WO1996007397A2 - Delivery of solid drug compositions - Google Patents
Delivery of solid drug compositions Download PDFInfo
- Publication number
- WO1996007397A2 WO1996007397A2 PCT/IB1995/000778 IB9500778W WO9607397A2 WO 1996007397 A2 WO1996007397 A2 WO 1996007397A2 IB 9500778 W IB9500778 W IB 9500778W WO 9607397 A2 WO9607397 A2 WO 9607397A2
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- drug
- composition
- solid
- carrier
- patient
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
- A61K38/09—Luteinising hormone-releasing hormone [LHRH], i.e. Gonadotropin-releasing hormone [GnRH]; Related peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/25—Growth hormone-releasing factor [GH-RF] (Somatoliberin)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/28—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/31—Somatostatins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2013—Organic compounds, e.g. phospholipids, fats
- A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0069—Devices for implanting pellets, e.g. markers or solid medicaments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M5/14248—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body of the skin patch type
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/145—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons
- A61M5/1452—Pressure infusion, e.g. using pumps using pressurised reservoirs, e.g. pressurised by means of pistons pressurised by means of pistons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/02—Drugs for disorders of the endocrine system of the hypothalamic hormones, e.g. TRH, GnRH, CRH, GRH, somatostatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/14—Details; Accessories therefor
- A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
- A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
- A61J1/2006—Piercing means
- A61J1/201—Piercing means having one piercing end
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/14—Infusion devices, e.g. infusing by gravity; Blood infusion; Accessories therefor
- A61M5/142—Pressure infusion, e.g. using pumps
- A61M5/14244—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body
- A61M2005/14268—Pressure infusion, e.g. using pumps adapted to be carried by the patient, e.g. portable on the body with a reusable and a disposable component
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31531—Microsyringes, e.g. having piston bore diameter close or equal to needle shaft diameter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31566—Means improving security or handling thereof
- A61M5/31573—Accuracy improving means
- A61M5/31575—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/3159—Dose expelling manners
- A61M5/31593—Multi-dose, i.e. individually set dose repeatedly administered from the same medicament reservoir
- A61M5/31595—Pre-defined multi-dose administration by repeated overcoming of means blocking the free advancing movement of piston rod, e.g. by tearing or de-blocking
Abstract
Description
Claims
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP95930675A EP0778767B1 (en) | 1994-09-02 | 1995-08-31 | Delivery of solid drug compositions |
KR10-2001-7005475A KR100491424B1 (en) | 1994-09-02 | 1995-08-31 | Delivery of Solid Drug Compositions |
DK95930675T DK0778767T3 (en) | 1994-09-02 | 1995-08-31 | Delivery of solid drug preparations |
DE1995629415 DE69529415T2 (en) | 1994-09-02 | 1995-08-31 | ADMINISTRATION OF SOLID DRUG PREPARATIONS |
JP50935696A JP4072867B2 (en) | 1994-09-02 | 1995-08-31 | Supply of solid drug composition |
AU33981/95A AU712916B2 (en) | 1994-09-02 | 1995-08-31 | Delivery of solid drug compositions |
