WO1993014760A3 - Methods - Google Patents
Methods Download PDFInfo
- Publication number
- WO1993014760A3 WO1993014760A3 PCT/US1993/000730 US9300730W WO9314760A3 WO 1993014760 A3 WO1993014760 A3 WO 1993014760A3 US 9300730 W US9300730 W US 9300730W WO 9314760 A3 WO9314760 A3 WO 9314760A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- human
- methods
- hiv
- delaying
- aids
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
- A61K31/404—Indoles, e.g. pindolol
- A61K31/405—Indole-alkanecarboxylic acids; Derivatives thereof, e.g. tryptophan, indomethacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/256,708 US5482959A (en) | 1992-01-28 | 1993-01-27 | Method for delaying aids in an HIV infected individual by administration of substituted azaspirane compounds |
AU35951/93A AU666175B2 (en) | 1992-01-28 | 1993-01-27 | A method for delaying HIV induced AIDS by administration of substituted azasperane compounds |
KR1019940702596A KR950700068A (en) | 1992-01-28 | 1993-01-27 | A method for delaying HIV in-duced AIDS by administration of substituted azasperane compounds by administering a substituted azaspiran compound |
EP93904671A EP0624089A4 (en) | 1992-01-28 | 1993-01-27 | Methods. |
JP5513407A JPH07503252A (en) | 1992-01-28 | 1993-01-27 | Method for delaying HIV-induced AIDS by administration of substituted azasperane compounds |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9201803.5 | 1992-01-28 | ||
GB929201803A GB9201803D0 (en) | 1992-01-28 | 1992-01-28 | Methods |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1993014760A2 WO1993014760A2 (en) | 1993-08-05 |
WO1993014760A3 true WO1993014760A3 (en) | 1993-09-02 |
Family
ID=10709398
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1993/000730 WO1993014760A2 (en) | 1992-01-28 | 1993-01-27 | Methods |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0624089A4 (en) |
JP (1) | JPH07503252A (en) |
KR (1) | KR950700068A (en) |
AU (1) | AU666175B2 (en) |
CA (1) | CA2128535A1 (en) |
GB (1) | GB9201803D0 (en) |
WO (1) | WO1993014760A2 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9315351D0 (en) * | 1993-07-23 | 1993-09-08 | Smithkline Beecham Corp | Methods |
GB9315340D0 (en) * | 1993-07-23 | 1993-09-08 | Smithkline Beecham Corp | Methods |
GB9315306D0 (en) * | 1993-07-23 | 1993-09-08 | Smithkline Beecham Corp | Methods |
US7273859B2 (en) * | 2004-05-12 | 2007-09-25 | Bristol-Myers Squibb Company | HIV integrase inhibitors: cyclic pyrimidinone compounds |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US181704A (en) * | 1876-08-29 | Improvement in flour-dressing machines | ||
US4963557A (en) * | 1987-09-28 | 1990-10-16 | Smithkline Beecham Corporation | Immunomodulatory azaspiranes |
WO1992004899A1 (en) * | 1990-09-24 | 1992-04-02 | Smithkline Beecham Corporation | Methods |
ZA921120B (en) * | 1991-02-19 | 1993-01-27 | Smithkline Beecham Corp | Cytokine inhibitors |
-
1992
- 1992-01-28 GB GB929201803A patent/GB9201803D0/en active Pending
-
1993
- 1993-01-27 WO PCT/US1993/000730 patent/WO1993014760A2/en not_active Application Discontinuation
- 1993-01-27 CA CA002128535A patent/CA2128535A1/en not_active Abandoned
- 1993-01-27 EP EP93904671A patent/EP0624089A4/en not_active Withdrawn
- 1993-01-27 KR KR1019940702596A patent/KR950700068A/en not_active Application Discontinuation
- 1993-01-27 JP JP5513407A patent/JPH07503252A/en active Pending
- 1993-01-27 AU AU35951/93A patent/AU666175B2/en not_active Ceased
Non-Patent Citations (4)
Title |
---|
CHEMICAL ABSTRACTS, Volume 111, No. 17, Abstract No. 153616r, issued 23 October 1989, (Columbus, Ohio, USA), BADGER et al., "Preparation of N-Aminoakyl-2-Azaspiro(4.5)Decanes and Analogs as Immunosuppressants", (Dept. Immumol., SmitKline Beckmann Corp., King of Prussia, PA 19406-0939 USA); & EP,A,310 * |
CHEMICAL ABSTRACTS, Volume 113, No. 21, Abstract No. 191085r, issued 19 November 1990, (Columbus, Ohio, USA), BADGER et al., "Antiarthritic and Suppressor Cell Inducing Activity of Azaspiranes: Structure-Function Relationships of a Novel Class of Immunomodulatory Agents", (Dept. Immumol., SmithKline and French Lab., King of * |
CHEMICAL ABSTRACTS, Volume 86, No. 9, Abstract No. 55229n, issued 28 February 1977, (Columbus, Ohio, USA), EL-TELBANY et al., "Synthesis of Certain Spiro Compounds for Pharmacological Study. Part II", (Fac. Pharm., Cairo, Egypt); & J. PHARM. BELG., 1976, 31(4), pp. 403-10. * |
