WO1994000587A3 - Attenuated equine herpesvirus-4 as live vaccine or recombinant vector - Google Patents
Attenuated equine herpesvirus-4 as live vaccine or recombinant vector Download PDFInfo
- Publication number
- WO1994000587A3 WO1994000587A3 PCT/GB1993/001355 GB9301355W WO9400587A3 WO 1994000587 A3 WO1994000587 A3 WO 1994000587A3 GB 9301355 W GB9301355 W GB 9301355W WO 9400587 A3 WO9400587 A3 WO 9400587A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- equine herpesvirus
- recombinant vector
- live vaccine
- attenuated equine
- attenuated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16722—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16741—Use of virus, viral particle or viral elements as a vector
- C12N2710/16743—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16711—Varicellovirus, e.g. human herpesvirus 3, Varicella Zoster, pseudorabies
- C12N2710/16761—Methods of inactivation or attenuation
Abstract
The present invention is concerned with an attenuated Equine herpesvirus-4 vaccine. The attenuation is achieved by a mutation into a gene of Equine herpesvirus-4 defined in SEQ ID NO: 1. The invention also relates to a vector vaccine comprising an Equine herpesvirus-4 mutant having a foreign gene inserted into the Equine herpesvirus-4 genome.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929213882A GB9213882D0 (en) | 1992-06-30 | 1992-06-30 | Live modified equine herpesvirus-4 vaccine |
GB9213882.5 | 1992-06-30 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1994000587A2 WO1994000587A2 (en) | 1994-01-06 |
WO1994000587A3 true WO1994000587A3 (en) | 1994-02-17 |
Family
ID=10717952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/GB1993/001355 WO1994000587A2 (en) | 1992-06-30 | 1993-06-29 | Attenuated equine herpesvirus-4 as live vaccine or recombinant vector |
Country Status (2)
Country | Link |
---|---|
GB (1) | GB9213882D0 (en) |
WO (1) | WO1994000587A2 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5741696A (en) * | 1992-08-07 | 1998-04-21 | Syntro Corporation | Recombinant equine herpesviruses |
GB9626029D0 (en) | 1996-12-14 | 1997-01-29 | Univ Leeds | EVH-1 vectors |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2185024A (en) * | 1985-12-04 | 1987-07-08 | Medical Res Council | Peptide inhibitor of ribonucleotide reductase |
WO1990002802A2 (en) * | 1988-09-13 | 1990-03-22 | Institute For Animal Health Limited | Viral nucleotide sequences |
EP0447303A1 (en) * | 1990-03-12 | 1991-09-18 | Rhone Merieux S.A. | Recombinant herpes viruses, particularly for realization of vaccines, preparation process therefor, realized plasmids during this process and obtained vaccines |
WO1992001045A1 (en) * | 1990-07-06 | 1992-01-23 | The University Court Of The University Of Glasgow | Equine herpesvirus-4 tk- vaccine |
EP0507179A2 (en) * | 1991-04-05 | 1992-10-07 | Bayer Ag | Equine herpes viruses (EHV) containing foreign DNA, process for their preparation and their use as vaccines |
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1992
- 1992-06-30 GB GB929213882A patent/GB9213882D0/en active Pending
-
1993
- 1993-06-29 WO PCT/GB1993/001355 patent/WO1994000587A2/en active Application Filing
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB2185024A (en) * | 1985-12-04 | 1987-07-08 | Medical Res Council | Peptide inhibitor of ribonucleotide reductase |
WO1990002802A2 (en) * | 1988-09-13 | 1990-03-22 | Institute For Animal Health Limited | Viral nucleotide sequences |
EP0447303A1 (en) * | 1990-03-12 | 1991-09-18 | Rhone Merieux S.A. | Recombinant herpes viruses, particularly for realization of vaccines, preparation process therefor, realized plasmids during this process and obtained vaccines |
WO1992001045A1 (en) * | 1990-07-06 | 1992-01-23 | The University Court Of The University Of Glasgow | Equine herpesvirus-4 tk- vaccine |
EP0507179A2 (en) * | 1991-04-05 | 1992-10-07 | Bayer Ag | Equine herpes viruses (EHV) containing foreign DNA, process for their preparation and their use as vaccines |
Non-Patent Citations (2)
Title |
---|
JOURNAL OF GENERAL VIROLOGY vol. 69, no. 7, July 1988, pages 1575 - 1590 CULLINANE, A.A. ET AL. 'Characterization of the genome of Equine Herpesvirus 1 subtype 2' * |
JOURNAL OF VIROLOGY vol. 63, no. 3, March 1989, pages 1123 - 1133 RIGGIO, M.P. ET AL. 'Identification and nucleotide sequence of the glycoprotein gB gene of Equine Herpesvirus 4' cited in the application * |
Also Published As
Publication number | Publication date |
---|---|
GB9213882D0 (en) | 1992-08-12 |
WO1994000587A2 (en) | 1994-01-06 |
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