WO1994003610A3 - Isolation and cloning of a protein with tyrosine-phosphatase activity - Google Patents

Isolation and cloning of a protein with tyrosine-phosphatase activity Download PDF

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Publication number
WO1994003610A3
WO1994003610A3 PCT/EP1993/002036 EP9302036W WO9403610A3 WO 1994003610 A3 WO1994003610 A3 WO 1994003610A3 EP 9302036 W EP9302036 W EP 9302036W WO 9403610 A3 WO9403610 A3 WO 9403610A3
Authority
WO
WIPO (PCT)
Prior art keywords
tyrosine
cloning
isolation
protein
phosphatase activity
Prior art date
Application number
PCT/EP1993/002036
Other languages
French (fr)
Other versions
WO1994003610A2 (en
Inventor
Lucia Monaco
Antonella Isacchi
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Priority to AU47047/93A priority Critical patent/AU4704793A/en
Priority to EP93917704A priority patent/EP0652959A1/en
Publication of WO1994003610A2 publication Critical patent/WO1994003610A2/en
Publication of WO1994003610A3 publication Critical patent/WO1994003610A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)

Abstract

Mammalian receptor-type protein tyrosine phosphatases (PTPases) whose extracellular domains include an Arg-Gly-Asp sequence, and functional derivatives thereof. Examples of such PTPases are novel members of the Class II PTPase group.
PCT/EP1993/002036 1992-07-31 1993-07-29 Isolation and cloning of a protein with tyrosine-phosphatase activity WO1994003610A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU47047/93A AU4704793A (en) 1992-07-31 1993-07-29 Isolation and cloning of a protein with tyrosine-phosphatase activity
EP93917704A EP0652959A1 (en) 1992-07-31 1993-07-29 Isolation and cloning of a protein with tyrosine-phosphatase activity

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9216328.6 1992-07-31
GB929216328A GB9216328D0 (en) 1992-07-31 1992-07-31 Isolation and cloning of a protein with tyrosine-phosphatase activity

Publications (2)

Publication Number Publication Date
WO1994003610A2 WO1994003610A2 (en) 1994-02-17
WO1994003610A3 true WO1994003610A3 (en) 1994-03-31

Family

ID=10719632

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1993/002036 WO1994003610A2 (en) 1992-07-31 1993-07-29 Isolation and cloning of a protein with tyrosine-phosphatase activity

Country Status (8)

Country Link
EP (1) EP0652959A1 (en)
CN (1) CN1082110A (en)
AU (1) AU4704793A (en)
GB (1) GB9216328D0 (en)
IL (1) IL106505A0 (en)
MX (1) MX9304580A (en)
WO (1) WO1994003610A2 (en)
ZA (1) ZA935483B (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050032087A1 (en) 1990-07-11 2005-02-10 New York University Novel receptor-type phosphotyrosine phosphatase-alpha
US5604094A (en) * 1990-07-11 1997-02-18 New York University Receptor-type phosphotyrosine phosphatase-β
US6682905B1 (en) 1990-07-11 2004-01-27 New York University Receptor-type phosphotyrosine phosphatase-alpha
EP0708831B2 (en) 1994-05-03 2007-12-05 Cold Spring Harbor Laboratory Cell-density enhanced protein tyrosine phosphatases
EP0929683A1 (en) 1996-03-06 1999-07-21 ZymoGenetics, Inc. DIABETES MELLITUS 37 kD AUTOANTIGEN PROTEIN-TYROSINE PHOSPHATASE
WO1998000552A2 (en) * 1996-07-02 1998-01-08 President And Fellows Of Harvard College Receptor tyrosine phosphatase, and uses related thereto
JP3504672B2 (en) * 1996-12-20 2004-03-08 ノボザイムス アクティーゼルスカブ Peniophora phytase
US6060298A (en) * 1996-12-20 2000-05-09 Novo Nordisk A/S Peniophora phytase
JP2002537854A (en) 1999-03-08 2002-11-12 メルク フロスト カナダ アンド カンパニー Intact cell assay for protein tyrosine phosphatase
JP6311125B2 (en) * 2014-11-26 2018-04-18 パナソニックＩｐマネジメント株式会社 Washing machine
CN108823180A (en) * 2018-06-29 2018-11-16 云南大学 Make the dephosphorylized albumen of protein kinase B specific site and its nucleic acid

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992001050A1 (en) * 1990-07-11 1992-01-23 New York University Novel receptor-type phosphotyrosine phosphatase

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992001050A1 (en) * 1990-07-11 1992-01-23 New York University Novel receptor-type phosphotyrosine phosphatase

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
EMBL Database entry HSICA512 Accession number X62899; 12 November 1991 RABIN, D. et al.:' An IDDM-specific islet autoantigen, ICA-512, is a putative tyrosine *
KRUEGER, N. ET AL.: "Structural diversity and evolution of human receptor-like protein tyrosine phosphatases", EMBO JOURNAL, vol. 9, no. 10, October 1990 (1990-10-01), EYNSHAM, OXFORD GB, pages 3241 - 3252 *

Also Published As

Publication number Publication date
IL106505A0 (en) 1993-11-15
MX9304580A (en) 1994-02-28
WO1994003610A2 (en) 1994-02-17
AU4704793A (en) 1994-03-03
EP0652959A1 (en) 1995-05-17
GB9216328D0 (en) 1992-09-16
ZA935483B (en) 1994-02-28
CN1082110A (en) 1994-02-16

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