WO1994011272A1 - Bouchon indicateur possedant un schema posologique a selectionner - Google Patents

Bouchon indicateur possedant un schema posologique a selectionner Download PDF

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Publication number
WO1994011272A1
WO1994011272A1 PCT/US1993/011003 US9311003W WO9411272A1 WO 1994011272 A1 WO1994011272 A1 WO 1994011272A1 US 9311003 W US9311003 W US 9311003W WO 9411272 A1 WO9411272 A1 WO 9411272A1
Authority
WO
WIPO (PCT)
Prior art keywords
window
symbols
indicator
cover
outer cover
Prior art date
Application number
PCT/US1993/011003
Other languages
English (en)
Inventor
Gage Garby
Jerome L. Olivas
Original Assignee
Senetics, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Senetics, Inc. filed Critical Senetics, Inc.
Priority to AU56682/94A priority Critical patent/AU5668294A/en
Priority to EP94902243A priority patent/EP0684927A1/fr
Publication of WO1994011272A1 publication Critical patent/WO1994011272A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J7/00—Devices for administering medicines orally, e.g. spoons; Pill counting devices; Arrangements for time indication or reminder for taking medicine
    • A61J7/04—Arrangements for time indication or reminder for taking medicine, e.g. programmed dispensers

Definitions

  • the present invention relates to closure members for containers, bottles and the like and, more particularly, to closure members having indicator means to indicate the number of times the container has been opened.
  • the invention can also be used for any other application in which the number of times a given activity is performed must be indicated.
  • medical drugs have a predetermined therapeutic range in which the .effects of taking the drug are beneficial. Under-utilization of a drug may endanger the user with the drug's side effects without reaching levels necessary for a therapeutic action. On the other hand, over-utilization may cause side effects or toxicity to a much greater extent than any possible benefit. Thus it is critically important that a patient follow prescribed directions on medications, yet frequently patients forget whether they have taken medication and either omit doses or repeat them.
  • a drawback to the window arrangements in the prior art is that they are usable only with a single dosing regimen.
  • a window which displays consecutively "M, Tu, W, Th, F, Sa, Su” is usable only with medicine that is to be taken once a day. If it is used with medicine that is to be taken twice a day, the symbols visible through the window will not match the actual day and the device will confuse more than assist the user.
  • a window which displays consecutively "Ml, M2, Tul, Tu2, Wl, W2, Thl, Th2, Fl, F2, Sal, Sa2, Sul, Su2” for medicine that is to be taken twice a day will not be usable with medicine that is to be taken once a day.
  • the device of U.S Patent 4,666,051 issued May 19, 1987 to Trick has an indicator wheel with a serrated rim projecting above and below the plane of the wheel.
  • the serrations engage mating serrations in upper and lower elements in order to drive the indicator mechanism.
  • the serrations are rigid and, therefore, tend to wear excessively as they slide past one another.
  • the device of European Patent Application No. 87100917.2, published July 27, 1987, by Schwab has a cup-shaped exterior element that engages a frustoconical closure cap.
  • the Schwab device is somewhat complicated in design and manufacture.
  • the device of U.S. Patent 4,220,247 issued September 2, 1980 to Kramer also includes a cup-shaped exterior element which engages an inner element. It appears that Wachsmann, Livingston, Trick and Schwab all utilize an ordinary symbol arrangement which is usable only with a single dosing regimen.
  • an improved indicator cap in the manner of the present invention that allows an indicator device to be used on a medicine container for use with more than a single dosing regimen.
  • the dosing regimen to be indicated by the device could be chosen simply and effectively at the time the device is to be used.
  • an indicator cap that provides positive controlled movement of the index on both opening and closing of the device, while also providing an indication to the user that the index has functioned properly each time the device is used.