See also references of EP0624089A4 * |
Also Published As
Publication number | Publication date |
---|---|
EP0624089A1 (en) | 1994-11-17 |
WO1993014760A2 (en) | 1993-08-05 |
AU3595193A (en) | 1993-09-01 |
JPH07503252A (en) | 1995-04-06 |
GB9201803D0 (en) | 1992-03-11 |
CA2128535A1 (en) | 1993-08-05 |
AU666175B2 (en) | 1996-02-01 |
KR950700068A (en) | 1995-01-16 |
EP0624089A4 (en) | 1994-12-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
WO1996006620A3 (en) | Lipid analogs for treating viral infections | |
AU2045192A (en) | Compounds and methods for inhibition of hiv and related viruses | |
EP0831873A4 (en) | The treatment of hiv and other viral infections using combinatory therapy | |
EP0640345A3 (en) | Composition for inhibiting transmission of AIDS, containing silver salts with a detergent | |
AU4019289A (en) | Hiv protease inhibitors useful for the treatment of aids | |
AU4028895A (en) | Vaccine and treatment method of Human Immunodeficiency Virus | |
AU7786387A (en) | Composition of matter and method of immunizing against viral causative agents of aids and arc | |
AU8693491A (en) | Synergism of hiv reverse transcriptase inhibitors | |
ZA964679B (en) | Genetically altered feline immunodeficiency viruses and their use as an effective vaccine against feline immunodeficiency virus infection. | |
AU5848794A (en) | Multiple-gene mutants of human immunodeficiency virus (hiv) for vaccine use | |
AU4426289A (en) | Methods for interfering with hiv multiplication and composition for the treatment of aids | |
AU1308188A (en) | Methods of treating acquired immune deficiency syndrome (AIDS) caused by human immunodeficiency virus (HIV) | |
WO1993014760A3 (en) | Methods | |
AU3530293A (en) | Compositions for the treatment of infection and disease caused by hepatitis B virus (HBV) | |
WO1990013281A3 (en) | Method of suppressing hiv infection | |
AU1193988A (en) | Method of inhibiting the transmission of aids virus | |
AU7212694A (en) | Inhibition of human immunodeficiency virus reproduction by deoxyribonuclease i | |
AU2833789A (en) | Non-reverting rna viruses | |
AU4829190A (en) | Methods and compositions for the prophylaxis and treatment of hepatitis b virus infections | |
ZA945416B (en) | Method of inhibiting the production of infectious human immunodeficiency viruses (HIV) in HIV seropositive humans. | |
ZA945418B (en) | Method of inhibiting the replication of human immunodeficiency viruses (HIV) in HIV seropositive humans. | |
IL102815A0 (en) | Pharmaceutical compositions and method for the treatment of infection caused by the human immunodeficiency virus | |
EP0316592A3 (en) | 3'-fluoro-2',3'-dideoxyuridine, and its therapeutic application | |
ZA945417B (en) | Method of inhibiting cellular entry of human immunodeficiency viruses NHIV) in HIV seropositive humans. | |
AU5000796A (en) | Process for the deactivation of hiv and other viruses |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
AK | Designated states |
Kind code of ref document: A2 Designated state(s): AU CA JP KR US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A2 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE |
|
AK | Designated states |
Kind code of ref document: A3 Designated state(s): AU CA JP KR US |
|
AL | Designated countries for regional patents |
Kind code of ref document: A3 Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE |
|
CFP | Corrected version of a pamphlet front page |
Free format text: REVISED TITLE RECEIVED BY THE INTERNATIONAL BUREAU AFTER COMPLETION OF THE TECHNICAL PREPARATIONS FOR INTERNATIONAL PUBLICATION |
|
DFPE | Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101) | ||
WWE | Wipo information: entry into national phase |
Ref document number: 2128535 Country of ref document: CA |
|
WWE | Wipo information: entry into national phase |
Ref document number: 08256708 Country of ref document: US |
|
WWE | Wipo information: entry into national phase |
Ref document number: 1993904671 Country of ref document: EP |
|
WWP | Wipo information: published in national office |
Ref document number: 1993904671 Country of ref document: EP |
|
WWW | Wipo information: withdrawn in national office |
Ref document number: 1993904671 Country of ref document: EP |