WO1995021645B1 - Self administered injection pen apparatus and method - Google Patents

Self administered injection pen apparatus and method

Info

Publication number
WO1995021645B1
WO1995021645B1 PCT/US1995/001509 US9501509W WO9521645B1 WO 1995021645 B1 WO1995021645 B1 WO 1995021645B1 US 9501509 W US9501509 W US 9501509W WO 9521645 B1 WO9521645 B1 WO 9521645B1
Authority
WO
WIPO (PCT)
Prior art keywords
assembly
medicament
injection apparatus
medicament injection
tubular
Prior art date
Application number
PCT/US1995/001509
Other languages
French (fr)
Other versions
WO1995021645A1 (en
Filing date
Publication date
Priority claimed from US08/195,307 external-priority patent/US5514097A/en
Application filed filed Critical
Priority to AT95909492T priority Critical patent/ATE205097T1/en
Priority to DE69522551T priority patent/DE69522551T2/en
Priority to JP52128195A priority patent/JP3686083B2/en
Priority to EP95909492A priority patent/EP0744975B1/en
Priority to DK95909492T priority patent/DK0744975T3/en
Priority to CA002181802A priority patent/CA2181802C/en
Publication of WO1995021645A1 publication Critical patent/WO1995021645A1/en
Publication of WO1995021645B1 publication Critical patent/WO1995021645B1/en

Links

Abstract

A medicament injection apparatus for subcutaneous or intramuscular delivery of a medicament conceals the needle behind a needle shroud. On apparatus activation, the needle is trust forward, pushing the needle tip outside the needle shroud with enough force to puncture the skin. The needle is thus automatically introduced into the tissue at the proper needle/skin orientation. In the same action, the apparatus automatically dispenses an accurate pre-set dose. The dose can be set by a manual, variable dosing assembly or by an automatic dosing assembly. The automatic dosing assembly includes a safety mechanism preventing the pre-set dose from being changed except by a doctor or patient using a special wrench or tool.