AT95930675T ATE230977T1 (en) | 1994-09-02 | 1995-08-31 | ADMINISTRATION OF SOLID MEDICINAL PREPARATIONS |
BR9508688A BR9508688A (en) | 1994-09-02 | 1995-08-31 | Release of solid drug compositions |
CA 2198916 CA2198916C (en) | 1994-09-02 | 1995-08-31 | Delivery of solid drug compositions |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/300,713 | 1994-09-02 | ||
US08/300,713 US5582591A (en) | 1994-09-02 | 1994-09-02 | Delivery of solid drug compositions |
US31746594A | 1994-10-04 | 1994-10-04 | |
US08/317,465 | 1994-10-04 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1996007397A2 true WO1996007397A2 (en) | 1996-03-14 |
WO1996007397A3 WO1996007397A3 (en) | 1996-08-15 |
Family
ID=26971933
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB1995/000778 WO1996007397A2 (en) | 1994-09-02 | 1995-08-31 | Delivery of solid drug compositions |
Country Status (16)
Country | Link |
---|---|
US (2) | US5582591A (en) |
EP (3) | EP1498150B1 (en) |
JP (1) | JP4072867B2 (en) |
KR (1) | KR100491424B1 (en) |
CN (1) | CN1212830C (en) |
AT (3) | ATE378082T1 (en) |
AU (1) | AU712916B2 (en) |
BR (1) | BR9508688A (en) |
CA (1) | CA2198916C (en) |
DE (3) | DE69535645T2 (en) |
DK (2) | DK0778767T3 (en) |
ES (3) | ES2188669T3 (en) |
HK (1) | HK1067870A1 (en) |
PT (2) | PT1270032E (en) |
WO (1) | WO1996007397A2 (en) |
ZA (1) | ZA957356B (en) |
Cited By (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1159957A2 (en) | 1996-12-02 | 2001-12-05 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Device for the local administration of solid or semi-solid formulations, sustained release formulations for parenteral administration and process of preparation |
JP2007016049A (en) * | 1996-12-11 | 2007-01-25 | Praecis Pharmaceuticals Inc | Pharmaceutical formulations comprising water-insoluble composite for sustained drug delivery |
WO2008107467A1 (en) * | 2007-03-06 | 2008-09-12 | Novo Nordisk A/S | Pump assembly comprising actuator system |
JP2009045501A (en) * | 1998-09-18 | 2009-03-05 | Soc De Conseils De Recherches & D'applications Scientifiques (Scras) | Syringe for injecting pasty or semi-solid formulation |
US7666844B2 (en) | 1999-04-16 | 2010-02-23 | Novo Nordisk A/S | Dry mouldable drug formulation |
US8409140B2 (en) | 2007-08-17 | 2013-04-02 | Medtronic Minimed, Inc. | Injection apparatus |
US8454997B2 (en) | 2001-12-18 | 2013-06-04 | Novo Nordisk A/S | Solid dose micro implant |
US8506980B2 (en) | 2005-01-31 | 2013-08-13 | Bioserentach Co., Ltd. | Percutaneously absorbable preparation, percutaneously absorbable preparation holding sheet, and percutaneously absorbable preparation holding equipment |
EP2968695A1 (en) * | 2013-03-14 | 2016-01-20 | Allergan, Inc. | Polymer system for securing implants in syringe needles |
US9376479B2 (en) | 2002-12-31 | 2016-06-28 | Anjinomoto Althea, Inc. | Human growth hormone crystals and methods for preparing them |
US20180311168A1 (en) * | 2015-10-20 | 2018-11-01 | Enesi Pharma Limited | Solid formulation |
WO2019022951A1 (en) * | 2017-07-25 | 2019-01-31 | Amgen Inc. | Drug delivery device with gear module and related method of assembly |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
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US5837276A (en) * | 1994-09-02 | 1998-11-17 | Delab | Apparatus for the delivery of elongate solid drug compositions |
US5980945A (en) * | 1996-01-16 | 1999-11-09 | Societe De Conseils De Recherches Et D'applications Scientifique S.A. | Sustained release drug formulations |
ATE302599T1 (en) | 1996-05-24 | 2005-09-15 | Angiotech Pharm Inc | PREPARATIONS AND METHODS FOR THE TREATMENT OR PREVENTION OF DISEASES OF THE BODY PASSAGES |
SE9700423D0 (en) * | 1997-02-07 | 1997-02-07 | Astra Ab | Disposable inhalers |
