WO1994011510A3 - Modulators of hematopoietic progenitor cells - Google Patents

Modulators of hematopoietic progenitor cells Download PDF

Info

Publication number
WO1994011510A3
WO1994011510A3 PCT/US1993/010728 US9310728W WO9411510A3 WO 1994011510 A3 WO1994011510 A3 WO 1994011510A3 US 9310728 W US9310728 W US 9310728W WO 9411510 A3 WO9411510 A3 WO 9411510A3
Authority
WO
WIPO (PCT)
Prior art keywords
hematopoietic progenitor
modulators
progenitor cells
materials
quantifying
Prior art date
Application number
PCT/US1993/010728
Other languages
French (fr)
Other versions
WO1994011510A2 (en
Inventor
Jeffrey G Moore
Martha W Bond
David S Campbell
Frank D Lee
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Priority to AU55949/94A priority Critical patent/AU5594994A/en
Publication of WO1994011510A2 publication Critical patent/WO1994011510A2/en
Publication of WO1994011510A3 publication Critical patent/WO1994011510A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Abstract

Compositions are provided, including nucleic acids, polypeptides, and antibodies, that can be used to regulate hematopoietic progenitor cell development or differentiation. Methods for using these materials, as well as kits for quantifying the materials, are also provided.
PCT/US1993/010728 1992-11-16 1993-11-15 Modulators of hematopoietic progenitor cells WO1994011510A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU55949/94A AU5594994A (en) 1992-11-16 1993-11-15 Modulators of hematopoietic progenitor cells

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97678992A 1992-11-16 1992-11-16
US07/976,789 1992-11-16

Publications (2)

Publication Number Publication Date
WO1994011510A2 WO1994011510A2 (en) 1994-05-26
WO1994011510A3 true WO1994011510A3 (en) 1994-09-15

Family

ID=25524469

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/010728 WO1994011510A2 (en) 1992-11-16 1993-11-15 Modulators of hematopoietic progenitor cells

Country Status (2)

Country Link
AU (1) AU5594994A (en)
WO (1) WO1994011510A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5824789A (en) * 1995-06-07 1998-10-20 Systemix, Inc. Human growth factors, nucleotide sequence encoding growth factors, and method of use thereof

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
BLOOD, vol. 72, no. 2, 1988, pages 806 - 810 *
CHEMICAL ABSTRACTS, vol. 107, no. 19, 9 November 1987, Columbus, Ohio, US; abstract no. 173298, H. HINSSEN ET AL: "Gelsolin is expressed in early erythroid progenitor cells and negatively regulated during erytrhropoiesis" page 482; *
CHEMICAL ABSTRACTS, vol. 109, no. 15, 10 October 1988, Columbus, Ohio, US; abstract no. 123147, E. NISKANEN ET AL: "In vivo effect of human erythroid-potentiating activity on hematopoiesis in mice" page 135; *
E. HUANG ET AL: "The hematopoietic growth factor KL is encoded by SI locus and is the ligand of the c-kit receptor, the gene product of the W locus", CELL., vol. 63, 5 October 1990 (1990-10-05), CAMBRIDGE, NA US, pages 225 - 233, XP023908038, DOI: doi:10.1016/0092-8674(90)90303-V *
F-X YU ET AL: "gCap39, a calcium ion- and polyphosphoinositide- regulated actin capping protein", SCIENCE., vol. 250, December 1990 (1990-12-01), LANCASTER, PA US, pages 1414 - 1415 *
G. DABIRI ET AL: "Molecular cloning of human macrophage capping protein cDNA", JOURNAL OF BIOLOGICAL CHEMISTRY., vol. 267, no. 23, 15 August 1992 (1992-08-15), BALTIMORE US, pages 16545 - 16552 *
G. PRENDERGAST AND E. ZIFF: "Mbh1: a novel gelsolin/severin-related protein which binds actin in vitro and exhibits nuclear localization in vivo", EMBO JOURNAL., vol. 10, no. 4, 1991, EYNSHAM, OXFORD GB, pages 757 - 766 *
JOURNAL OF CELL BIOLOGY, vol. 105, no. 3, 1987, pages 1425 - 1433 *
L. FELDMAN AND D. DANIAK: "B-lymphocyte-derived erythroid burst-promoting activity is distinct from other known lymphokines", BLOOD, vol. 73, no. 7, 15 May 1989 (1989-05-15), pages 1814 - 1820 *
M. TRUCCO ET AL: "A novel human lymphokine that inhibits haematopoietic progenitor cell rpoliferation", NATURE., vol. 309, 1984, LONDON GB, pages 166 - 168 *

Also Published As

Publication number Publication date
WO1994011510A2 (en) 1994-05-26
AU5594994A (en) 1994-06-08

Similar Documents

Publication Publication Date Title
AU555575B2 (en) Polypeptide preparation in vertebrate cell culture
AU4270796A (en) Improvements in or relating to endometrial function
AU6189680A (en) Buffer composition and method for the electrophoretic separation of proteins
EP0247730A3 (en) Antibodies, their preparation and use and products containing them
IE56720B1 (en) Methods and compositions for expression of competent eukaryotic gene products
AU8661498A (en) Mammalian cell membrane proteins; related reagents
DE69102651T2 (en) PROTEASER-RESISTANT PDGF AND ITS USES.
GB2239315B (en) Mutant fungal strain detection
WO1994011510A3 (en) Modulators of hematopoietic progenitor cells
AU8045294A (en) Methods for producing protein C
AU524979B2 (en) Purified serum factors in animal cell culture medium
AU2233092A (en) Characterization or determination of the amount of mammalian cells by means of antibodies
AU6189780A (en) Buffer composition and method for the electrophoretic separation of proteins
ES2047946T3 (en) CELL CULTURE METHODS FOR PRODUCING ACTIVATED C PROTEIN.
CA2284133A1 (en) Novel cell line and screening method with the use of the same
WO2000028054A3 (en) Plant proteins that interact with nuclear matrix proteins and function as transcriptional activators
AU3620195A (en) Protein mixture prepared from serum for use as component in media for in vitro culture of animal cells

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AU BB BG BR BY CA CZ FI HU JP KR KZ LK LV MG MN MW NO NZ PL RO RU SD SK UA UZ VN

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
NENP Non-entry into the national phase

Ref country code: CA

122 Ep: pct application non-entry in european phase