  • the basic design of such a device can also be used in other applications where it is necessary to have a record of the number of times a given event occurs.
  • Another object of this invention is to provide an indicator device in which the indicator system can either be operated or not operated by the user.
  • Yet another object of the invention is to provide an audible sound to confirm that the device has been rotated sufficiently to move the index to the next location and to also provide an audible sound when the device has been rotated sufficiently to re-cock the device for the next open-close sequence.
  • Still another object is to provide space within the device for the locking mechanisms to slide past each other when not engaged to allow such mechanisms to work reliably over a long period of time.
  • Another object of the present invention is to combine functions usually requiring several components into single components to reduce the complexity of the device and provide ease of manufacturability and assembly using standard injection molding and assembly techniques.
  • Another object of the present invention is to provide an indicator assembly that can easily be fitted to an ordinary container without requiring any special modifications to the container itself.
  • Another object is to provide a device with indicator symbols that can be sensed by touch such as raised letters or braille. Another object is to provide a device that can be easily grasped by elderly or impaired patients, as by including grasp-facilitating elements on the device.
  • Another object is to provide a device which is easily manufactured and assembled with a minimum of parts.
  • FIG. 1 is a perspective view of a medicine container with an indicator device of the present invention.
  • FIG. 2 is a plan view of an indicator wheel with a set of indicator symbols according to the present invention.
  • FIG. 3 is a plan view of the outer cover with a window and a set of window covers according to the present invention.
  • FIG. 4 is a detail of the window and window covers of the present invention.
  • FIG. 5 is a sectional view taken along line 5-5 of FIG. 4.
  • FIG. 6 is a sectional view taken along line 6-6 of FIG. 4.
  • FIG. 7 is a detail of the window and window covers showing certain labelling in the present invention.
  • FIG. 8 is a perspective view of an alternative embodiment of the invention.
  • FIG. 8A is a sectional view taken along line 8A-8A of FIG. 8.
  • FIG. 9 is a perspective view of a further alternative embodiment of the invention.
  • FIG. 9A is a sectional view taken along line 9A-9A of FIG. 9.
  • FIG. 10 is a perspective view of a further alternative embodiment of the invention.
  • FIG. 10A is a sectional view taken along line 10A-10A of FIG. 10.
  • FIG. 1 A pictorial view of a medicine bottle 12 with an indicator cap 14 is shown in FIG. 1.
  • Such devices in general are known in the art and are not described in detail here.
  • such a device is described in detail in U.S. Patent No. 5,009,388 by Barker of which the present invention is a continuation-in-part, and in U.S. Patent No. 4,011,829 by Wachsmann.
  • the medicine bottle 12 is of the ordinary plastic type for holding a number of medicinal pills or tablets.
  • the neck of the bottle is threaded to receive the threaded indicator cap 14.
  • the indicator cap in the preferred embodiment includes an outer cap with a window 16 therethrough, an inner retainer and an indicator wheel disposed between the outer cover and inner retainer having a set of indicator symbols selectively visible through the window 16.
  • a pawl on one of the indicator wheel and the inside surface of the outer cover and a set of engaging teeth on the other of the indicator wheel and the inside surface of the outer cover allow rotation of the outer cover relative to the indicator wheel in a first rotational direction but not in a second rotational direction opposite the first rotational direction.
  • a pawl on one of the indicator wheel and the inner retainer and a set of engaging teeth on the other of the indicator wheel and the inner retainer allow rotation of the indicator wheel in the second rotational direction but not in the first rotational direction.
  • “Lost motion” is provided between the outer cover and the inner retainer by a set of circumferential tabs on one of those members and circumferential engaging grooves on the other of those members.