Claims

AMENDED CLAIMS
[received by the International Bureau on 11 August 1995 (11.08.95); original claims 1, 2, 10, 17, 19-22, 24, 31, 33-38, 55 amended;
new claims 58-63 added; remaining claims unchanged (23 pages)] 1. A medicament injection apparatus comprising: a housing having:
an exterior surface, and enclosing an interior volume;
a first end; and
a second end opposite said first end; a needle shroud removably affixed to said first end of said housing and having an open end removed from said housing;
a medicament injection assembly, movably mounted in said interior volume of said housing, including:
an automatic dosing assembly including an automatic does knob having a stop position,
wherein upon moving said automatic dose knob to said stop position said automatic dose assembly is set for a predetermined dose; and
upon engagement and activation of a motive force supplied by said
automatic dosing assembly, a plurality of assemblies of said medicament injection assembly move from a first position to a second position in a first direction wherein said first direction is towards said open end of said needle shroud.
2. The medicament injection apparatus of
Claim 1, wherein said medicament injection assembly further comprises:
an automatic dosing assembly mounted in said interior volume of said housing wherein upon engagement and actuation of said medicament injection assembly, said automatic dosing assembly applies said motive force to said plurality of assemblies of said medicament injection assembly thereby moving said plurality of assemblies from said first position to said second position,
3. The medicament injection apparatus of
Claim 2, wherein one of said plurality of assemblies of said medicament injection assembly comprises:
a variable dosing assembly movably coupled to said automatic dosing assembly, and having a first end wherein;
said variable dosing assembly is selectively engaged by said user to dispense a predetermined and adjustable amount of a medicament from said medicament injection apparatus upon engagement and actuation of said medicament injection assembly.
4. The medicament injection apparatus of
Claim 3, wherein another one of said plurality of assemblies of said medicament injection assembly comprises:
a medicament cartridge assembly removably affixed to said first end of said variable dosing assembly, and including a first end and a second end opposite said first end wherein said second end is fashioned to accept a medicament cartridge having a first sealed end and a second end opposite said first sealed end which contains a movable plunger.
5. The medicament injection apparatus of
Claim 4, wherein said medicament cartridge assembly further comprises: a needle subassembly removably affixed to said first end of said medicament cartridge assembly, and having a needle;
wherein when said needle subassembly is in said first position, said needle is contained within said needle shroud; and
when said needle subassembly is in said second position, said needle has an end extending through said open end of said needle shroud.
6. The medicament injection apparatus of
Claim 5, further comprising:
a needle safety cap removably affixed to said medicament cartridge assembly wherein said needle safety cap encloses said needle.
7 . The medicament injection apparatus of
Claim 4, wherein said variable dosing assembly further comprises:
a pushrod subassembly including a pushrod wherein upon engagement and actuation of said automatic dosing assembly, said pushrod engages said plunger and moves said plunger in said first direction inside said medicament cartridge; and a dosing sleeve subassembly movably mounted on said pushrod, wherein said dosing sleeve subassembly position on said pushrod determines a distance said pushrod moves in said first
direction.
8. The medicament injection apparatus of
Claim 2, wherein said automatic dosing assembly further comprises: a thrusting assembly having a motive force subassembly chat is selectively engaged and actuated by a user;
wherein upon engagement and actuation of said motive force subassembly, said thrusting assembly moves said plurality of assemblies of said medicament injection assembly from said first position to said second position.
9. The medicament injection apparatus of
Claim 8, wherein said thrusting assembly further comprises:
a tubular dose knob selectively engagable with a variable dosing assembly of said medicament injection assembly, and having a first open end and a second end opposite to said first open end;
wherein upon engagement of said tubular dose knob with said variable dosing assembly and movement of said tubular dose knob in a selected direction, said user adjusts an amount of a medicament to be dispensed from said medicament injection apparatus.
10. The medicament injection apparatus of
Claim 9, wherein said automatic dosing assembly further comprises:
a dose knob stop subassembly coupled to said tubular dose knob wherein said dose knob stop assembly limits movement of said tubular dose knob in said selected direction and so limits said amount of said medicament to be dispensed from said medicament injection apparatus to a
predetermined and pre-set limit.
11. The medicament injection apparatus of
Claim 20, wherein said does knob stop assembly further comprises:
