WO1995006122A3 - Recombinant alternaria alternata allergenes - Google Patents

Recombinant alternaria alternata allergenes Download PDF

Info

Publication number
WO1995006122A3
WO1995006122A3 PCT/AT1994/000121 AT9400121W WO9506122A3 WO 1995006122 A3 WO1995006122 A3 WO 1995006122A3 AT 9400121 W AT9400121 W AT 9400121W WO 9506122 A3 WO9506122 A3 WO 9506122A3
Authority
WO
WIPO (PCT)
Prior art keywords
allergenes
recombinant
acid sequences
sequences
nucleic
Prior art date
Application number
PCT/AT1994/000121
Other languages
German (de)
French (fr)
Other versions
WO1995006122A2 (en
Inventor
Gernot Achatz
Hannes Oberkofler
Birgit Simon
Andrea Unger
Erich Lechenauer
Reinhold Hirschwehr
Christoph Ebner
Dietrich Kraft
Hans-Joerg Prillinger
Michael Breitenbach
Original Assignee
Biomay Prod & Handel
Gernot Achatz
Hannes Oberkofler
Birgit Simon
Andrea Unger
Erich Lechenauer
Reinhold Hirschwehr
Christoph Ebner
Dietrich Kraft
Prillinger Hans Joerg
Michael Breitenbach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biomay Prod & Handel, Gernot Achatz, Hannes Oberkofler, Birgit Simon, Andrea Unger, Erich Lechenauer, Reinhold Hirschwehr, Christoph Ebner, Dietrich Kraft, Prillinger Hans Joerg, Michael Breitenbach filed Critical Biomay Prod & Handel
Priority to EP94923587A priority Critical patent/EP0714442A1/en
Priority to AU73772/94A priority patent/AU7377294A/en
Priority to JP7507226A priority patent/JPH09503654A/en
Priority to CA002170355A priority patent/CA2170355A1/en
Publication of WO1995006122A2 publication Critical patent/WO1995006122A2/en
Publication of WO1995006122A3 publication Critical patent/WO1995006122A3/en
Priority to NO960748A priority patent/NO960748L/en
Priority to FI960882A priority patent/FI960882A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/37—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from fungi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Abstract

The invention concerns recombinant DNA molecules which code for polypeptides possessing the antigenicity of the allergenes Alta53, Alta22 and Alta11 or for peptides having at least one epitope of these allergenes. These molecules are characterized in that they contain nucleic-acid sequences which correspond in homologous fashion to the sequences 1, 3-5, 7-9, 12 and 13 or to parts of these sequences, or nucleic-acid sequences which hybridize with the above nucleic-acid sequences under strictly controlled conditions.
PCT/AT1994/000121 1993-08-27 1994-08-24 Recombinant alternaria alternata allergenes WO1995006122A2 (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
EP94923587A EP0714442A1 (en) 1993-08-27 1994-08-24 Recombinant alternaria alternata allergenes
AU73772/94A AU7377294A (en) 1993-08-27 1994-08-24 Recombinant alternaria alternata allergenes
JP7507226A JPH09503654A (en) 1993-08-27 1994-08-24 Recombinant Alternaria alternata allergen
CA002170355A CA2170355A1 (en) 1993-08-27 1994-08-24 Recombinant alternaria alternata allergenes
NO960748A NO960748L (en) 1993-08-27 1996-02-23 Recombinant Alternaria alternata allergens
FI960882A FI960882A (en) 1993-08-27 1996-02-26 Alternaria alternata recombinant allergens

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT0172693A AT400723B (en) 1993-08-27 1993-08-27 RECOMBINANT ALTERNARIA ALTERNATA ALLERGENS
ATA1726/93 1993-08-27

Publications (2)

Publication Number Publication Date
WO1995006122A2 WO1995006122A2 (en) 1995-03-02
WO1995006122A3 true WO1995006122A3 (en) 1995-07-13

Family

ID=3519690

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT1994/000121 WO1995006122A2 (en) 1993-08-27 1994-08-24 Recombinant alternaria alternata allergenes

Country Status (8)

Country Link
EP (1) EP0714442A1 (en)
JP (1) JPH09503654A (en)
AT (1) AT400723B (en)
AU (1) AU7377294A (en)
CA (1) CA2170355A1 (en)
FI (1) FI960882A (en)
NO (1) NO960748L (en)
WO (1) WO1995006122A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE520392C2 (en) 1996-09-27 2003-07-01 Creative Peptides Sweden Ab C Specific peptides for the treatment of diabetes mellitus
JP2003524384A (en) 1998-11-03 2003-08-19 アドヘレックス テクノロジーズ インコーポレイテッド Compounds and methods for modulating claudin-mediated function
US6756356B2 (en) 1998-11-03 2004-06-29 Adherex Technologies, Inc. Compounds and methods for modulating claudin-mediated functions
GB201209868D0 (en) * 2012-06-01 2012-07-18 Circassia Ltd Alternaria peptides

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
A. SILVANOVICH ET AL: "Nucleotide sequence and analysis of three cDNAs coding for Poa p IX isoallergens of Kentucky Bluegrass pollen", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 266, no. 2, 15 January 1991 (1991-01-15), MD US, pages 1204 - 1210 *
C. BARNES ET AL: "Comparison of proteins from four strains of Alternaria using two-dimensional electrophoresis", THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 89, no. 1, pages 283 *
D. KRAFT AND M. SEHON: "Mol. Biol. Immunol. Allergens", CRC, BOCA RATON *
H. BREITENEDER: "The gene coding for the major birch pollen allergen BetvI, is highly homologous to a pea disease resistance response gene", EMBO JOURNAL, vol. 8, pages 1935 - 1938 *
H. MARGALIT ET AL: "Prediction of immunodominant helper T cell antigenic sites from the primary sequence", JOURNAL OF IMMUNOLOGY, vol. 138, no. 7, 1 April 1987 (1987-04-01), pages 2213 - 2229 *
H. SANCHEZ ET AL: "cDNA sequence of an Alternaria allergen", THE JOURNAL OF ALLERGY AND CLINICAL IMMUNUNOLOGY, vol. 89, no. 1, pages 241 *
I. CURRAN ET AL: "Purification and characterization of a low molecular weight antigen from Alternaria alternata", THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 89, no. 1, pages 283 *
I. OLSON ET AL: "Affinity purification of a major Alternaria anitgen using a monoclonal antibody", THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 83, no. 1, pages 292 *
J. FOLGERT ET AL: "Characterization of an Alternaria allergen", THE JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, vol. 89, no. 1, pages 283 *
R. YOUNG AND R. DAVIS: "Efficient isolation of genes by using antibody probes", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA, vol. 80, WASHINGTON US, pages 1194 - 1198 *

Also Published As

Publication number Publication date
AT400723B (en) 1996-03-25
NO960748L (en) 1996-04-24
CA2170355A1 (en) 1995-03-02
FI960882A (en) 1996-04-24
AU7377294A (en) 1995-03-21
FI960882A0 (en) 1996-02-26
WO1995006122A2 (en) 1995-03-02
EP0714442A1 (en) 1996-06-05
NO960748D0 (en) 1996-02-23
JPH09503654A (en) 1997-04-15
ATA172693A (en) 1995-07-15

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