  • the tabs have a shorter circumferential length than the grooves, so that the outer cover has a limited range of rotational motion relative to the inner retainer.
  • the outer cover When the outer cover is then rotated in the opposite direction (such as counterclockwise), the outer cover together with the indicator device rotate relative to the inner retainer through the limited range of motion available from the tabs and grooves, while the inner retainer stays stationary. This causes an advancement of the tooth past another pawl in the tee ⁇ _h and pawl on the indicator wheel and inner retainer to produce another audible "click" to confirm the proper operation of the device to the user.
  • the limited range of rotational motion between the outer cover and inner retainer is exhausted by the tabs reaching the opposite circumferential end of the grooves, the inner retainer begins rotating with the outer cover to unscrew the device from the bottle and access the contents.
  • the lost motion indicator device using the window described herein may be used in combination with a child-resistant mechanism which resists the removal of the closure from the bottle by a child.
  • Common child-resistant mechanisms include the "push and turn" type which require the application of an axial force urging the closure toward the container simultaneous with the rotation of the closure. The axial force may cause the engagement of lugs and notches that are positioned on the closure and the indicator device in the manner of parent application no. 07/718,354 filed June 21, 1991, or may disengage a set of lugs and bayonet grooves on the closure and the container neck in the case of a closure and container that use that type of closing mechanism rather than threads.
  • the aspect of the indicator cap 12 to which the present invention is particularly pertinent concerns the window 16 for the display of indicator symbols on the indicator wheel.
  • the indicator wheel 30 having a set of indicator symbols 32 is shown in FIG. 2; a top plan view of the outer cover 14 showing the window 16 is shown in FIG. 3; details of the window 16 are shown in FIGs. 5-6; and the combination of the indicator wheel 30 and the overlying outer cover 14 with window 16 to display the indicator symbols 32 on the indicator wheel 30, is shown in FIG. 4.
  • the indicator wheel 30 in the preferred embodiment is a circular disk-shaped element having a diameter allowing it to rest within the outer cover 16 (from FIG. 1) and a thickness sufficient to impart some rigidity to the disk.
  • An indicator wheel 30 in a commonly sized indicator device might have a diameter on the order of an inch and a thickness of a sixteenth to an eight of an inch.
  • the indicator wheel 30 will also generally include a means to engage the outer cover 16 such as a pawl on its upper or circumferential surface (not shown) to engage mating teeth on the inside surface of the outer cover as mentioned above.
  • the indicator wheel 30 has printed onto the top surface a set of indicator symbols.
  • the symbols include an inner set 34 and an outer set 36 in which the inner set 34 is positioned radially inward from the outer set 36. Both sets of symbols 34 and 36 fit within the window 16.
  • the outer set of symbols 36 is a set of abbreviations for consecutive days of two weeks, namely "M, Tu, W, Th, F, Sa, Su, M, Tu, W, Th, F, Sa, Su" . These fourteen symbols correspond to fourteen teeth on the teeth that mate with the pawl on the indicator wheel 30 and outer cover 14, so that each click of the pawl past a tooth positions one new symbol in the window 16.
  • the inner set of symbols 34 is a set of fourteen abbreviations for consecutive days of the week.
  • the outer symbols 36 include two numbers for each day, as in "Ml, M2, Tul, Tu2, Wl, W2, Thl, Th2, Fl, F2, Sal, Sa2, Sul, Su2".
  • the formatting of the symbols shown in FIG. 2 positions the numeral below the day abbreviation for the inner set of symbols 36.
  • the outer symbols 36 can be used when the device is to remind the user to take one dose a day. In that event, each time the device is removed from and replaced onto the container to obtain a dose of medication, the outer symbols 36 will advance one position to a new day. The user thereby is alerted whether he has taken his medication that day or not.
