanée de nitroglycérine
EP0481443A1 (fr) * 1990-10-17 1992-04-22 Vectorpharma International S.P.A. Compositions transdermiques thérapeutiques
WO1994007468A1 (fr) * 1992-10-05 1994-04-14 Cygnus Therapeutic Systems Matrice a deux phases pour dispositif d'apport medicamenteux a liberation prolongee
WO1995001766A1 (fr) * 1993-07-09 1995-01-19 Cygnus Therapeutic Systems Procede et dispositif therapeutique d'administration de substitut de la nicotine par voie transcutanee ou buccale

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1991014463A1 (fr) * 1990-03-28 1991-10-03 Noven Pharmaceuticals, Inc. Procede d'administration transcutanee d'une substance medicamenteuse et dispositif a cet effet
EP0450986A2 (fr) * 1990-04-06 1991-10-09 Sekisui Kagaku Kogyo Kabushiki Kaisha Préparation pharmaceutique pour l'administration percutanée de nitroglycérine
EP0481443A1 (fr) * 1990-10-17 1992-04-22 Vectorpharma International S.P.A. Compositions transdermiques thérapeutiques
WO1994007468A1 (fr) * 1992-10-05 1994-04-14 Cygnus Therapeutic Systems Matrice a deux phases pour dispositif d'apport medicamenteux a liberation prolongee
WO1995001766A1 (fr) * 1993-07-09 1995-01-19 Cygnus Therapeutic Systems Procede et dispositif therapeutique d'administration de substitut de la nicotine par voie transcutanee ou buccale

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9186335B2 (en) 2002-07-30 2015-11-17 Ucb Pharma Gmbh Hot melt TTS for administering rotigotine

Also Published As

Publication number Publication date
AU4761196A (en) 1996-08-07
WO1996022084A2 (fr) 1996-07-25

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