WO1996011680A3 - Utilisation d'agonistes de gaba dans le traitement de vomissements - Google Patents
Utilisation d'agonistes de gaba dans le traitement de vomissements Download PDFInfo
- Publication number
- WO1996011680A3 WO1996011680A3 PCT/EP1995/004025 EP9504025W WO9611680A3 WO 1996011680 A3 WO1996011680 A3 WO 1996011680A3 EP 9504025 W EP9504025 W EP 9504025W WO 9611680 A3 WO9611680 A3 WO 9611680A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- emesis
- treatment
- gaba agonists
- agonists
- gaba
- Prior art date
Links
- 239000003477 4 aminobutyric acid receptor stimulating agent Substances 0.000 title abstract 2
- 206010047700 Vomiting Diseases 0.000 title abstract 2
- 239000000556 agonist Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU37458/95A AU3745895A (en) | 1994-10-14 | 1995-10-12 | Use of gaba antagonists in the treatment of emesis |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9420784A GB9420784D0 (en) | 1994-10-14 | 1994-10-14 | Medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1996011680A2 WO1996011680A2 (fr) | 1996-04-25 |
WO1996011680A3 true WO1996011680A3 (fr) | 1996-06-27 |
Family
ID=10762886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1995/004025 WO1996011680A2 (fr) | 1994-10-14 | 1995-10-12 | Utilisation d'agonistes de gaba dans le traitement de vomissements |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU3745895A (fr) |
GB (1) | GB9420784D0 (fr) |
WO (1) | WO1996011680A2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE41920E1 (en) | 1996-07-24 | 2010-11-09 | Warner-Lambert Company Llc | Isobutylgaba and its derivatives for the treatment of pain |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6127418A (en) * | 1997-08-20 | 2000-10-03 | Warner-Lambert Company | GABA analogs to prevent and treat gastrointestinal damage |
AU8668598A (en) | 1997-08-20 | 1999-03-08 | University Of Oklahoma, The | Gaba analogs to prevent and treat gastrointestinal damage |
EP0974351A3 (fr) * | 1998-04-24 | 2000-12-13 | Jouveinal | Médicament pour la prévention et le traitement des dommages gastrointestinaux |
PT1077692E (pt) * | 1998-05-15 | 2004-12-31 | Warner Lambert Co | Preparacoes farmaceuticas estabilizadas de derivados do acido aminobutirico e processos para a sua preparacao |
EP1031350A1 (fr) * | 1999-02-23 | 2000-08-30 | Warner-Lambert Company | Utilisation d'un analogue de la gabapentine pour la fabrication d'un médicament pour la prevention et le traitement des douleurs viscérales |
SE9904508D0 (sv) | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
US7319095B2 (en) | 1999-12-09 | 2008-01-15 | Astrazeneca Ab | Use of GABAB receptor agonists |
SE9904507D0 (sv) | 1999-12-09 | 1999-12-09 | Astra Ab | New compounds |
AR033779A1 (es) | 2001-06-08 | 2004-01-07 | Astrazeneca Ab | Compuestos utiles en la enfermedad de reflujo |
US20050090554A1 (en) * | 2003-09-12 | 2005-04-28 | John Devane | Treatment of gastroparesis and nonulcer dyspepsia with GABAB agonists |
WO2017046117A1 (fr) | 2015-09-15 | 2017-03-23 | Abbvie Inc. | Isoxazolopyridazinones et isothiazolopyridazinones substituées et procédés d'utilisation |
US10918632B2 (en) * | 2016-09-07 | 2021-02-16 | The Children's Hospital Of Philadelphia | Nonselective metabotropic glutamate receptor activators for treatment of anorexia nervosa and binge eating disorder |
CN111603560A (zh) * | 2020-06-22 | 2020-09-01 | 泉州台商投资区秋鑫茶业有限公司 | 茶叶γ-氨基丁酸在肿瘤放射治疗上的应用 |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3896149A (en) * | 1972-06-07 | 1975-07-22 | Sakai Chemical Industry Co | Novel pyrrolidone derivatives and manufacturing the same |