  • the inner symbols 34 can be used to remind the user to take two doses a day. In that event, each time the device is removed from and replaced onto the container to obtain a dose of medication, the inner symbols will advance one position. Because each day includes a "1" position and a "2" position, the user is thereby alerted to take two doses a day.
  • the outer cover 14 is shown in a top plan view in FIG. 3. That view also shows the window 16 through the outer cover 14, and the inner window cover 20 and outer window cover 22.
  • the inner window cover 20 covers the radially inner portion of the window 16 while the outer window cover 22 covers the radially outer portion of the window 16.
  • the inner window 20 and outer window 22 are joined to the boundary of the window 16 by tabs 24 and 25 for the inner window cover 20, and tabs 26 and 27 for the outer window cover 22.
  • the tabs 24, 25, 26 and 27 are shown best in FIGs. 4 and 5. They are essentially narrow tabs that extend from the window covers 20 and 22 to the boundary of the window 16.
  • the tabs 24, 25, 26 and 27 may be approximately the same thickness as the window covers 20 and 22, or may be thinned in comparison to the window covers 20 and 22 in the manner shown in FIG. 6.
  • the inner window cover 20 fits within the radially inner portion of the window 16 and therefore has a slightly smaller perimeter than the boundaries of that portion of the window.
  • the outer window cover 22 fits within the radially outer portion of the window and therefore has a slightly smaller perimeter than that portion of the window.
  • the dimension of the inner window 20 in the radial direction is sufficient to cover the inner set of symbols 34 on the indicator wheel 30 while the dimension of the outer window 22 in the radial direction is sufficient to cover the outer set of symbols 36 on the indicator wheel 30.
  • each window cover 20 and 22 may include printed labels to indicate which portion of the window is to be used for a desired dosing schedule. Such instructions can be on the outer cover 14 or on the window covers 20 and 22 as shown in FIG. 7.
  • the inner window cover 24 has a label stating "1 Time A Day” with an arrow pointing to a tab 26 attaching the outer window cover 22 to the outer cover 14. If the device is desired for use with medicine to be taken once a day, the user knows from this label to break tab 26 (and then tab 27) to remove the outer window cover 22 and expose the twice a day outer symbols 36 on the indicator wheel 30. The removal of the outer window cover 22 also effects a removal of the labelling on the outer window cover, leaving only the labelling on the inner window cover 20.
  • the user is left with a device for once a day dosing that is labelled as such.
  • the device is for use with twice a day dosing, the user is instructed by the label "2 Times A Day” and the accompanying arrow to break tab 25 (and tab 24) attaching the inner window cover 29 to the outer cover 14 to remove the inner window cover 20 and expose the twice a day symbols of the inner symbols 34 on the indicator wheel 30.
  • the removal of the inner window cover 20 also effects a removal of the labelling on the inner window cover 20.
  • the user is left with a device for twice a day dosing that is labelled as such.
  • the chosen window cover 20 or 22 is removed from the window 16 by the user breaking at least one of the tabs 24, 25 26 or 27 and pulling the window cover 20 or 22 away from the window 16.
  • the breaking of the tabs 24, 25, 26 or 27 may be assisted by the use of a pencil, toothpick, knife, fingernail or other somewhat sharp object which can be used to press the window cover 20 or 22 downward to shear the tabs 24, 25, 26 or 27, or which can be used to insert in a slot between the window cover 20 or 22 and the boundary of the window 16 to pry the window cover 20 or 22 away from the outer cover 14.
  • the outer cover 14 and window covers 20 and 22 are injection-moldable plastic in the preferred embodiment, but it will be apparent that other materials may be used.
  • the means for attaching the window covers 20 and 22 to the outer cover 14 is described as the tabs 24, 25, 26 and 27, which are preferably injection-moldable plastic that is formed with the forming of the outer cover 14, but any other attachment means is satisfactory provided it allows the window covers 20 and 22 to be removed from obstructing the window 16.