GB2345010B (en) * | 1998-12-17 | 2002-12-31 | Electrosols Ltd | A delivery device |
US8465468B1 (en) * | 2000-06-29 | 2013-06-18 | Becton, Dickinson And Company | Intradermal delivery of substances |
US20020156453A1 (en) * | 1999-10-14 | 2002-10-24 | Pettis Ronald J. | Method and device for reducing therapeutic dosage |
US20020095134A1 (en) * | 1999-10-14 | 2002-07-18 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
AP2002002553A0 (en) * | 1999-12-23 | 2002-06-30 | Pfizer Prod Inc | Hydrogel-driven Drug Dosoge Form. |
US20010041869A1 (en) * | 2000-03-23 | 2001-11-15 | Causey James D. | Control tabs for infusion devices and methods of using the same |
US20040175360A1 (en) * | 2000-06-29 | 2004-09-09 | Pettis Ronald J. | Method for altering drug pharmacokinetics based on medical delivery platform |
US20050008683A1 (en) * | 2000-06-29 | 2005-01-13 | Becton Dickinson And Company | Method for delivering interferons to the intradermal compartment |
DE60127139T2 (en) * | 2000-07-14 | 2007-12-13 | Novo Nordisk A/S | METHOD FOR FORMING A PHARMACEUTICAL COMPOSITION IN A PACKAGING MATERIAL |
EP1381423A1 (en) * | 2001-04-13 | 2004-01-21 | Becton, Dickinson and Company | Methods and devices for administration of substances into the intradermal layer of skin for systemic absorption |
US20050010193A1 (en) * | 2002-05-06 | 2005-01-13 | Laurent Philippe E. | Novel methods for administration of drugs and devices useful thereof |
US20030073609A1 (en) * | 2001-06-29 | 2003-04-17 | Pinkerton Thomas C. | Enhanced pharmacokinetic profile of intradermally delivered substances |
EP1416986A4 (en) | 2001-06-29 | 2005-12-14 | Becton Dickinson Co | Intradermal delivery of vaccines and gene therapeutic agents via microcannula |
US20040120964A1 (en) * | 2001-10-29 | 2004-06-24 | Mikszta John A. | Needleless vaccination using chimeric yellow fever vaccine-vectored vaccines against heterologous flaviviruses |
US20060264886A9 (en) * | 2002-05-06 | 2006-11-23 | Pettis Ronald J | Method for altering insulin pharmacokinetics |
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US20090035260A1 (en) * | 2002-07-29 | 2009-02-05 | Therapicon Srl | Enhanced nasal composition of active peptide |
US20040082934A1 (en) * | 2002-08-30 | 2004-04-29 | Pettis Ronald J. | Method of controlling pharmacokinetics of immunomodulatory compounds |
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BRPI0414014A (en) * | 2003-08-26 | 2006-10-24 | Becton Dickinson Co | methods for intradermal delivery of therapeutic agents |
IL157981A (en) | 2003-09-17 | 2014-01-30 | Elcam Medical Agricultural Cooperative Ass Ltd | Auto-injector |
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US7896841B2 (en) * | 2004-02-17 | 2011-03-01 | Children's Hospital Medical Center | Injection device for administering a vaccine |
WO2005091922A2 (en) * | 2004-03-03 | 2005-10-06 | Becton, Dickinson And Company | Methods and devices for improving delivery of a substance to skin |
IL160891A0 (en) | 2004-03-16 | 2004-08-31 | Auto-mix needle | |
WO2005115360A2 (en) * | 2004-05-11 | 2005-12-08 | Becton, Dickinson And Company | Formulations of anti-pain agents and methods of using the same |
US9089636B2 (en) | 2004-07-02 | 2015-07-28 | Valeritas, Inc. | Methods and devices for delivering GLP-1 and uses thereof |
EP1704885A1 (en) * | 2005-03-24 | 2006-09-27 | Disetronic Licensing AG | Device for the dosed administration of a fluid product |
DE502005002757D1 (en) * | 2005-03-24 | 2008-03-20 | Disetronic Licensing Ag | Device for the dosed administration of a fluid product |
DE502005005948D1 (en) * | 2005-03-24 | 2008-12-24 | Disetronic Licensing Ag | Device for the dosed administration of a fluid product |