two structures coupled to said tubular dose knob and each of said two structures having a surface wherein said two structures are mounted within said automatic dosing assembly so that said surfaces interact and interface with one another such that a combined length of the two structures ie variable depending on a relative position of said two surfaces and further wherein said variable combined length determines said
predetermined and pre-set limit.
12. The medicament injection apparatus of
Claim 11, wherein said dose knob stop subassembly further comprises:
a dose limiting sleeve coupled to at least one of said two structures and selectively engaged by said user to adjust said relative position of said surfaces of said two structures to set said predetermined and pre-set limit.
13. The medicament injection apparatus of
Claim 12, wherein said dose limiting sleeve comprises a tubular structure having a first end and a second end opposite said first open end wherein one of said two structures is positioned within said first open end of tubular structure,
14. The medicament injection apparatus of
Claim 13, wherein said one of said two structures includes a set of grooves and said dose limiting sleeve tubular structure includes a set of rails and further wherein said sets of grooves and rails rotationally couple said one of said two structures and said dose limiting sleeve tubular structure so chat said one of said two structures and said dose limiting sleeve tubular structure rotate together.
15. The medicament injection apparatus of
Claim 11, wherein said two structures comprise angled cylinders.
16. The medicament injection apparatus of
Claim 11, wherein said two structures comprise stepped angled cylinders.
17. The medicament injection apparatus of
Claim 9, wherein said medicament injection assembly further comprises:
a runner having a first tubular portion and a second tubular portion wherein said first tubular portion has a first open end and a second open end opposite said first open end, and further wherein said second open end of said first tubular portion is coupled to a first open end of said second tubular portion and said second tubular portion has a second open end opposite said first end.
18. The medicament injection apparatus of
Claim 17, wherein said variable dosing assembly further comprises;
a dosing sleeve subassembly partially
positioned within said first open end of said first tubular portion of said runner such that said dosing sleeve subassembly can move back and forth in both said first direction and said second direction within said first tubular portion of said runner;
wherein said second tubular portion of said runner has a smaller cross-section than a cross-section of said first open end of said tubular dose knob so that at least part of said second tubular portion of said runner is positioned inside said first open end of said tubular dose knob and said second tubular portion can move back and forth in both said first direction and said second direction within said tubular dose knob.
19. The medicament injection apparatus of
Claim 18, wherein said second tubular portion of said runner includes a set of grooves and said tubular dose knob includes a set of rails and further wherein said sets of grooves and rails rotationally couple said runner and said tubular dose knob so that said runner and said tubular dose knob rotate together to move said dosing sleeve subassembly back and forth in both said first direction and said second direction within said first tubular portion of said runner and adjust an amount of medicament dispensed from said medicament injection apparatus.
20. The medicament injection apparatus of
Claim 19, wherein:
a pushrod of said variable dosing assembly has a first end and a second end opposite said first end wherein said second end of said pushrod is positioned within said first open end of said second tubular portion of said runner; and
said second end of said tubular dose knob is closed; and further wherein
said second tubular portion of said runner with said pushrod positioned within said first open end of said second tubular portion and said tubular dose knob form an enclosed cavity with a variable length which is smaller when said plurality of assemblies of said medicament injection assembly are in said first position and larger when said plurality of assemblies are in said second position; and
said motive force subassembly is positioned inside said cavity such that said motive force subassembly exerts a force on said second end of pushrod in said first direction and said motive force subassembly exerts a force on said tubular dose knob in said second direction when said plurality of assemblies are in said first
position.
21. The medicament injection apparatus of
Claim 20, wherein said pushrod and said runner are coupled so that:
when said plurality of assemblies are in said first position said pushrod and said runner are removably affixed; and
when said plurality of assemblies move from said first position to said second position said pushrod and said runner remain removably affixed for a predetermined distance; and
said pushrod is uncoupled from said runner once said pushrod and said runner have moved together said predetermined distance.
22. The medicament injection apparatus of
Claim 21, wherein said thrusting assembly further comprises:
a lock ring selectively engaging and holding said tubular dose knob against said force exerted in said second direction; and a needle thrust locking mechanism selectively engaging and holding said runner and said pushrod against said force exerted in said first
direction.
23. The medicament injection apparatus of
Claim 22, wherein said motive force subassembly comprises a spring and a thrust bearing.
24 The medicament injection apparatus of
Claim 1, wherein said medicament injection assembly further comprises:
a thrusting assembly having a motive force subassembly that is selectively engaged and actuated by a user;
wherein upon engagement and actuation of said motive force subassembly, said thrusting assembly moves said plurality of assemblies of said medicament injection assembly from said first position to said second position.
25. The medicament injection apparatus of
Claim 24, wherein one of said plurality of assemblies of said medicament injection assembly further
comprises:
a variable dosing assembly movably coupled to said thrusting assembly, and having a first end wherein;
said variable dosing assembly is selectively engaged by said user to dispense a predetermined and adjustable amount of a medicament from said medicament injection apparatus upon engagement and actuation of said medicament injection assembly.
26. The medicament injection apparatus of
Claim 25, wherein another one of said plurality of assemblies of said medicament injection assembly further comprises:
a medicament cartridge assembly removably affixed to said first end of said variable dosing assembly, and including a first end and a second end opposite said first end wherein said second end is fashioned to accept a medicament cartridge having a first sealed end and a second end opposite said first sealed end which contains a movable plunger.
27. The medicament injection apparatus of
Claim 25, wherein said medicament cartridge assembly further comprises;
a needle subassembly removably affixed to said first end of said medicament cartridge assembly, and having a needle;
wherein when said needle subassembly is in said first position, said needle is contained within said needle shroud; and
when said needle subassembly is in said second position, said needle has an end extending through said open end of said needle shroud.
28. The medicament injection apparatus of
Claim 27, further comprising:
a needle safety cap removably affixed to said medicament cartridge assembly wherein said needle safety cap encloses said needle.
29. The medicament injection apparatus of
Claim 26, wherein said variable dosing assembly further comprises: a pushrod subassembly including a pushrod wherein upon engagement and actuation of said thrusting assembly, said pushrod engages said plunger and moves said plunger in said first direction inside said medicament cartridge; and a dosing sleeve subassembly movably mounted on said pushrod, wherein said dosing sleeve subassembly position on said pushrod determines a distance said pushrod moves in said first
direction.
30. The medicament injection apparatus of
Claim 26, wherein said thrusting assembly further comprises;
a tubular dose knob selectively engagable with said variable dosing assembly of said medicament injection assembly, and having a first open end and a second end opposite to said first open end;
wherein upon engagement of said tubular dose knob with said variable dosing assembly and movement of said tubular dose knob in a selected direction, said user adjusts an amount of a medicament to be dispensed from said medicament injection apparatus.
31. The medicament injection apparatus of
Claim 26, wherein said medicament injection assembly further comprises:
a runner having a first tubular portion and a second tubular portion wherein said first tubular portion has a first open end and a second open end opposite said first open end, and further wherein said second open end of said first tubular portion is coupled to a first open end of said second tubular poreion and said second tubular portion has a second open end opposite said first end.
32. The medicament injection apparatus of
Claim 31, wherein said variable dosing assembly further comprises:
a dosing sleeve subassembly partially
positioned within said first open end of said first tubular portion of said runner such that said dosing sleeve subassembly can move back and forth in both eaid first direction and said second direction within said first tubular portion of said runner;
wherein said second tubular portion of said runner has a smaller cross-section than a cross-section of said first open end of said tubular dose knob so that at least part of said second tubular portion of said runner is positioned inside said first open end of said tubular dose knob and said second tubular portion can move back and forth in both said first direction and said second direction within said tubular dose knob.
33. The medicament injection apparatus of
Claim 32, wherein said second tubular portion of said runner includes a set of grooves and said cubular dose knob includes a set of rails and further wherein said sets of grooves and rails rotationally couple said runner and said tubular dose knob so that said runner and said tubular dose knob rotate together to move said dosing sleeve subassembly back and forth in both said first direction and said second direction within said first tubular portion of said runner and adjust an amount of medicament dispensed from said medicament injection apparatus,