  • the window covers could be paper or plastic sheets which are simply adhered to the boundaries of the window 16. They could also be part of a larger paper or plastic sheet which covers part or all of the type of the outer cover 14, and is separable from that larger sheet by scored lines or tearable folds.
  • FIG. 8 shows a perspective view of the outer cover 14 with the widow 16 therethrough, along with an inner window cover 120 and outer window cover 122.
  • the inner window cover 120 is attached to the outer cover 14 by a tab 124 similar to the tab 24 that attaches the inner window cover 20 to the outer cover 14 in the embodiment described above and shown in FIGs. 2-7.
  • the tab 124 connects the inner window cover 120 to the outer cover 14 at the radially inner boundary of the window 16 rather than at one of the sides of the window 16 as in the embodiment of FIGs. 2-7.
  • the inner window cover 120 has an upstanding lip 121 at its radially outer edge.
  • the purpose of the inner window cover lip 121 is to provide something for a user to grasp in order to pull the inner window cover 120 from the window 16.
  • the outer window cover 122 is attached to the outer cover 16 by a tab 126 at the radially outer boundary of the window 16 rather than at the sides of the window 16, and the outer window 122 has its own upstanding lip 123 so that the user can grasp and remove the outer cover 122. Therefore, this embodiment would not require any tool such as a pencil to punch the window covers 120 and 122 from the window 16.
  • the embodiment shown in FIG. 9 utilizes an inner window cover 220 and outer window cover 222 which slide to open the window 16.
  • the inner window cover 220 is fitted into a slot 221 which extends into the thickness of the top of the outer cover 14 as better shown in the cross-sectional view of FIG. 9A taken along line 9A-9A of FIG. 9.
  • One side of the inner window cover 222 has an upstanding edge 235 which allows the user to easily slide open the inner window cover 220.
  • the outer window cover 222 slides through an outer window cover slot 223 in the thickness of the top of the outer cover 14 (which may be undivided from the inner window cover slot 221 as shown in FIG. 9) and has an upstanding edge 237.
  • the user operates this embodiment by selecting the window cover 220 or 222 to be opened, and then opens it by sliding it into its respective slot 221 or 223 using the upstanding edge 235 or 237.
  • This embodiment has the notable advantage that the user's selection of a window cover to be opened is reversible; the user can simply close an opened window cover by sliding the window cover back over the window and then open the other window cover instead.
  • the embodiment shown in FIG. 10 includes a paper or plastic sheet for the inner window cover 320 and another paper or plastic sheet for the outer window cover 322.
  • Each window cover 320 and 322 is adhered to the outer cover 14 in the region surrounding the window 16 by an adhesive on the side of the sheet facing the outer cover 14.
  • Each of the window covers 320 and 322 is wider in the circumferential direction than the window 16, so that it overlaps the outer cover 14, thereby presenting an overlapping surface for application of the adhesive.
  • the window covers 320 and 322 may include ends 321 and 323 which are not adhered to the outer cover 14, so that they stand apart from the outer cover 14 to be grasped by the user, as better shown in FIG. 10A.
  • the user selects the window cover 320 or 322 to be removed, and then removes it by grasping the unadhered portion 321 or 323 and peeling the window cover 230 or 322 off the outer cover 14 to expose the desired portion of the window 16.
  • the device could instead use more than one window each with its own cover to cover the respective sets of indicator symbols.
  • the indicator symbol sets need not be concentric circles but could be located anywhere on the device.
  • the window covers 20 and 22 of FIG. 7 could be hingedly attached to the outer cover 14 by breaking away only one of the two tabs that attach each of them to the outer cover so that the remaining tab acts as a hinge.
  • a so called living hinge could extend along one side of the window cover to allow hinged opening.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medical Informatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