EP1704883B1 (en) * | 2005-03-24 | 2008-11-12 | Disetronic Licensing AG | Device for the dosed administration of a fluid product |
WO2007075839A2 (en) * | 2005-12-19 | 2007-07-05 | Diobex, Inc. | Glucagon injector for emergency treatment of hypoglycemia |
CA2641569C (en) * | 2006-02-09 | 2015-10-06 | Deka Products Limited Partnership | Fluid delivery systems and methods |
JP2009530880A (en) | 2006-03-13 | 2009-08-27 | ノボ・ノルデイスク・エー/エス | Secure pairing of electronic devices using complex communication means |
ES2566058T3 (en) | 2006-03-30 | 2016-04-08 | Valeritas, Inc. | Multi-cartridge fluid supply device |
CN101460207B (en) | 2006-06-06 | 2012-03-21 | 诺沃-诺迪斯克有限公司 | Assembly comprising skin-mountable device and packaging therefore |
US8668676B2 (en) * | 2006-06-19 | 2014-03-11 | Allergan, Inc. | Apparatus and methods for implanting particulate ocular implants |
EP2043502B1 (en) * | 2006-07-13 | 2014-03-12 | St. Jude Medical AB | Information management in devices implanted in a patient |
US20080097335A1 (en) * | 2006-08-04 | 2008-04-24 | Allergan, Inc. | Ocular implant delivery assemblies |
US8529521B2 (en) * | 2007-04-23 | 2013-09-10 | Ultimed Inc. | Low-dosage syringe |
US8986253B2 (en) | 2008-01-25 | 2015-03-24 | Tandem Diabetes Care, Inc. | Two chamber pumps and related methods |
US8408421B2 (en) | 2008-09-16 | 2013-04-02 | Tandem Diabetes Care, Inc. | Flow regulating stopcocks and related methods |
CA2737461A1 (en) | 2008-09-19 | 2010-03-25 | Tandem Diabetes Care, Inc. | Solute concentration measurement device and related methods |
US8545554B2 (en) | 2009-01-16 | 2013-10-01 | Allergan, Inc. | Intraocular injector |
US9250106B2 (en) | 2009-02-27 | 2016-02-02 | Tandem Diabetes Care, Inc. | Methods and devices for determination of flow reservoir volume |
AU2010217760B2 (en) | 2009-02-27 | 2015-04-09 | Tandem Diabetes Care, Inc. | Methods and devices for determination of flow reservoir volume |
EP2411082A1 (en) * | 2009-03-27 | 2012-02-01 | Novo Nordisk A/S | Solid dose delivery device |
EP2459251B1 (en) | 2009-07-30 | 2014-03-12 | Tandem Diabetes Care, Inc. | Infusion pump system with disposable cartridge having pressure venting and pressure feedback |
US20110251481A1 (en) * | 2009-10-15 | 2011-10-13 | Strobl Geoffrey S | Piezoelectrically-Driven Power Injector |
EP2452638A1 (en) * | 2010-11-15 | 2012-05-16 | forteq Nidau AG | Device for injecting solids |
US20130331777A1 (en) * | 2011-03-17 | 2013-12-12 | Cell Precision, LLC | Delivery devices and methods for delivering therapeutic agents |
US9180242B2 (en) | 2012-05-17 | 2015-11-10 | Tandem Diabetes Care, Inc. | Methods and devices for multiple fluid transfer |
US9173998B2 (en) | 2013-03-14 | 2015-11-03 | Tandem Diabetes Care, Inc. | System and method for detecting occlusions in an infusion pump |
US11585042B2 (en) | 2020-09-30 | 2023-02-21 | Haier Us Appliance Solutions, Inc. | Dryer appliance with additive dispenser |
GB202200706D0 (en) * | 2022-01-20 | 2022-03-09 | Cambridge Univ Hospitals Nhs Foundation Trust | A surgical instrument |
Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2239989A1 (en) * | 1973-08-08 | 1975-03-07 | Aries Robert | Pellets for subcutaneous treatment of animals - pref. implanted from a cartridge contg. several, by means of an injection force |
EP0049068A1 (en) * | 1980-09-30 | 1982-04-07 | Minnesota Mining And Manufacturing Company | Solid dose ballistic projectile |
US4451253A (en) * | 1980-12-18 | 1984-05-29 | Harman Sherman M | Means and method for administering medicinals |
EP0134318A2 (en) * | 1983-06-10 | 1985-03-20 | Connaught Laboratories Limited | Controlled release of injectable and implantable insulin compositions |