34. The medicament injection apparatus of
Claim 33, wherein:
said pushrod has a first end and a second end opposite said first end wherein said second end of said pushrod is positioned within said first open end of said second tubular portion of said runner; and
said second end of said tubular dose knob is closed; and further wherein
said second tubular portion of said runner with said pushrod positioned within said first open end of said second tubular portion and said tubular dose knob form an enclosed cavity with a variable length which is smaller when said plurality of assemblies of said medicament injection assembly are in said first position and larger when said plurality of assemblies are in said second position; and
said motive force subassembly is positioned inside said cavity such that said motive force subassembly exerts a force on said second end of pushrod in said first direction and said motive force subassembly exerts a force on said tubular dose knob in said second direction when said plurality of assemblies are in said first
position.
35. The medicament injection apparatus of
Claim 34, wherein:
said pushrod and said runner are coupled so that:
when said plurality of assemblies are in said first position said pushrod and said runner are removably affixed; and when said plurality of assemblies move from said first position to said second position said pushrod and said runner remain removably affixed for a predetermined distance; and
said pushrod is uncoupled from said runner once said pushrod and said runner have moved together said predetermined distance.
36. The medicament injection apparatus of
Claim 35, wherein said thrusting assembly further comprises:
a lock ring selectively engaging and holding said tubular dose knob against said force exerted in said second direction; and
a needle thrust locking mechanism selectively engaging and holding said runner and said pushrod against said force exerted in said first
direction.
37. The medicament injection apparatus of
Claim 36, wherein said motive force subassembly
comprises a spring and a thrust bearing.
38. A medicament injection apparatus comprising: a housing having:
an exterior surface and enclosing an interior volume;
a first end; and
a second end opposite said first end; a needle shroud removably affixed to said first end of said housing and having an open end removed from said housing;
a medicament cartridge assembly movably.
mounted in said interior volume of said housing so that upon application of a motive force, said medicament cartridge assembly moves from a first position to a second position in a first direction wherein said first direction is towards said open end of said needle shroud, and further wherein said medicant cartridge includes:
a first end;
a second end opposite said first end wherein said second end is fashioned to accept a medicament cartridge having a first sealed end and a second end opposite said first sealed end which contains a movable plunger; and
a variable dosing assembly having a first end removably affixed to said second end of said medicament cartridge assembly and a second end wherein;
said variable dosing assembly is selectively engaged by said user to control a predetermined and adjustable amount of medicament expelled from said medicament cartridge following application of said motive force; and
an automatic dosing assembly removably affixed to said second end of said variable dosing assembly and mounted in said interior volume of said housing, said automatic dosing assembly including an automatic dose knob having a stop position;
wherein upon moving said automatic dose knob to said stop position said automatic dose assembly is set for a predetermined dose; and
upon engagement and actuation of said automatic dosing assembly, said automatic dosing assembly supplies said motive force to said variable dosing assembly and said medicament cartridge assembly thereby moving said variable dosing assembly and said medicament cartridge assembly from said first position to said second position.
39. The medicament injection apparatus of
Claim 38, further comprising:
a needle subassembly removably affixed to said first end of said medicament cartridge assembly, and having a needle;
wherein when said medicament cartridge assembly is in said first position, said needle is contained within said needle shroud; and
when said medicament cartridge assembly is in eaid second position said needle has an end extending through said open end of said needle shroud.
40. The medicament injection apparatus of
Claim 39, further comprising:
a needle safety cap removably affixed to said medicament cartridge assembly wherein said needle safety cap encloses said needle.
41. The medicament injection apparatus of
Claim 38, wherein said variable dosing assembly further comprises:
a pushrod subassembly including a pushrod wherein upon engagement and actuation of said automatic dosing assembly, said pushrod engages said plunger and moves said plunger in said first direction inside said medicament cartridge; and a dosing sleeve subassembly movably mounted on said pushrod, wherein said dosing sleeve subassembly position on said pushrod determines a distance said pushrod moves in said first