EP0082369A1 (fr) * | 1981-12-19 | 1983-06-29 | MERCK PATENT GmbH | Imidazo (4,5-c) pyridines, compositions pharmaceutiques les contenant et procédé pour leur préparation |
GB2185483A (en) * | 1986-01-21 | 1987-07-22 | Nippon Shinyaku Co Ltd | Pyroglutamide derivatives |
US4952573A (en) * | 1988-03-23 | 1990-08-28 | Laboratoirs Alcon S.A. | Compounds having GABA like activity, and use of same in tissue irrigating solutions |
US5182290A (en) * | 1991-08-27 | 1993-01-26 | Neurogen Corporation | Certain oxazoloquinolinones; a new class of GABA brain receptor ligands |
WO1993011138A1 (fr) * | 1991-12-02 | 1993-06-10 | John Wyeth & Brother Limited | Derives d'amines contenant une fraction d'acide phosphonique, phosphoreux ou phosphinique |
WO1993022314A1 (fr) * | 1992-04-30 | 1993-11-11 | Neurogen Corporation | Certains imidazopyrazinediones d'aryle et de cycloalkyle fusionnes; nouvelle categorie de ligands de neurorecepteurs de gaba |
US5281747A (en) * | 1989-05-13 | 1994-01-25 | Ciba-Geigy Corporation | Substituted aminoalkylphosphinic acids |
WO1994025016A1 (fr) * | 1993-04-23 | 1994-11-10 | Glaxo Group Limited | NOUVELLE APPLICATION MEDICALE D'AGONISTES D'ACIDE η-AMINOBUTYRIQUE |
-
1994
- 1994-10-14 GB GB9420784A patent/GB9420784D0/en active Pending
-
1995
- 1995-10-12 WO PCT/EP1995/004025 patent/WO1996011680A2/fr active Application Filing
- 1995-10-12 AU AU37458/95A patent/AU3745895A/en not_active Abandoned
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3896149A (en) * | 1972-06-07 | 1975-07-22 | Sakai Chemical Industry Co | Novel pyrrolidone derivatives and manufacturing the same |
EP0082369A1 (fr) * | 1981-12-19 | 1983-06-29 | MERCK PATENT GmbH | Imidazo (4,5-c) pyridines, compositions pharmaceutiques les contenant et procédé pour leur préparation |
GB2185483A (en) * | 1986-01-21 | 1987-07-22 | Nippon Shinyaku Co Ltd | Pyroglutamide derivatives |
US4952573A (en) * | 1988-03-23 | 1990-08-28 | Laboratoirs Alcon S.A. | Compounds having GABA like activity, and use of same in tissue irrigating solutions |
US5281747A (en) * | 1989-05-13 | 1994-01-25 | Ciba-Geigy Corporation | Substituted aminoalkylphosphinic acids |
US5182290A (en) * | 1991-08-27 | 1993-01-26 | Neurogen Corporation | Certain oxazoloquinolinones; a new class of GABA brain receptor ligands |
WO1993011138A1 (fr) * | 1991-12-02 | 1993-06-10 | John Wyeth & Brother Limited | Derives d'amines contenant une fraction d'acide phosphonique, phosphoreux ou phosphinique |
WO1993022314A1 (fr) * | 1992-04-30 | 1993-11-11 | Neurogen Corporation | Certains imidazopyrazinediones d'aryle et de cycloalkyle fusionnes; nouvelle categorie de ligands de neurorecepteurs de gaba |
WO1994025016A1 (fr) * | 1993-04-23 | 1994-11-10 | Glaxo Group Limited | NOUVELLE APPLICATION MEDICALE D'AGONISTES D'ACIDE η-AMINOBUTYRIQUE |
Non-Patent Citations (1)
Title |
---|
"Baclofen for intractable vomiting in muscular dystrophy", LANCET, pages 227, XP000563383 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
USRE41920E1 (en) | 1996-07-24 | 2010-11-09 | Warner-Lambert Company Llc | Isobutylgaba and its derivatives for the treatment of pain |
Also Published As
Publication number | Publication date |
---|---|
GB9420784D0 (en) | 1994-11-30 |
AU3745895A (en) | 1996-05-06 |
WO1996011680A2 (fr) | 1996-04-25 |
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