EP0230647A2 (en) * | 1985-12-27 | 1987-08-05 | Sumitomo Pharmaceuticals Company, Limited | Method for producing a sustained release formulation |
EP0403032A2 (en) * | 1987-03-16 | 1990-12-19 | Monsanto Company | Method for prolonged release of somatotropin |
WO1994022423A1 (en) * | 1993-04-07 | 1994-10-13 | Bukh Meditec A/S | Drug administration system |
WO1995022314A1 (en) * | 1994-02-18 | 1995-08-24 | Innovac Co. | Inoculation of animals with dried, pelleted biological materials |
Family Cites Families (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2513014A (en) * | 1946-11-18 | 1950-06-27 | Abbott Lab | Apparatus for implanting medicinal pellets subcutaneously |
US3995631A (en) * | 1971-01-13 | 1976-12-07 | Alza Corporation | Osmotic dispenser with means for dispensing active agent responsive to osmotic gradient |
US3760806A (en) * | 1971-01-13 | 1973-09-25 | Alza Corp | Helical osmotic dispenser with non-planar membrane |
US4177256A (en) * | 1973-04-25 | 1979-12-04 | Alza Corporation | Osmotic bursting drug delivery device |
US3995632A (en) * | 1973-05-04 | 1976-12-07 | Alza Corporation | Osmotic dispenser |
US4096238A (en) * | 1974-12-23 | 1978-06-20 | Alza Corporation | Method for administering drug to the gastrointestinal tract |
US4273122A (en) * | 1976-11-12 | 1981-06-16 | Whitney Douglass G | Self contained powered injection system |
US4086914A (en) * | 1977-02-11 | 1978-05-02 | Edwin Bailey Moore | Implant injector |
US4263910A (en) * | 1978-09-27 | 1981-04-28 | Eli Lilly And Company | Implantate package, system and method |
US4313439A (en) * | 1980-03-24 | 1982-02-02 | Biotek, Inc. | Automated, spring-powered medicament infusion system |
JPS625174Y2 (en) * | 1980-09-02 | 1987-02-05 | ||
US4327725A (en) * | 1980-11-25 | 1982-05-04 | Alza Corporation | Osmotic device with hydrogel driving member |
US4340054A (en) * | 1980-12-29 | 1982-07-20 | Alza Corporation | Dispenser for delivering fluids and solids |
US4525164A (en) * | 1981-04-24 | 1985-06-25 | Biotek, Inc. | Wearable medication infusion system with arcuated reservoir |
US4529401A (en) * | 1982-01-11 | 1985-07-16 | Cardiac Pacemakers, Inc. | Ambulatory infusion pump having programmable parameters |
DE3317536A1 (en) * | 1983-05-13 | 1984-11-15 | Siemens AG, 1000 Berlin und 8000 München | Metering device for a medicament |
US4753636A (en) * | 1983-08-02 | 1988-06-28 | Endocon, Inc. | Subcutaneous implant kit |
EP0139286B1 (en) * | 1983-10-14 | 1991-08-21 | Sumitomo Pharmaceuticals Company, Limited | Prolonged sustained-release preparations |
US4685903A (en) * | 1984-01-06 | 1987-08-11 | Pacesetter Infusion, Ltd. | External infusion pump apparatus |
US4595583A (en) * | 1984-03-19 | 1986-06-17 | Alza Corporation | Delivery system controlled administration of beneficial agent to ruminants |
GB8423749D0 (en) * | 1984-09-19 | 1984-10-24 | Sutherland I A | Powered infusion apparatus |
US4720384A (en) * | 1985-05-03 | 1988-01-19 | E. I. Du Pont De Nemours And Company | Manufacture of hollow fine tubular drug delivery systems |
US4655766A (en) * | 1985-08-01 | 1987-04-07 | Alza Corporation | Fluid imbibing pump with self-regulating skin patch |
US4661103A (en) * | 1986-03-03 | 1987-04-28 | Engineering Development Associates, Ltd. | Multiple implant injector |
US4723958A (en) * | 1986-05-23 | 1988-02-09 | Merck & Co., Inc. | Pulsatile drug delivery system |
ES2053019T3 (en) * | 1986-07-30 | 1994-07-16 | Sumitomo Pharma | SOLID PREPARATION ADMINISTRATION INSTRUMENT. |
US4693706A (en) * | 1986-08-11 | 1987-09-15 | Mark L. Anderson | Two compartment mixing syringe |
US4994028A (en) * | 1987-03-18 | 1991-02-19 | Endocon, Inc. | Injector for inplanting multiple pellet medicaments |
