WO1994007527A3 - Vasoactive peptide inhibition - Google Patents
Vasoactive peptide inhibition Download PDFInfo
- Publication number
- WO1994007527A3 WO1994007527A3 PCT/GB1993/002044 GB9302044W WO9407527A3 WO 1994007527 A3 WO1994007527 A3 WO 1994007527A3 GB 9302044 W GB9302044 W GB 9302044W WO 9407527 A3 WO9407527 A3 WO 9407527A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- hydroxyamino
- phenylalanine
- endothelin
- isobutylsuccinyl
- methylamide
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/225—Polycarboxylic acids
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Emergency Medicine (AREA)
- Gastroenterology & Hepatology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU48316/93A AU4831693A (en) | 1992-10-03 | 1993-10-01 | Vasoactive peptide inhibition |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9220845.3 | 1992-10-03 | ||
GB929220845A GB9220845D0 (en) | 1992-10-03 | 1992-10-03 | Vasoactive peptide inhibition |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1994007527A2 WO1994007527A2 (en) | 1994-04-14 |
WO1994007527A3 true WO1994007527A3 (en) | 1994-07-21 |
Family
ID=10722928
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1993/002044 WO1994007527A2 (en) | 1992-10-03 | 1993-10-01 | Vasoactive peptide inhibition |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU4831693A (en) |
GB (1) | GB9220845D0 (en) |
WO (1) | WO1994007527A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9320660D0 (en) * | 1993-10-07 | 1993-11-24 | British Bio Technology | Inhibition of cytokine production |
PL194240B1 (en) | 1998-02-07 | 2007-05-31 | British Biotech Pharm | Antibacterial agents |
GB9818605D0 (en) | 1998-08-26 | 1998-10-21 | Glaxo Group Ltd | Formamide compounds as therepeutic agents |
US6172064B1 (en) | 1998-08-26 | 2001-01-09 | Glaxo Wellcome Inc. | Formamides as therapeutic agents |
US6329400B1 (en) | 1998-08-26 | 2001-12-11 | Glaxo Wellcome Inc. | Formamide compounds as therapeutic agents |
EP1210330B1 (en) * | 1999-08-10 | 2005-04-20 | Vernalis (Oxford) Ltd | Antibacterial agents |
CN103435514B (en) * | 2013-08-01 | 2015-11-25 | 中国人民解放军军事医学科学院毒物药物研究所 | Matrix metallo-proteinase inhibitor and uses thereof |
WO2023235109A1 (en) * | 2022-06-01 | 2023-12-07 | University Of Massachusetts | Novel main protease inhibitors, and compositions and methods thereof |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4618708A (en) * | 1981-12-16 | 1986-10-21 | Bernard Roques | Amino acid derivative |
EP0214639A2 (en) * | 1985-09-10 | 1987-03-18 | G.D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
EP0236872A2 (en) * | 1986-03-11 | 1987-09-16 | F. Hoffmann-La Roche Ag | Hydroxyl amine derivatives, their preparation and use as medicaments |
WO1990005719A1 (en) * | 1988-11-23 | 1990-05-31 | British Bio-Technology Limited | Hydroxamic acid based collagenase inhibitors |
EP0498665A1 (en) * | 1991-02-07 | 1992-08-12 | British Biotech Pharmaceuticals Limited | Hydroxamic acids derivatives, process for their preparation and use thereof |
WO1992013545A1 (en) * | 1991-01-31 | 1992-08-20 | Abbott Laboratories | Endothelin converting enzyme inhibitors |
WO1993020047A1 (en) * | 1992-04-07 | 1993-10-14 | British Bio-Technology Limited | Hydroxamic acid based collagenase and cytokine inhibitors |
-
1992
- 1992-10-03 GB GB929220845A patent/GB9220845D0/en active Pending
-
1993
- 1993-10-01 AU AU48316/93A patent/AU4831693A/en not_active Abandoned
- 1993-10-01 WO PCT/GB1993/002044 patent/WO1994007527A2/en active Application Filing
Patent Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4618708A (en) * | 1981-12-16 | 1986-10-21 | Bernard Roques | Amino acid derivative |
EP0214639A2 (en) * | 1985-09-10 | 1987-03-18 | G.D. Searle & Co. | Hydroxamic acid based collagenase inhibitors |
EP0236872A2 (en) * | 1986-03-11 | 1987-09-16 | F. Hoffmann-La Roche Ag | Hydroxyl amine derivatives, their preparation and use as medicaments |
WO1990005719A1 (en) * | 1988-11-23 | 1990-05-31 | British Bio-Technology Limited | Hydroxamic acid based collagenase inhibitors |
WO1992013545A1 (en) * | 1991-01-31 | 1992-08-20 | Abbott Laboratories | Endothelin converting enzyme inhibitors |
EP0498665A1 (en) * | 1991-02-07 | 1992-08-12 | British Biotech Pharmaceuticals Limited | Hydroxamic acids derivatives, process for their preparation and use thereof |
WO1993020047A1 (en) * | 1992-04-07 | 1993-10-14 | British Bio-Technology Limited | Hydroxamic acid based collagenase and cytokine inhibitors |
Non-Patent Citations (3)
Title |
---|
J.H.AXELROD ET AL.: "Expression of Human Recombinant Pasminogen Activators Enhances Invasion and Experimental Metastasis of H-ras-Transformed NIH 3T3 Cells", MOL.CELL.BIOL., vol. 9, no. 5, May 1989 (1989-05-01), pages 2133 - 2141 * |
R.BERKOW, ED.: "the merck manual of diagnosis and therapy, 15th edition", MERCK & CO.,INC., RAHWAY, N.J. * |
R.REICH ET AL.: "Effects of Inhibitors of Plasminogen Activator, Serine Proteinases, and Collagenase IV on the Invasion of Basement Membranes by Metastatic Cells", CANCER RES., vol. 48, no. 12, 1988, pages 3307 - 3312 * |
Also Published As
Publication number | Publication date |
---|---|
WO1994007527A2 (en) | 1994-04-14 |
GB9220845D0 (en) | 1992-11-18 |
AU4831693A (en) | 1994-04-26 |
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