WO1995016435A3 - Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent - Google Patents

Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent Download PDF

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Publication number
WO1995016435A3
WO1995016435A3 PCT/US1994/014196 US9414196W WO9516435A3 WO 1995016435 A3 WO1995016435 A3 WO 1995016435A3 US 9414196 W US9414196 W US 9414196W WO 9516435 A3 WO9516435 A3 WO 9516435A3
Authority
WO
WIPO (PCT)
Prior art keywords
solution containing
steroidal antiinflammatory
containing non
antiinflammatory agent
irrigating solution
Prior art date
Application number
PCT/US1994/014196
Other languages
French (fr)
Other versions
WO1995016435A2 (en
Inventor
Gerald D Cagle
Ole J Lorenzetti
Owen Gan
Original Assignee
Alcon Lab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alcon Lab Inc filed Critical Alcon Lab Inc
Priority to AU13996/95A priority Critical patent/AU1399695A/en
Priority to JP7516860A priority patent/JPH09506620A/en
Priority to EP95905340A priority patent/EP0734248A1/en
Publication of WO1995016435A2 publication Critical patent/WO1995016435A2/en
Publication of WO1995016435A3 publication Critical patent/WO1995016435A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Abstract

Pharmaceutical compositions useful in ophthalmic surgery are described. The compositions include one or more non-steroidal antiinflammatory drugs, and are useful for preventing or treating ophthalmic inflammation and other conditions associated with ophthalmic surgery. Methods of using the compositions in connection with ophthalmic surgical procedures are also described.
PCT/US1994/014196 1993-12-17 1994-12-13 Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent WO1995016435A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU13996/95A AU1399695A (en) 1993-12-17 1994-12-13 Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent
JP7516860A JPH09506620A (en) 1993-12-17 1994-12-13 Improved intraocular irrigation solution containing non-steroidal anti-inflammatory agents
EP95905340A EP0734248A1 (en) 1993-12-17 1994-12-13 Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US16946893A 1993-12-17 1993-12-17
US08/169,468 1993-12-17

Publications (2)

Publication Number Publication Date
WO1995016435A2 WO1995016435A2 (en) 1995-06-22
WO1995016435A3 true WO1995016435A3 (en) 1995-07-06

Family

ID=22615834

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1994/014196 WO1995016435A2 (en) 1993-12-17 1994-12-13 Improved intraocular irrigating solution containing non-steroidal antiinflammatory agent

Country Status (5)

Country Link
EP (1) EP0734248A1 (en)
JP (1) JPH09506620A (en)
AU (1) AU1399695A (en)
CA (1) CA2179147A1 (en)
WO (1) WO1995016435A2 (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2206119C (en) * 1994-12-12 2008-05-13 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain, inflammation and spasm
AU4467396A (en) * 1994-12-12 1996-07-10 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain, inflammation and spasm
US7091181B2 (en) 1994-12-12 2006-08-15 Omeros Corporation Method of inhibition of pain and inflammation during surgery comprising administration of soluble TNF receptors
US6492332B1 (en) 1995-12-12 2002-12-10 Omeros Corporation Irrigation solution and methods for inhibition of tumor cell adhesion, pain and inflammation
US6413961B1 (en) 1995-12-12 2002-07-02 Omeros Medical Systems, Inc. Irrigation solution and method for inhibition of pain and inflammation
CA2866848C (en) 2002-07-30 2017-01-03 Omeros Corporation Ophthalmologic irrigation solutions and method
AU2013201465B2 (en) * 2012-10-24 2016-03-03 Rayner Surgical (Ireland) Limited Stable preservative-free mydriatic and anti-inflammatory solutions for injection
TWI809304B (en) 2014-12-01 2023-07-21 奥默羅斯公司 Anti-inflammatory and mydriatic intracameral solutions for inhibition of postoperative ocular inflammatory conditions
CN111494307A (en) * 2019-01-30 2020-08-07 北京普德康利医药科技发展有限公司 Flurbiprofen injection
US11883382B2 (en) 2021-07-23 2024-01-30 Somerset Therapeutics, Llc Buffer-free ophthalmological compositions of ketorolac and phenylephrine and applications thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076658A2 (en) * 1981-10-05 1983-04-13 Alcon Laboratories, Inc. Ophthalmic irrigating solution
US4550022A (en) * 1981-10-05 1985-10-29 Alcon Laboratories, Inc. Tissue irrigating solution
EP0306984A1 (en) * 1987-09-11 1989-03-15 Syntex (U.S.A.) Inc. Preservative system for ophtalmic formulations
EP0364266A2 (en) * 1988-10-12 1990-04-18 Eye Research Institute Of Retina Foundation Inc NSAID and/or EGF for enhancing the healing of corneal endothelial wounds
US5051443A (en) * 1988-10-12 1991-09-24 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0076658A2 (en) * 1981-10-05 1983-04-13 Alcon Laboratories, Inc. Ophthalmic irrigating solution
US4550022A (en) * 1981-10-05 1985-10-29 Alcon Laboratories, Inc. Tissue irrigating solution
EP0306984A1 (en) * 1987-09-11 1989-03-15 Syntex (U.S.A.) Inc. Preservative system for ophtalmic formulations
EP0364266A2 (en) * 1988-10-12 1990-04-18 Eye Research Institute Of Retina Foundation Inc NSAID and/or EGF for enhancing the healing of corneal endothelial wounds
US5051443A (en) * 1988-10-12 1991-09-24 Eye Research Institute Of Retina Foundation, Inc. Method for enhancing healing of corneal endothelial wounds

Also Published As

Publication number Publication date
AU1399695A (en) 1995-07-03
JPH09506620A (en) 1997-06-30
CA2179147A1 (en) 1995-06-22
WO1995016435A2 (en) 1995-06-22
EP0734248A1 (en) 1996-10-02

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