WO1996015237A3 - Delivery system - Google Patents

Delivery system Download PDF

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Publication number
WO1996015237A3
WO1996015237A3 PCT/GB1995/002639 GB9502639W WO9615237A3 WO 1996015237 A3 WO1996015237 A3 WO 1996015237A3 GB 9502639 W GB9502639 W GB 9502639W WO 9615237 A3 WO9615237 A3 WO 9615237A3
Authority
WO
WIPO (PCT)
Prior art keywords
recipient
delivery system
vaccine
organism
phytophagous
Prior art date
Application number
PCT/GB1995/002639
Other languages
French (fr)
Other versions
WO1996015237A2 (en
Inventor
Robert Edward Sinden
Julian Moray Crampton
Original Assignee
Imperial College
Univ Liverpool
Robert Edward Sinden
Julian Moray Crampton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial College, Univ Liverpool, Robert Edward Sinden, Julian Moray Crampton filed Critical Imperial College
Priority to EP95936657A priority Critical patent/EP0785997A2/en
Priority to AU38511/95A priority patent/AU3851195A/en
Priority to BR9509646A priority patent/BR9509646A/en
Publication of WO1996015237A2 publication Critical patent/WO1996015237A2/en
Publication of WO1996015237A3 publication Critical patent/WO1996015237A3/en
Priority to US09/882,302 priority patent/US20020124274A1/en
Priority to US10/375,050 priority patent/US20030192067A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/02—Preparation of hybrid cells by fusion of two or more cells, e.g. protoplast fusion
    • C12N15/03—Bacteria
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C07K14/445—Plasmodium
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/01—Animal expressing industrially exogenous proteins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Environmental Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Animal Husbandry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A delivery system for a recipient comprising an organism containing a vaccine for the recipient and wherein the vaccine is prepared outside of the recipient and is capable of being transmitted by and from the organism to the recipient is described. A preferred embodiment comprises a transgenic phytophagous or haematophagous insect whose salivary glands comprise a gene capable of expressing a desired antigen.
PCT/GB1995/002639 1994-11-11 1995-11-10 Delivery system WO1996015237A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
EP95936657A EP0785997A2 (en) 1994-11-11 1995-11-10 Delivery system
AU38511/95A AU3851195A (en) 1994-11-11 1995-11-10 Delivery system
BR9509646A BR9509646A (en) 1994-11-11 1995-11-10 Delivery system to a recipient transgenic organism vaccine derived from a transgenic organism use of a transgenic organism insect phytophagous or hematophagous transgenic recipient and method of vaccination of a recipient
US09/882,302 US20020124274A1 (en) 1994-11-11 2001-06-18 Delivery system
US10/375,050 US20030192067A1 (en) 1994-11-11 2003-02-28 Delivery system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9422827.7 1994-11-11
GB9422827A GB9422827D0 (en) 1994-11-11 1994-11-11 Delivery system

Publications (2)

Publication Number Publication Date
WO1996015237A2 WO1996015237A2 (en) 1996-05-23
WO1996015237A3 true WO1996015237A3 (en) 1996-06-27

Family

ID=10764269

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB1995/002639 WO1996015237A2 (en) 1994-11-11 1995-11-10 Delivery system

Country Status (8)

Country Link
EP (1) EP0785997A2 (en)
KR (1) KR970707278A (en)
CN (1) CN1171813A (en)
AU (1) AU3851195A (en)
BR (1) BR9509646A (en)
CA (1) CA2205029A1 (en)
GB (1) GB9422827D0 (en)
WO (1) WO1996015237A2 (en)

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992019758A1 (en) * 1991-05-08 1992-11-12 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Transmission-blocking vaccine against malaria
WO1994001552A1 (en) * 1992-07-10 1994-01-20 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Target antigens of transmission blocking antibodies for malaria parsites
WO1994012640A1 (en) * 1992-11-20 1994-06-09 Stichting Katholieke Universiteit RECOMBINANT NUCLEIC ACID, POLYPEPTIDE MATERIAL CODED THEREBY AND TRANSMISSION BLOCKING VACCINE BASED THEREON FOR CONTROLLING THE MALARIA PARASITE $i(PLASMODIUM FALCIPARUM )
WO1994017187A1 (en) * 1993-01-29 1994-08-04 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services CLONING AND EXPRESSION OF PLASMODIUM FALCIPARUM TRANSMISSION-BLOCKING TARGET ANTIGEN, Pfs230

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992019758A1 (en) * 1991-05-08 1992-11-12 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Transmission-blocking vaccine against malaria
WO1994001552A1 (en) * 1992-07-10 1994-01-20 The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Target antigens of transmission blocking antibodies for malaria parsites
WO1994012640A1 (en) * 1992-11-20 1994-06-09 Stichting Katholieke Universiteit RECOMBINANT NUCLEIC ACID, POLYPEPTIDE MATERIAL CODED THEREBY AND TRANSMISSION BLOCKING VACCINE BASED THEREON FOR CONTROLLING THE MALARIA PARASITE $i(PLASMODIUM FALCIPARUM )
WO1994017187A1 (en) * 1993-01-29 1994-08-04 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services CLONING AND EXPRESSION OF PLASMODIUM FALCIPARUM TRANSMISSION-BLOCKING TARGET ANTIGEN, Pfs230

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
J.M. CRAMPTON ET AL.: "Molecular biology approaches to the study of vectors in relation to malaria control", MEM. INST. OSWALDO CRUZ, RIO DE JANEIRO, vol. 87, no. Suppl. III, pages 43 - 49 *
J.M. CRAMPTON ET AL.: "Transgenic mosquitoes: a future vector control strategy?", PARASITOLOGY TODAY, vol. 6, no. 2, pages 31 - 36 *
J.M. CRAMPTON: "Approaches to vector control: new and trusted", TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, vol. 88, pages 141 - 143 *

Also Published As

Publication number Publication date
GB9422827D0 (en) 1995-01-04
WO1996015237A2 (en) 1996-05-23
AU3851195A (en) 1996-06-06
CA2205029A1 (en) 1996-05-23
EP0785997A2 (en) 1997-07-30
BR9509646A (en) 1997-09-16
KR970707278A (en) 1997-12-01
CN1171813A (en) 1998-01-28

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