direction.
42. The medicament injection apparatus of
Claim 38, wherein said automatic dosing assembly further comprises:
a thrusting assembly having a motive force subassembly that is selectively engaged and actuated by a user;
wherein upon engagement and actuation of said motive force subassembly, said thrusting assembly moves said variable dosing assembly and said medicament cartridge assembly from said first position to said second position.
43. The medicament injection apparatus of
Claim 42, wherein said thrusting assembly further comprises:
a tubular dose knob selectively engagable with said variable dosing assembly and having a first open end and a second end opposite to said first open end;
wherein upon engagement of said tubular dose knob with said variable dosing assembly and movement of said tubular dose knob in a selected direction, said user adjusts an amount of a medicament to be dispensed from said medicament injection apparatus.
44. The medicament injection apparatus of
Claim 43, wherein said automatic dosing assembly further comprises:
a dose knob stop subassembly coupled to said tubular dose knob wherein said dose knob stop assembly limits movement of said tubular dose knob in said selected direction and 30 limits said amount of said medicament to be dispensed from said medicament injection apparatus to a
predetermined and pre-set limit.
45. The medicament injection apparatus of
Claim 44, wherein said dose knob stop assembly further comprises:
two structures coupled to said tubular dose knob and each of said two structures having a surface wherein said two structures are mounted within said automatic dosing assembly so that said surfaces interact and interface with one another such that a combined length of the two structures is variable depending on a relative position of said two surfaces and further wherein said variable combined length determines said
predetermined and pre-set limit.
46. The medicament injection apparatus of
Claim 45, wherein said dose knob stop subassembly further comprises:
a dose limiting sleeve coupled to at least one of said two structures and selectively engaged by said user to adjust said relative position of said surfaces of said two structures to set said
predetermined and pre-set limit.
47. The medicament injection apparatus of
Claim 46, wherein said dose limiting sleeve comprises a tubular structure having a first open end and a second end opposite said first open end wherein one of said two structures is positioned within said first open end of tubular structure.
48. The medicament injection apparatus of
Claim 47, wherein said one of said two structures includes a set of grooves and said dose limiting sleeve tubular structure includes a set of rails and further wherein seta of grooves and rails rotationally couple said one of said two structures and said dose limiting sleeve tubular structure so that said one of said two structures and said dose limiting sleeve tubular structure rotate together.
49. The medicament injection apparatus of
Claim 48, wherein said two structures comprise angled cylinders.
50. The medicament injection apparatus of
Claim 48, wherein said two structures comprise stepped angled cylinders.
51. The medicament injection apparatus of
Claim 48, wherein said medicament injection apparatus further comprises:
a runner having a first tubular portion and a second tubular portion wherein said first tubular portion has a first open end and a second open end opposite said first open end, and further wherein said second open end of said first tubular portion is coupled to a first open end of said second tubular portion and said second tubular portion has a second open end opposite said first end.
52. The medicament injection apparatus of
Claim 51, wherein said variable dosing assembly further comprises:
a dosing sleeve subassembly partially positioned within said first open end of said first tubular portion of said runner such that said dosing sleeve subassembly can move back and forth in both said first direction and said second direction within said first tubular portion of said runner;
wherein said second tubular portion of said runner has a smaller cross-section than a cross-section of said first open end of said tubular dose knob so that at least part of said second tubular portion of said runner is positioned inside said first open end of said tubular dose knob and said second tubular portion can move back and forth in both said first direction and said second direction within said tubular dose knob.
53. The medicament injection apparatus of
Claim 52, wherein said second tubular portion of said runner includes a set of grooves and said tubular dose knob includes a set of rails and further wherein said sets of grooves and rails rotationally couple said runner and said tubular dose knob so that said runner and said tubular dose knob rotate together to move said dosing sleeve subassembly back and forth in both said first direction and said second direction within said first tubular portion of said runner and adjust an amount of medicament dispensed from said medicament injection apparatus.
54. The medicament injection apparatus of
Claim 53, wherein:
said pushrod has a first end and a second end opposite said first end wherein said second and of said pushrod is positioned within said first open end of said second tubular portion of said runner; and said second end of said tubular dose knob is closed; and further wherein
said second tubular portion of said runner with said pushrod positioned within said first open end of said second tubular portion and said tubular dose knob form an enclosed cavity with a variable length which is smaller when said variable dosing assembly and said medicament cartridge assembly are in said first position and larger when said variable dosing assembly and said medicament cartridge assembly are in said second position; and
said motive force subassembly is positioned inside said cavity such that said motive force subassembly exerts a force on said second end of pushrod in said first direction and said motive force subassembly exerts a force on said tubular dose knob in said second direction when said variable dosing assembly and said medicament cartridge assembly are in said first position.
55. The medicament injection apparatus of
Claim 54, wherein said pushrod and said runner are coupled so that:
when said variable dosing assembly and said medicament cartridge assembly are in said first position said pushrod and said runner are
removably affixed; and
when said variable dosing assembly and said medicament cartridge assembly move from said first position to said second position said pushrod and said runner remain removably affixed for a predetermined distance; and said pushrod is uncoupled from said runner once said pushrod and said runner have moved together said predetermined distance.
56. The medicament injection apparatus of
Claim 55, wherein said thrusting assembly further comprises:
a lock ring selectively engaging and holding said tubular dose knob against said force exerted in said second direction; and
a needle thrust locking mechanism selectively engaging and holding said runner and said pushrod against said force exerted in said first
direction.
57. The medicament injection apparatus of
Claim 56, wherein said motive force subassembly
comprises a spring and a thrust bearing.
58. The medicament injection apparatus as in Claim 1, wherein
said needle shroud is removably affixed to said first end of said housing by a friction fit.
59. A medicament injection apparatus as in
Claim 58, wherein
said open end of said needle shroud is removed a first distance from said first end of said housing.
60. The medicament injection apparatus as in Claim 59, further comprising;
another needle shroud, wherein upon removal of said needle shroud and removably affixing said another needle shroud to said first end of said housing, an open end of said another needle shroud is removed a second distance, different from said first distance, from said first end of said housing.
61. A medicament injection apparatus as in
Claim 58, further comprising:
at least two needle shrouds in addition to said needle shroud;
wherein each of said at least two needle shrouds can be individually removably affixed to said first end of said housing;
upon individually removably affixing said at least two needle shrouds to said first end of said housing, each of said at least two needle shrouds have an open end removed a predetermined distance from said first end of said housing; and
said predetermined distance is different for each of said at least two needle shrouds.
62. A medicament injection apparatus as in
Claim 38, wherein
said open end of said needle shroud is removed a first distance from said first end of housing.
63. The medicament injection apparatus as in Claim 62, further comprising:
another needle shroud, wherein upon removal of said needle shroud and removably affixing said another needle shroud to said first end of said housing, said open end of said another needle shroud is removed a second distance, different from said first distance, from said first end of said housing.
PCT/US1995/001509 1994-02-14 1995-02-14 Self administered injection pen apparatus and method WO1995021645A1 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
AT95909492T ATE205097T1 (en) 1994-02-14 1995-02-14 DEVICE FOR SELF-ADMINISTRATION OF INJECTIONS
DE69522551T DE69522551T2 (en) 1994-02-14 1995-02-14 DEVICE FOR SELF-ADMINISTRATING INJECTIONS
JP52128195A JP3686083B2 (en) 1994-02-14 1995-02-14 Drug injection device
EP95909492A EP0744975B1 (en) 1994-02-14 1995-02-14 Self administered injection pen apparatus
DK95909492T DK0744975T3 (en) 1994-02-14 1995-02-14 Pen injector self-administration device
CA002181802A CA2181802C (en) 1994-02-14 1995-02-14 Self administered injection pen apparatus and method

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US195,307 1994-02-14
US08/195,307 US5514097A (en) 1994-02-14 1994-02-14 Self administered injection pen apparatus and method

Publications (2)

Publication Number Publication Date
WO1995021645A1 WO1995021645A1 (en) 1995-08-17
WO1995021645B1 true WO1995021645B1 (en) 1995-09-08

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1995/001509 WO1995021645A1 (en) 1994-02-14 1995-02-14 Self administered injection pen apparatus and method

Country Status (8)

Country Link
US (1) US5514097A (en)
EP (1) EP0744975B1 (en)
JP (1) JP3686083B2 (en)
AT (1) ATE205097T1 (en)
DE (1) DE69522551T2 (en)
DK (1) DK0744975T3 (en)
ES (1) ES2162911T3 (en)
WO (1) WO1995021645A1 (en)

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