L'invention concerne un dispositif (12) porteur d'indications conformes à un schéma, tel que l'ouverture d'un couvercle d'un flacon de médicaments selon un schéma posologique. Une pluralité de schémas figurent sur un dispositif indicateur (12), et une fenêtre (16) permet de visualiser le schéma posologique à chaque prise. Un ensemble de couvercles (14) de fenêtres sont utilisés pour recouvrir les schémas. L'utilisateur peut sélectionner le schéma désiré en retirant le couvercle de la fenêtre qui recouvre ce schéma. Le dispositif (12) peut, par conséquent, être utilisé en mettant en ÷uvre plusieurs schémas selon les souhaits de l'utilisateur.
PCT/US1993/011003 1992-11-17 1993-11-12 Bouchon indicateur possedant un schema posologique a selectionner WO1994011272A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU56682/94A AU5668294A (en) 1992-11-17 1993-11-12 Indicator cap having selectable dosage schedule
EP94902243A EP0684927A1 (fr) 1992-11-17 1993-11-12 Bouchon indicateur possedant un schema posologique a selectionner

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US97751992A 1992-11-17 1992-11-17
US07/977,519 1992-11-17

Publications (1)

Publication Number Publication Date
WO1994011272A1 true WO1994011272A1 (fr) 1994-05-26

Family

ID=25525220

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1993/011003 WO1994011272A1 (fr) 1992-11-17 1993-11-12 Bouchon indicateur possedant un schema posologique a selectionner

Country Status (4)

Country Link
EP (1) EP0684927A1 (fr)
AU (1) AU5668294A (fr)
CA (1) CA2148254A1 (fr)
WO (1) WO1994011272A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8157128B2 (en) 1998-01-16 2012-04-17 Trudell Medical International Indicating device
US8578934B2 (en) 2003-10-28 2013-11-12 Trudell Medical International Indicating device with warning dosage indicator
US8596265B2 (en) 2008-10-22 2013-12-03 Trudell Medical International Modular aerosol delivery system
US8662075B2 (en) 1998-05-05 2014-03-04 Trudell Medical International Dispensing device
US8869735B2 (en) 2003-12-15 2014-10-28 Trudell Medical International, Inc. Dose indicating device
US8973784B2 (en) 2005-01-20 2015-03-10 Trudell Medical International Dispensing device
US9265901B2 (en) 2006-08-01 2016-02-23 Trudell Medical International Dispensing device

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4572376A (en) * 1982-09-16 1986-02-25 Wrennall Richard K Dial pill box
US4920912A (en) * 1988-03-10 1990-05-01 Kirkling William C Time dial for pharmaceutical containers
US5188251A (en) * 1992-05-05 1993-02-23 Owens-Illinois Closure Inc. Child resistant reminder closure
US5226539A (en) * 1992-06-29 1993-07-13 Cheng Lung C Pill container

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4572376A (en) * 1982-09-16 1986-02-25 Wrennall Richard K Dial pill box
US4920912A (en) * 1988-03-10 1990-05-01 Kirkling William C Time dial for pharmaceutical containers
US5188251A (en) * 1992-05-05 1993-02-23 Owens-Illinois Closure Inc. Child resistant reminder closure
US5226539A (en) * 1992-06-29 1993-07-13 Cheng Lung C Pill container

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP0684927A4 *

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8157128B2 (en) 1998-01-16 2012-04-17 Trudell Medical International Indicating device
US8505773B2 (en) 1998-01-16 2013-08-13 Trudell Medical International Indicating device
US9649455B2 (en) 1998-01-16 2017-05-16 Trudell Medical International Indicating device
US8944285B2 (en) 1998-01-16 2015-02-03 Trudell Medical International Indicating device
US8662075B2 (en) 1998-05-05 2014-03-04 Trudell Medical International Dispensing device
US9168343B2 (en) 1998-05-05 2015-10-27 Trudell Medical International Dispensing device
US8578934B2 (en) 2003-10-28 2013-11-12 Trudell Medical International Indicating device with warning dosage indicator
US9968748B2 (en) 2003-10-28 2018-05-15 Trudell Medical International Indicating device with warning dosage indicator
US8869735B2 (en) 2003-12-15 2014-10-28 Trudell Medical International, Inc. Dose indicating device
US8973784B2 (en) 2005-01-20 2015-03-10 Trudell Medical International Dispensing device
US9656032B2 (en) 2005-01-20 2017-05-23 Trudell Medical International Dispensing device
US9265901B2 (en) 2006-08-01 2016-02-23 Trudell Medical International Dispensing device
US10950149B2 (en) 2006-08-01 2021-03-16 Trudell Medical International Dispensing device
US8596265B2 (en) 2008-10-22 2013-12-03 Trudell Medical International Modular aerosol delivery system
US9032953B2 (en) 2008-10-22 2015-05-19 Trudell Medical International Modular aerosol delivery system
US9242057B2 (en) 2008-10-22 2016-01-26 Trudell Medical International Modular aerosol delivery system

Also Published As

Publication number Publication date
EP0684927A1 (fr) 1995-12-06
AU5668294A (en) 1994-06-08
CA2148254A1 (fr) 1994-05-26
EP0684927A4 (fr) 1995-09-07

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