WO1996000592A3 - Biodegradable fracture fixation plates and uses thereof - Google Patents
Biodegradable fracture fixation plates and uses thereof Download PDFInfo
- Publication number
- WO1996000592A3 WO1996000592A3 PCT/US1995/008171 US9508171W WO9600592A3 WO 1996000592 A3 WO1996000592 A3 WO 1996000592A3 US 9508171 W US9508171 W US 9508171W WO 9600592 A3 WO9600592 A3 WO 9600592A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- prosthetic devices
- biodegradable
- fixation plates
- pharmacologically active
- reinforced
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/121—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/121—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix
- A61L31/123—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having an inorganic matrix of phosphorus-containing materials, e.g. apatite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/12—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material
- A61L31/125—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix
- A61L31/129—Composite materials, i.e. containing one material dispersed in a matrix of the same or different material having a macromolecular matrix containing macromolecular fillers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/148—Materials at least partially resorbable by the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
- A61L2300/414—Growth factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/60—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
- A61L2300/602—Type of release, e.g. controlled, sustained, slow
- A61L2300/604—Biodegradation
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Surgery (AREA)
- Vascular Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Composite Materials (AREA)
- Materials Engineering (AREA)
- Inorganic Chemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Materials For Medical Uses (AREA)
Abstract
The present invention provides materials for use in biodegradable structural prosthetic devices with enhanced load-bearing strength and reinforced flexibility. Prosthetic devices are also provided, which comprise a biodegradable polymer layer, reinforced by a biodegradable material, and optionally, the inclusion of pharmacologically active substances, such as growth factors and anti-microbial agents. The prosthetic devices provide for gradually decreasing structural support that lessens as the implant degrades and is compensated by new bone growth. The degradation also provides for the controlled release of the pharmacologically active agents. The prosthetic devices are exemplified by bone fixation plates.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU29521/95A AU2952195A (en) | 1994-06-28 | 1995-06-28 | Biodegradable fracture fixation plates and uses thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26731994A | 1994-06-28 | 1994-06-28 | |
US08/267,319 | 1994-06-28 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1996000592A2 WO1996000592A2 (en) | 1996-01-11 |
WO1996000592A3 true WO1996000592A3 (en) | 1996-02-22 |
Family
ID=23018279
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1995/008171 WO1996000592A2 (en) | 1994-06-28 | 1995-06-28 | Biodegradable fracture fixation plates and uses thereof |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2952195A (en) |
WO (1) | WO1996000592A2 (en) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998046289A1 (en) * | 1997-04-16 | 1998-10-22 | White Spot Ag | Biodegradable osteosynthesis implant |
US7541049B1 (en) | 1997-09-02 | 2009-06-02 | Linvatec Biomaterials Oy | Bioactive and biodegradable composites of polymers and ceramics or glasses and method to manufacture such composites |
ES2187195T3 (en) | 1998-09-11 | 2003-05-16 | Gerhard Dr Schmidmaier | BIOLOGICALLY ACTIVE IMPLANTS. |
US6398814B1 (en) | 1998-09-14 | 2002-06-04 | Bionx Implants Oy | Bioabsorbable two-dimensional multi-layer composite device and a method of manufacturing same |
US6350284B1 (en) | 1998-09-14 | 2002-02-26 | Bionx Implants, Oy | Bioabsorbable, layered composite material for guided bone tissue regeneration |
WO2000054821A1 (en) * | 1999-03-16 | 2000-09-21 | Regeneration Technologies, Inc. | Molded implants for orthopedic applications |
US8016865B2 (en) | 2003-09-29 | 2011-09-13 | Depuy Mitek, Inc. | Method of performing anterior cruciate ligament reconstruction using biodegradable interference screw |
US8641738B1 (en) | 2004-10-28 | 2014-02-04 | James W. Ogilvie | Method of treating scoliosis using a biological implant |
US8123787B2 (en) | 2004-10-28 | 2012-02-28 | Ogilvie James W | Method of treating scoliosis using a biological implant |
MD2856G2 (en) * | 2005-03-29 | 2006-04-30 | Валериу ФАЛА | Material for osteoplasty (variants) |
MD2877G2 (en) * | 2005-04-05 | 2006-05-31 | Валериу ФАЛА | Material for osteoplasty (variants) |
FI20055194A (en) * | 2005-04-27 | 2006-10-28 | Bioretec Oy | Bioabsorbent and bioactive composite material and process for manufacturing composite |
WO2017041109A1 (en) * | 2015-09-03 | 2017-03-09 | Case Western Reserve University | Polymer fiber scaffolds and uses thereof |
US20210146016A1 (en) | 2019-11-15 | 2021-05-20 | Evonik Operations Gmbh | Fiber reinforced compositions and methods of manufacture for medical device applications |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4279249A (en) * | 1978-10-20 | 1981-07-21 | Agence Nationale De Valorisation De La Recherche (Anvar) | New prosthesis parts, their preparation and their application |
EP0194192A1 (en) * | 1985-02-22 | 1986-09-10 | Ethnor | Absorbable composite chirurgical material, method of preparation, resorbable prosthesis based on this material and use of this prosthesis |
WO1990004982A1 (en) * | 1988-11-10 | 1990-05-17 | Biocon Oy | Biodegradable surgical implants and devices |
WO1990013302A1 (en) * | 1989-04-28 | 1990-11-15 | Brigham And Women's Hospital | Novel materials and methods for guided tissue regeneration |
EP0550875A1 (en) * | 1991-12-31 | 1993-07-14 | Schierholz, Jörg, Dr.Dr. | Implantable polymeric device containing pharmaceutical agents and process for its production |
US5281419A (en) * | 1992-09-28 | 1994-01-25 | Thomas Jefferson University | Biodegradable drug delivery system for the prevention and treatment of osteomyelitis |
EP0636377A1 (en) * | 1993-07-28 | 1995-02-01 | JOHNSON & JOHNSON MEDICAL, INC. | Composite surgical material |
-
1995
- 1995-06-28 AU AU29521/95A patent/AU2952195A/en not_active Abandoned
- 1995-06-28 WO PCT/US1995/008171 patent/WO1996000592A2/en active Application Filing
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4279249A (en) * | 1978-10-20 | 1981-07-21 | Agence Nationale De Valorisation De La Recherche (Anvar) | New prosthesis parts, their preparation and their application |
EP0194192A1 (en) * | 1985-02-22 | 1986-09-10 | Ethnor | Absorbable composite chirurgical material, method of preparation, resorbable prosthesis based on this material and use of this prosthesis |
WO1990004982A1 (en) * | 1988-11-10 | 1990-05-17 | Biocon Oy | Biodegradable surgical implants and devices |
WO1990013302A1 (en) * | 1989-04-28 | 1990-11-15 | Brigham And Women's Hospital | Novel materials and methods for guided tissue regeneration |
EP0550875A1 (en) * | 1991-12-31 | 1993-07-14 | Schierholz, Jörg, Dr.Dr. | Implantable polymeric device containing pharmaceutical agents and process for its production |
US5281419A (en) * | 1992-09-28 | 1994-01-25 | Thomas Jefferson University | Biodegradable drug delivery system for the prevention and treatment of osteomyelitis |
EP0636377A1 (en) * | 1993-07-28 | 1995-02-01 | JOHNSON & JOHNSON MEDICAL, INC. | Composite surgical material |
Also Published As
Publication number | Publication date |
---|---|
AU2952195A (en) | 1996-01-25 |
WO1996000592A2 (en) | 1996-01-11 |
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