ES2086291T3 (en) * | 1987-05-26 | 1996-07-01 | Sumitomo Pharma | DEVICE FOR THE ADMINISTRATION OF SOLID PREPARATIONS. |
FR2618329B1 (en) * | 1987-07-22 | 1997-03-28 | Dow Corning Sa | METHOD OF MANUFACTURING A RING CAPABLE OF ENSURING THE RELEASE OF A THERAPEUTIC AGENT, AND RING MANUFACTURED BY THIS METHOD |
DE3802158A1 (en) * | 1987-08-11 | 1989-02-23 | Hoechst Ag | DEVICE FOR APPLICATION OF IMPLANTS |
US4936827A (en) * | 1988-04-11 | 1990-06-26 | Ivy Laboratories, Inc. | Implanter applicator |
US4834704A (en) * | 1988-04-13 | 1989-05-30 | Eaton Corporation | Injectable infusion pump apparatus for implanting long-term dispensing module and medication in an animal and method therefor |
US4976966A (en) * | 1988-12-29 | 1990-12-11 | Alza Corporation | Delayed release osmotically driven fluid dispenser |
US5226895A (en) * | 1989-06-05 | 1993-07-13 | Eli Lilly And Company | Multiple dose injection pen |
US5284479A (en) * | 1989-08-30 | 1994-02-08 | N.V. Nederlandsche Apparatenfabriek Nedap | Implanter |
US5086787A (en) * | 1989-12-06 | 1992-02-11 | Medtronic, Inc. | Steroid eluting intramuscular lead |
US5030216A (en) * | 1989-12-15 | 1991-07-09 | Alza Corporation | Osmotically driven syringe |
KR930001079B1 (en) * | 1990-07-18 | 1993-02-15 | 한국과학기술연구원 | Self-releasing control dosage form for insulin |
KR930008048B1 (en) * | 1991-06-05 | 1993-08-25 | 윤영우 | Interruptor without any relation with requester |
IL105553A (en) * | 1992-05-06 | 1998-01-04 | Janssen Pharmaceutica Inc | Solid dosage form comprising a porous network of matrix forming material which disperses rapidly in water |
JPH0631181A (en) * | 1992-07-06 | 1994-02-08 | Stonehard Assoc Inc | Production of highly diffused finely powdered metal carrying catalyst |
-
1994
- 1994-09-02 US US08/300,713 patent/US5582591A/en not_active Expired - Lifetime
-
1995
- 1995-06-02 US US08/460,545 patent/US5616123A/en not_active Expired - Lifetime
- 1995-08-31 EP EP20040019495 patent/EP1498150B1/en not_active Expired - Lifetime
- 1995-08-31 DE DE1995635645 patent/DE69535645T2/en not_active Expired - Lifetime
- 1995-08-31 KR KR10-2001-7005475A patent/KR100491424B1/en active IP Right Grant
- 1995-08-31 EP EP20020017692 patent/EP1270032B1/en not_active Expired - Lifetime
- 1995-08-31 EP EP95930675A patent/EP0778767B1/en not_active Expired - Lifetime
- 1995-08-31 AT AT04019495T patent/ATE378082T1/en active
- 1995-08-31 ES ES95930675T patent/ES2188669T3/en not_active Expired - Lifetime
- 1995-08-31 AU AU33981/95A patent/AU712916B2/en not_active Expired
- 1995-08-31 JP JP50935696A patent/JP4072867B2/en not_active Expired - Lifetime
- 1995-08-31 AT AT02017692T patent/ATE280599T1/en active
- 1995-08-31 PT PT02017692T patent/PT1270032E/en unknown
- 1995-08-31 WO PCT/IB1995/000778 patent/WO1996007397A2/en active IP Right Grant
- 1995-08-31 AT AT95930675T patent/ATE230977T1/en active
- 1995-08-31 ES ES02017692T patent/ES2230431T3/en not_active Expired - Lifetime
- 1995-08-31 DE DE1995633709 patent/DE69533709T2/en not_active Expired - Lifetime
- 1995-08-31 PT PT04019495T patent/PT1498150E/en unknown
- 1995-08-31 CN CNB951954725A patent/CN1212830C/en not_active Expired - Lifetime
- 1995-08-31 BR BR9508688A patent/BR9508688A/en not_active Application Discontinuation
- 1995-08-31 ES ES04019495T patent/ES2295745T3/en not_active Expired - Lifetime
- 1995-08-31 DK DK95930675T patent/DK0778767T3/en active
- 1995-08-31 CA CA 2198916 patent/CA2198916C/en not_active Expired - Lifetime
- 1995-08-31 DK DK02017692T patent/DK1270032T3/en active
- 1995-08-31 DE DE1995629415 patent/DE69529415T2/en not_active Expired - Lifetime
- 1995-09-01 ZA ZA957356A patent/ZA957356B/en unknown
-
2005
- 2005-02-16 HK HK05101305A patent/HK1067870A1/en not_active IP Right Cessation
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2239989A1 (en) * | 1973-08-08 | 1975-03-07 | Aries Robert | Pellets for subcutaneous treatment of animals - pref. implanted from a cartridge contg. several, by means of an injection force |
EP0049068A1 (en) * | 1980-09-30 | 1982-04-07 | Minnesota Mining And Manufacturing Company | Solid dose ballistic projectile |
US4451253A (en) * | 1980-12-18 | 1984-05-29 | Harman Sherman M | Means and method for administering medicinals |
EP0134318A2 (en) * | 1983-06-10 | 1985-03-20 | Connaught Laboratories Limited | Controlled release of injectable and implantable insulin compositions |
EP0230647A2 (en) * | 1985-12-27 | 1987-08-05 | Sumitomo Pharmaceuticals Company, Limited | Method for producing a sustained release formulation |
EP0403032A2 (en) * | 1987-03-16 | 1990-12-19 | Monsanto Company | Method for prolonged release of somatotropin |
WO1994022423A1 (en) * | 1993-04-07 | 1994-10-13 | Bukh Meditec A/S | Drug administration system |
WO1995022314A1 (en) * | 1994-02-18 | 1995-08-24 | Innovac Co. | Inoculation of animals with dried, pelleted biological materials |
Non-Patent Citations (1)
Title |
---|
DATABASE WPI Section Ch, Week 9242, Derwent Publications Ltd., London, GB; Class B04, AN 92-124827 & JP,A,4 244 031 ( ZH KANKOKU KAGAKU GIJUTSU KENK) 1 September 1992 * |
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EP1159957A2 (en) | 1996-12-02 | 2001-12-05 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Device for the local administration of solid or semi-solid formulations, sustained release formulations for parenteral administration and process of preparation |
JP2007016049A (en) * | 1996-12-11 | 2007-01-25 | Praecis Pharmaceuticals Inc | Pharmaceutical formulations comprising water-insoluble composite for sustained drug delivery |
JP2011105760A (en) * | 1996-12-11 | 2011-06-02 | Praecis Pharmaceuticals Inc | Pharmaceutical formulation containing water-insoluble complex for sustained drug delivery |
JP2009045501A (en) * | 1998-09-18 | 2009-03-05 | Soc De Conseils De Recherches & D'applications Scientifiques (Scras) | Syringe for injecting pasty or semi-solid formulation |
US8518430B2 (en) | 1999-04-16 | 2013-08-27 | Novo Nordisk A/S | Dry mouldable drug formulation |
US7666844B2 (en) | 1999-04-16 | 2010-02-23 | Novo Nordisk A/S | Dry mouldable drug formulation |
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US9376479B2 (en) | 2002-12-31 | 2016-06-28 | Anjinomoto Althea, Inc. | Human growth hormone crystals and methods for preparing them |
US8506980B2 (en) | 2005-01-31 | 2013-08-13 | Bioserentach Co., Ltd. | Percutaneously absorbable preparation, percutaneously absorbable preparation holding sheet, and percutaneously absorbable preparation holding equipment |
WO2008107467A1 (en) * | 2007-03-06 | 2008-09-12 | Novo Nordisk A/S | Pump assembly comprising actuator system |
US8409140B2 (en) | 2007-08-17 | 2013-04-02 | Medtronic Minimed, Inc. | Injection apparatus |
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EP3632482A1 (en) * | 2013-03-14 | 2020-04-08 | Allergan, Inc. | Polymer system for securing implants in syringe needles |
US20180311168A1 (en) * | 2015-10-20 | 2018-11-01 | Enesi Pharma Limited | Solid formulation |
US11135170B2 (en) | 2015-10-20 | 2021-10-05 | Enesi Pharma Limited | Solid formulation |
WO2019022951A1 (en) * | 2017-07-25 | 2019-01-31 | Amgen Inc. | Drug delivery device with gear module and related method of assembly |
US11617837B2 (en) | 2017-07-25 | 2023-04-04 | Amgen Inc. | Drug delivery device with gear module and related method of assembly |
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